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Journal Article
Lancet Oncology, The, ISSN 1470-2045, 2012, Volume 13, Issue 6, pp. 598 - 606
Journal Article
PLoS ONE, ISSN 1932-6203, 03/2015, Volume 10, Issue 3, p. e0121980
Lynch syndrome is caused by germline mutations of DNA mismatch repair (MMR) genes, most frequently MLH1 and MSH2. Recently, MMR-deficient crypt foci (MMR-DCF)... 
COLON CANCERS | HNPCC | EVOLUTION | HEREDITARY | NONPOLYPOSIS COLORECTAL-CANCER | MICROSATELLITE INSTABILITY | MULTIDISCIPLINARY SCIENCES | RISK | FRAMESHIFT MUTATIONS | TUMORS | GENETIC ALTERATIONS | MutL Protein Homolog 1 | Microsatellite Instability | Age Factors | Colorectal Neoplasms, Hereditary Nonpolyposis - genetics | Colorectal Neoplasms, Hereditary Nonpolyposis - pathology | Humans | Middle Aged | MutS Homolog 2 Protein - genetics | Aberrant Crypt Foci - pathology | DNA-Binding Proteins - genetics | Aberrant Crypt Foci - genetics | Proteins - genetics | Young Adult | Adaptor Proteins, Signal Transducing - genetics | Adult | Aged | Nuclear Proteins - genetics | bcl-2-Associated X Protein - genetics | Intestinal Mucosa - pathology | Immunohistochemistry | Gene mutations | Colorectal cancer | Transformation | Bax protein | Endometrial cancer | Genes | Mucosa | Colorectal carcinoma | Biology | Microsatellite instability | Inactivation | DNA repair | Proteins | Alterations | Intestine | Mismatch repair | Cooperation | Gastroenterology | Tumorigenesis | Lesions | Repair | Deoxyribonucleic acid--DNA | Medical research | Microsatellites | Stability | Deactivation | MLH1 protein | MSH2 protein | Patients | Molecular chains | Pathology | Crypts | Protein expression | Transformations | Mutation | Cancer | Deoxyribonucleic acid | DNA
Journal Article
BMC Cancer, ISSN 1471-2407, 02/2018, Volume 18, Issue 1, pp. 213 - 9
Background: Aberrant crypt foci (ACF) are commonly considered the early pre-cancerous lesions that can progress to colorectal cancer (CRC). The available... 
Dietary patterns | Adenoma | Aberrant crypt foci | Large intestine | RISK-FACTORS | QUANTIFICATION | IDENTIFICATION | MEAT | COLON-CANCER | OBESITY | ONCOLOGY | DISEASE | PHYSICAL-ACTIVITY | EPIDEMIOLOGY | Usage | Food habits | Colorectal cancer | Dietary supplements | Development and progression | Research | Health aspects | Risk factors
Journal Article
Carcinogenesis, ISSN 0143-3334, 12/2013, Volume 34, Issue 12, pp. 2814 - 2822
The antitumorigenic activities of polyphenols such as ellagitannins and anthocyanins in pomegranate (Punica granatum L.) have been previously studied where... 
COLON-CANCER CELLS | IN-VITRO | CARCINOGENESIS | ONCOLOGY | HIGH-FAT DIET | CHEMOPREVENTIVE ACTIVITIES | PROSTATE-CANCER | GROWTH | FACTOR-KAPPA-B | JUICE | EXTRACT | Inflammation - chemically induced | TOR Serine-Threonine Kinases - metabolism | Colorectal Neoplasms - genetics | Humans | Polyphenols - pharmacology | Male | MicroRNAs - metabolism | Azoxymethane - adverse effects | Proto-Oncogene Proteins c-akt - genetics | Aberrant Crypt Foci - genetics | Inflammation - metabolism | TOR Serine-Threonine Kinases - genetics | Cyclooxygenase 2 - genetics | Inflammation - drug therapy | Vascular Cell Adhesion Molecule-1 - genetics | Punicaceae | Beverages | Proto-Oncogene Proteins c-akt - metabolism | Anticarcinogenic Agents - pharmacology | Phosphatidylinositol 3-Kinase - metabolism | Colorectal Neoplasms - metabolism | Aberrant Crypt Foci - drug therapy | Aberrant Crypt Foci - chemically induced | Rats | Colorectal Neoplasms - chemically induced | Rats, Sprague-Dawley | Aberrant Crypt Foci - metabolism | HT29 Cells | Animals | Nitric Oxide Synthase Type II - genetics | Phosphatidylinositol 3-Kinase - genetics | Cyclooxygenase 2 - metabolism | Cell Line, Tumor | Inflammation - genetics | Cell Proliferation - drug effects | Colorectal Neoplasms - diet therapy | MicroRNAs - genetics | Vascular Cell Adhesion Molecule-1 - metabolism | Nitric Oxide Synthase Type II - metabolism
Journal Article
Journal of Ethnopharmacology, ISSN 0378-8741, 12/2016, Volume 193, pp. 195 - 206
Journal Article
Journal of Ethnopharmacology, ISSN 0378-8741, 02/2014, Volume 151, Issue 3, pp. 1194 - 1201
Journal Article
PLoS ONE, ISSN 1932-6203, 11/2014, Volume 9, Issue 11, pp. e111118 - e111118
Andrographis paniculata is a grass-shaped medicinal herb, traditionally used in Southeast Asia. The aim of this study was to evaluate the chemoprotective... 
5-FLUOROURACIL | OXIDATIVE STRESS | CARCINOGENESIS | COLORECTAL-CANCER | ANTIOXIDANT | MULTIDISCIPLINARY SCIENCES | TOTAL PHENOLIC CONTENT | PREVENTION | PLANTS | ABSORPTION | EXTRACT | Aberrant Crypt Foci - drug therapy | Malondialdehyde - metabolism | Aberrant Crypt Foci - chemically induced | Plant Extracts - chemistry | Antioxidants - metabolism | Humans | Colon - drug effects | Rats | Andrographis - chemistry | Rats, Sprague-Dawley | beta Catenin - metabolism | Azoxymethane - adverse effects | Tissue Distribution | Animals | Anticarcinogenic Agents - chemistry | Colorectal Neoplasms - drug therapy | Phenol - chemistry | Cell Line, Tumor | Female | Nitric Oxide - metabolism | Proliferating Cell Nuclear Antigen - metabolism | Flavonoids - chemistry | Superoxide Dismutase - metabolism | Prevention | Colon cancer | Nitric oxide | Cancer | Oxidative stress | Mucosa | Colorectal carcinoma | Glands | Colorectal cancer | Science | Superoxide dismutase | Kinases | Cancer therapies | Antioxidants | β-catenin | Chinese medicine | Azoxymethane | Rodents | Orifices | Proliferating cell nuclear antigen | Colon | Elongation | Medical research | Ethanol | Malondialdehyde | Inflammatory bowel disease | Herbal medicine | Nutrition research | Chemotherapy | Natural products | Cell lines | Aberration | Tumors | Index Medicus | Medicinal Chemistry | Basic Medicine | Medical and Health Sciences | Medicin och hälsovetenskap | Läkemedelskemi | Medicinska och farmaceutiska grundvetenskaper
Journal Article
BioMed Research International, ISSN 2314-6133, 2017, Volume 2017, pp. 3634915 - 8
2,3,5,4'-Tetrahydroxystilbene-2-O-beta-D-glucoside (THSG) has been shown to have antioxidative and anti-inflammatory effects. Oxidative and inflammatory... 
MEDICINE, RESEARCH & EXPERIMENTAL | ANGIOGENESIS | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | COLON | CARCINOEMBRYONIC ANTIGEN | NF-KAPPA-B | EXPRESSION | CARCINOMA | EXTRACT | Aberrant Crypt Foci - drug therapy | Aberrant Crypt Foci - chemically induced | Stilbenes - administration & dosage | Colorectal Neoplasms - genetics | Humans | Carcinoembryonic Antigen - genetics | Rats | Aberrant Crypt Foci - pathology | Azoxymethane - toxicity | Colorectal Neoplasms - chemically induced | Intestinal Mucosa - drug effects | Carcinogens - toxicity | Aberrant Crypt Foci - genetics | Animals | Glucosides - administration & dosage | NF-kappa B - genetics | Anticarcinogenic Agents - administration & dosage | Cyclooxygenase 2 - genetics | Colorectal Neoplasms - drug therapy | Gene Expression Regulation, Neoplastic - drug effects | Colorectal Neoplasms - pathology | Disease Models, Animal | Intestinal Mucosa - pathology | Health sciences | Colorectal carcinoma | Colorectal cancer | Matrix metalloproteinase | Kinases | Carcinogenesis | Prostaglandin endoperoxide synthase | Antioxidants | Proteins | Carcinoembryonic antigen | Carcinogens | Azoxymethane | Rodents | Animal tissues | Metalloproteinase | Colon | NF-κB protein | Antigens | Inflammation | Dentistry | Hospitals | Medical prognosis | Cyclooxygenase-2 | Aberration | Laboratory animals | Nuclear reactions | Cancer
Journal Article