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Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 4/2014, Volume 111, Issue 13, pp. 5024 - 5029
The visual cycle is a series of enzyme-catalyzed reactions which converts all-trans-retinal to 11-cis-retinal for the regeneration of visual pigments in rod... 
ATP binding cassette transporters | Retinal pigments | Isomerization | Adenosine triphosphatases | Photoreceptors | Lipids | Retinoids | Liposomes | Isomers | Retinal diseases | Retinal pigment epithelial cells | ABC transporters | Stargardt disease | Photoreceptor degeneration | LIPOFUSCIN | ROD | MULTIDISCIPLINARY SCIENCES | photoreceptor degeneration | IDENTIFICATION | OUTER SEGMENTS | RIM PROTEIN | STARGARDT MACULAR DYSTROPHY | DOCOSAHEXAENOIC ACID | DISEASE | retinal pigment epithelial cells | N-RETINYLIDENE-PHOSPHATIDYLETHANOLAMINE | retinoids | RETINAL-PIGMENT EPITHELIUM | Retinoids - metabolism | Vitamin A - chemistry | Rod Cell Outer Segment - metabolism | Rod Cell Outer Segment - drug effects | Photoreceptor Cells, Vertebrate - drug effects | Proteolipids - metabolism | Vitamin A - toxicity | Photoreceptor Cells, Vertebrate - cytology | Phosphatidylcholines - metabolism | Isomerism | Animals | Cattle | Models, Biological | Adenosine Triphosphate - metabolism | Retinoids - chemistry | Cytoprotection - drug effects | ATP-Binding Cassette Transporters - metabolism | Biological Transport - drug effects | Mice | Phosphatidylethanolamines - metabolism | Photoreceptor Cells, Vertebrate - metabolism | Phosphatidylethanolamines - chemistry | Sus scrofa | Protein research | Carrier proteins | Physiological aspects | Research | Adenosine triphosphate | Macular degeneration | Retina | Membranes | Adenosine triphosphatase | Binding sites | Cell cycle | Index Medicus | Biological Sciences
Journal Article
Biochemical and biophysical research communications, 08/2019
The human retina-specific ATP binding cassette transporter, ABCA4, plays a significant role in the visual cycle. Mutations in the ABCA4 gene result in a broad... 
Index Medicus
Journal Article
Protein Expression and Purification, ISSN 1046-5928, 05/2014, Volume 97, pp. 50 - 60
Journal Article
Journal Article
FEBS JOURNAL, ISSN 1742-464X, 09/2011, Volume 278, Issue 18, pp. 3204 - 3214
Mutations to members of the A subfamily of ATP binding cassette (ABC) proteins are responsible for a number of diseases; typically they are associated with... 
TRANSPORTER ABCA4 | VISUAL CYCLE | ROD OUTER SEGMENTS | LIGHT-INDUCED DAMAGE | phospholipid translocase | BIOCHEMISTRY & MOLECULAR BIOLOGY | DISK MEMBRANES | all-trans-retinal | P-GLYCOPROTEIN | LIPOFUSCIN FLUOROPHORE | DISEASE GENE ABCR | STARGARDT MACULAR DYSTROPHY | ALL-TRANS-RETINOL | Stargardt disease | ABC transporter
Journal Article
Genetics and molecular research : GMR, ISSN 1676-5680, 2012, Volume 11, Issue 4, pp. 4342 - 4350
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 11/2013, Volume 288, Issue 48, pp. 34414 - 34426
Background: Lipid transport by the A-subfamily of ATP-binding cassette (ABC) transporters implicated in human disorders is poorly understood. Results: ABCA1... 
ABCA1 | Tangier Disease | Cholesterol Metabolism | High Density Lipoprotein (HDL) | BIOCHEMISTRY & MOLECULAR BIOLOGY | ABCA4 | Phospholipid | APOA-I | IDENTIFICATION | Membrane Reconstitution | CELLULAR LIPID EFFLUX | Stargardt Disease | TANGIER-DISEASE | Lipid Transport | RIM PROTEIN | ABC Transporter | CHOLESTEROL EFFLUX | PURIFICATION | MUTATIONS | N-RETINYLIDENE-PHOSPHATIDYLETHANOLAMINE | APOLIPOPROTEIN-A-I | Lipoproteins, HDL - genetics | ATP Binding Cassette Transporter 1 - isolation & purification | Humans | Phosphatidylcholines - metabolism | ATP Binding Cassette Transporter 1 - metabolism | Lipoproteins, HDL - biosynthesis | ATP-Binding Cassette Transporters - genetics | Tangier Disease - metabolism | HEK293 Cells | ATP-Binding Cassette Transporters - metabolism | Lipid Metabolism - genetics | Phospholipids - metabolism | Sphingomyelins - metabolism | Tangier Disease - genetics | Phosphatidylserines - metabolism | Apolipoprotein A-I - metabolism | Cholesterol - metabolism | ATP-Binding Cassette Transporters - isolation & purification | Macular Degeneration - metabolism | Macular Degeneration - genetics | Tangier Disease - pathology | Mutation | Phosphatidylethanolamines - metabolism | Genome, Human | Homeostasis - genetics | ATP Binding Cassette Transporter 1 - genetics | Macular Degeneration - pathology | Index Medicus | Membrane Biology
Journal Article