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Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 6/2009, Volume 106, Issue 22, pp. 8888 - 8893
Journal Article
Molecular Microbiology, ISSN 0950-382X, 08/2014, Volume 93, Issue 4, pp. 583 - 586
Summary Hsp100/Clp protease complexes are molecular machines important for cellular protein homeostasis and are concurrently embedded in the control of various... 
CLPP PROTEASE | CASEINOLYTIC PROTEASE | COMPLEX | ANTIBIOTICS | ADAPTER PROTEINS | INHIBITION | CYCLOMARIN | TUBERCULOSIS | BIOCHEMISTRY & MOLECULAR BIOLOGY | MICROBIOLOGY | PROTEOLYSIS | PEPTIDASE | Bacterial Proteins - metabolism | Endopeptidase Clp - metabolism | Heat-Shock Proteins - metabolism | Mycobacterium tuberculosis - enzymology | Proteases | Proteolysis
Journal Article
Journal Article
FEBS Letters, ISSN 0014-5793, 05/2019, Volume 593, Issue 9, pp. 962 - 970
The prokaryotic N‐degron pathway depends on the Clp chaperone‐protease system and the ClpS adaptor for recognition of N‐degron bearing substrates. Plant... 
protease | adaptor | Arabidopsis thaliana | chloroplast | N‐degron | ClpS1 | COMPLEX | ADAPTER PROTEIN CLPS | BIOCHEMISTRY & MOLECULAR BIOLOGY | ESCHERICHIA-COLI | MITOCHONDRIA | PROTEOLYSIS | SUBSTRATE RECOGNITION | CELL BIOLOGY | Arabidopsis thaliana | N-degron | BIOPHYSICS | STRUCTURAL BASIS | DEGRADATION | COMPONENT | END RULE PATHWAY
Journal Article
Plant and Cell Physiology, ISSN 0032-0781, 03/2018, Volume 59, Issue 3, pp. 624 - 636
Abstract Proteins that are to be eliminated must be proficiently recognized by proteolytic systems so that inadvertent elimination of useful proteins is... 
Arabidopsis thaliana | AtClpS1 | N-end rule | N-degron | Chloroplasts | Proteolysis | ADAPTER PROTEIN CLPS | ESCHERICHIA-COLI | DEGRADATION SIGNALS | PLANT SCIENCES | CELL BIOLOGY | ISOTHERMAL TITRATION CALORIMETRY | AAA+ PROTEASES | STRUCTURAL BASIS | TERMINAL METHIONINE CLEAVAGE | PLASMODIUM-FALCIPARUM | FORMYL-METHIONINE | MOLECULAR-BASIS
Journal Article
Nature Structural & Molecular Biology, ISSN 1545-9993, 10/2010, Volume 17, Issue 10, pp. 1175 - 1181
Journal Article
SpringerPlus, ISSN 2193-1801, 12/2014, Volume 3, Issue 1, pp. 1 - 8
Several Ubr ubiquitin ligases recognize the N-terminal amino acid of substrate proteins and promote their degradation via the Arg/N-end rule pathway. The... 
Yeast | Ubiquitin ligase | N-recognin | N-end rule pathway | Oligopeptide transporter | Ubr protein | Science, general | FISSION YEAST | ADAPTER PROTEIN CLPS | MULTIDISCIPLINARY SCIENCES | ESCHERICHIA-COLI | SUBSTRATE RECOGNITION | STRUCTURAL BASIS | MISFOLDED PROTEIN | UBIQUITIN LIGASE UBR1 | END RULE PATHWAY | CYTOSOLIC PROTEINS | TRANSCRIPTIONAL REPRESSOR
Journal Article
EMBO Molecular Medicine, ISSN 1757-4676, 04/2009, Volume 1, Issue 1, pp. 37 - 49
Journal Article
RESEARCH IN MICROBIOLOGY, ISSN 0923-2508, 11/2009, Volume 160, Issue 9, pp. 629 - 636
General and regulated proteolysis in bacteria is crucial for cellular homeostasis and relies on high substrate specificity of the executing AAA+ proteases.... 
ADAPTER PROTEIN CLPS | DNA-DAMAGE | TAGGING SYSTEM | N-end rule | MICROBIOLOGY | Protein quality control | CLPX-RECOGNITION SIGNALS | SPECIFICITY-ENHANCING FACTOR | Clp/Hsp100 | DEPENDENT PROTEOLYSIS | SUBSTRATE-SPECIFICITY | DEGRADATION TAG | AAA protein | Proteolysis | STRUCTURAL BASIS
Journal Article
International Journal of Molecular Sciences, ISSN 1661-6596, 11/2018, Volume 19, Issue 11, p. 3651
ClpC1 hexamers couple the energy of ATP hydrolysis to unfold and, subsequently, translocate specific protein substrates into the associated ClpP protease.... 
Adaptor proteins | ATP-dependent protease | Mycobacterium tuberculosis | ClpS | Clp/Hsp100 proteins | ClpC1 | Hsp100 proteins | COMPLEX | PHOTOINDUCED PEPTIDE CLEAVAGE | Clp | CRYSTAL-STRUCTURE | BIOCHEMISTRY & MOLECULAR BIOLOGY | ESCHERICHIA-COLI | COMPONENTS | adaptor proteins | CHAPERONE | CHEMISTRY, MULTIDISCIPLINARY | PROTEASES | STRUCTURAL BASIS | DEGRADATION | BINDING
Journal Article
Frontiers in Molecular Biosciences, ISSN 2296-889X, 07/2017, Volume 4, p. 44
Here, we review the diverse roles and functions of AAA+ protease complexes in protein homeostasis, control of stress response and cellular development pathways... 
Adaptor proteins | McsB | Regulatory proteolysis | AAA+ protease complexes | Bacillus subtilis | Chaperones | Hsp100/Clp proteins | Protein quality control | protein quality control | regulatory proteolysis | chaperones
Journal Article