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Journal Article
Molecular Nutrition & Food Research, ISSN 1613-4125, 09/2015, Volume 59, Issue 9, pp. 1663 - 1673
Scope: In this study, the effects of lutein on neuroinflammation in lipopolysaccharide (LPS)-activated BV-2 microglia were investigated. Methods and results:... 
Lutein | Neuroinflammation | NF‐κB | Nrf2 | Microglia | NF-κB | PATHWAYS | CELLS | OXIDATIVE STRESS | METABOLITES | FOOD SCIENCE & TECHNOLOGY | DOWN-REGULATION | CAROTENOIDS | DIETARY LUTEIN | NF-kappa B | ZEAXANTHIN | ASTAXANTHIN | EXPRESSION | Tumor Necrosis Factor-alpha - metabolism | Microglia - metabolism | Heme Oxygenase-1 - metabolism | Phosphorylation | Reactive Oxygen Species - metabolism | JNK Mitogen-Activated Protein Kinases - metabolism | NF-kappa B - metabolism | Neurodegenerative Diseases - drug therapy | Proto-Oncogene Proteins c-akt - genetics | Lipopolysaccharides | Heme Oxygenase-1 - genetics | Cyclooxygenase 2 - genetics | Interleukin-1beta - metabolism | NF-E2-Related Factor 2 - genetics | p38 Mitogen-Activated Protein Kinases - metabolism | JNK Mitogen-Activated Protein Kinases - genetics | Proto-Oncogene Proteins c-akt - metabolism | Cell Survival - drug effects | Microglia - drug effects | Mitogen-Activated Protein Kinase 3 - genetics | Cells, Cultured | p38 Mitogen-Activated Protein Kinases - genetics | Inflammation | Animals | Mitogen-Activated Protein Kinase 3 - metabolism | NF-kappa B - genetics | Nitric Oxide Synthase Type II - genetics | NF-E2-Related Factor 2 - metabolism | Cyclooxygenase 2 - metabolism | Mice | Nitric Oxide - metabolism | Lutein - pharmacology | Nitric Oxide Synthase Type II - metabolism | Index Medicus
Journal Article
Journal Article
Journal Article
Journal Article
Food and Chemical Toxicology, ISSN 0278-6915, 08/2011, Volume 49, Issue 8, pp. 1745 - 1752
► The inhibitory effects of fucoidan on LPS-induced pro-inflammatory mediators in BV2 microglia were investigated. ► Fucoidan inhibited production of NO and... 
PGE2 | NF-κB | Fucoidan | Akt | MAPK | PATHWAYS | FOOD SCIENCE & TECHNOLOGY | ANTICOAGULANT | NEUROTOXICITY | ANTITUMOR | PGE | NF-kappa B | DISEASES | POLYSACCHARIDES | NITRIC-OXIDE | TOXICOLOGY | RECEPTORS | EXPRESSION | MOLECULAR-MECHANISMS | Tumor Necrosis Factor-alpha - metabolism | Microglia - metabolism | Plant Extracts - pharmacology | Tumor Necrosis Factor-alpha - genetics | Fucus - chemistry | JNK Mitogen-Activated Protein Kinases - metabolism | NF-kappa B - metabolism | Interleukin-1beta - genetics | Lipopolysaccharides - adverse effects | Proto-Oncogene Proteins c-akt - genetics | Cyclooxygenase 2 - genetics | Interleukin-1beta - metabolism | Chemokine CCL2 - metabolism | p38 Mitogen-Activated Protein Kinases - metabolism | JNK Mitogen-Activated Protein Kinases - genetics | Proto-Oncogene Proteins c-akt - metabolism | Microglia - cytology | Rabbits | NF-kappa B - antagonists & inhibitors | Microglia - drug effects | Anti-Inflammatory Agents - pharmacology | Nitric Oxide - antagonists & inhibitors | Down-Regulation | Cells, Cultured | p38 Mitogen-Activated Protein Kinases - genetics | Chemokine CCL2 - genetics | Polysaccharides - pharmacology | Dinoprostone - metabolism | Animals | Mitogen-Activated Protein Kinases - antagonists & inhibitors | NF-kappa B - genetics | Nitric Oxide Synthase Type II - genetics | Cyclooxygenase 2 - metabolism | Mitogen-Activated Protein Kinases - genetics | Mice | Dinoprostone - antagonists & inhibitors | Nitric Oxide - metabolism | Proto-Oncogene Proteins c-akt - antagonists & inhibitors | Mitogen-Activated Protein Kinases - metabolism | Nitric Oxide Synthase Type II - metabolism | Index Medicus
Journal Article
Journal Article
Immunity, ISSN 1074-7613, 08/2012, Volume 37, Issue 2, pp. 249 - 263
Inflammation-mediated neurodegeneration occurs in the acute and the chronic phases of multiple sclerosis (MS) and its animal model, experimental autoimmune... 
EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS | NITRIC-OXIDE PRODUCTION | INHIBITION | MULTIPLE-SCLEROSIS | PATHWAY | O-GLYCANS | DIFFERENTIATION | IMMUNOLOGY | EXPRESSION | T-CELLS | NEURONAL DYSFUNCTION | Tumor Necrosis Factor-alpha - metabolism | Microglia - metabolism | Central Nervous System - metabolism | Galectin 1 - immunology | Leukocyte Common Antigens - metabolism | Encephalomyelitis, Autoimmune, Experimental - metabolism | Humans | Encephalomyelitis, Autoimmune, Experimental - immunology | Galectin 1 - metabolism | NF-kappa B - metabolism | Central Nervous System - immunology | Multiple Sclerosis - physiopathology | Microglia - immunology | Female | Chemokine CCL2 - metabolism | p38 Mitogen-Activated Protein Kinases - metabolism | Interleukin-6 - metabolism | Multiple Sclerosis - metabolism | Microglia - cytology | Mice, Inbred C57BL | Mice, Knockout | Polysaccharides - metabolism | Encephalomyelitis, Autoimmune, Experimental - therapy | Animals | Galectin 1 - therapeutic use | Cyclic AMP Response Element-Binding Protein - metabolism | Multiple Sclerosis - immunology | Protein Binding | Mice | Central Nervous System - physiopathology | Astrocytes - metabolism | Nitric Oxide Synthase Type II - metabolism | Multiple sclerosis | Nervous system diseases | Neurosciences | Phosphatases | Analysis | Proteins | Statistical analysis | Neurodegeneration | Rodents | Lectins | Regulation | Kinases | Phosphatase | Immune system | Index Medicus | Brain | Animal models | Deactivation | Astrocytes | Glycoproteins | Inflammation | Gene deletion | Cell surface | Adoptive transfer | CD45 antigen | Experimental allergic encephalomyelitis | Nitric-oxide synthase | Microglia | Signal transduction | Tumor necrosis factor | Microglial cells | Monocyte chemoattractant protein 1 | galectin-1 | Antigens, CD45 | Nitric Oxide Synthase Type II | Tumor Necrosis Factor-alpha | Interleukin-6 | Multiple Sclerosis | Life Sciences | Encephalomyelitis, Autoimmune, Experimental | Polysaccharides | NF-kappa B | Central Nervous System | Immunology | Chemokine CCL2 | Cyclic AMP Response Element-Binding Protein | p38 Mitogen-Activated Protein Kinases | Galectin 1
Journal Article
Journal Article