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animals (42) 42
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signal transduction (27) 27
activated notch4 (22) 22
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expression (21) 21
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Journal of Biological Chemistry, ISSN 0021-9258, 03/2004, Volume 279, Issue 12, pp. 11657 - 11663
Notch4, a member of the Notch family of transmembrane receptors, is expressed primarily on endothelial cells. Activation of Notch in various cell systems has... 
CELLS | TUMOR-NECROSIS-FACTOR | ANGIOGENESIS | GENE | BIOCHEMISTRY & MOLECULAR BIOLOGY | RECEPTOR | JUN NH2-TERMINAL KINASE | EXPRESSION | ACTIVATED NOTCH4 | FAMILY
Journal Article
Journal Article
Multiple Sclerosis Journal, ISSN 1352-4585, 11/2013, Volume 19, Issue 13, pp. 1696 - 1703
Journal Article
Blood, ISSN 0006-4971, 02/2006, Volume 107, Issue 3, pp. 931 - 939
Delta-like 4 (DII4), a membrane-bound ligand for Notch1 and Notch4, is selectively expressed in the developing endothelium and in some tumor endothelium, and... 
VASCULAR DEVELOPMENT | SIGNALING PATHWAYS | DROSOPHILA-NOTCH | MAMMALIAN NOTCH | SEMAPHORIN-III | EMBRYONIC LETHALITY | GROWTH-FACTOR | HEMATOLOGY | TUBE FORMATION | MOUSE EMBRYO | ACTIVATED NOTCH4 | Neovascularization, Physiologic - drug effects | Receptors, Notch - metabolism | Humans | Vascular Endothelial Growth Factor A - metabolism | Blood Proteins - metabolism | Intercellular Signaling Peptides and Proteins - metabolism | Transfection | Basic Helix-Loop-Helix Transcription Factors - metabolism | Blood Proteins - genetics | Aspartic Acid Endopeptidases | Up-Regulation - physiology | Amyloid Precursor Protein Secretases | Umbilical Veins - cytology | Vascular Endothelial Growth Factor A - pharmacology | Endothelial Cells - physiology | Repressor Proteins - metabolism | Carbamates - pharmacology | Proto-Oncogene Proteins - metabolism | Endopeptidases - metabolism | Dipeptides - pharmacology | Cells, Cultured | Enzyme Inhibitors - pharmacology | Intercellular Signaling Peptides and Proteins - genetics | Vascular Endothelial Growth Factor Receptor-2 - metabolism | Umbilical Veins - physiology | Receptor, Notch1 - metabolism | Up-Regulation - drug effects | Neovascularization, Physiologic - physiology | Endothelial Cells - cytology | Protein Binding | Ligands | Receptor, Notch4 | Hemostasis, Thrombosis, and Vascular Biology
Journal Article
CANCER RESEARCH, ISSN 0008-5472, 10/2005, Volume 65, Issue 19, pp. 8690 - 8697
The Notch signaling pathway and the delta-like 4 ligand (DLL4) play key roles in embryonic vascular development. Many of the pathways involved in embryonic... 
ARTERIAL | SUPPRESSOR GENE | ANGIOGENESIS | ONCOLOGY | RBP-J-KAPPA | PATHWAY | EMBRYONIC LETHALITY | FIBROBLAST-GROWTH-FACTOR | HYPOXIA | RENAL-CARCINOMA | ACTIVATED NOTCH4
Journal Article
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY, ISSN 1357-2725, 05/2012, Volume 44, Issue 5, pp. 776 - 789
Epithelial-mesenchymal transition (EMT) is a process by which epithelial cells undergo phenotypic transition to mesenchymal cells and thus is involved in the... 
PATHWAYS | TGF-BETA | TUMOR PROGRESSION | TGF-beta 1 | RBP-J-KAPPA | BIOCHEMISTRY & MOLECULAR BIOLOGY | A549 | E-CADHERIN EXPRESSION | Snai1 | HYPOXIA | EMT | CELL BIOLOGY | CELL LUNG-CANCER | BONE-MARROW STROMA | LIGANDS | Notch signaling | ACTIVATED NOTCH4
Journal Article
by Dou, GR and Wang, YC and Hu, XB and Hou, LH and Wang, CM and Xu, JF and Wang, YS and Liang, YM and Yao, LB and Yang, AG and Han, H
FASEB JOURNAL, ISSN 0892-6638, 05/2008, Volume 22, Issue 5, pp. 1606 - 1617
In adults, angiogenic abnormalities are involved in not only tumor growth but several human inherited diseases as well. It is unclear, however, concerning how... 
PROGENITOR CELLS | TARGET | ARTERIOVENOUS-MALFORMATIONS | endothelial cells | choroidal neovascularization | angiogenesis | BIOCHEMISTRY & MOLECULAR BIOLOGY | CELL BIOLOGY | INHIBITION | Notch signaling | PATHWAY | GENES | BIOLOGY | TUMOR-GROWTH | EXPRESSION | ACTIVATED NOTCH4
Journal Article
CANCER RESEARCH, ISSN 0008-5472, 07/2008, Volume 68, Issue 13, pp. 5226 - 5235
Journal Article
Journal Article
Journal Article
Journal Article
FASEB Journal, ISSN 0892-6638, 06/2005, Volume 19, Issue 8, pp. 1027 - 1029
Journal Article
Journal Article
Breast Cancer Research, ISSN 1465-5411, 06/2011, Volume 13, Issue 3, pp. R63 - R63
Journal Article
Journal Article