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PloS one, ISSN 1932-6203, 2016, Volume 11, Issue 2, p. e0149733
Journal Article
Journal Article
PloS one, ISSN 1932-6203, 2018, Volume 13, Issue 5, p. e0197247
The alpha 7 nicotinic acetylcholine receptor ( nAChR) is a ligand-gated ion channel that plays an important role in cellular calcium signaling contributing to... 
CELLS | ACETYLCHOLINE-RECEPTORS | ACH RECEPTORS | PROTEIN | SPECTRIN | MULTIDISCIPLINARY SCIENCES | FILOPODIA | OUTGROWTH | GUIDANCE | SYNAPTIC PLASTICITY | HIPPOCAMPAL-NEURONS | Calpain - metabolism | Calcium - metabolism | Microtubule-Associated Proteins - metabolism | Rats | Ryanodine Receptor Calcium Release Channel - metabolism | alpha7 Nicotinic Acetylcholine Receptor - antagonists & inhibitors | Neurites - metabolism | PC12 Cells | Animals | Growth Cones - metabolism | Inositol 1,4,5-Trisphosphate Receptors - metabolism | Neurogenesis - physiology | Neurotransmitter Agents - pharmacology | Inositol 1,4,5-Trisphosphate Receptors - antagonists & inhibitors | Cytoskeleton - metabolism | Neurogenesis - drug effects | alpha7 Nicotinic Acetylcholine Receptor - metabolism | Growth Cones - drug effects | Spectrin - metabolism | Calpain - antagonists & inhibitors | Cytoskeleton - drug effects | Neurites - drug effects | Calpain | Drug compounding | Research | Nicotinic receptors | Analysis | Spectrin | Ryanodine | Motility | Calcium | Synaptogenesis | Developmental plasticity | Activation | Kinases | Calcium signalling | Proteins | Receptors | Proteolysis | Rodents | Penicillin | Synaptic plasticity | Breakdown | Attenuation | Ion channels | Inositol 1,4,5-trisphosphate | Growth cones | Calcium channels (ligand-gated) | Enzymes | Cones | Microscopy | Pheochromocytoma cells | Cytoskeleton | Ligands | Acetylcholine receptors (nicotinic) | Plastic foam
Journal Article
PloS one, ISSN 1932-6203, 2016, Volume 11, Issue 7, p. e0159996
The development of alpha7 nicotinic acetylcholine receptor agonists is considered a promising approach for the treatment of cognitive symptoms in schizophrenia... 
ACETYLCHOLINE-RECEPTORS | HUMAN BRAIN | TROPISETRON | MULTIDISCIPLINARY SCIENCES | IN-VIVO | RATS | EVP-6124 | DEFICITS | BINDING | PREFRONTAL CORTEX | PROOF-OF-CONCEPT | Cognition Disorders - physiopathology | Humans | Quinuclidines - pharmacology | Rats | Male | Spiro Compounds - therapeutic use | alpha7 Nicotinic Acetylcholine Receptor - agonists | Cognition Disorders - drug therapy | Patch-Clamp Techniques | Animals | Quinuclidines - therapeutic use | Schizophrenia - physiopathology | HEK293 Cells | Mice | Radioligand Assay | Schizophrenia - drug therapy | Drug Evaluation, Preclinical | Spiro Compounds - pharmacology | Complications and side effects | Attentional bias | Care and treatment | Analysis | Schizophrenia | Research | Neurophysiology | Neonates | Animal models | Serotonin S3 receptors | Calcium | Mental disorders | Memory | Cognitive ability | Fluorescence | Electrophysiology | Clinical trials | Oxazol | Cognition | Biology | Extradimensional shift | MK-801 | Auditory discrimination | Receptors | Phencyclidine | Mismatch negativity | Sensory integration | Rodents | Chief executive officers | Binding | Dopamine | Channel gating | Calcium channels (voltage-gated) | Pattern recognition | Object recognition | Generic drugs | Ketamine | Cognition & reasoning | Information processing | Acetylcholine receptors (nicotinic)
Journal Article
PloS one, ISSN 1932-6203, 05/2016, Volume 11, Issue 5, p. e0156451
Cigarette smoking is the major risk factor for non-small cell lung cancer (NSCLC), which accounts for 80% of all lung cancers. Nicotine, the addictive... 
TARGET GENES | ACTIVATION | INVASION | METASTASIS | PROMOTES TUMOR-GROWTH | CANCER CELLS | MULTIDISCIPLINARY SCIENCES | PROLIFERATION | SMOKING | SUSCEPTIBILITY LOCUS | MICROARRAY DATA | Smoking - adverse effects | Adenocarcinoma - pathology | Cyclin-Dependent Kinase 4 - genetics | Humans | Lung Neoplasms - metabolism | Lung Neoplasms - pathology | Neoplasm Proteins - metabolism | Nicotine - pharmacology | STAT1 Transcription Factor - metabolism | Adenocarcinoma - metabolism | Adenocarcinoma - genetics | Gene Expression Regulation, Neoplastic - drug effects | Neoplasm Proteins - genetics | Carcinoma, Non-Small-Cell Lung - pathology | Lung Neoplasms - genetics | A549 Cells | Carcinoma, Non-Small-Cell Lung - genetics | Carcinoma, Non-Small-Cell Lung - metabolism | Cyclin-Dependent Kinase 6 - genetics | alpha7 Nicotinic Acetylcholine Receptor - genetics | Smoking - genetics | Cyclin-Dependent Kinase 6 - metabolism | E2F1 Transcription Factor - metabolism | Cyclin-Dependent Kinase 4 - metabolism | STAT1 Transcription Factor - genetics | Smoking - metabolism | E2F1 Transcription Factor - genetics | alpha7 Nicotinic Acetylcholine Receptor - biosynthesis | Transcription factors | Receptors | Genetic aspects | Acetylcholine | Research | Lung cancer, Non-small cell | Health aspects | Nicotine | Adenocarcinoma | Mesenchyme | Lung cancer | Colorectal cancer | Raf protein | Genomes | Biology | Smoke | Metastasis | Kinases | Drug resistance | Cyclin-dependent kinase 4 | Risk factors | Metastases | Proteins | Angiogenesis | Cell cycle | DNA methylation | Stat1 protein | Deoxyribonucleic acid--DNA | Tobacco smoke | Cell survival | Health risks | Non-small cell lung carcinoma | Breast cancer | Gene expression | Cigarette smoking | Cigarettes | E2F1 protein | 1-Phosphatidylinositol 3-kinase | Tobacco | Ligands | Acetylcholine receptors (nicotinic) | Mutation | Cell migration | Smoking | Apoptosis | Tumors | Deoxyribonucleic acid | DNA
Journal Article