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actinomadura-luzonensis (27) 27
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Organic Letters, ISSN 1523-7060, 12/1999, Volume 1, Issue 13, pp. 2153 - 2156
A two-step approach for the diastereoselective synthesis of 4-carboxymethyl 5-alkyl/aryl oxazolidin-2-ones is described, which proceeds via the intermediate... 
BETA-AMINO ACIDS | ANTIBIOTICS | ASYMMETRIC-SYNTHESIS | VANCOMYCIN | BBM-928-A | RING-OPENING REACTIONS | ESTERS | CHEMISTRY, ORGANIC | ACTINOMADURA-LUZONENSIS | STEREOSELECTIVE SYNTHESIS
Journal Article
Synthesis, ISSN 0039-7881, 6/2007, Volume 2007, Issue 11, pp. 1677 - 1682
ABSTRACT A short and flexible route for the synthesis of 1,2-diisopropyl-3-methyl-(3S,4R,5R)-4,5-dihydroxyhexahydro-1,2,3-pyrid­azinetricarboxylate, from... 
paper | Piperazic acid | Dihydroxylation | Intramolecular cyclisation | α-hydrazination | L-proline | DEPSIPEPTIDE | ANTIBIOTICS | BBM-928-A | EFFICIENT SYNTHESIS | CHEMISTRY, ORGANIC | ALDEHYDES | intramolecular cyclisation | PHYSICOCHEMICAL PROPERTIES | STREPTOMYCES SP | ALPHA-AMINATION | AMINO-ACIDS | dihydroxylation | ACTINOMADURA-LUZONENSIS | alpha-hydrazination | piperazic acid
Journal Article
Tetrahedron Letters, ISSN 0040-4039, 1995, Volume 36, Issue 37, pp. 6595 - 6598
N-acetyl oxazolone derivatives of serine and threonine are readily converted into reactive acid chlorides that condense efficiently with various C-protected... 
CHEMISTRY, ORGANIC | BBM-928-A | ACTINOMADURA-LUZONENSIS
Journal Article
Journal of the American Chemical Society, ISSN 0002-7863, 02/1996, Volume 118, Issue 7, pp. 1629 - 1644
Full details of the total synthesis of the potent antitumor antibiotic (−)-sandramycin (1), a cyclic decadepsipeptide possessing a 2-fold axis of symmetry, is... 
DEOXYRIBONUCLEIC-ACID | CYCLOSPORINE-A | TRIOSTIN-A | MOLECULAR-STRUCTURE | TUMOR ANTIBIOTIC COMPLEX | AMINO-ACIDS | CHEMISTRY | BIFUNCTIONAL INTERCALATION | PEPTIDE-SYNTHESIS | QUINOXALINE ANTIBIOTICS | ACTINOMADURA-LUZONENSIS | Cyclic compounds | Research | Antineoplastic antibiotics
Journal Article
Tetrahedron Letters, ISSN 0040-4039, 1997, Volume 38, Issue 28, pp. 4947 - 4950
The abnormal reluctance of piperazic acids to undergo N-2 acylation seems to be due to an electronic effect, not a steric / conformational problem. A system... 
CHEMISTRY, ORGANIC | K EE CHEMISTRY, ORGANIC | ANTIBIOTICS | BBM-928-A | ACTINOMADURA-LUZONENSIS
Journal Article
Journal Article
Journal of the American Chemical Society, ISSN 0002-7863, 12/1999, Volume 121, Issue 49, pp. 11375 - 11383
Full details of the total syntheses of luzopeptin A−C and quinoxapeptin A−C, C 2-symmetric cyclic depsidecapeptides bearing two pendant heterocyclic... 
DEOXYRIBONUCLEIC-ACID | NOCARDIOIDES SP | TUMOR ANTIBIOTIC COMPLEX | REVERSE-TRANSCRIPTASE | BIFUNCTIONAL INTERCALATION | DNA-BINDING PROPERTIES | PROTECTING GROUPS | SANDRAMYCIN | UNUSUAL AMINO-ACID | ACTINOMADURA-LUZONENSIS | CHEMISTRY, MULTIDISCIPLINARY | Amides | Research | Peptides | Heterocyclic compounds | DNA
Journal Article
Angewandte Chemie International Edition, ISSN 1433-7851, 08/1999, Volume 38, Issue 16, pp. 2424 - 2426
Journal Article
Tetrahedron Letters, ISSN 0040-4039, 2000, Volume 41, Issue 3, pp. 289 - 292
Protected versions of (3 R,5 R)-5-hydroxypiperazic acid were synthesized enantioselectively in two novel ways. The first derives its chirality from D-glutamic... 
amination | annulation | lactonisation | amino acid derivatives | Lactonisation | Amino acid derivatives | Amination | Annulation | STREPTOMYCES-HYGROSCOPICUS | ASYMMETRIC-SYNTHESIS | HIMASTATIN | BBM-928-A | CHEMISTRY, ORGANIC | UNUSUAL AMINO-ACID | ACTINOMADURA-LUZONENSIS | DERIVATIVES
Journal Article
Angewandte Chemie International Edition, ISSN 1433-7851, 07/2000, Volume 39, Issue 14, pp. 2493 - 2495
The self‐assembly of the 32‐membered macrocycle of luzopeptin E2 (1) has been accomplished by cyclodimerization of a terminally unprotected pentapeptide... 
natural products | depsipeptides | total synthesis | macrocycles | antitumor agents | Depsipeptides | Antitumor agents | Macrocycles | Natural products | Total synthesis | ACID | BBM-928-A | REVERSE-TRANSCRIPTASE | INTERCALATION CHROMOPHORE | DNA-BINDING PROPERTIES | CHEMISTRY, MULTIDISCIPLINARY | KEY SANDRAMYCIN ANALOGS | A-C | INHIBITORS | ACTINOMADURA-LUZONENSIS | SYSTEMATIC EXAMINATION
Journal Article
The Journal of Organic Chemistry, ISSN 0022-3263, 04/1996, Volume 61, Issue 8, pp. 2582 - 2583
Journal Article
Journal of the American Chemical Society, ISSN 0002-7863, 01/1998, Volume 120, Issue 1, pp. 80 - 86
N-Acyl derivatives of piperazic acids display an unusual degree of conformational rigidity. As a consequence, α-N-coupling of a piperazic acid of given... 
DESIGN | ASYMMETRIC-SYNTHESIS | PROTEIN | PEPTIDES | BBM-928-A | AMINO | STEREOSELECTIVE AMINATION | ALPHA-HYDRAZINO ACIDS | 4-HELIX BUNDLE | ACTINOMADURA-LUZONENSIS | CHEMISTRY, MULTIDISCIPLINARY | Research | Peptides | Piperazine | Analysis | Conformational analysis
Journal Article
Synlett, ISSN 0936-5214, 1998, Issue 11, pp. 1279 - 1281
A stereocontrolled synthesis of (2R, 3R)-3-hydroxyproline 5 has been achieved in 33% overall yield from a prochiral beta-ketoester : the methyl... 
HYDROGENATION | ACID | BBM-928-A | CHEMISTRY, ORGANIC | electrophilic amination | trans-3-hydroxy-D-proline | ESTERS | hydrazine cleavage | anti-alpha-amino-beta-hydroxyester | ACTINOMADURA-LUZONENSIS | chiral ruthenium catalyst | CATALYSTS | ALKALOIDS
Journal Article
Tetrahedron Letters, ISSN 0040-4039, 1999, Volume 40, Issue 51, pp. 9045 - 9049
A rhodium complex coordinated with a trans-chelating chiral diphosphine (S,S)-(R,R)-PhTRAP was an effective catalyst for asymmetric hydrogenation of... 
amino acid derivaties | asymmetric reactions | hydrogenation | rhodium | Asymmetric reactions | Amino acid derivatives | Rhodium | Hydrogenation | BBM-928-A | CHEMISTRY, ORGANIC | METAL COMPLEXES | ALPHA-ACETAMIDOACRYLATES | HIGHLY ENANTIOSELECTIVE HYDROGENATION | LIGANDS | AMINO-ACIDS | INTERMEDIATE | ACTINOMADURA-LUZONENSIS | DERIVATIVES
Journal Article
Synthesis, ISSN 0039-7881, 1996, Volume 1996, Issue 2, pp. 223 - 229
Appropriately protected optically active tetrahydropyridazine-3-carboxylic acid and hexahydropyridazine-3-carboxylic acid were prepared via ring closure of... 
paper | ANTIBIOTICS | PEPTIDES | (3S)-2,3,4,5-TETRAHYDROPYRIDAZINE-3-CARBOXYLIC ACID | AMINO-ACIDS | ESTERS | L-156,602 | FERMENTATION | CHEMISTRY, ORGANIC | GLUTAMIC-ACID | ACTINOMADURA-LUZONENSIS | ANTRIMYCIN-DV
Journal Article
Tetrahedron, ISSN 0040-4020, 1993, Volume 49, Issue 38, pp. 8605 - 8628
The synthesis of various cyclic α-hydrazino esters is described. The key-step involves an intramolecular reaction of a highly reactive N-acylhydrazonium ion,... 
AZODICARBOXYLATE | ANTIBIOTICS | AMINATION | DESIGN | ANGIOTENSIN CONVERTING ENZYME | GLYCINE CATION EQUIVALENTS | AMINO-ACIDS | ESTERS | L-156,602 | CHEMISTRY, ORGANIC | ACTINOMADURA-LUZONENSIS
Journal Article
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