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61. Full Text Antiproliferative Constituents in Plants 14. Coumarins and Acridone Alkaloids from Boenninghausenia japonica NAKAI
by Chaya, Norihito and Terauchi, Kazuko and Yamagata, Yuriko and Kinjo, Junei and Okabe, Hikaru
Biological and Pharmaceutical Bulletin, ISSN 0918-6158, 2004, Volume 27, Issue 8, pp. 1312 - 1316
The MeOH extracts of the ground part and the root of Boenninghausenia japonica NAKAI showed inhibitory activity against tumor cell growth. Fractionation of the... 
acridone alkaloid | Boenninghausenia japonica | coumarin | antiproliferative activity | Antiproliferative activity | Coumarin | Acridone alkaloid | ALBIFLORA | ROOTS | PHARMACOLOGY & PHARMACY | Acridines - isolation & purification | Alkaloids - pharmacology | Acridones | Humans | Alkaloids - isolation & purification | Coumarins - pharmacology | Coumarins - isolation & purification | Animals | Acridines - pharmacology | Cell Line, Tumor | Cell Proliferation - drug effects | Mice | Plants - chemistry
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62. Denitrogenative Suzuki and carbonylative Suzuki coupling reactions of benzotriazoles with boronic acids
by Wang, Yuanhao and Wu, Yunfei and Li, Yuanhe and Tang, Yefeng
Chemical Science, ISSN 2041-6520, 05/2017, Volume 8, Issue 5, pp. 3852 - 3857
Unprecedented palladium-catalyzed denitrogenative Suzuki and carbonylative Suzuki coupling reactions of benzotriazoles with boronic acids have been realized,... 
Equivalence | Ketones | Chemical reactions | Strategy | Derivatives | Ring opening | Benzotriazoles | Carbonyls
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63. Full Text An I-2-mediated cascade reaction of 2 '-bromoacetophenones with benzohydrazides/benzamides leading to quinazolino[3,2-b]cinnoline or tryptanthrin derivatives
by Guo, SH and Zhai, JH and Fan, XS
ORGANIC & BIOMOLECULAR CHEMISTRY, ISSN 1477-0520, 02/2017, Volume 15, Issue 6, pp. 1521 - 1529
An efficient and facile protocol for the synthesis of quinazolinone-fused tetracyclic compounds through an iodine-mediated one-pot cascade reaction of... 
INTRAMOLECULAR N-ARYLATION | IODINE-CATALYZED SYNTHESIS | ONE-POT SYNTHESIS | AQUEOUS AMMONIA | REGIOSELECTIVE SYNTHESIS | CHEMISTRY, ORGANIC | TANDEM REACTION | 2-FORMYLBENZOIC ACIDS | QUINAZOLINONE ALKALOIDS | ARYL METHYL KETONES | ACRIDONE ALKALOIDS
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64. A direct and vicinal functionalization of the 1-methyl-2-quinolone framework: 4-alkoxylation and 3-chlorination
by Hao, Feiyue and Asahara, Haruyasu and Nishiwaki, Nagatoshi
Organic & Biomolecular Chemistry, ISSN 1477-0520, 05/2016, Volume 14, Issue 22, pp. 5128 - 5135
Bis(functionalization), 4-alkoxylation and 3-chlorination, of the 1-methyl-2-quinolone framework was achieved under mild conditions by a sequential treatment... 
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65. Full Text A direct and vicinal functionalization of the 1-methyl-2-quinolone framework: 4-alkoxylation and 3-chlorination
by Hao, Feiyue and Asahara, Haruyasu and Nishiwaki, Nagatoshi
Organic and Biomolecular Chemistry, ISSN 1477-0520, 2016, Volume 14, Issue 22, pp. 5128 - 5135
Bis(functionalization), 4-alkoxylation and 3-chlorination, of the 1-methyl-2-quinolone framework was achieved under mild conditions by a sequential treatment... 
CROSS-COUPLING REACTIONS | CARBAZOLE | 3,4-DISUBSTITUTED QUINOLIN-2(1H)-ONES | CONSTRUCTION | QUINOLONES | CHEMISTRY, ORGANIC | QUINOLINE ALKALOIDS | DERIVATIVES | ACRIDONE ALKALOIDS | ARYLBORONIC ACIDS | CONSTITUENTS
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66. Full Text Cancer chemopreventive activity of acridone alkaloids on Epstein–Barr virus activation and two-stage mouse skin carcinogenesis
by Itoigawa, Masataka and Ito, Chihiro and Wu, Tian-Shung and Enjo, Fumio and Tokuda, Harukuni and Nishino, Hoyoku and Furukawa, Hiroshi
Cancer Letters, ISSN 0304-3835, 2003, Volume 193, Issue 2, pp. 133 - 138
Seventeen acridone alkaloids isolated from the Rutaceous plants were tested for their inhibitory activities against Epstein-Barr virus early antigen activation... 
Acridone alkaloids | Rutaceous plant | Epstein–Bar virus | Epstein-Bar virus | acridone alkaloids | CHEMICAL-CONSTITUENTS | ONCOLOGY | BRASILIENSIS | INVITRO | COUMARIN | XANTHONES | Tetradecanoylphorbol Acetate | Alkaloids - pharmacology | Herpesvirus 4, Human - genetics | Skin Neoplasms - drug therapy | Models, Chemical | Acridones | Mice, Inbred ICR | Skin Neoplasms - metabolism | Carcinogens | Animals | Skin Neoplasms - prevention & control | Time Factors | Acridines - pharmacology | Biological Assay | Female | Mice | Herpesvirus 4, Human - metabolism | Anticarcinogenic Agents - pharmacology | Studies | Values | Skin | Biological assays | Rodents | Cancer
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67. Full Text Acridone Alkaloids and Coumarins from the Stem Bark of Citropsis articulata (Rutaceae)
by Meva’a, Luc Mbaze and Songue, Jules Lobe and Wansi, Jean Duplex and Waffo, Alain François Kamdem and Dongo, Etienne and Mpondo, Théophile Ngando and Sewald, Norbert
Zeitschrift für Naturforschung B, ISSN 0932-0776, 04/2010, Volume 65, Issue 4, pp. 525 - 527
A new acridone alkaloid, citropsine A (1), and thirteen known compounds (2 - 14) were isolated from the MeOH extract of the stem bark of Citropsis articulata.... 
Coumarins | Acridone Alkaloids | Citropsis articulata | Rutaceae | Acridone alkaloids | CHEMISTRY, ORGANIC | CHEMISTRY, INORGANIC & NUCLEAR
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68. Acridine and acridone derivatives, anticancer properties and synthetic methods: Where are we now?
by Belmont, Philippe and Bosson, Johann and Godet, Thomas and Tiano, Martin
Anti-Cancer Agents in Medicinal Chemistry, ISSN 1871-5206, 03/2007, Volume 7, Issue 2, pp. 139 - 169
Acridine derivatives are interesting chemotherapeutic agents that were first used as antibacterial and antiparasite agents. In this review we wish to... 
Organic synthesis | Acridine | Alkaloid | Topoisomerases | Antitumour | Hypoxia | Anticancer | Telomerase | Acridone | ONCOLOGY | CHEMISTRY, MEDICINAL | Protein Kinase Inhibitors - chemical synthesis | Alkaloids - pharmacology | Antineoplastic Agents - chemical synthesis | Humans | Enzyme Inhibitors - pharmacology | Topoisomerase I Inhibitors | Alkaloids - chemical synthesis | Biological Products - pharmacology | Enzyme Inhibitors - chemical synthesis | DNA, Neoplasm - drug effects | Acridines - chemical synthesis | Biological Products - chemistry | Animals | Acridines - pharmacology | Hypoxia - physiopathology | Antineoplastic Agents - pharmacology | Protein Kinase Inhibitors - pharmacology | Telomerase - antagonists & inhibitors
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69. Full Text Phytochemistry and pharmacognosy of the genus Acronychia
by Epifano, Francesco and Fiorito, Serena and Genovese, Salvatore
Phytochemistry, ISSN 0031-9422, 11/2013, Volume 95, pp. 12 - 18
The genus (Rutaceae) comprise 44 species distributed in a wide geographical area of South-Eastern Asia. Most of the species of the genus have been used for... 
Acetophenones | Acronychia genus | Rutaceae | Furanocoumarins | Prenyloxy secondary metabolites | Acridone alkaloids | Biological activity | Quinoline alkaloids | 4'-GERANYLOXYFERULIC ACID | BIOCHEMISTRY & MOLECULAR BIOLOGY | BAUERI SCHOTT | CANCER CHEMOPREVENTIVE AGENT | PLANT SCIENCES | ANTITUMOR AGENTS | PEDUNCULATA L. MIQ | ACROVESTONE | ROOT BARK | DERIVATIVES | ALKALOIDS | CONSTITUENTS | Animals | Phytochemicals - therapeutic use | Pharmacognosy | Plant Extracts - pharmacology | Humans | Phytotherapy | Rutaceae - chemistry | Medicine, Traditional | Phytochemicals - pharmacology | Plant Extracts - therapeutic use | Phytochemistry
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70. Full Text Bioactive acridone alkaloids from Swinglea glutinosa
by Weniger, B and Um, B.-H and Valentin, A and Estrada, A and Lobstein, A and Anton, R and Maillé, M and Sauvain, M
Journal of Natural Products, ISSN 0163-3864, 2001, Volume 64, Issue 9, pp. 1221 - 1223
A new prenylated acridone alkaloid, 1,3,5-trihydroxy-2,8-bis(3-methylbut-2-enyl)-10-methyl-9-acridone (1), was isolated from the stembark of Swinglea.... 
CONTINUOUS CULTURE | CHEMISTRY, MEDICINAL | CHEMICAL-CONSTITUENTS | PLASMODIUM-FALCIPARUM | LINDL | ANTIMALARIAL ACTIVITY | PHARMACOLOGY & PHARMACY | INDOLE ALKALOIDS | CHEMISTRY, APPLIED | DERIVATIVES | PLANT SCIENCES | Acridines - isolation & purification | Humans | Alkaloids - isolation & purification | Erythrocytes | Male | Plasmodium falciparum - drug effects | Dose-Response Relationship, Drug | Chloroquine - pharmacology | Antimalarials - isolation & purification | Inhibitory Concentration 50 | Female | Molecular Structure | Plant Stems - chemistry | Rutaceae - chemistry | Nigeria | Acridines - chemistry | Colombia | Plants, Medicinal - chemistry | Alkaloids - pharmacology | Magnetic Resonance Spectroscopy | Antineoplastic Agents, Phytogenic - chemistry | Spectrophotometry, Ultraviolet | HeLa Cells - drug effects | Antimalarials - pharmacology | Drug Resistance, Microbial | Animals | Acridines - pharmacology | Fibroblasts - drug effects | Antimalarials - chemistry | Antineoplastic Agents, Phytogenic - pharmacology | In Vitro Techniques | Alkaloids - chemistry | Antineoplastic Agents, Phytogenic - isolation & purification | acridone alkaloids
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71. Full Text Stereoselective synthesis of natural product inspired carbohydrate fused pyrano[3,2-: C] quinolones as antiproliferative agents
by Kumari, Priti and Narayana, Chintam and Dubey, Shraddha and Gupta, Ashish and Sagar, Ram
Organic and Biomolecular Chemistry, ISSN 1477-0520, 2018, Volume 16, Issue 12, pp. 2049 - 2059
Pyrano[3,2-c]quinolone structural motifs are commonly found in natural products with diverse biological activities. As part of a research programme aimed at... 
ONE-POT SYNTHESIS | CATALYZED REACTIONS | FLINDERSINE | DRUG DISCOVERY | ZANTHOXYLUM SIMULANS | REGIOSELECTIVE SYNTHESIS | EFFICIENT SYNTHESIS | CHEMISTRY, ORGANIC | DERIVATIVES | ACRIDONE ALKALOIDS | PYRANOQUINOLINE ALKALOIDS | Carbohydrates | Liver cancer | Hepatocytes | Natural products | Liver | Breast cancer | Derivatives | Drug discovery | Chemical synthesis | Quinolones | Cancer
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72. Full Text A New Acridone Alkaloid from Micromelum integerrimum
by Xiao-Long YANGa and c and Zheng-Hong XIEb and Xian-Jun JIANGb and Yan-Bing HUANGb and Ji-Kai LIUa and bBioBioPha Co and cGraduate School of Chinese Academy of Sciences and aState Key Laboratory of Phytochemistry and Plant Resources in West China and Chinese Academy of Sciences and Kunming Institute of Botany and Ltd
Chemical & Pharmaceutical Bulletin, ISSN 0009-2363, 2009, Volume 57, Issue 7, pp. 734 - 735
A new acridone alkaloid, 1,3-dihydroxy-4-methoxy-10-methylacridone (1), was isolated from leaves of the plant Micromelum integerrimum, together with two known... 
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73. Full Text Efficient base-catalyzed 5-exo-dig cyclization of carbonyl groups on unactivated alkynyl-quinolines: An entry to versatile oxygenated heterocycles related to the furoquinoline alkaloids family
by Godet, T and Bosson, J and Belmont, P
SYNLETT, ISSN 0936-5214, 11/2005, Issue 18, pp. 2786 - 2790
An efficient 5-exo-dig cyclization was observed when TMS-protected alkynyl-quinolines bearing a carbonyl group were submitted to a mixture of an alcohol... 
1,3-dihydrofuro[3,4-b]quinoline | QUINAZOLINE | O-ALKYNYLBENZALDEHYDES | CHEMISTRY, ORGANIC | TRIPLE BOND | quinoline | ACRIDONE ALKALOIDS | ALCOHOLS | NUCLEOPHILES | BENZANNULATION | INTRAMOLECULAR CYCLIZATION | CYCLOISOMERIZATION | 5-exo-dig cyclization | base-catalyzed cyclization | DERIVATIVES
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74. Full Text Acceptorless Dehydrogenative Cyclization of o-Aminobenzyl Alcohols with Ketones to Quinolines in Water Catalyzed by Water Soluble Metal Ligand Bifunctional Catalyst [Cp(6,6 '-(OH)(2)bpy)(H2O)[OTf](2)
by Wang, RZ and Fan, HJ and Zhao, W and Li, F
ORGANIC LETTERS, ISSN 1523-7060, 08/2016, Volume 18, Issue 15, pp. 3558 - 3561
The strategy for acceptorless dehydrogenative cyclization of o-aminobenzyl alcohols with ketones to quinolines in water has been accomplished. In the presence... 
FUNCTIONAL BIPYRIDONATE LIGAND | NITROGEN-HETEROCYCLES | ONE-POT SYNTHESIS | ASTERISK-IR COMPLEX | ALPHA-ALKYLATION | CHEMISTRY, ORGANIC | IRIDIUM COMPLEX | POLYSUBSTITUTED QUINOLINES | 2-AMINOBENZYL ALCOHOL | ACRIDONE ALKALOIDS | N-HETEROCYCLES
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75. Full Text Synthesis of Benzimidazolo[2,3-b]quinazolinone Derivatives via a One-pot Multicomponent Reaction Promoted by a Chitosan-based Composite Magnetic Nanocatalyst
by Maleki, Ali and Aghaei, Morteza and Ghamari, Nakisa
Chemistry Letters, ISSN 0366-7022, 3/2015, Volume 44, Issue 3, pp. 259 - 261
A practical and green approach for the one-pot multicomponent synthesis of tetraheterocyclic benzimidazolo[2,3-b]quinazolinones has been described via the... 
NANOPARTICLES | QUINOLINE | CHEMISTRY | CATALYST | 3-COMPONENT | GREEN | CHEMISTRY, MULTIDISCIPLINARY | ACRIDONE ALKALOIDS | QUINAZOLINONE DERIVATIVES
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76. Full Text A new flavonoid from the leaves of Atalantia monophylla (L.) DC
by Posri, Priyapan and Suthiwong, Jittra and Takomthong, Pitchayakarn and Wongsa, Chatchawan and Chuenban, Chindawadee and Boonyarat, Chantana and Yenjai, Chavi
Natural Product Research, ISSN 1478-6419, 04/2019, Volume 33, Issue 8, pp. 1115 - 1121
A new flavonoid, atalantraflavone (1) as well as eight known compounds including atalantoflavone (2), racemoflavone (3),... 
acetylcholine esterase | antioxidant | Atalanta monophylla | flavonoid | CHEMISTRY, MEDICINAL | INHIBITION | CHEMISTRY, APPLIED | CYTOTOXICITY | ALKALOIDS | Plant Leaves - chemistry | Drug Evaluation, Preclinical - methods | Alkaloids - pharmacology | Antioxidants - chemistry | Magnetic Resonance Spectroscopy | Plant Extracts - pharmacology | Isoflavones - pharmacology | Cholinesterase Inhibitors - chemistry | Isoflavones - chemistry | Antioxidants - pharmacology | Acridones - chemistry | Cholinesterase Inhibitors - pharmacology | Acridones - pharmacology | Flavonoids - pharmacology | Molecular Structure | Rutaceae - chemistry | Flavonoids - chemistry | Alkaloids - chemistry | Antioxidants | Leaves | Flavonoids | Neurodegenerative diseases | Esterase | Scavenging | Acetylcholine | Inhibition | Alzheimers disease | Alzheimer's disease | Tacrine
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77. Full Text Oxidative Rearrangement Coupling Reaction for the Functionalization of Tetrahydro--carbolines with Aromatic Amines
by Ye, JX and Wu, JL and Lv, TT and Wu, GL and Gao, Y and Chen, HJ
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, ISSN 1433-7851, 11/2017, Volume 56, Issue 47, pp. 14968 - 14972
The observation of an unexpected oxidative rearrangement coupling reaction led to the development of a novel method for the efficient functionalization of... 
ORGANIC-CHEMISTRY | visible light | CARBON-HYDROGEN BONDS | C-H FUNCTIONALIZATION | RADICAL-ADDITION | oxidative functionalization | CHEMISTRY, MULTIDISCIPLINARY | ACRIDONE ALKALOIDS | singlet oxygen | DEHYDROGENATIVE FUNCTIONALIZATION | AEROBIC OXIDATIONS | SECONDARY-AMINES | rearrangement | tetrahydro--carbolines | SINGLET-OXYGEN | MOLECULAR-OXYGEN | Active oxygen | Alkaloids | Aromatic amines | Coupling (molecular) | Chemical bonds | Transformation | Singlet oxygen | Amines | Trifluoroacetic acid
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78. Full Text An efficient one-pot protocol for the solvent-free synthesis of novel quinoline-3-thiocarboxamide and 2,3-dihydroquinazolin-4(1H)-one derivatives
by Narra, Srikanth Reddy and Avula, Sreenivas and Kuchukulla, Ratnakar Reddy and Nanubolu, Jagadeesh B and Banda, Narsaiah and Yadla, Rambabu
Tetrahedron, ISSN 0040-4020, 08/2017, Volume 73, Issue 32, pp. 4730 - 4738
An efficient and straightforward synthesis of a series of novel poly-substituted quinoline-3-thiocarboxamides and... 
3-Oxo-N,3-diarylpropanethioamide | Indium (III) chloride | Solvent-free synthesis | 2,3-Dihydroquinazolin-4(1H)-one | Quinoline-3-thiocarboxamide | QUINAZOLINE | ANALOGS | CHEMISTRY, ORGANIC | ACRIDONE ALKALOIDS | BIOLOGICAL EVALUATION | QUINOLINE DERIVATIVES | AGENTS | VITRO ANTITUMOR-ACTIVITY | INHIBITORS | Quinoline | Indium | Alkaloids
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79. Full Text Citropremide and Citropridone: A New Ceramide and a New Acridone Alkaloid from the Stem Bark of Citropsis gabunensis
by Tsassi, Béatrice Valerie and Hussain, Hidayat and Geagni, Albertine and Dongo, Etienne and Ahmed, Ishtiaq and Riaz, Muhammad and Krohn, Karsten
Helvetica Chimica Acta, ISSN 0018-019X, 06/2011, Volume 94, Issue 6, pp. 1035 - 1040
The structure elucidation and complete 1H‐ and 13C‐NMR assignments are reported for two new compounds: the ceramide citropremide (1), and the acridone alkaloid... 
Ceramides | Alkaloids | Citropridone | Acridone alkaloids | Citropremide | Citropsis gabunensis | CHEMISTRY, MULTIDISCIPLINARY
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80. Larvicidal activity of acridone alkaloids from zanthoxylum leprieurii against the malaria vector anopheles Gambiae
by Matasyoh, Josphat C and Talontsi, Ferdinand M and Ngoumfo, Rostand M and Chepkorir, Regina
Natural Products Journal, ISSN 2210-3155, 2011, Volume 1, Issue 2, pp. 121 - 124
Larvicidal activity | Zanthoxylum leprieurii | Anopheles gambiae | Malaria | Acridone alkaloids
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