Articles

Search Articles

Advanced search
Help

Catalogue

Articles

Databases

X
Search Filters
Format Format
Format Format
X
Sort by Item Count (A-Z)
Filter by Count
Journal Article (11925) 11925
Book Review (1943) 1943
Publication (994) 994
Book Chapter (157) 157
Dissertation (70) 70
Conference Proceeding (54) 54
Book / eBook (9) 9
Magazine Article (8) 8
Government Document (3) 3
Paper (2) 2
Trade Publication Article (1) 1
Web Resource (1) 1
more...
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
index medicus (8525) 8525
humans (6910) 6910
male (3837) 3837
female (3593) 3593
animals (2662) 2662
oncology (2553) 2553
aberrant crypt foci (2348) 2348
cancer (1913) 1913
adult (1730) 1730
middle aged (1693) 1693
dna methylation (1654) 1654
aged (1267) 1267
rats (1105) 1105
aberrant methylation (1077) 1077
chromosome aberrations (1059) 1059
mice (1023) 1023
methylation (990) 990
aberrant expression (900) 900
expression (883) 883
research (863) 863
biochemistry & molecular biology (862) 862
colorectal-cancer (848) 848
chromosome disorders (788) 788
analysis (773) 773
colorectal cancer (773) 773
child (710) 710
cell biology (697) 697
carcinogenesis (692) 692
adolescent (678) 678
gene expression (677) 677
genetic aspects (660) 660
tumors (657) 657
prognosis (652) 652
pathology (643) 643
mutation (631) 631
colon cancer (624) 624
apoptosis (617) 617
genetics & heredity (584) 584
gene expression regulation, neoplastic (568) 568
genes (551) 551
article (540) 540
immunohistochemistry (535) 535
aged, 80 and over (530) 530
surgery (529) 529
epigenetics (528) 528
karyotyping (524) 524
aberrant dna methylation (520) 520
cell line, tumor (516) 516
risk factors (510) 510
aberrant promoter methylation (506) 506
colonic neoplasms - chemically induced (504) 504
azoxymethane (501) 501
gastroenterology & hepatology (497) 497
child, preschool (485) 485
colonic neoplasms - pathology (465) 465
health aspects (462) 462
colonic neoplasms - prevention & control (454) 454
diagnosis (449) 449
proteins (448) 448
promoter regions, genetic (445) 445
epigenesis, genetic (443) 443
gene-expression (431) 431
care and treatment (423) 423
hypermethylation (423) 423
dna (410) 410
development and progression (403) 403
polymerase chain reaction (401) 401
breast-cancer (392) 392
chemoprevention (391) 391
gene (385) 385
infant (384) 384
medicine, research & experimental (375) 375
colon (366) 366
colon-cancer (365) 365
rats, inbred f344 (364) 364
carcinoma (362) 362
pregnancy (362) 362
cpg islands (361) 361
abridged index medicus (360) 360
medicine & public health (360) 360
pharmacology & pharmacy (357) 357
phenotype (354) 354
cells (348) 348
children (347) 347
colon - pathology (344) 344
toxicology (344) 344
neurosciences (342) 342
carcinogens (335) 335
biomarkers (329) 329
nutrition & dietetics (328) 328
prevention (325) 325
rodents (324) 324
hematology (323) 323
diet (322) 322
risk (321) 321
infant, newborn (320) 320
aberrant behavior (309) 309
young adult (307) 307
reverse transcriptase polymerase chain reaction (303) 303
disease models, animal (302) 302
more...
Library Location Library Location
Language Language
Language Language
X
Sort by Item Count (A-Z)
Filter by Count
English (10138) 10138
French (1577) 1577
Japanese (135) 135
Spanish (87) 87
German (75) 75
Korean (42) 42
Chinese (38) 38
Portuguese (25) 25
Russian (16) 16
Polish (13) 13
Italian (8) 8
Czech (6) 6
Turkish (4) 4
Slovenian (3) 3
Hungarian (2) 2
Slovak (2) 2
Belarusian (1) 1
Croatian (1) 1
Dutch (1) 1
Lithuanian (1) 1
Serbian (1) 1
more...
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


1. Full Text Glycyrrhizic Acid Suppresses the Development of Precancerous Lesions via Regulating the Hyperproliferation, Inflammation, Angiogenesis and Apoptosis in the Colon of Wistar Rats
by Khan, Rehan and Khan, Abdul Quaiyoom and Lateef, Abdul and Rehman, Muneeb U and Tahir, Mir and Ali, Farrah and Hamiza, Oday O and Sultana, Sarwat
PLoS ONE, ISSN 1932-6203, 02/2013, Volume 8, Issue 2, pp. e56020 - e56020
Background: Colon carcinogenesis is a multistep process and it emanates from a series of molecular and histopathological alterations. Glycyrrhizic acid (GA) is... 
K-RAS MUTATIONS | OXIDATIVE STRESS | MULTIDISCIPLINARY SCIENCES | CHRONIC HEPATITIS-C | MAST-CELLS | PROLIFERATIVE ACTIVITY | PRENEOPLASTIC LESIONS | NF-KAPPA-B | ABERRANT CRYPT FOCI | MUCIN-DEPLETED FOCI | PROMYELOTIC LEUKEMIA | Rats, Wistar | Apoptosis - drug effects | Colon - drug effects | Colon - immunology | Male | Aberrant Crypt Foci - immunology | Mucins - analysis | Tumor Necrosis Factor-alpha - immunology | Anti-Inflammatory Agents - therapeutic use | Sialomucins - analysis | Aberrant Crypt Foci - prevention & control | Anticarcinogenic Agents - therapeutic use | Connexin 43 - analysis | Aberrant Crypt Foci - chemically induced | Mast Cells - immunology | Colon - pathology | Colorectal Neoplasms - prevention & control | Rats | Aberrant Crypt Foci - pathology | Connexin 43 - immunology | Colorectal Neoplasms - chemically induced | Mast Cells - drug effects | Tumor Necrosis Factor-alpha - analysis | Dimethylhydrazines | Glycyrrhizic Acid - therapeutic use | Animals | Colorectal Neoplasms - immunology | Mast Cells - pathology | Cell Proliferation - drug effects | Colorectal Neoplasms - pathology | Prevention | Antiviral agents | Colon cancer | Oncology, Experimental | Inflammation | Research | Tumor proteins | Vascular endothelial growth factor | Cancer | Apoptosis | Biological properties | p53 Protein | Colorectal cancer | Connexin 43 | Caspase-3 | Carcinogenesis | Angiogenesis | Carcinogens | Toxicology | Rodents | Tumor necrosis factor-TNF | Colon | Supplementation | Lesions | NF-κB protein | Cytokines | Cyclin-dependent kinases | Caspase | Pharmacology | Tumor necrosis factor-α | Nitric-oxide synthase | Mucin | Acids | Natural products | Caspase-9 | Mast cells | Infiltration | Mutation | Cyclooxygenase-2 | Aberration | Tumors | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
2. Full Text Protective effect of metformin in an aberrant crypt foci model induced by 1,2‐dimethylhydrazine: Modulation of oxidative stress and inflammatory process
by Bordini, Heloíza Paranzini and Kremer, Jean Lucas and Fagundes, Tatiane Renata and Melo, Gabriella Pasqual and Conchon‐Costa, Ivete and da Silva, Suelen Santos and Cecchini, Alessandra Lourenço and Panis, Carolina and Luiz, Rodrigo Cabral
Molecular Carcinogenesis, ISSN 0899-1987, 03/2017, Volume 56, Issue 3, pp. 913 - 922
Colorectal Cancer (CRC) is the third most frequent type of cancer worldwide. In the past few years, studies have revealed a protective effect of metformin... 
aberrant crypt foci | metformin | colorectal cancer | 1,2‐dimethylhydrazine | prevention | 1,2-dimethylhydrazine | ACTIVATION | ACID | APOPTOTIC CELL-DEATH | BIOCHEMISTRY & MOLECULAR BIOLOGY | COLON CARCINOGENESIS | PROLIFERATION | CANCER | ONCOLOGY | NITRIC-OXIDE | EXPRESSION | Aberrant Crypt Foci - chemically induced | AMP-Activated Protein Kinases - metabolism | Metformin - pharmacology | Colorectal Neoplasms - prevention & control | 1,2-Dimethylhydrazine - toxicity | Treatment Outcome | Aberrant Crypt Foci - immunology | Colorectal Neoplasms - chemically induced | Aberrant Crypt Foci - metabolism | Animals | Colorectal Neoplasms - immunology | Signal Transduction - drug effects | Neoplasms, Experimental | Female | Cell Proliferation - drug effects | Mice | Metformin - administration & dosage | Oxidative Stress - drug effects | Colorectal Neoplasms - metabolism | Aberrant Crypt Foci - prevention & control | Oxidative stress | Analysis | Hypoglycemic agents | Pharmacology | Nitric oxide | Colorectal cancer | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
3. Full Text Pomegranate polyphenolics suppressed azoxymethane-induced colorectal aberrant crypt foci and inflammation: Possible role of miR-126/VCAM-1 and miR-126/PI3K/ AKT/mTOR
by Banerjee, Nivedita and Kim, Hyemee and Talcott, Stephen and Mertens-Talcott, Susanne
Carcinogenesis, ISSN 0143-3334, 12/2013, Volume 34, Issue 12, pp. 2814 - 2822
The antitumorigenic activities of polyphenols such as ellagitannins and anthocyanins in pomegranate (Punica granatum L.) have been previously studied where... 
COLON-CANCER CELLS | IN-VITRO | CARCINOGENESIS | ONCOLOGY | HIGH-FAT DIET | CHEMOPREVENTIVE ACTIVITIES | PROSTATE-CANCER | GROWTH | FACTOR-KAPPA-B | JUICE | EXTRACT | Inflammation - chemically induced | TOR Serine-Threonine Kinases - metabolism | Colorectal Neoplasms - genetics | Humans | Polyphenols - pharmacology | Male | MicroRNAs - metabolism | Azoxymethane - adverse effects | Proto-Oncogene Proteins c-akt - genetics | Aberrant Crypt Foci - genetics | Inflammation - metabolism | TOR Serine-Threonine Kinases - genetics | Cyclooxygenase 2 - genetics | Inflammation - drug therapy | Vascular Cell Adhesion Molecule-1 - genetics | Punicaceae | Beverages | Proto-Oncogene Proteins c-akt - metabolism | Anticarcinogenic Agents - pharmacology | Phosphatidylinositol 3-Kinase - metabolism | Colorectal Neoplasms - metabolism | Aberrant Crypt Foci - drug therapy | Aberrant Crypt Foci - chemically induced | Rats | Colorectal Neoplasms - chemically induced | Rats, Sprague-Dawley | Aberrant Crypt Foci - metabolism | HT29 Cells | Animals | Nitric Oxide Synthase Type II - genetics | Phosphatidylinositol 3-Kinase - genetics | Cyclooxygenase 2 - metabolism | Cell Line, Tumor | Inflammation - genetics | Cell Proliferation - drug effects | Colorectal Neoplasms - diet therapy | MicroRNAs - genetics | Vascular Cell Adhesion Molecule-1 - metabolism | Nitric Oxide Synthase Type II - metabolism | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
4. Full Text Chemopreventive evaluation of a schiff base derived copper (II) complex against azoxymethane-induced colorectal cancer in rats
by Hajrezaie, Maryam and Hassandarvish, Pouya and Moghadamtousi, Soheil Zorofchian and Gwaram, Nura Suleiman and Golbabapour, Shahram and NajiHussien, Abdrabuh and Almagrami, Amel Abdullah and Zahedifard, Maryam and Rouhollahi, Elham and Karimian, Hamed and Fani, Somaye and Kamalidehghan, Behnam and Majid, Nazia Abdul and Ali, Hapipah Mohd and Abdulla, Mahmood Ameen
PLoS ONE, ISSN 1932-6203, 03/2014, Volume 9, Issue 3, pp. e91246 - e91246
Background: Based on the potential of Schiff base compounds to act as sources for the development of cancer chemotherapeutic agents, this in vivo study was... 
COLON-CANCER | APOPTOSIS | CELLS | OXIDATIVE STRESS | CARCINOGENESIS | MULTIDISCIPLINARY SCIENCES | COMPOUND | PROLIFERATION | INDUCTION | PROTEASOME INHIBITORS | ABERRANT CRYPT FOCI | Blood Chemical Analysis | Body Weight - drug effects | Male | Toxicity Tests, Acute | Azoxymethane - adverse effects | Schiff Bases - pharmacology | Carcinogens | Kidney - metabolism | Copper - chemistry | Liver - drug effects | Colorectal Neoplasms - drug therapy | Female | Colorectal Neoplasms - metabolism | Disease Models, Animal | Aberrant Crypt Foci - drug therapy | Aberrant Crypt Foci - chemically induced | Kidney - drug effects | Oxidation-Reduction | Chemoprevention | Liver - metabolism | Rats | Aberrant Crypt Foci - pathology | Colorectal Neoplasms - chemically induced | Aberrant Crypt Foci - metabolism | Animals | Schiff Bases - chemistry | Colorectal Neoplasms - pathology | Proliferating Cell Nuclear Antigen - metabolism | Prevention | Immunohistochemistry | Schiff bases | Chemotherapy | Colorectal cancer | Copper compounds | Cancer | Bax protein | 5-Fluorouracil | Colorectal carcinoma | Superoxide dismutase | PCNA protein | Colon cancer | Azoxymethane | Catalase | Imines | Proliferating cell nuclear antigen | Peroxidase | Colon | Copper | Coordination compounds | Glutathione | Glutathione peroxidase | Dysplasia | Superoxide | Malondialdehyde | In vivo methods and tests | Cyclooxygenase-2 | Aberration | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
5. Full Text Diet-Induced Obesity Promotes Colon Tumor Development in Azoxymethane-Treated Mice
by Tuominen, Iina and Al-Rabadi, Leina and Stavrakis, Dimitris and Karagiannides, Iordanis and Pothoulakis, Charalabos and Bugni, James M
PLoS ONE, ISSN 1932-6203, 04/2013, Volume 8, Issue 4, pp. e60939 - e60939
Obesity is an important risk factor for colon cancer in humans, and numerous studies have shown that a high fat diet enhances colon cancer development. As both... 
COLORECTAL CARCINOGENESIS | KK-A(Y) MICE | INFLAMMATION | MULTIDISCIPLINARY SCIENCES | SUSCEPTIBILITY | FAT | RATS | BODY-MASS INDEX | CANCER | TUMORIGENESIS | ABERRANT CRYPT FOCI | Obesity - immunology | Aberrant Crypt Foci - complications | Adenoma - immunology | Colon - immunology | Colonic Neoplasms - chemically induced | Male | Aberrant Crypt Foci - immunology | Adenoma - complications | Azoxymethane | Colonic Neoplasms - immunology | Diet, High-Fat | Tumor Necrosis Factor-alpha - immunology | Aberrant Crypt Foci - chemically induced | Colon - pathology | Obesity - complications | Mice, Inbred C57BL | Risk Factors | Interleukin-1beta - immunology | Aberrant Crypt Foci - pathology | Colonic Neoplasms - complications | Obesity - pathology | Animals | Colonic Neoplasms - pathology | Interferon-gamma - immunology | Interleukin-6 - immunology | Adenoma - pathology | Mice | Adenoma - chemically induced | Obesity | Development and progression | Colon cancer | Research | Risk factors | Tumors | Adipose tissue | Interleukin | High fat diet | Interleukin 6 | Carcinogens | Developmental stages | Rodents | Tumor necrosis factor-TNF | Tumorigenesis | Colon | Lesions | Cytokines | Health risks | Inflammation | Group dynamics | Tumor necrosis factor-α | Insulin resistance | Interferon | Aberration | Cancer | Apoptosis | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
6. Full Text Effect of Spirogyra neglecta on the early stages of 1, 2-dimethylhydrazine-induced colon carcinogenesis in rats
by Taya, Sirinya and Thumvijit, Tarika and Chewonarin, Teera and Punvittayagul, Charatda and Wongpoomchai, Rawiwan
European Journal of Cancer Prevention, ISSN 0959-8278, 2018, Volume 27, Issue 2, pp. 110 - 117
This study focused on the chemopreventive effects of Spirogyra neglecta extract (SNE) and dried S. neglecta mixed diet on the early stages of... 
aberrant crypt foci | apoptosis | colorectal carcinogenesis | Spirogyra neglecta | cell proliferation | xenobiotic metabolizing enzyme | INTESTINAL CARCINOGENESIS | GALACTAN | CELL-PROLIFERATION | ABERRANT CRYPTS | ANTITUMOR | AZOXYMETHANE | GREEN-ALGA | ONCOLOGY | BLACK TEA | POLYSACCHARIDES | CRYPT FOCI FORMATION | Rats, Wistar | Apoptosis - drug effects | Colonic Neoplasms - prevention & control | Plant Extracts - pharmacology | Humans | Colon - drug effects | Colonic Neoplasms - chemically induced | Male | Neoplasms, Experimental - chemically induced | Carcinogens - toxicity | Anticarcinogenic Agents - pharmacology | Aberrant Crypt Foci - prevention & control | Anticarcinogenic Agents - therapeutic use | Aberrant Crypt Foci - chemically induced | Colon - pathology | Neoplasms, Experimental - prevention & control | Rats | 1,2-Dimethylhydrazine - toxicity | Treatment Outcome | Aberrant Crypt Foci - pathology | Aryl Hydrocarbon Hydroxylases - metabolism | Animals | Spirogyra - chemistry | Colonic Neoplasms - pathology | Cell Proliferation - drug effects | Neoplasm Staging | Plant Extracts - therapeutic use | Colon cancer | Diet therapy | Oncology, Experimental | Green algae | Models | Chemical properties | Research | Health aspects | Carcinogenesis | Cancer | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
7. Full Text Toll-Like Receptor 2 signaling protects mice from tumor development in a mouse model of Colitis-induced cancer
by Lowe, Emily L and Crother, Timothy R and Rabizadeh, Shervin and Hu, Bing and Wang, Hanlin and Chen, Shuang and Shimada, Kenichi and Wong, Michelle H and Michelsen, Kathrin S and Arditi, Moshe
PLoS ONE, ISSN 1932-6203, 2010, Volume 5, Issue 9, pp. e13027 - e13027
Inflammatory bowel disease (IBD) is a disorder of chronic inflammation with increased susceptibility to colorectal cancer. The etiology of IBD is unclear but... 
INFLAMMATORY-BOWEL-DISEASE | TGF-BETA | DENDRITIC CELLS | EPITHELIAL-CELLS | NITRIC-OXIDE SYNTHASE | COLORECTAL-CANCER | IN-VIVO | BIOLOGY | REGULATORY T-CELLS | SPONTANEOUS INTESTINAL TUMORIGENESIS | CUTTING EDGE | Aberrant Crypt Foci - etiology | Toll-Like Receptor 2 - genetics | Colitis - genetics | Humans | Colitis - complications | Male | Aberrant Crypt Foci - immunology | Colorectal Neoplasms - etiology | Female | Colitis - immunology | Aberrant Crypt Foci - prevention & control | Disease Models, Animal | Signal Transduction | Mice, Inbred C57BL | Colorectal Neoplasms - prevention & control | Aberrant Crypt Foci - pathology | Immunity, Innate | Mice, Knockout | Neoplastic Processes | Animals | Colorectal Neoplasms - immunology | Interleukin-6 - immunology | Toll-Like Receptor 2 - immunology | Mice | Colorectal Neoplasms - pathology | Gastrointestinal diseases | Oncology, Experimental | Colorectal cancer | Colitis | Research | Risk factors | Cancer | Diseases | Immunohistochemistry | Haplotypes | Pediatrics | Inflammatory bowel diseases | Epithelial cells | Physicians | Colorectal carcinoma | Homeostasis | Innate immunity | Genomes | Immunity | Interleukin 6 | Proteins | Microorganisms | Histopathology | Immunology | Lymphocytes | Etiology | Intestine | Rodents | Toll-like receptors | Bacteria | Tumorigenesis | Medical research | Immune response | Cytokines | Stat3 protein | Inflammation | Epithelium | Crohns disease | Immune systems | Medicine | Inflammatory bowel disease | Signaling | Infectious diseases | TLR2 protein | Regulation | Aberration | Immunofluorescence | Tumors | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
8. Full Text Chemopreventive effect of Callistemon citrinus (Curtis) Skeels against colon cancer induced by 1,2-dimethylhydrazine in rats
by López-Mejia, Alejandro and Ortega-Pérez, Luis Gerardo and Godinez-Hernández, Daniel and Nateras-Marin, Blanca and Meléndez-Herrera, Esperanza and Rios-Chavez, Patricia
Journal of Cancer Research and Clinical Oncology, ISSN 0171-5216, 6/2019, Volume 145, Issue 6, pp. 1417 - 1426
Callistemon citrinus (Curtis) Skeels is a shrub native of Australia. In spite of containing an important number of bioactive compounds (1,8-cineole, limonene... 
Colon cancer | Medicine & Public Health | Hematology | Chemoprevention | Glutathione S -transferase | Oncology | Cancer Research | Internal Medicine | 1,2-Dimethylhydrazine | Quinone reductase | CURCUMIN | EGCG | PROLIFERATION | INDUCTION | AZOXYMETHANE | CARCINOGENESIS | ONCOLOGY | D-LIMONENE | POLYPHENOL | GLUTATHIONE-S-TRANSFERASE | Glutathione S-transferase | ABERRANT CRYPT FOCI | Aberrant Crypt Foci - drug therapy | Aberrant Crypt Foci - chemically induced | Rats, Wistar | Colonic Neoplasms - prevention & control | Plant Extracts - pharmacology | Body Weight - drug effects | Rats | Colonic Neoplasms - chemically induced | Male | Aberrant Crypt Foci - pathology | Random Allocation | Myrtaceae - chemistry | Carcinogens | Animals | Colonic Neoplasms - pathology | Colonic Neoplasms - enzymology | Antineoplastic Agents, Phytogenic - pharmacology | Disease Models, Animal
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
9. Full Text A novel myokine, secreted protein acidic and rich in cysteine (SPARC), suppresses colon tumorigenesis via regular exercise
by Aoi, Wataru and Naito, Yuji and Takagi, Tomohisa and Tanimura, Yuko and Takanami, Yoshikazu and Kawai, Yukari and Sakuma, Kunihiro and Hang, Liu Po and Mizushima, Katsura and Hirai, Yasuko and Koyama, Ryota and Wada, Sayori and Higashi, Akane and Kokura, Satoshi and Ichikawa, Hiroshi and Yoshikawa, Toshikazu
Gut, ISSN 0017-5749, 06/2013, Volume 62, Issue 6, pp. 882 - 889
Objective Several epidemiological studies have shown that regular exercise can prevent the onset of colon cancer, although the underlying mechanism is unclear.... 
PROMOTER HYPERMETHYLATION | ENDOCRINE ORGAN | APOPTOSIS | CELLS | THERAPY | COLORECTAL CANCERS | RISK | PHYSICAL-ACTIVITY | GASTROENTEROLOGY & HEPATOLOGY | EXPRESSION | HUMAN SKELETAL-MUSCLE | Tumor Suppressor Proteins - metabolism | Oligonucleotide Array Sequence Analysis | Colonic Neoplasms - prevention & control | Humans | Glycoproteins - metabolism | Male | Muscle Fibers, Skeletal - metabolism | Physical Conditioning, Animal - physiology | Cell Transformation, Neoplastic - metabolism | Colonic Neoplasms - metabolism | Mice, Inbred ICR | Mice, Knockout | Aberrant Crypt Foci - metabolism | Colonic Neoplasms - physiopathology | Animals | Osteonectin | Aberrant Crypt Foci - physiopathology | Exercise - physiology | Mice | Apoptosis - physiology | Tumor Cells, Cultured | Aberrant Crypt Foci - prevention & control | Prevention | Colon cancer | Exercise | Physiological aspects | Tumor suppressor genes | Research | Muscle proteins | Health aspects | Review boards | Colorectal cancer | Cardiovascular disease | Metabolism | Experiments | Variance analysis | Epidemiology | Studies | Proteins | Musculoskeletal system | Physical fitness | Rodents | Tumorigenesis | Diabetes | Apoptosis | Index Medicus | Abridged Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
10. Full Text Metformin suppresses colorectal aberrant crypt foci in a short-term clinical trial
by Hosono, Kunihiro and Endo, Hiroki and Takahashi, Hirokazu and Sugiyama, Michiko and Sakai, Eiji and Uchiyama, Takashi and Suzuki, Kaori and Iida, Hiroshi and Sakamoto, Yasunari and Yoneda, Kyoko and Koide, Tomoko and Tokoro, Chikako and Abe, Yasunobu and Inamori, Masahiko and Nakagama, Hitoshi and Nakajima, Atsushi
Cancer Prevention Research, ISSN 1940-6207, 09/2010, Volume 3, Issue 9, pp. 1077 - 1083
The biguanide metformin is widely used for treating diabetes mellitus. We previously showed the chemopreventive effect of metformin in two rodent models of... 
COLON-CANCER | HOMEOSTASIS | ONCOLOGY | GLUCOSE | IN-VIVO | KINASE | GROWTH | PREVENTION | RISK | CARCINOMA | MTOR | Metformin - therapeutic use | Rectum - pathology | Humans | Middle Aged | Adenoma - prevention & control | Male | Antineoplastic Agents - therapeutic use | Rectum - drug effects | Time Factors | Insulin Resistance - physiology | Lipids - blood | Female | Antineoplastic Agents - pharmacology | Aberrant Crypt Foci - prevention & control | Hypoglycemic Agents - therapeutic use | Colorectal Neoplasms - blood | Metformin - pharmacology | Aberrant Crypt Foci - blood | Colorectal Neoplasms - prevention & control | Aberrant Crypt Foci - pathology | Hypoglycemic Agents - pharmacology | Adenoma - blood | Pilot Projects | Adenoma - pathology | Aged | Cell Proliferation - drug effects | Clinical Trials as Topic - methods | Colorectal Neoplasms - pathology | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
11. Full Text Chemopreventive effect of zingerone against colon carcinogenesis induced by 1,2-dimethylhydrazine in rats
by Vinothkumar, Rajenderan and Vinothkumar, Rajamanickam and Sudha, Mani and Nalini, Namasivayam
European Journal of Cancer Prevention, ISSN 0959-8278, 2014, Volume 23, Issue 5, pp. 361 - 371
Zingerone [4-(4-hydroxy-3-methoxyphenyl)-2-butane], one of the active phenolic components isolated from Zingiber officinale, has antioxidant and... 
aberrant crypt foci | zingerone | lipid peroxidation | 1,2-dimethylhydrazine | OXIDATIVE STRESS | ASSAY | ACID | LIPID-PEROXIDATION | PATHOGENESIS | ANIMAL-TISSUES | ONCOLOGY | COLORECTAL-CANCER | ANTIOXIDANT | SUPEROXIDE-DISMUTASE | Aberrant Crypt Foci - chemically induced | Rats, Wistar | Colonic Neoplasms - prevention & control | Antioxidants - metabolism | Carcinogenesis - chemically induced | Rats | 1,2-Dimethylhydrazine - toxicity | Colonic Neoplasms - chemically induced | Male | Aberrant Crypt Foci - pathology | Carcinogens - toxicity | Carcinogenesis - drug effects | Carcinogenesis - pathology | Animals | Guaiacol - therapeutic use | Colonic Neoplasms - pathology | Guaiacol - analogs & derivatives | Lipid Peroxidation - drug effects | Oxidative Stress - drug effects | Aberrant Crypt Foci - prevention & control | Anticarcinogenic Agents - therapeutic use | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
12. Full Text Systematic identification of dysregulated lncRNAs associated with platinum-based chemotherapy response across 11 cancer types
by Zhu, Yanjiao and Zhao, Yichuan and Dong, Siyao and Liu, Lu and Tai, Lin and Xu, Yan
Genomics, ISSN 0888-7543, 07/2019
Aberrant expression of long non-coding RNAs (lncRNAs) leads to the development of chemoresistance by regulating a series of biological processes, which is one... 
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
13. Full Text Enhanced chemopreventive effects of a hydrogen sulfide-releasing anti-inflammatory drug (ATB-346) in experimental colorectal cancer
by Elsheikh, Wagdi and Blackler, Rory W and Flannigan, Kyle L and Wallace, John L
Nitric Oxide, ISSN 1089-8603, 09/2014, Volume 41, pp. 131 - 137
Regular use of nonsteroidal anti-inflammatory drugs is associated with a significantly lower incidence of several types of cancer, particularly those affecting... 
Prostaglandins | Cyclooxygenase | Colorectal | Chemoprevention | Nonsteroidal anti-inflammatory drug | Inflammation | Familial adenomatous polypoidosis | Cancer | BIOCHEMISTRY & MOLECULAR BIOLOGY | PREVENTION | ABERRANT CRYPTS | RAT MODEL | AZOXYMETHANE | CELL BIOLOGY | COLON-CANCER | IN-VITRO | MOUSE MODEL | INHIBITORS | CYCLOOXYGENASE 1 | Dinoprostone - analysis | Naproxen - analogs & derivatives | Thromboxane B2 - metabolism | Colon - drug effects | Naproxen - pharmacology | Male | Anti-Inflammatory Agents, Non-Steroidal - blood | Azoxymethane - toxicity | Anti-Inflammatory Agents, Non-Steroidal - pharmacology | Naproxen - pharmacokinetics | Protective Agents - pharmacology | Protective Agents - analysis | Colorectal Neoplasms - metabolism | Aberrant Crypt Foci - prevention & control | Aberrant Crypt Foci - chemically induced | Protective Agents - pharmacokinetics | Colorectal Neoplasms - prevention & control | Rats | Naproxen - blood | Colorectal Neoplasms - chemically induced | Colon - metabolism | Aberrant Crypt Foci - metabolism | Dinoprostone - metabolism | Animals | Anti-Inflammatory Agents, Non-Steroidal - pharmacokinetics | Mice | Thromboxane B2 - blood | Hydrogen sulfide | Prevention | Product enhancement | Anti-inflammatory drugs | Colorectal cancer | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights