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1. Full Text Pomegranate polyphenolics suppressed azoxymethane-induced colorectal aberrant crypt foci and inflammation: Possible role of miR-126/VCAM-1 and miR-126/PI3K/ AKT/mTOR
by Banerjee, Nivedita and Kim, Hyemee and Talcott, Stephen and Mertens-Talcott, Susanne
Carcinogenesis (New York), ISSN 0143-3334, 12/2013, Volume 34, Issue 12, pp. 2814 - 2822
Life Sciences & Biomedicine | Oncology | Science & Technology | Inflammation - chemically induced | TOR Serine-Threonine Kinases - metabolism | Colorectal Neoplasms - genetics | Humans | Polyphenols - pharmacology | Male | MicroRNAs - metabolism | Azoxymethane - adverse effects | Proto-Oncogene Proteins c-akt - genetics | Aberrant Crypt Foci - genetics | Inflammation - metabolism | TOR Serine-Threonine Kinases - genetics | Cyclooxygenase 2 - genetics | Inflammation - drug therapy | Vascular Cell Adhesion Molecule-1 - genetics | Punicaceae | Beverages | Proto-Oncogene Proteins c-akt - metabolism | Anticarcinogenic Agents - pharmacology | Phosphatidylinositol 3-Kinase - metabolism | Colorectal Neoplasms - metabolism | Aberrant Crypt Foci - drug therapy | Aberrant Crypt Foci - chemically induced | Rats | Colorectal Neoplasms - chemically induced | Rats, Sprague-Dawley | Aberrant Crypt Foci - metabolism | HT29 Cells | Animals | Nitric Oxide Synthase Type II - genetics | Phosphatidylinositol 3-Kinase - genetics | Cyclooxygenase 2 - metabolism | Cell Line, Tumor | Inflammation - genetics | Cell Proliferation - drug effects | Colorectal Neoplasms - diet therapy | MicroRNAs - genetics | Vascular Cell Adhesion Molecule-1 - metabolism | Nitric Oxide Synthase Type II - metabolism | Index Medicus
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2. Full Text Protective effect of metformin in an aberrant crypt foci model induced by 1,2‐dimethylhydrazine: Modulation of oxidative stress and inflammatory process
by Bordini, Heloíza Paranzini and Kremer, Jean Lucas and Fagundes, Tatiane Renata and Melo, Gabriella Pasqual and Conchon‐Costa, Ivete and da Silva, Suelen Santos and Cecchini, Alessandra Lourenço and Panis, Carolina and Luiz, Rodrigo Cabral
Molecular carcinogenesis, ISSN 0899-1987, 03/2017, Volume 56, Issue 3, pp. 913 - 922
aberrant crypt foci | metformin | colorectal cancer | 1,2‐dimethylhydrazine | prevention | 1,2-dimethylhydrazine | Biochemistry & Molecular Biology | Oncology | Life Sciences & Biomedicine | Science & Technology | Aberrant Crypt Foci - chemically induced | AMP-Activated Protein Kinases - metabolism | Metformin - pharmacology | Colorectal Neoplasms - prevention & control | 1,2-Dimethylhydrazine - toxicity | Treatment Outcome | Aberrant Crypt Foci - immunology | Colorectal Neoplasms - chemically induced | Aberrant Crypt Foci - metabolism | Animals | Colorectal Neoplasms - immunology | Signal Transduction - drug effects | Neoplasms, Experimental | Female | Cell Proliferation - drug effects | Mice | Metformin - administration & dosage | Oxidative Stress - drug effects | Colorectal Neoplasms - metabolism | Aberrant Crypt Foci - prevention & control | Oxidative stress | Analysis | Hypoglycemic agents | Pharmacology | Nitric oxide | Colorectal cancer | Index Medicus
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3. Full Text A novel myokine, secreted protein acidic and rich in cysteine (SPARC), suppresses colon tumorigenesis via regular exercise
by Aoi, Wataru and Naito, Yuji and Takagi, Tomohisa and Tanimura, Yuko and Takanami, Yoshikazu and Kawai, Yukari and Sakuma, Kunihiro and Hang, Liu Po and Mizushima, Katsura and Hirai, Yasuko and Koyama, Ryota and Wada, Sayori and Higashi, Akane and Kokura, Satoshi and Ichikawa, Hiroshi and Yoshikawa, Toshikazu
Gut, ISSN 0017-5749, 06/2013, Volume 62, Issue 6, pp. 882 - 889
Gastroenterology & Hepatology | Life Sciences & Biomedicine | Science & Technology | Tumor Suppressor Proteins - metabolism | Oligonucleotide Array Sequence Analysis | Colonic Neoplasms - prevention & control | Humans | Glycoproteins - metabolism | Male | Muscle Fibers, Skeletal - metabolism | Physical Conditioning, Animal - physiology | Cell Transformation, Neoplastic - metabolism | Colonic Neoplasms - metabolism | Mice, Inbred ICR | Mice, Knockout | Aberrant Crypt Foci - metabolism | Colonic Neoplasms - physiopathology | Animals | Osteonectin | Aberrant Crypt Foci - physiopathology | Exercise - physiology | Mice | Apoptosis - physiology | Tumor Cells, Cultured | Aberrant Crypt Foci - prevention & control | Prevention | Colon cancer | Exercise | Physiological aspects | Tumor suppressor genes | Research | Muscle proteins | Health aspects | Review boards | Colorectal cancer | Cardiovascular disease | Metabolism | Experiments | Variance analysis | Epidemiology | Studies | Proteins | Musculoskeletal system | Physical fitness | Rodents | Tumorigenesis | Diabetes | Apoptosis | Index Medicus | Abridged Index Medicus
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4. Full Text My child has watering from above his left eye
by Wadhwani, Meenakshi and Manika, Manika
Oman journal of ophthalmology, ISSN 0974-620X, 9/2020, Volume 13, Issue 3, pp. 171 - 172
lacrimal | fistula | aberrant
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5. Full Text Chemopreventive effect of zingerone against colon carcinogenesis induced by 1,2-dimethylhydrazine in rats
by Vinothkumar, Rajenderan and Vinothkumar, Rajamanickam and Sudha, Mani and Nalini, Namasivayam
European journal of cancer prevention, ISSN 0959-8278, 2014, Volume 23, Issue 5, pp. 361 - 371
aberrant crypt foci | zingerone | lipid peroxidation | 1,2-dimethylhydrazine | Life Sciences & Biomedicine | Oncology | Science & Technology | Public health. Hygiene-occupational medicine | Public health. Hygiene | Miscellaneous | Prevention and actions | Biological and medical sciences | Multiple tumors. Solid tumors. Tumors in childhood (general aspects) | Medical sciences | Tumors | Aberrant Crypt Foci - chemically induced | Rats, Wistar | Colonic Neoplasms - prevention & control | Antioxidants - metabolism | Carcinogenesis - chemically induced | Rats | 1,2-Dimethylhydrazine - toxicity | Colonic Neoplasms - chemically induced | Male | Aberrant Crypt Foci - pathology | Carcinogens - toxicity | Carcinogenesis - drug effects | Carcinogenesis - pathology | Animals | Guaiacol - therapeutic use | Colonic Neoplasms - pathology | Guaiacol - analogs & derivatives | Lipid Peroxidation - drug effects | Oxidative Stress - drug effects | Aberrant Crypt Foci - prevention & control | Anticarcinogenic Agents - therapeutic use | Index Medicus
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6. Full Text Structural shift of gut microbiota during chemo-preventive effects of epigallocatechin gallate on colorectal carcinogenesis in mice
by Wang, Xin and Ye, Tao and Chen, Wen-Jie and Lv, You and Hao, Zong and Chen, Jun and Zhao, Jia-Ying and Wang, Hui-Peng and Cai, Yuan-Kun
World journal of gastroenterology : WJG, ISSN 1007-9327, 12/2017, Volume 23, Issue 46, pp. 8128 - 8139
Gastroenterology & Hepatology | Life Sciences & Biomedicine | Science & Technology | Rectum - pathology | Humans | Colon - drug effects | Azoxymethane - toxicity | Carcinogens - toxicity | Rectum - drug effects | RNA, Ribosomal, 16S - isolation & purification | Catechin - therapeutic use | Female | Catechin - pharmacology | Anticarcinogenic Agents - pharmacology | Aberrant Crypt Foci - prevention & control | Disease Models, Animal | Rectum - microbiology | Aberrant Crypt Foci - chemically induced | Colon - pathology | Aberrant Crypt Foci - microbiology | Colorectal Neoplasms - prevention & control | Colorectal Neoplasms - microbiology | Aberrant Crypt Foci - pathology | Gastrointestinal Microbiome - genetics | Colorectal Neoplasms - chemically induced | Dextran Sulfate - toxicity | Carcinogenesis - drug effects | Animals | Gastrointestinal Microbiome - drug effects | RNA, Ribosomal, 16S - genetics | Catechin - analogs & derivatives | Colon - microbiology | Mice | Colorectal Neoplasms - pathology | Index Medicus | Gut microbiota | Epigallocatechin gallate | Animal experiment | High throughput sequencing | Chemoprevention | Colorectal cancer | Basic Study
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7. Full Text Metformin suppresses colorectal aberrant crypt foci in a short-term clinical trial
by Hosono, Kunihiro and Endo, Hiroki and Takahashi, Hirokazu and Sugiyama, Michiko and Sakai, Eiji and Uchiyama, Takashi and Suzuki, Kaori and Iida, Hiroshi and Sakamoto, Yasunari and Yoneda, Kyoko and Koide, Tomoko and Tokoro, Chikako and Abe, Yasunobu and Inamori, Masahiko and Nakagama, Hitoshi and Nakajima, Atsushi
Cancer prevention research (Philadelphia, Pa.), ISSN 1940-6207, 09/2010, Volume 3, Issue 9, pp. 1077 - 1083
Life Sciences & Biomedicine | Oncology | Science & Technology | Metformin - therapeutic use | Rectum - pathology | Humans | Middle Aged | Adenoma - prevention & control | Male | Antineoplastic Agents - therapeutic use | Rectum - drug effects | Time Factors | Insulin Resistance - physiology | Lipids - blood | Female | Antineoplastic Agents - pharmacology | Aberrant Crypt Foci - prevention & control | Hypoglycemic Agents - therapeutic use | Colorectal Neoplasms - blood | Metformin - pharmacology | Aberrant Crypt Foci - blood | Colorectal Neoplasms - prevention & control | Aberrant Crypt Foci - pathology | Hypoglycemic Agents - pharmacology | Adenoma - blood | Pilot Projects | Adenoma - pathology | Aged | Cell Proliferation - drug effects | Clinical Trials as Topic - methods | Colorectal Neoplasms - pathology | Index Medicus
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8. Full Text Colon epithelial proliferation and carcinogenesis in diet‐induced obesity
by Takahashi, Hirokazu and Hosono, Kunihiro and Endo, Hiroki and Nakajima, Atsushi
Journal of gastroenterology and hepatology, ISSN 0815-9319, 12/2013, Volume 28, Issue 4, pp. 41 - 47
aberrant crypt foci | adiponectin | AMPK | colorectal carcinogenesis | metformin | Colorectal carcinogenesis | Metformin | Aberrant crypt foci | Adiponectin | Aberrant Crypt Foci - etiology | Cell Proliferation | Metformin - therapeutic use | Sirolimus | Humans | Diet, High-Fat - adverse effects | Adiponectin - physiology | Colorectal Neoplasms - etiology | Aberrant Crypt Foci - prevention & control | Disease Models, Animal | Hypoglycemic Agents - therapeutic use | Colon - pathology | Colorectal Neoplasms - blood | Risk Factors | Aberrant Crypt Foci - blood | Colorectal Neoplasms - prevention & control | Epithelial Cells - pathology | Aberrant Crypt Foci - pathology | Adiponectin - blood | Obesity, Abdominal - etiology | Obesity, Abdominal - pathology | AMP-Activated Protein Kinases - physiology | Obesity, Abdominal - blood | Animals | Cell Transformation, Neoplastic | Signal Transduction - physiology | Mice | Colorectal Neoplasms - pathology | Obesity | Colon cancer | Analysis | Body weight | Diabetes | Carcinogenesis | Index Medicus
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9. Full Text The modulatory effects of exercise on the inflammatory and apoptotic markers in rats with 1,2-dimethylhydrazine-induced colorectal cancer
by Ghazizadeh Darband, Saber and Saboory, Ehsan and Sadighparvar, Shirin and Kaviani, Mojtaba and Mobaraki, Kazhal and Jabbari, Nasrollah and Majidinia, Maryam
Canadian journal of physiology and pharmacology, ISSN 0008-4212, 2020, Volume 98, Issue 3, pp. 147 - 155
colorectal cancer | PCNA | ACF | COX-2 | exercice physique | dimethylhydrazine | diméthylhydrazine | exercise | apoptosis | apoptose | cancer colorectal | foyers de cryptes aberrantes | Pharmacology & Pharmacy | Physiology | Life Sciences & Biomedicine | Science & Technology | Aberrant Crypt Foci - chemically induced | Inflammation - pathology | Aberrant Crypt Foci - therapy | Rats, Wistar | Rats | 1,2-Dimethylhydrazine - toxicity | Male | Aberrant Crypt Foci - pathology | Colorectal Neoplasms - chemically induced | Inflammation - etiology | Apoptosis Regulatory Proteins - metabolism | Carcinogens - toxicity | Aberrant Crypt Foci - metabolism | Colorectal Neoplasms - therapy | Inflammation - metabolism | Animals | Inflammation Mediators - metabolism | Inflammation - prevention & control | Colorectal Neoplasms - pathology | Colorectal Neoplasms - metabolism | Physical Conditioning, Animal | Apoptosis | Ethylenediaminetetraacetic acid | Tumor necrosis factor | Oncology, Experimental | Colorectal cancer | Inflammation | Research | Cancer | Bax protein | Bcl-2 protein | Colorectal carcinoma | 1,2-Dimethylhydrazine | Tumor necrosis factor-α | Caspase-3 | Serum levels | Interleukin 6 | Colon cancer | Proliferating cell nuclear antigen | Tumorigenesis | Cyclooxygenase-2 | Colon | Index Medicus
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10. Full Text Oral 5-fluorouracil colon-specific delivery through in vivo pellet coating for colon cancer and aberrant crypt foci treatment
by Bose, A and Elyagoby, A and Wong, T.W
International journal of pharmaceutics, ISSN 0378-5173, 07/2014, Volume 468, Issue 1-2, pp. 178 - 186
Colon-specific drug delivery | Colon cancer | 5-Fluorouracil | In vivo pellet coating | Life Sciences & Biomedicine | Pharmacology & Pharmacy | Science & Technology | Adenocarcinoma - pathology | Antimetabolites, Antineoplastic - pharmacokinetics | Adenocarcinoma - chemically induced | Colonic Neoplasms - drug therapy | Biological Availability | Colonic Neoplasms - chemically induced | Colonic Neoplasms - metabolism | Adenoma - metabolism | Antimetabolites, Antineoplastic - administration & dosage | Drug Delivery Systems | Feasibility Studies | Cellulose - chemistry | Adenocarcinoma - metabolism | Antimetabolites, Antineoplastic - blood | Fluorouracil - administration & dosage | Fluorouracil - blood | Adenoma - drug therapy | Female | Cellulose - analogs & derivatives | Aberrant Crypt Foci - drug therapy | Aberrant Crypt Foci - chemically induced | Powders | Administration, Oral | Solubility | Technology, Pharmaceutical - methods | Aberrant Crypt Foci - pathology | Antimetabolites, Antineoplastic - chemistry | Adenocarcinoma - drug therapy | Rats, Sprague-Dawley | Chemistry, Pharmaceutical | Pectins - chemistry | Aberrant Crypt Foci - metabolism | Dimethylhydrazines | Animals | Tumor Burden - drug effects | Fluorouracil - chemistry | Colonic Neoplasms - pathology | Adenoma - pathology | Fluorouracil - pharmacokinetics | Tablets, Enteric-Coated | Adenoma - chemically induced | Coatings | Fluorouracil | Index Medicus
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11. Full Text Genistein, a soya isoflavone, prevents azoxymethane-induced up-regulation of WNT/β-catenin signalling and reduces colon pre-neoplasia in rats
by Zhang, Yukun and Li, Qian and Zhou, Dan and Chen, Hong
British journal of nutrition, ISSN 0007-1145, 01/2013, Volume 109, Issue 1, pp. 33 - 42
Full Papers | Molecular Nutrition | Colon cancer | Aberrant crypt foci | Soya genistein | WNT signalling | Life Sciences & Biomedicine | Nutrition & Dietetics | Science & Technology | Fundamental and applied biological sciences. Psychology | Feeding. Feeding behavior | Biological and medical sciences | Vertebrates: anatomy and physiology, studies on body, several organs or systems | Cyclin D1 - metabolism | Maternal Nutritional Physiological Phenomena | Lactation | Colonic Neoplasms - prevention & control | Male | Precancerous Conditions - metabolism | Colonic Neoplasms - metabolism | Carcinogens | Azoxymethane | Colon, Descending - metabolism | Genistein - metabolism | Female | Genistein - therapeutic use | Precancerous Conditions - pathology | Wnt Signaling Pathway | Aberrant Crypt Foci - prevention & control | Disease Models, Animal | Biomarkers - metabolism | Soybean Proteins - metabolism | Down-Regulation | Rats | Aberrant Crypt Foci - pathology | Proto-Oncogene Proteins c-myc - metabolism | Rats, Sprague-Dawley | Aberrant Crypt Foci - metabolism | Pregnancy | Animals | Colon, Descending - pathology | Cyclin D1 - genetics | Colonic Neoplasms - pathology | Soybean Proteins - therapeutic use | Proto-Oncogene Proteins c-myc - genetics | Precancerous Conditions - prevention & control | Index Medicus
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12. Full Text Pan-Cancer Landscape of Aberrant DNA Methylation across Human Tumors
by Saghafinia, Sadegh and Mina, Marco and Riggi, Nicolo and Hanahan, Douglas and Ciriello, Giovanni
Cell reports (Cambridge), ISSN 2211-1247, 10/2018, Volume 25, Issue 4, pp. 1066 - 1080.e8
TCGA pan-cancer cohort | DNA methylation instability | cancer epigenetics | aberrant DNA methylation | pediatric cancer | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Index Medicus
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