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Critical Reviews in Toxicology, ISSN 1547-6898, 2013, Volume 44, Issue 1, pp. 1 - 49
Journal Article
Current medicinal chemistry, ISSN 0929-8673, 2014, Volume 21, Issue 24, pp. 2803 - 2821
Journal Article
Cell metabolism, ISSN 1550-4131, 07/2014, Volume 20, Issue 1, pp. 172 - 182
Oxysterols are cholesterol metabolites that serve multiple functions in lipid metabolism, including as liver X receptor (LXR) ligands. 27-hydroxycholesterol... 
ADHESION | SIGNALING PATHWAYS | HEART-DISEASE | DNA-BINDING | LIVER X RECEPTORS | INFLAMMATION | TRANSCRIPTION | ENDOCRINOLOGY & METABOLISM | NF-KAPPA-B | INTERLEUKIN-6 GENE-EXPRESSION | STEROL 27-HYDROXYLASE | CELL BIOLOGY | Steroid Hydroxylases - metabolism | Apolipoproteins E - deficiency | JNK Mitogen-Activated Protein Kinases - metabolism | Male | NF-kappa B - metabolism | I-kappa B Proteins - metabolism | Apolipoproteins E - metabolism | Cytochrome P450 Family 7 | RNA Interference | Estrogen Receptor alpha - metabolism | Female | Cytokines - genetics | Steroid Hydroxylases - genetics | Macrophages - immunology | Cell Line | Atherosclerosis - pathology | NF-KappaB Inhibitor alpha | Cytokines - metabolism | Endothelial Cells - metabolism | Inflammation | Cell Adhesion - drug effects | Cholesterol - metabolism | Hydroxycholesterols - pharmacology | Atherosclerosis - metabolism | Mice, Knockout | Macrophages - metabolism | Animals | Estrogen Receptor alpha - genetics | Mitogen-Activated Protein Kinase 3 - metabolism | Endothelial Cells - cytology | Apolipoproteins E - genetics | Steroid Hydroxylases - deficiency | Hydroxycholesterols - metabolism | Macrophages - drug effects | Mice | Endothelial Cells - drug effects | Mitogen-Activated Protein Kinase 1 - metabolism | RNA, Small Interfering - metabolism | Metabolites | Atherosclerosis | Estrogen | Cytochrome P-450 | Physiological aspects | Phenols | Cholesterol | Prevention | Blood circulation disorders | Liver | Endothelium
Journal Article
Journal Article
Journal of neurochemistry, ISSN 0022-3042, 12/2015, Volume 135, Issue 6, pp. 1113 - 1122
Journal Article
Cardiovascular diabetology, ISSN 1475-2840, 2019, Volume 18, Issue 1, pp. 1 - 20
Journal Article
PloS one, ISSN 1932-6203, 09/2016, Volume 11, Issue 9, p. e0162628
Peroxisome proliferator-activated receptor alpha (PPAR alpha) is a nuclear hormone receptor involved in the transcriptional regulation of lipid metabolism, fatty acid oxidation, and glucose homeostasis... 
RESPONSES | OXIDATIVE STRESS | MESSENGER-RNA EXPRESSION | HUMAN DERMAL FIBROBLASTS | INFLAMMATION | MULTIDISCIPLINARY SCIENCES | EPIDERMIS | ULTRAVIOLET | MECHANISMS | SUPEROXIDE-DISMUTASE | MODULATION | RNA, Small Interfering - genetics | Skin - metabolism | Humans | Young Adult | Aging - genetics | Aged, 80 and over | Adult | Female | Catalase - genetics | Cells, Cultured | Aging - radiation effects | PPAR alpha - genetics | Reverse Transcriptase Polymerase Chain Reaction | Skin - enzymology | Blotting, Western | Ultraviolet Rays - adverse effects | Hydrogen Peroxide - metabolism | Catalase - metabolism | Animals | Skin - radiation effects | Aged | Mice | PPAR alpha - metabolism | In Vitro Techniques | Gene Silencing - physiology | Antioxidants | Enzymes | Care and treatment | RNA | Physiological aspects | Skin | Fatty acids | Oxidative stress | Reactive oxygen species | Biomedical research | Transcription | Gene regulation | Irradiated | Homeostasis | Biology | Activation | Matrix metalloproteinase | Dermatitis | Signal transduction | Catalase | Rodents | Fibroblasts | Aging | Tumor necrosis factor-TNF | Oxidation | Metalloproteinase | Lipid metabolism | Growth factors | Interstitial collagenase | Medical research | Oxygen | Procollagen | Dermatology | U.V. radiation | Scavenging | Inflammation | Hairless | Metabolism | Collagenase 3 | Medicine | Ultraviolet radiation | Collagen | Irradiation | Ligands | Topical application
Journal Article
Journal Article
The Journal of biological chemistry, ISSN 0021-9258, 04/2015, Volume 290, Issue 16, pp. 10309 - 10324
Lysosomes are ubiquitous membrane-enclosed organelles filled with an acidic interior and are central to the autophagic, endocytic, or phagocytic pathway. In... 
GEMFIBROZIL | GAMMA | Retinoic Acid | BIOCHEMISTRY & MOLECULAR BIOLOGY | Astrocyte | AUTOPHAGY | LIPID-LOWERING DRUG | Peroxisome proliferator-activated Receptor (PPAR) | MESSENGER-RNAS | ADOPTIVE TRANSFER | Neurodegeneration | GENE-EXPRESSION | Lysosomal Storage Disease | RETINOID-X-RECEPTOR | CELLULAR CLEARANCE | UP-REGULATION | Retinoid X Receptor alpha - metabolism | Humans | Neurons - cytology | PPAR gamma - metabolism | Autophagy - drug effects | Brain - metabolism | Lysosomes - metabolism | Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha | Neurons - metabolism | Neurons - drug effects | PPAR gamma - genetics | Tretinoin - pharmacology | Astrocytes - cytology | Lysosomes - drug effects | Astrocytes - drug effects | Promoter Regions, Genetic | Brain - cytology | PPAR-beta - metabolism | Signal Transduction | Gene Expression Regulation | PPAR alpha - genetics | Gemfibrozil - pharmacology | Transcription Factors - genetics | PPAR-beta - genetics | Brain - drug effects | Transcription Factors - metabolism | Animals | Basic Helix-Loop-Helix Leucine Zipper Transcription Factors - genetics | Lipid Metabolism - drug effects | Retinoid X Receptor alpha - genetics | Protein Binding | Basic Helix-Loop-Helix Leucine Zipper Transcription Factors - metabolism | PPAR alpha - agonists | Mice | PPAR alpha - metabolism | Primary Cell Culture | Astrocytes - metabolism
Journal Article