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Journal Article
Lipids in health and disease, ISSN 1476-511X, 2019, Volume 18, Issue 1, pp. 2 - 7
Background: ATP-binding cassette (ABC) transporters are involved in a huge range of physiological processes... 
ATP-binding cassette transporters | NUTRITION & DIETETICS | BIOCHEMISTRY & MOLECULAR BIOLOGY | Abcc6 | MOUSE | Pseudoxanthoma elasticum | Mice | MUTATIONS | SECRETION | Gene expression | PCR | Liver - pathology | Kidney - pathology | Lipoproteins - genetics | Adipose Tissue, White - metabolism | Male | ATP Binding Cassette Transporter, Subfamily G, Member 1 - metabolism | ATP-Binding Cassette Transporters - deficiency | Kidney - metabolism | ATP Binding Cassette Transporter, Subfamily G, Member 1 - genetics | ATP-Binding Cassette Transporters - genetics | Biological Transport | ATP Binding Cassette Transporter, Subfamily G, Member 8 - metabolism | Lipoproteins - metabolism | ATP-Binding Cassette Transporters - metabolism | Female | ATP Binding Cassette Transporter, Subfamily B - genetics | ATP Binding Cassette Transporter, Subfamily G, Member 8 - genetics | ATP Binding Cassette Transporter, Subfamily G, Member 5 - metabolism | Disease Models, Animal | ATP Binding Cassette Transporter, Subfamily B, Member 11 - metabolism | ATP Binding Cassette Transporter, Subfamily G, Member 5 - genetics | Adipose Tissue, White - pathology | Pseudoxanthoma Elasticum - metabolism | Liver - metabolism | Gene Expression Regulation | Bile Acids and Salts - metabolism | Pseudoxanthoma Elasticum - pathology | Cholesterol - metabolism | ATP Binding Cassette Transporter, Subfamily B - metabolism | Disease Progression | Mice, Knockout | ATP Binding Cassette Transporter, Subfamily B, Member 11 - genetics | ATP Binding Cassette Transporter, Subfamily D - genetics | Animals | ATP Binding Cassette Transporter, Subfamily D - metabolism | Pseudoxanthoma Elasticum - genetics | Research | Tissues | Adenosine triphosphate | Calcification (ectopic) | Adipose tissue | Disease | Gene regulation | Liver | Homeostasis | Lipids | Phospholipids | ABCA1 protein | Sterols | Metabolites | Mineralization | Rodents | Fibroblasts | Physiology | ABC transporters | Lipid metabolism | Age | Kidneys | Metabolism | Cholesterol | Lipoproteins | Calcification | ATP-binding protein | Mutation | ABC transporter | Bile
Journal Article
Journal Article
Acta Pharmaceutica Sinica B, ISSN 2211-3835, 05/2017, Volume 7, Issue 3, pp. 260 - 280
Oral drug absorption is a process influenced by the physicochemical and biopharmaceutical properties of the drug and its inter-relationship with the... 
Formulation strategies | Factors affecting absorption | BCS | Permeability | Solubility | FORMULATION DEVELOPMENT | Formulations strategies | SOLID DISPERSION | BIORELEVANT DISSOLUTION MEDIA | POLYMERIC MICELLES | DRUG-DELIVERY-SYSTEMS | EQUILIBRIUM SOLUBILITY | MESOPOROUS SILICON MICROPARTICLES | NANOSTRUCTURED LIPID CARRIERS | ORAL BIOAVAILABILITY | PHARMACOLOGY & PHARMACY | IN-VIVO EVALUATION | AZT, azidothymidine | PEG, polyethylene glycol | P-gp, P-glycoprotein | MCT, monocarboxylate transporter | VDAD, volume to dissolve applied dose | OMM, ordered mesoporous material | vit. E TPGS, vitamin E tocopherol polyethylene glycol succinate | SLC, solute carrier | ABC, ATP-binding cassette | GRAS, generally recognized as safe | BE, bioavailability | SPIP, single pass intestinal perfusion | OAT, organic anion transporter | NLC, nanostructured lipid carrier | GIS, gastrointestinal simulator | IR, immediate release | PAMPA, parallel artificial membrane permeability assay | SGLT, sodium dependent secondary active transporter | AP, absorption potential | SDS, sodium dodecyl sulphate | CD, cyclodextrin | SIF, simulated intestinal fluid | bioequivalence | FDA, U.S. Food and Drug Administration | RFC, reduced folate transporter | BSP, bromosulfophthalein | Psi, porous silicon | FeSSIF, fed state simulated intestinal fluid | FaSSIF, fasted state simulated intestinal fluid | Peff, effective permeability | EMEA, European Medicines Agency | OCTN, organic cationic | CNT, concentrative nucleoside transporter | PAH, p-aminohippurate | carnitine transporter | OATP, organic anion transporting polypeptide | D:S, dose:solubility | BCRP, breast cancer resistance protein | OCT, organic cationic transporter | MPP, 1-methyl-4-phenylpyridinium | MRP, multidrug resistance associated protein | SLCO, solute carrier organic anion | SMVT, sodium dependent multivitamin transporter | ISBT, sodium dependent bile salt transporter | TEOS, tetraethylortho silicate | Review | CNT, Na+-dependent concentrative transporter | UWL, unstirred water layer | E217G, estradiol 17β-glucuronide | PMAT, plasma membrane monoamine transport | IDR, intrinsic dissolution rate | PVDF, polyvinylidene difluoride | SVCT, sodium-dependent vitamin C transporter | HPC-SL, LBDDS, lipid based drug delivery system | WHO, World Health Organization | ATP, adenosine triphosphate | BCS, biopharmaceutical classification system | CYP, cytochrome P450 | HIV, human immunodeficiency disease | FIP, International Pharmaceutical Federation | GLUT, sodium-independent facilitated diffusion transporter | PSA, polar surface area | NTCP, sodium-dependent taurocholate co-transporting polypeptide | ENT, equilibrative nucleoside transporter | GITA, gastrointestinal transit and absorption | HUGO, Human Genome Organization | PGA, polyglycolic acid | NME, new molecular entity | API, active pharmaceutical ingredient | PLA, poly(lactic acid) | BDDS, biopharmaceutical drug disposition system | GIT, gastrointestinal tract | Papp, apparent permeability | PLGA, poly-d,l-lactide-co-glycoside | PEPT, peptide transporter | pMMA, polymethyl methacrylate | SUPAC, scale-up and post approval changes | CDER, Centre for Drug Evaluation and Research | PEI, polyethyleneimine | FATP, fatty acid transporter protein | ICH, International Council of Harmonization | SLN, solid lipid nanoparticles
Journal Article