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Pharmaceutical Research, ISSN 0724-8741, 12/2017, Volume 34, Issue 12, pp. 2477 - 2487
Breast cancer resistance protein (BCRP/ABCG2) has previously been identified with high expression levels in human lung. The subcellular localisation and... 
Biochemistry, general | Biomedical Engineering | Biomedicine | Pharmacy | NCI-H441 cells | pulmonary drug disposition | inhalation biopharmaceutics | Medical Law | drug absorption | Pharmacology/Toxicology | ABC transporter | TRANSPORTER | DRUG-DELIVERY | A549 | INVOLVEMENT | TANDEM MASS-SPECTROMETRY | CHEMISTRY, MULTIDISCIPLINARY | INHIBITION | LINE NCL-H441 | FUNCTIONAL EXPRESSION | PHARMACOLOGY & PHARMACY | MULTIDRUG-RESISTANCE | ABCG2 | Cell Line | Gene Expression | Respiratory Mucosa - cytology | ATP Binding Cassette Transporter, Subfamily G, Member 2 - metabolism | Alveolar Epithelial Cells - cytology | Humans | ATP Binding Cassette Transporter, Subfamily G, Member 2 - genetics | Cells, Cultured | Alveolar Epithelial Cells - metabolism | Lung - cytology | Neoplasm Proteins - metabolism | Biological Transport | Cell Transdifferentiation | Neoplasm Proteins - analysis | Lung - metabolism | Respiratory Mucosa - metabolism | ATP Binding Cassette Transporter, Subfamily G, Member 2 - analysis | Neoplasm Proteins - genetics | Breast cancer | Cell culture | Membranes | Transcription | Epithelial cells | Lung | Confocal microscopy | Confocal | Cytosol | Nuclei | Proteins | Localization | Alveoli | Efflux | Substrate inhibition | Abundance | Cell membranes | Cell membranes (biology) | Epithelium | Prazosin | Microscopy | Nuclei (cytology) | Position (location) | Transporter | Scanning microscopy | Cancer | Index Medicus
Journal Article
Journal Article
Journal Article
Molecular Pharmacology, ISSN 0026-895X, 03/2008, Volume 73, Issue 3, pp. 845 - 854
Journal Article
ADVANCED DRUG DELIVERY REVIEWS, ISSN 0169-409X, 01/2009, Volume 61, Issue 1, pp. 66 - 72
Human ATP-binding cassette (ABC) transporter ABCG2 (BCRP/MXR/ABCP) is a plasma membrane protein carrying intra- and inter-molecular disulfide bonds and an... 
Ubiquitin | CASSETTE TRANSPORTER ABCG2 | Lysosome | ER-ASSOCIATED DEGRADATION | N-glycosylation | PLASMA-MEMBRANE | MEMBRANE LOCALIZATION | ERAD | GENE | Disulfide bond | N-LINKED GLYCOSYLATION | PHARMACOLOGY & PHARMACY | CYSTIC-FIBROSIS | Endosome | EXPRESSION | SINGLE-NUCLEOTIDE POLYMORPHISMS | Proteasome | CANCER RESISTANCE PROTEIN
Journal Article
Journal Article
JOURNAL OF NUCLEAR MEDICINE, ISSN 0161-5505, 08/2013, Volume 54, Issue 8, pp. 1181 - 1187
The adenosine triphosphate-binding cassette transporters P-glycoprotein (Pgp) and breast cancer resistance protein (BCRP) are 2 major gatekeepers at the blood... 
blood-brain barrier | breast cancer resistance protein | TRANSPORTERS | C-11-tariquidar | RADIOTRACER | BCRP/ABCG2 | P-glycoprotein | POSITRON-EMISSION-TOMOGRAPHY | INHIBITION | C-11-elacridar | PHARMACOKINETICS | SUBSTRATE | IN-VIVO | TARIQUIDAR | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | PET
Journal Article
Canadian Journal of Physiology and Pharmacology, ISSN 0008-4212, 12/2006, Volume 84, Issue 12, pp. 1251 - 1258
Journal Article
AMERICAN JOURNAL OF EPIDEMIOLOGY, ISSN 0002-9262, 05/2013, Volume 177, Issue 9, pp. 923 - 932
Journal Article
American Journal of Epidemiology, ISSN 0002-9262, 05/2013, Volume 177, Issue 9, pp. 923 - 932
  A loss-of-function mutation (Q141K, rs2231142) in the ATP-binding cassette, subfamily G, member 2 gene (ABCG2) has been shown to be associated with serum... 
ABCG2 protein, human | gout | polymorphism, single nucleotide | meta-analysis | genetic association studies | urate transporter | uric acid | Genotype & phenotype | Rheumatism | Mutation | Genes | Genomics | Polymorphism
Journal Article
Journal of Pharmaceutical Sciences, ISSN 0022-3549, 03/2013, Volume 102, Issue 3, pp. 787 - 793
Breast cancer resistance protein (BCRP), an efflux transporter expressed at the bile canalicular membrane, is responsible for the biliary clearance of many... 
hepatobiliary disposition | drug transport | ABC transporters | genetic polymorphisms | hepatic transport | Breast cancer resistance protein | Drug transport | Hepatic transport | Hepatobiliary disposition | Genetic polymorphisms | CHEMISTRY, MEDICINAL | MESSENGER-RNA EXPRESSION | ABC TRANSPORTER ABCG2 | TRANSPLANT RECIPIENTS | 421C-GREATER-THAN-A POLYMORPHISM | CHEMISTRY, MULTIDISCIPLINARY | CELL CARCINOMA | BCRP GENE POLYMORPHISMS | UDP-GLUCURONOSYLTRANSFERASES | CYCLOSPORINE-A | PHARMACOLOGY & PHARMACY | HUMAN LIVER | ABSOLUTE QUANTIFICATION | ATP Binding Cassette Transporter, Sub-Family G, Member 2 | Liver - pathology | Age Factors | Humans | Middle Aged | Gene Expression Regulation, Neoplastic | Male | Young Adult | ATP-Binding Cassette Transporters - genetics | Sensitivity and Specificity | Adult | Female | Neoplasm Proteins - genetics | Child | Tandem Mass Spectrometry - methods | Liver - metabolism | RNA, Messenger - genetics | Genotype | Calibration | ATP-Binding Cassette Transporters - analysis | Breast Neoplasms - genetics | Breast Neoplasms - pathology | Adolescent | Sex Factors | Neoplasm Proteins - analysis | Aged | Polymorphism, Single Nucleotide | Care and treatment | Peptides | Metabolites | RNA | Analysis | Physiological aspects | Breast cancer | Genetic aspects | Mass spectrometry | Cancer | Index Medicus
Journal Article