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Journal Article
Chembiochem : a European journal of chemical biology, ISSN 1439-4227, 10/2016, Volume 17, Issue 20, pp. 1951 - 1960
Journal Article
Science (American Association for the Advancement of Science), ISSN 0036-8075, 04/2011, Volume 332, Issue 6027, pp. 322 - 327
.... We report the crystal structure of the A(2A) adenosine receptor (A(2A)AR) bound to an agonist UK-432097... 
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Adenosine | Research | Properties | Protein binding
Journal Article
Science (American Association for the Advancement of Science), ISSN 0036-8075, 11/2008, Volume 322, Issue 5905, pp. 1211 - 1217
.... We have determined the crystal structure of the human A(2A) adenosine receptor, in complex with a high- affinity subtype- selective antagonist, ZM241385... 
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Adenosine | G proteins | Research | Structure
Journal Article
Angewandte Chemie (International ed.), ISSN 1433-7851, 07/2019, Volume 58, Issue 28, pp. 9399 - 9403
... NMR spectroscopy and advanced molecular dynamics simulations we describe a novel inactive state of the adenosine 2A receptor which is stabilised by the aminotriazole antagonist Cmpd‐1... 
conformational flexibility | G-protein coupled receptor | molecular dynamics | NMR spectroscopy | inactive state | Physical Sciences | Chemistry | Chemistry, Multidisciplinary | Science & Technology | Proteins | Molecular dynamics | Nuclear magnetic resonance spectroscopy | Adenosine | Magnetic resonance spectroscopy | Receptors | Nuclear magnetic resonance--NMR | Aminotriazole | Index Medicus
Journal Article
Journal Article
The Journal of clinical investigation, ISSN 1558-8238, 02/2017, Volume 127, Issue 3, pp. 929 - 941
Journal Article
Brain, behavior, and immunity, ISSN 0889-1591, 10/2013, Volume 33, pp. 112 - 122
.... A single intrathecal dose of adenosine 2A receptor (A2AR) agonist was previously reported to produce a multi-week reversal of allodynia in a chronic constriction injury (CCI... 
Psychiatry | Allergy and Immunology | ATL313 | Interleukin-10 | Protein kinase | Astrocytes | Rats | Intrathecal | Mechanical allodynia | Microglia | Neurosciences | Immunology | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Inflammation - pathology | Constriction, Pathologic - pathology | Male | Adenosine A2 Receptor Agonists - therapeutic use | Hyperalgesia - pathology | Signal Transduction - immunology | Ligation | Inflammation - drug therapy | Cyclic AMP-Dependent Protein Kinases - antagonists & inhibitors | Sciatic Neuropathy - drug therapy | Injections, Spinal | Piperidines - administration & dosage | Protein Kinase C - physiology | Hyperalgesia - metabolism | Cells, Cultured | Sciatic Neuropathy - pathology | Protein Kinase C - antagonists & inhibitors | Random Allocation | Rats, Sprague-Dawley | Sciatic Neuropathy - enzymology | Adenosine A2 Receptor Agonists - administration & dosage | Cyclic AMP-Dependent Protein Kinases - physiology | Animals | Constriction, Pathologic - drug therapy | Signal Transduction - drug effects | Piperidines - therapeutic use | Constriction, Pathologic - enzymology | Chronic Disease | Hyperalgesia - enzymology | Inflammation - enzymology | Protein kinases | Index Medicus | intrathecal | mechanical allodynia | rats | astrocytes | interleukin-10 | microglia | protein kinase
Journal Article