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Nature Genetics, ISSN 1061-4036, 12/2014, Volume 47, Issue 1, pp. 31 - 38
Cushing's disease is caused by corticotroph adenomas of the pituitary. To explore the molecular mechanisms of endocrine autonomy in these tumors, we performed... 
UBPY | ENDOSOMES | DOMAIN | PROTEIN | EPIDERMAL-GROWTH-FACTOR | GENETICS & HEREDITY | UBIQUITYLATION | DEGRADATION | RECEPTOR DOWN-REGULATION | ENDOCYTIC TRAFFICKING | PITUITARY-ADENOMAS | Adenoma - genetics | Humans | Neoplasm Proteins - physiology | Gene Expression Regulation, Neoplastic | Cercopithecus aethiops | Endosomal Sorting Complexes Required for Transport - genetics | Molecular Sequence Data | Pituitary Neoplasms - complications | ACTH-Secreting Pituitary Adenoma - complications | Pituitary ACTH Hypersecretion - genetics | ACTH-Secreting Pituitary Adenoma - genetics | Receptor, Epidermal Growth Factor - metabolism | Pituitary Neoplasms - secretion | Neoplasm Proteins - genetics | Pro-Opiomelanocortin - genetics | Amino Acid Sequence | ACTH-Secreting Pituitary Adenoma - metabolism | Pituitary Neoplasms - genetics | Ubiquitin Thiolesterase - physiology | Pituitary Neoplasms - metabolism | Ubiquitin Thiolesterase - genetics | 14-3-3 Proteins - metabolism | Adrenocorticotropic Hormone - secretion | Sequence Homology, Amino Acid | Exome - genetics | Sequence Alignment | Animals | Endopeptidases - genetics | ACTH-Secreting Pituitary Adenoma - secretion | Pro-Opiomelanocortin - biosynthesis | Mutation | COS Cells | Endosomal Sorting Complexes Required for Transport - physiology | Endopeptidases - physiology | Gene mutations | Cushing syndrome | Physiological aspects | Genetic aspects | Research | Ubiquitin-proteasome system | Health aspects | Risk factors | Pituitary gland | Kinases | Rodents | Genes | Tumors | Index Medicus
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 12/2011, Volume 121, Issue 12, pp. 4712 - 4721
Cushing disease is a condition in which the pituitary gland releases excessive adrenocorticotropic hormone (ACTH) as a result of an adenoma arising from the... 
NUCLEAR-LOCALIZATION | MEDICINE, RESEARCH & EXPERIMENTAL | DEPENDENT CUSHINGS-SYNDROME | GEFITINIB INDUCES APOPTOSIS | CYCLE INHIBITOR P27(KIP1) | EPIDERMAL-GROWTH-FACTOR | PROOPIOMELANOCORTIN GENE | CORTICOTROPH TUMORS | T-BOX FACTOR | FACTOR RECEPTOR | PROGNOSTIC VALUE | ACTH-Secreting Pituitary Adenoma - drug therapy | Neoplasm Transplantation | Humans | Cell Line, Tumor - drug effects | Molecular Targeted Therapy | Pituitary ACTH Hypersecretion - drug therapy | ACTH-Secreting Pituitary Adenoma - complications | Adenoma - enzymology | Adenoma - complications | Dog Diseases - drug therapy | Dog Diseases - etiology | Secretory Rate - drug effects | Adenoma - drug therapy | Corticosterone - blood | Gene Expression Regulation, Neoplastic - drug effects | Pro-Opiomelanocortin - genetics | Adenoma - veterinary | Promoter Regions, Genetic | Pituitary ACTH Hypersecretion - etiology | ACTH-Secreting Pituitary Adenoma - veterinary | Cell Line, Tumor - enzymology | Tumor Burden | Adrenocorticotropic Hormone - secretion | Pituitary ACTH Hypersecretion - blood | Adenoma - blood | Dog Diseases - blood | ACTH-Secreting Pituitary Adenoma - blood | Animals | Mice, Nude | Protein Kinase Inhibitors - therapeutic use | Quinazolines - therapeutic use | Dogs | Receptor, Epidermal Growth Factor - antagonists & inhibitors | Mice | Protein Kinase Inhibitors - pharmacology | ACTH-Secreting Pituitary Adenoma - enzymology | Pituitary ACTH Hypersecretion - veterinary | Quinazolines - pharmacology | Drug Screening Assays, Antitumor | Care and treatment | Pituitary gland tumors | ACTH | Drug targeting | Adenoma | Diagnosis | Research | Properties | Index Medicus | Abridged Index Medicus
Journal Article
Journal Article
World Neurosurgery, ISSN 1878-8750, 08/2017, Volume 104, pp. 1048.e1 - 1048.e7
Rathke cleft cysts (RCCs) and pituitary adenomas (PAs) are thought to have a common embryonic ancestry; however, PAs with a concomitant RCC inside the sella... 
Rathke cleft cyst | Ectopic pituitary adenoma | Clival invasion | Sphenoid sinus tumor | ACTH pituitary adenoma | SURGERY | RESECTION | HYPERPROLACTINEMIA | SELLA | GLAND | LESIONS | CLINICAL NEUROLOGY | Neoplasms, Multiple Primary - surgery | Sphenoid Sinus - pathology | Adenoma - surgery | Choristoma - diagnostic imaging | Paranasal Sinus Neoplasms - diagnostic imaging | Humans | Tomography, X-Ray Computed | ACTH-Secreting Pituitary Adenoma - diagnostic imaging | Neoplasms, Multiple Primary - diagnostic imaging | ACTH-Secreting Pituitary Adenoma - complications | Sphenoid Sinus - diagnostic imaging | Paranasal Sinus Neoplasms - surgery | Paranasal Sinus Diseases - diagnostic imaging | Adenoma - complications | ACTH-Secreting Pituitary Adenoma - surgery | Adenoma - diagnostic imaging | Choristoma - complications | Female | Paranasal Sinus Diseases - pathology | Paranasal Sinus Diseases - complications | Sphenoid Sinus - surgery | Choristoma - surgery | Central Nervous System Cysts - surgery | Central Nervous System Cysts - diagnostic imaging | Neoplasms, Multiple Primary - pathology | Paranasal Sinus Neoplasms - complications | Central Nervous System Cysts - pathology | Magnetic Resonance Imaging | Paranasal Sinus Neoplasms - pathology | Adenoma - pathology | Central Nervous System Cysts - complications | Paranasal Sinus Diseases - surgery | Aged | Choristoma - pathology | Pituitary Gland | ACTH-Secreting Pituitary Adenoma - pathology | ACTH | Pituitary gland tumors | Adenoma | Index Medicus
Journal Article
Journal Article
Journal Article
World Neurosurgery, ISSN 1878-8750, 2016, Volume 95, pp. 406 - 413
Background Transsphenoidal surgery (TSS) is the most common approach for the treatment of pituitary tumors. However, misdirection, vascular damage,... 
Neurosurgery | Navigation | Optic nerve | Magnetic resonance imaging | Segmentation | Pituitary tumor | Internal carotid artery | SURGERY | DIGITAL-SUBTRACTION-ANGIOGRAPHY | FRAMELESS STEREOTAXY | CLINICAL NEUROLOGY | RECOVERY | DECOMPRESSION | ADENOMAS | Pituitary Neoplasms - surgery | Neuroendoscopy - methods | Adenoma - surgery | Dermoid Cyst - diagnostic imaging | Prospective Studies | Pituitary ACTH Hypersecretion - diagnostic imaging | Humans | Middle Aged | Male | ACTH-Secreting Pituitary Adenoma - diagnostic imaging | Angiography, Digital Subtraction | ACTH-Secreting Pituitary Adenoma - complications | Growth Hormone-Secreting Pituitary Adenoma - surgery | Cranial Nerves - diagnostic imaging | Dermoid Cyst - surgery | ACTH-Secreting Pituitary Adenoma - surgery | Pituitary ACTH Hypersecretion - surgery | Adenoma - diagnostic imaging | Female | Arachnoid Cysts - diagnostic imaging | Arachnoid Cysts - surgery | Neuronavigation - methods | Growth Hormone-Secreting Pituitary Adenoma - diagnostic imaging | Pituitary ACTH Hypersecretion - etiology | Ultrasonography, Doppler | Surgery, Computer-Assisted - methods | Blood Vessels - diagnostic imaging | Postoperative Complications - epidemiology | Thyrotropin - secretion | Magnetic Resonance Imaging | Cerebral Angiography | Adenoma - secretion | Pituitary Neoplasms - diagnostic imaging | Surgery | Pituitary gland tumors | Index Medicus | MRI
Journal Article
Pediatrics, ISSN 0031-4005, 12/2015, Volume 136, Issue 6, pp. e1632 - e1636
Journal Article
Journal Article
Journal Article
Journal of Neurosurgery, ISSN 0022-3085, 01/2008, Volume 108, Issue 1, pp. 9 - 18
Journal Article
Clinical Endocrinology, ISSN 0300-0664, 02/2015, Volume 82, Issue 2, pp. 260 - 266
Journal Article