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Journal Article
1981, ISBN 041215840X, Volume 12., ix, 365
Book
Purinergic Signalling, ISSN 1573-9538, 9/2015, Volume 11, Issue 3, pp. 389 - 407
Adenosine receptors (ARs) have emerged as new drug targets. The majority of data on affinity/potency and selectivity of AR ligands described in the literature... 
Neurosciences | Agonist | Biomedicine | Human Physiology | Cancer Research | Selectivity | Potency | Antagonist | Pharmacology/Toxicology | Species differences | Biomedicine general | XANTHINE DERIVATIVES | NEUROSCIENCES | STRIATAL MEMBRANES | PROTEIN-COUPLED ADENOSINE | P2Y RECEPTORS | A(2B) RECEPTORS | INTERNATIONAL UNION | LIGANDS | A(2A) RECEPTOR | HIGHLY POTENT | PARKINSONS-DISEASE | Cricetulus | Species Specificity | Humans | DNA, Complementary - genetics | Adenosine A1 Receptor Antagonists - pharmacology | Adenosine A2 Receptor Agonists - metabolism | Receptor, Adenosine A2B - genetics | Structure-Activity Relationship | Adenosine A1 Receptor Antagonists - metabolism | Adenosine A2 Receptor Antagonists - metabolism | Adenosine A2 Receptor Agonists - pharmacology | Adenosine A3 Receptor Agonists - pharmacology | Adenosine A1 Receptor Agonists - pharmacology | Receptor, Adenosine A2B - drug effects | Receptor, Adenosine A2A - genetics | Adenosine A3 Receptor Antagonists - pharmacology | Cell Membrane - metabolism | Adenosine A3 Receptor Agonists - metabolism | Cyclic AMP - metabolism | Arrestin - metabolism | Cell Membrane - drug effects | DNA, Complementary - drug effects | CHO Cells | Cricetinae | Receptors, Purinergic P1 - genetics | Rats | Receptor, Adenosine A2A - metabolism | Receptor, Adenosine A2B - metabolism | Receptor, Adenosine A2A - drug effects | Binding, Competitive - drug effects | Adenosine A2 Receptor Antagonists - pharmacology | Animals | Adenosine A1 Receptor Agonists - metabolism | Adenosine A3 Receptor Antagonists - metabolism | Mice | Receptors, Purinergic P1 - metabolism | Receptors, Purinergic P1 - drug effects | Adenosine | Original
Journal Article
Purinergic Signalling, ISSN 1573-9538, 9/2012, Volume 8, Issue 3, pp. 419 - 436
The medicinal chemistry and pharmacology of the four subtypes of adenosine receptors (ARs) and the eight subtypes of P2Y receptors (P2YRs, activated by a range... 
Clinical trials, nucleosides | Neurosciences | Adenosine receptors | Human Physiology | P2Y receptors | Antagonists | Nucleotides | Biomedicine general | Biomedicine | GPCR structure | Cancer Research | Agonists | Pharmacology/Toxicology | PHYLOGENETIC ANALYSIS | A(2B) ADENOSINE | ANTAGONIST RECOGNITION | SITE-DIRECTED MUTAGENESIS | MUTATIONAL ANALYSIS | NEUROSCIENCES | NUCLEOTIDE RECEPTORS | INTERNATIONAL UNION | SUBTYPE SELECTIVITY | MOLECULAR RECOGNITION | PURINERGIC RECEPTORS | Receptors, G-Protein-Coupled - metabolism | Humans | Purinergic P2Y Receptor Agonists - therapeutic use | Purinergic P1 Receptor Agonists - therapeutic use | Purinergic P1 Receptor Antagonists - pharmacology | Receptors, Purinergic P1 - chemistry | Receptors, Purinergic P2 - chemistry | Drug Design | Receptors, G-Protein-Coupled - drug effects | Purinergic P2Y Receptor Antagonists - therapeutic use | Purinergic P2Y Receptor Antagonists - pharmacology | Purinergic P1 Receptor Agonists - chemistry | Purinergic P1 Receptor Agonists - pharmacology | Purinergic P1 Receptor Antagonists - therapeutic use | Purinergic P2Y Receptor Agonists - chemistry | Clinical Trials as Topic | Receptors, Purinergic P2 - drug effects | Purinergic P2Y Receptor Agonists - pharmacology | Animals | Purinergic P2Y Receptor Antagonists - chemistry | Receptors, Purinergic P2 - metabolism | Ligands | Receptors, Purinergic P1 - metabolism | Receptors, Purinergic P1 - drug effects | Receptors, G-Protein-Coupled - chemistry | Purinergic P1 Receptor Antagonists - chemistry | Glaucoma | Heart | Adenosine | Parkinson's disease | Psoriasis | Cystic fibrosis | Rheumatoid factor | Hepatitis | Alkaloids | Pyrimidines | Heterocyclic compounds | Emissions (Pollution) | Rheumatoid arthritis | Respiratory tract diseases | Eye diseases | G proteins | Diabetes | Ophthalmology | Kidney diseases | Hepatitis C | DNA-ligand interactions | Arrhythmia | Clinical trials | Ionizing radiation | Reperfusion | Ischemia | pyrimidines | Injuries | Movement disorders | Neurodegenerative diseases | Diabetes mellitus | Lung diseases | Pharmacology | Thrombosis | imaging | Stress | Purine P2Y receptors | purines | Hypoxia | Receptor mechanisms | ATP | Cancer | Pharmaceuticals | Original
Journal Article
Journal of Chemical Information and Modeling, ISSN 1549-9596, 05/2015, Volume 55, Issue 5, pp. 1045 - 1061
The spectacular advances in G-protein-coupled receptor (GPCR) structure determination have opened up new possibilities for structure-based GPCR ligand... 
Adrenergic beta-2 Receptor Antagonists | Humans | Computational Biology | Library and Information Sciences | Chemistry(all) | Crystallography, X-Ray | Receptors, Adrenergic, beta-2 | Adrenergic beta-2 Receptor Agonists | Journal Article | Adrenergic beta-1 Receptor Antagonists | Animals | Computer Science Applications | Research Support, Non-U.S. Gov't | Receptors, Adrenergic, beta-1 | Adrenergic beta-1 Receptor Agonists | Chemical Engineering(all) | Ligands | Protein Conformation | Medicine(all) | Molecular Docking Simulation | Drug Evaluation, Preclinical | CHEMISTRY, MEDICINAL | CRYSTAL-STRUCTURE | COMPUTER SCIENCE, INFORMATION SYSTEMS | HUMAN P2Y RECEPTOR | ADRENERGIC-RECEPTOR | 2 SERINE RESIDUES | CHEMISTRY, MULTIDISCIPLINARY | A(2A) ADENOSINE RECEPTOR | MOLECULAR INTERACTION FINGERPRINTS | MUSCARINIC ACETYLCHOLINE-RECEPTOR | COMPUTER SCIENCE, INTERDISCIPLINARY APPLICATIONS | STRUCTURE-BASED DISCOVERY | BETA-ADRENERGIC RECEPTOR | PARTIAL AGONIST ACTIVITY | Computational Biology - methods | Adrenergic beta-1 Receptor Antagonists - pharmacology | Adrenergic beta-2 Receptor Agonists - metabolism | Receptors, Adrenergic, beta-1 - metabolism | Receptors, Adrenergic, beta-1 - chemistry | Adrenergic beta-1 Receptor Agonists - pharmacology | Receptors, Adrenergic, beta-2 - metabolism | Adrenergic beta-2 Receptor Agonists - pharmacology | Receptors, Adrenergic, beta-2 - chemistry | Adrenergic beta-2 Receptor Antagonists - metabolism | Adrenergic beta-1 Receptor Antagonists - metabolism | Adrenergic beta-1 Receptor Agonists - metabolism | Adrenergic beta-2 Receptor Antagonists - pharmacology
Journal Article
Philosophical Transactions of the Royal Society B: Biological Sciences, ISSN 0962-8436, 08/2016, Volume 371, Issue 1700, pp. 20150427 - 20150427
Journal Article
Brain Research Reviews, ISSN 0165-0173, 2007, Volume 58, Issue 2, pp. 415 - 452
Abstract Future therapies for diseases associated with altered dopaminergic signaling, including Parkinson's disease, schizophrenia and drug addiction or drug... 
Neurology | Treatment strategy | Drug addiction | Galanin receptor | Dopamine receptor | Schizophrenia | Depression | Striatum | 5-HT 1A receptor | CB1 receptor | Heteromerization |