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Arteriosclerosis, Thrombosis, and Vascular Biology, ISSN 1079-5642, 03/2014, Volume 34, Issue 3, pp. 487 - 498
Low-density lipoprotein receptor–related protein-1 (LRP1) is a large endocytic and signaling receptor that is widely expressed. In the liver, LRP1 plays an... 
Extracellular matrix | LRP1 | fVIII | Elastin | Aneurysm | aneurysm | GROWTH-FACTOR-RECEPTOR | FACTOR-VIII | DEPENDENT PHOSPHATIDYLINOSITOL 3-KINASE | MUSCLE-CELL PROLIFERATION | elastin | VON-WILLEBRAND-FACTOR | BLOOD-BRAIN-BARRIER | ALPHA-2-MACROGLOBULIN RECEPTOR | APOLIPOPROTEIN-E | PLASMINOGEN-ACTIVATOR | UROKINASE RECEPTOR | PERIPHERAL VASCULAR DISEASE | HEMATOLOGY | extracellular matrix | Muscle, Smooth, Vascular - metabolism | Humans | Low Density Lipoprotein Receptor-Related Protein-1 - chemistry | Extracellular Matrix - metabolism | Low Density Lipoprotein Receptor-Related Protein-1 - physiology | Tumor Suppressor Proteins - deficiency | Tumor Suppressor Proteins - genetics | Receptors, LDL - deficiency | Models, Animal | Lipoproteins, LDL - metabolism | Peptide Hydrolases - metabolism | von Willebrand Factor - metabolism | Elastin - metabolism | Receptors, LDL - genetics | Signal Transduction | Liver - metabolism | Transforming Growth Factor beta - physiology | Models, Molecular | Organ Specificity | Atherosclerosis - metabolism | Endocytosis - physiology | Mice, Knockout | Tumor Suppressor Proteins - physiology | Macrophages - metabolism | Platelet-Derived Growth Factor - metabolism | Animals | Protein Conformation | Mice | Blood Coagulation - physiology | Factor VIII - metabolism | Receptors, LDL - physiology | Thromboplastin - metabolism | Aneurysm - prevention & control
Journal Article
Nature Medicine, ISSN 1078-8956, 04/2010, Volume 16, Issue 4, pp. 438 - 445
Class Ia phosphoinositide 3-kinase (PI3K), an essential mediator of the metabolic actions of insulin, is composed of a catalytic (p110 alpha or p110 beta) and... 
MEDICINE, RESEARCH & EXPERIMENTAL | METABOLIC SYNDROME | PHOSPHATIDYLINOSITOL 3-KINASE | ER STRESS | BIOCHEMISTRY & MOLECULAR BIOLOGY | ENDOPLASMIC-RETICULUM STRESS | P85-ALPHA SUBUNIT | CELL BIOLOGY | SKELETAL-MUSCLE | MESSENGER-RNA | INSULIN-RESISTANCE | PURIFICATION METHOD | ADIPOSE-TISSUE | Insulin - physiology | Endoplasmic Reticulum - metabolism | Activating Transcription Factor 6 | Phosphatidylinositol 3-Kinases - metabolism | Cell Nucleus - physiology | X-Box Binding Protein 1 | Endoribonucleases - physiology | Gene Knockdown Techniques | Trans-Activators - physiology | DNA-Binding Proteins - metabolism | Cell Nucleus - metabolism | Membrane Proteins - physiology | Stress, Physiological - physiology | Cell Line | Unfolded Protein Response - drug effects | DNA-Binding Proteins - physiology | Transcription Factors - physiology | Protein-Serine-Threonine Kinases - physiology | Liver - metabolism | Endoplasmic Reticulum - physiology | Regulatory Factor X Transcription Factors | Transcription Factors - metabolism | Animals | Tunicamycin - pharmacology | Liver - physiology | Phosphatidylinositol 3-Kinases - physiology | Mice | Apoptosis - physiology | Unfolded Protein Response - physiology | Transcription factors | Physiological aspects | Causes of | Insulin resistance | Genetic aspects | Research | Binding proteins | Protein kinases | Catalysis | Kinases | Metabolism | Protein folding | Insulin
Journal Article
Circulation, ISSN 0009-7322, 06/2001, Volume 103, Issue 22, pp. 2717 - 2723
Journal Article
PLoS ONE, ISSN 1932-6203, 11/2013, Volume 8, Issue 11, p. e80883
Background: Kaempferol has been proposed as a potential drug for cancer chemoprevention and treatment because it is a natural polyphenol contained in... 
MIGRATION | INACTIVATION | INVASION | COLORECTAL-CANCER | INFLAMMATION | MULTIDISCIPLINARY SCIENCES | TISSUE INHIBITOR | FLAVONOIDS | PROGNOSTIC-SIGNIFICANCE | NF-KAPPA-B | CARCINOMA | Transcription, Genetic - drug effects | Protein Binding - genetics | Nitriles - pharmacology | DNA, Neoplasm - metabolism | Humans | Cell Survival - genetics | Extracellular Signal-Regulated MAP Kinases - metabolism | RNA, Messenger - metabolism | Transcription Factor AP-1 - metabolism | Cell Movement - genetics | Tissue Inhibitor of Metalloproteinase-2 - metabolism | Protein Binding - drug effects | Gene Expression Regulation, Neoplastic - drug effects | Phosphorylation - drug effects | Mouth Neoplasms - enzymology | Cell Survival - drug effects | Butadienes - pharmacology | Matrix Metalloproteinase 2 - metabolism | Neoplasm Invasiveness | RNA, Messenger - genetics | Signal Transduction - genetics | Down-Regulation - drug effects | Cell Movement - drug effects | Matrix Metalloproteinase 2 - genetics | Matrix Metalloproteinase Inhibitors - pharmacology | Signal Transduction - drug effects | Cell Line, Tumor | Mouth Neoplasms - pathology | Kaempferols - pharmacology | Prevention | Medical research | Care and treatment | Squamous cell carcinoma | RNA | Analysis | Medicine, Experimental | Metastasis | Cardiovascular diseases | Mouth cancer | Cancer | Biotechnology | Food plants | Transcription factors | Tongue | Phosphorylation | Transcription | Oral cancer | Laboratories | Gene regulation | Colorectal cancer | Otolaryngology | Biochemistry | Matrix metalloproteinase | Tissue inhibitor of metalloproteinase 2 | Cancer therapies | Metastases | Angiogenesis | Signal transduction | Cell cycle | Physiology | Metalloproteinase | Food | Kaempferol | Activator protein 1 | Melanoma | Extracellular signal-regulated kinase | c-Jun protein | Plant protection | Breast cancer | Gene expression | Gelatinase A | Studies | Signaling | Bone cancer | Chemotherapy | Flavonoids | Hospitals | Molecular modelling | Cell migration | Apoptosis
Journal Article
Arteriosclerosis, Thrombosis, and Vascular Biology: Journal of the American Heart Association, ISSN 1079-5642, 06/2002, Volume 22, Issue 6, pp. 914 - 920
Journal Article
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 01/2001, Volume 276, Issue 2, pp. 1486 - 1493
Journal Article
Journal Article
Journal Article
Journal Article