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Cell death and differentiation, ISSN 1350-9047, 2018, Volume 25, Issue 1, pp. 161 - 168
Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Proteins | Therapy | Missense mutation | Mathematical analysis | p53 Protein | Transcription activation | Crime | Mutation | Gene expression | Protein interaction | Environmental conditions | Index Medicus | Review
Journal Article
Cancer cell, ISSN 1535-6108, 05/2012, Volume 21, Issue 5, pp. 614 - 625
Oncology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Neoplasms - metabolism | Reactive Oxygen Species - metabolism | Apoptosis - drug effects | Zinc - metabolism | Humans | Transcriptional Activation - drug effects | Structure-Activity Relationship | Mutation, Missense | Tumor Suppressor Protein p53 - genetics | Dose-Response Relationship, Drug | Transfection | Neoplasms - genetics | RNA Interference | Time Factors | Antineoplastic Agents - pharmacology | Thiosemicarbazones - pharmacology | Gene Expression Regulation, Neoplastic - drug effects | Binding Sites | Cell Line | Cell Survival - drug effects | Oxidation-Reduction | Mice, Inbred C57BL | Tumor Suppressor Protein p53 - metabolism | Mice, Transgenic | Chelating Agents - pharmacology | DNA - metabolism | Tumor Suppressor Protein p53 - drug effects | Gene Knock-In Techniques | Neoplasms - drug therapy | Xenograft Model Antitumor Assays | Animals | Tumor Burden - drug effects | Mice, Nude | Alleles | Protein Conformation | Mice | Mice, Inbred BALB C | Tumor Suppressor Protein p53 - chemistry | Oxidative Stress - drug effects | Neoplasms - pathology | Care and treatment | Nuclear radiation | Oncology, Experimental | Research | Tumor proteins | Health aspects | Cancer | Index Medicus | Antitumor agents | Lymphocytes B | Xenografts | Data processing | Drug development | Zinc | p53 protein | Apoptosis | Structure-function relationships | Tumors
Journal Article
Nature reviews. Cancer, ISSN 1474-175X, 01/2018, Volume 18, Issue 2, pp. 89 - 102
Life Sciences & Biomedicine | Oncology | Science & Technology | Molecular targeted therapy | Care and treatment | Gene mutations | Innovations | Tumor suppressor genes | Health aspects | Cancer | Medical research | Deactivation | p53 Protein | Clinical trials | Recovery of function | Activation | Pharmacology | Inactivation | Cell death | Mutation | Tumors | Apoptosis | Index Medicus | Medicin och hälsovetenskap
Journal Article
Cancer cell, ISSN 1535-6108, 12/2012, Volume 22, Issue 6, pp. 751 - 764
Oncology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Cellular Senescence - genetics | Proto-Oncogene Proteins c-mdm2 - genetics | Animals | Cell Death - genetics | Cell Transformation, Neoplastic | Transcriptional Activation | Cells, Cultured | Cell Survival - genetics | Mice | Mutation | Gene Knock-In Techniques - methods | Tumor Suppressor Protein p53 - genetics | Analysis | Oncology, Experimental | Stem cells | Research | Tumor proteins | Tumors | Cancer | Index Medicus
Journal Article
Nature (London), ISSN 0028-0836, 2016, Volume 534, Issue 7609, pp. 647 - 651
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Lung Neoplasms - drug therapy | Colonic Neoplasms - genetics | Adenocarcinoma - pathology | Adenocarcinoma of Lung | Proto-Oncogene Proteins p21(ras) - genetics | Humans | Receptor, Fibroblast Growth Factor, Type 1 - metabolism | Drug Resistance, Neoplasm | Lung Neoplasms - pathology | Pyridazines - pharmacology | Female | Pyrimidinones - pharmacology | Adenocarcinoma - genetics | Cell Death - drug effects | Imidazoles - therapeutic use | Phosphorylation - drug effects | Pyridazines - therapeutic use | Disease Models, Animal | Lung Neoplasms - genetics | Pancreatic Neoplasms - pathology | Pyrimidinones - therapeutic use | Mitogen-Activated Protein Kinase Kinases - antagonists & inhibitors | Mutant Proteins - genetics | Antineoplastic Combined Chemotherapy Protocols | Pancreatic Neoplasms - genetics | Imidazoles - pharmacology | Enzyme Activation - drug effects | Adenocarcinoma - drug therapy | Receptor, Fibroblast Growth Factor, Type 1 - antagonists & inhibitors | Xenograft Model Antitumor Assays | Feedback, Physiological | Animals | MAP Kinase Signaling System - drug effects | Colonic Neoplasms - pathology | Cell Proliferation - drug effects | Mice | Pyridones - therapeutic use | Mutation | Pyridones - pharmacology | Drug Screening Assays, Antitumor | Molecular targeted therapy | Care and treatment | Cell death | Lung cancer | Methods | Cancer cells | Phosphorylation | Chemotherapy | Inhibitor drugs | Drug resistance | Tumors | Index Medicus
Journal Article
Nature genetics, ISSN 1061-4036, 09/2014, Volume 46, Issue 10, pp. 1140 - 1146
Life Sciences & Biomedicine | Genetics & Heredity | Science & Technology | Amino Acid Sequence | Macrophage Activation Syndrome - blood | Interleukin-18 - blood | Oligonucleotide Array Sequence Analysis | Humans | Molecular Sequence Data | Gene Expression Profiling | Mutation, Missense | Sequence Analysis, DNA | Inflammasomes - genetics | Inflammation - blood | CARD Signaling Adaptor Proteins - genetics | Sequence Homology, Amino Acid | Exome - genetics | Macrophages - metabolism | Inflammation - genetics | Female | Macrophage Activation Syndrome - genetics | Child | Interleukin-18 - metabolism | Calcium-Binding Proteins - genetics | Causes of | Inflammation | Genetic aspects | Gene mutations | Macrophages | Health aspects | Disease | Cytokines | Pathogenesis | Rheumatic diseases | Cytotoxicity | Arthritis | Mutation | Hearing impairment | Gene expression | Fever | Crystal structure | Index Medicus
Journal Article
Science (American Association for the Advancement of Science), ISSN 0036-8075, 09/2016, Volume 353, Issue 6304, pp. 1161 - 1165
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Lung Neoplasms - genetics | Nitrogen - metabolism | Pancreatic Neoplasms - metabolism | Carcinoma, Non-Small-Cell Lung - genetics | Proto-Oncogene Proteins p21(ras) - genetics | Transaminases - genetics | Amino Acids, Branched-Chain - metabolism | Humans | Lung Neoplasms - metabolism | Mice, Inbred C57BL | Pregnancy Proteins - genetics | Carcinoma, Non-Small-Cell Lung - metabolism | Carcinoma, Pancreatic Ductal - metabolism | Gene Expression Regulation, Neoplastic | Male | Pancreatic Neoplasms - genetics | Organ Specificity | Carcinoma, Pancreatic Ductal - genetics | Animals | Metabolic Networks and Pathways | Minor Histocompatibility Antigens - genetics | Mice | Mutation | Gene mutations | Branched chain amino acids | Pancreatic cancer | Genetic aspects | Lung cancer, Non-small cell | Health aspects | Amino acid metabolism | Genetics | Amino acids | Tissues | Cancer | Index Medicus | Origins | Enzymes | Lungs | Activation | Formations | Tumors
Journal Article
American journal of human genetics, ISSN 0002-9297, 07/2012, Volume 91, Issue 1, pp. 171 - 179
Life Sciences & Biomedicine | Genetics & Heredity | Science & Technology | Fundamental and applied biological sciences. Psychology | Biological and medical sciences | Molecular and cellular biology | Genetics of eukaryotes. Biological and molecular evolution | Medical sciences | Medical genetics | Humans | Transcriptional Activation | Child, Preschool | Models, Molecular | Male | Hearing Loss, Sensorineural - genetics | Mutation, Missense | Strabismus - genetics | Mobius Syndrome - genetics | Homeodomain Proteins - genetics | Facial Paralysis - genetics | Founder Effect | Phenotype | Animals | Pedigree | Base Sequence | Female | Transcription, Genetic | Mice | Child | Proteins | Genotype & phenotype | Mutation | Minority & ethnic groups | Genes | Deoxyribonucleic acid--DNA | Index Medicus | Report
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