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1. Full Text Intravascular injections of adenoassociated viral vector serotypes rh10 and PHP.B transduce murine sciatic nerve axons
by Anderson, Hans E and Schaller, Kristin L and Caldwell, John H and Weir, Richard F. ff
Neuroscience letters, ISSN 0304-3940, 07/2019, Volume 706, pp. 51 - 55
Peripheral nerve | Intravascular injection | Motor neuron | Mouse | Green fluorescent protein | Adenoassociated viral vector | Neurosciences | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Motor Neurons - metabolism | Sciatic Nerve - metabolism | Animals | Transduction, Genetic | Axons - metabolism | Mice | Dependovirus | Genetic Vectors | Fluorescence | Neurons | Genetic engineering | Index Medicus | mouse | peripheral nerve | intravascular injection | green fluorescent protein | motor neuron
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2. Full Text On the development of optical peripheral nerve interfaces
by Anderson, Hans and Weir, Richard
Neural regeneration research, ISSN 1673-5374, 3/2019, Volume 14, Issue 3, pp. 425 - 436
adenoassociated viral vector | GCaMP | implantable microscopy | optical peripheral nerve interface | optical neural interface | lentiviral vectors | ArcLight | optogenetics | peripheral nerve interfaces | viral vectors | Neurosciences | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Optic nerve | Research | Phase interfaces | Analysis | Prevalence studies (Epidemiology) | Electrodes | Interfaces | Prostheses | Surgical techniques | Transplants & implants | Amputation | Spinal cord injuries | Trauma | Quality of life | Questioning | Review | peripheral nerve interfaces; optogenetics; optical neural interface; optical peripheral nerve interface; GCaMP; ArcLight; adenoassociated viral vector; lentiviral vectors; viral vectors; implantable microscopy
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3. Full Text Viral Vector-Based Models of Parkinson’s Disease
by Van der Perren, Anke and Van den Haute, Chris and Baekelandt, Veerle
5/2014, Current Topics in Behavioral Neurosciences, ISBN 3662463431, Volume 22
Lentiviral vectors | α-Synuclein | Animal models | Parkinson’s disease | Adeno-associated viral vectors | Adenoassociated viral vectors | Animals | Parkinson Disease - genetics | Dependovirus | Genetic Vectors | Lentivirus | alpha-Synuclein - metabolism | Disease Models, Animal
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4. Full Text Astrocytes are key but indirect contributors to the development of the symptomatology and pathophysiology of Huntington's disease
by Meunier, Cécile and Merienne, Nicolas and Jollé, Charlotte and Déglon, Nicole and Pellerin, Luc
Glia, ISSN 0894-1491, 11/2016, Volume 64, Issue 11, pp. 1841 - 1856
striatum | mouse model | polyglutamine expansion | glia | adenoassociated viral vectors | Polyglutamine expansion | Striatum | Adenoassociated viral vectors | Mouse model | Glia | Neurosciences | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Neurons - pathology | Locomotion - genetics | Humans | Huntington Disease - pathology | Astrocytes - pathology | Glutamine - metabolism | Glial Fibrillary Acidic Protein - metabolism | Glutamate-Ammonia Ligase - metabolism | Disease Models, Animal | Cyclophilin A - metabolism | Gene Expression Regulation - genetics | Huntingtin Protein - metabolism | Mice, Transgenic | Nuclear Proteins - metabolism | Mutation - genetics | Dopamine and cAMP-Regulated Phosphoprotein 32 - metabolism | Huntington Disease - complications | Nerve Tissue Proteins - metabolism | Animals | Glutamate-Ammonia Ligase - genetics | Brain - pathology | Huntington Disease - genetics | Glutamic Acid - metabolism | Mice | Huntingtin Protein - genetics | Locomotion - physiology | Astrocytes - metabolism | Neurons | Health aspects | Nervous system diseases | Huntingtons disease | Rodents | Index Medicus
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5. Full Text AAVPG: A vigilant vector where transgene expression is induced by p53
by Bajgelman, Marcio C and Medrano, Ruan F.V and Carvalho, Anna Carolina P.V and Strauss, Bryan E
Virology (New York, N.Y.), ISSN 0042-6822, 2013, Volume 447, Issue 1, pp. 166 - 171
Infectious Disease | Physiologic stress | Viral vector | Mechanical stress | Gene regulation | Hypoxia | Bioluminescence imaging | Gene therapy | Adenoassociated virus | Doxorubicin | p53 | P53 | Life Sciences & Biomedicine | Science & Technology | Virology | Dependovirus - genetics | Promoter Regions, Genetic | Gene Expression - drug effects | Mice, Inbred C57BL | Stress, Physiological | Tumor Suppressor Protein p53 - metabolism | Antineoplastic Agents - administration & dosage | Luciferases - genetics | Neoplasms - drug therapy | Animals | Biosensing Techniques - methods | Female | Mice | Genetic Vectors | Transgenes | Genes, Reporter | Luciferases - biosynthesis | Disease Models, Animal | Doxorubicin - administration & dosage | Tumor proteins | Gene expression | Anthracyclines | Index Medicus | GENE THERAPY | NEOPLASMS | BIOMEDICAL RADIOGRAPHY | DOXORUBICIN | PHOTONS | IN VIVO | 60 APPLIED LIFE SCIENCES | DNA DAMAGES | STRESSES | COBALT CHLORIDES | ANOXIA | PROMOTERS | IN VITRO | GENES | MICE | GENE REGULATION | BIOLUMINESCENCE | VIRUSES
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6. Full Text Antisense gene delivered by an adenoassociated viral vector inhibits iron uptake in human intestinal cells: Potential application in hemochromatosis
by Ezquer, Fernando and Núñez, Marco Tulio and Israel, Yedy
Biochemical pharmacology, ISSN 0006-2952, 2005, Volume 69, Issue 11, pp. 1559 - 1566
Antisense | Iron | Hemochromatosis | Caco-2 cells | Adenoassociated vector | Gene therapy | Life Sciences & Biomedicine | Pharmacology & Pharmacy | Science & Technology | Biological and medical sciences | Pharmacology. Drug treatments | Medical sciences | Caco-2 Cells | Intestines - drug effects | Cell Line | Dependovirus - genetics | Gene Targeting - methods | Hemochromatosis - therapy | Iron - antagonists & inhibitors | Humans | Intestines - metabolism | Hemochromatosis - metabolism | RNA, Antisense - administration & dosage | Iron - metabolism | Genetic Vectors | Hemochromatosis - genetics | RNA, Antisense - genetics | Virus diseases | Messenger RNA | Dimethyltryptamine | Ligases | Genetic research | Antisense RNA | Ribonuclease | Universities and colleges | Health aspects | Index Medicus
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7. Full Text Structural and functional neuroprotection in a rat model of Huntington’s disease by viral gene transfer of GDNF
by McBride, Jodi L and During, Matthew J and Wuu, Joanne and Chen, Er-Yun and Leurgans, Sue E and Kordower, Jeffrey H
Experimental neurology, ISSN 0014-4886, 2003, Volume 181, Issue 2, pp. 213 - 223
Glial cell line-derived neurotrophic factor | Huntington’s disease | Rat | Gene therapy | 3-Nitropropionic acid | Adenoassociated viral vector | Huntington's disease | Neurosciences | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Neurology | Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy | Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases | Transfusions. Complications. Transfusion reactions. Cell and gene therapy | Applied cell therapy and gene therapy | Biological and medical sciences | Medical sciences | Dependovirus - genetics | Green Fluorescent Proteins | Huntington Disease - pathology | Leukocyte Common Antigens - biosynthesis | Rats, Inbred Lew | Motor Activity - drug effects | Male | Corpus Striatum - metabolism | Neuroprotective Agents - metabolism | Luminescent Proteins - biosynthesis | Huntington Disease - therapy | Glial Cell Line-Derived Neurotrophic Factor | Behavior, Animal - drug effects | Neuroprotective Agents - administration & dosage | Corpus Striatum - pathology | Disease Models, Animal | Severity of Illness Index | Huntington Disease - chemically induced | Rats | Nerve Growth Factors - administration & dosage | Treatment Outcome | Nerve Growth Factors - biosynthesis | Stereotaxic Techniques | Motor Activity - genetics | Injections | Animals | Neurologic Examination | Nerve Growth Factors - genetics | Nitro Compounds | Propionates | Corpus Striatum - drug effects | Luminescent Proteins - genetics | Genetic Therapy - methods | Index Medicus
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8. Full Text The potential for targeted rewriting of epigenetic marks in COPD as a new therapeutic approach
by Wu, Dan-Dan and Song, Juan and Bartel, Sabine and Krauss-Etschmann, Susanne and Rots, Marianne G and Hylkema, Machteld N
Pharmacology & therapeutics (Oxford), ISSN 0163-7258, 02/2018, Volume 182, pp. 1 - 14
DNA methylation | Histone modification | microRNA | Delivery | Epigenetic editing | COPD | ADENOASSOCIATED VIRAL VECTORS | OBSTRUCTIVE PULMONARY-DISEASE | MESSENGER-RNA | ALLERGIC AIRWAYS DISEASE | LUNG GENE-THERAPY | ARTIFICIAL TRANSCRIPTION FACTORS | Review | COMPACTED DNA NANOPARTICLES | FINGER NUCLEASE PROTEINS | IN-VIVO EVALUATION | Journal Article | EPIGENOME-WIDE ASSOCIATION | Life Sciences & Biomedicine | Pharmacology & Pharmacy | Science & Technology | Epigenesis, Genetic - drug effects | Humans | Molecular Targeted Therapy - methods | Pulmonary Disease, Chronic Obstructive - drug therapy | Index Medicus
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