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Asian Pacific Journal of Cancer Prevention, ISSN 1513-7368, 2013, Volume 14, Issue 10, pp. 5849 - 5854
Background: Apoptosis may be induced after Bcl-2 expression is inhibited in proliferative cancer cells. This study focused on the effect of autophagy... 
Bcl-2 | Chemotherapy | ABT737 | Autophagy | SURVIVAL | HEPATOCELLULAR-CARCINOMA | autophagy | MECHANISM | BECLIN-1 | ONCOLOGY | PATHWAY | ATG16L1 | MONODANSYLCADAVERINE | chemotherapy
Journal Article
Life Sciences, ISSN 0024-3205, 09/2019, Volume 232, p. 116561
Journal Article
Nanotechnology, ISSN 0957-4484, 10/2017, Volume 28, Issue 46, p. 465102
Although activating apoptosis in cancer cells by targeting the mitochondria is an effective strategy for cancer therapy, insufficient targeting of the... 
non-small cell lung cancer | ABT737 | mitochondria | anticancer efficacy | APOPTOSIS | PHYSICS, APPLIED | ARTHRITIS SYNOVIAL FIBROBLASTS | BH3 MIMETICS | DRUG-DELIVERY | MATERIALS SCIENCE, MULTIDISCIPLINARY | ABT-737 | NANOSCIENCE & NANOTECHNOLOGY | DEATH | TUMORS | THERAPY | PATHWAY | BCL-2 FAMILY
Journal Article
International Journal of Oncology, ISSN 1019-6439, 12/2016, Volume 49, Issue 6, pp. 2507 - 2519
Journal Article
Oncogene, ISSN 0950-9232, 09/2011, Volume 30, Issue 37, pp. 3918 - 3929
The BH3 mimetic ABT737 induces autophagy by competitively disrupting the inhibitory interaction between the BH3 domain of Beclin 1 and the anti-apoptotic... 
autophagy | ABT737 | Bcl-2 family protein | Beclin 1 | CELLS | COMPLEX | BIOCHEMISTRY & MOLECULAR BIOLOGY | IKK | INDUCTION | CELL BIOLOGY | ONCOLOGY | GENETICS & HEREDITY | BCL-2 FAMILY | BH3-ONLY PROTEINS | Phosphorylation | Nitriles - pharmacology | Ribosomal Protein S6 Kinases - metabolism | TOR Serine-Threonine Kinases - metabolism | Humans | Autophagy - drug effects | Biphenyl Compounds - pharmacology | I-kappa B Kinase - metabolism | Nitrophenols - pharmacology | Phosphotransferases (Phosphate Group Acceptor) - metabolism | Benzopyrans - pharmacology | Oncogene Protein v-akt - metabolism | Proto-Oncogene Proteins c-mdm2 - metabolism | Beclin-1 | Tumor Suppressor Protein p53 - metabolism | Glycogen Synthase Kinase 3 - metabolism | Sulfonamides - pharmacology | Membrane Proteins - agonists | Piperazines - pharmacology | Signal Transduction - drug effects | Apoptosis Regulatory Proteins - agonists | Cell Line, Tumor | Proto-Oncogene Proteins c-bcl-2 - antagonists & inhibitors | Sirtuins - metabolism | Acetyl-CoA Carboxylase - metabolism | Autophagy (Cytology) | Cellular proteins | Care and treatment | Physiological aspects | Genetic aspects | Cellular signal transduction | Research | Cancer | Proteins | Signal transduction | Biomimetics | Cellular biology | Gene expression | Sirtuins | TOR protein | MDM2 protein | Bcl-2 protein | Glycogen synthase kinase 3 | AKT protein | Dephosphorylation | IKK protein | p53 protein | Allosteric properties | NF- Kappa B protein | Bcl-x protein | I Kappa B kinase | Lipid kinase | Phagocytosis | Ubiquitin-protein ligase
Journal Article
Journal Article
Journal Article
Cell Death and Disease, ISSN 2041-4889, 01/2012, Volume 3, Issue 1, pp. e262 - e262
Sorafenib, a multi-tyrosine kinase inhibitor, kills more effectively the non-metastatic prostate cancer cell line 22Rv1 than the highly metastatic prostate... 
ABT737 | Tyrosine kinase inhibitor | Autophagy | Prostate cancer | Sorafenib | Apoptosis | TRANSFORMATION | ACTIVATION | autophagy | sorafenib | apoptosis | PHASE-II | FISH ANALYSIS | RAF/MEK/ERK PATHWAY | CELL BIOLOGY | BCL-2 | prostate cancer | RECEPTOR TYROSINE KINASES | tyrosine kinase inhibitor | PROGNOSTIC-SIGNIFICANCE | EXPRESSION | Niacinamide - analogs & derivatives | Carcinoma | Cell Proliferation | Apoptosis - drug effects | Coculture Techniques | Humans | Male | Phenylurea Compounds | Molecular Targeted Therapy | Proto-Oncogene Proteins c-akt - genetics | Antineoplastic Combined Chemotherapy Protocols - pharmacology | Proto-Oncogene Proteins c-bcl-2 - metabolism | Benzenesulfonates - pharmacology | Prostatic Neoplasms - genetics | Gene Expression Regulation, Neoplastic - drug effects | Phosphorylation - drug effects | Proto-Oncogene Proteins c-akt - metabolism | Prostatic Neoplasms - drug therapy | Fibroblasts - metabolism | Prostatic Neoplasms - pathology | Signal Transduction - genetics | Signal Transduction - drug effects | Myeloid Cell Leukemia Sequence 1 Protein | Proto-Oncogene Proteins pp60(c-src) - genetics | Proto-Oncogene Proteins pp60(c-src) - metabolism | Cell Line, Tumor | Proto-Oncogene Proteins c-bcl-2 - antagonists & inhibitors | Fibroblasts - cytology | Protein Kinase Inhibitors - pharmacology | Pyridines - pharmacology | Primary Cell Culture | Prostate | Proto-Oncogene Proteins c-bcl-2 - genetics | Drug Resistance, Neoplasm - drug effects | Original
Journal Article
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