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Biochemical Pharmacology, ISSN 0006-2952, 2011, Volume 82, Issue 4, pp. 358 - 370
We characterize interactions of 21 (M)ANT-nucleotides with mammalian adenylyl cyclases. Through combination of enzymological, fluorescence spectroscopy and... 
Fluorescence spectroscopy | Conformational landscape | Molecular modelling | Adenylyl Cyclase | MANT-nucleotides | ISOFORMS | PROTEIN | DRUG DISCOVERY | EDEMA FACTOR | DIFFERENTIAL INTERACTIONS | SOLUBLE GUANYLYL CYCLASE | INHIBITION | NUCLEOSIDE 5'-TRIPHOSPHATES | BACILLUS-ANTHRACIS | PHARMACOLOGY & PHARMACY | FORSKOLIN ANALOGS | Cell Line | Catalytic Domain | ortho-Aminobenzoates - chemistry | Pyrimidine Nucleotides - chemistry | Guanosine Triphosphate - analogs & derivatives | Models, Molecular | Spectrometry, Fluorescence | Guanosine Triphosphate - metabolism | Structure-Activity Relationship | Adenylyl Cyclases - metabolism | Mammals | Purine Nucleotides - chemistry | Purine Nucleotides - metabolism | Adenosine Triphosphate - analogs & derivatives | Pyrimidine Nucleotides - metabolism | Spodoptera | Animals | Adenosine Triphosphate - metabolism | Guanosine Triphosphate - chemistry | Adenosine Triphosphate - chemistry | ortho-Aminobenzoates - metabolism | Protein Binding - physiology | Fluorescence | Nucleosides | Pyrimidines | Analysis | Pyrimidine nucleotides | Drugs | Enzymes | Landscape | pharmacophores | Adenine | fluorescence spectroscopy | Nucleotides | Xanthine | Structure-activity relationships | Guanine | Adenylate cyclase | Signal transduction | Ribose | Phosphate | purines | Hypoxanthine | Cytosine | pyrimidines | Uracil | Index Medicus | Life Sciences | Pharmacology | Pharmaceutical sciences | conformational landscape | molecular modeling
Journal Article
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 03/2018, Volume 115, Issue 11, p. E2489
Masin et al comment on Gonzalez-Bullon et al's study on phospholipase A (PLA) activity of adenylate cyclase toxin (ACT) purified from recombinant Escherichia... 
Translocation | Enzymes | Adenylate cyclase | Phospholipase | E coli | Calcium | Toxins | Protein transport | Phospholipase A | Contamination | Recombinant
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 2018, Volume 115, Issue 11, pp. E2489 - E2490
Journal Article
Planta Medica, ISSN 0032-0943, 02/2018, Volume 84, Issue 3, pp. 153 - 159
Journal Article
Journal Article
Nature Chemistry, ISSN 1755-4330, 11/2016, Volume 8, Issue 11, pp. 1035 - 1041
Journal Article
JOURNAL OF NEUROSCIENCE, ISSN 0270-6474, 09/2017, Volume 37, Issue 36, pp. 8667 - 8677
Activation of somatic mu-opioid receptors (MORs) in hypothalamic proopiomelanocortin (POMC) neurons leads to the activation of G-protein-coupled inward... 
ATRIAL MYOCYTES | EFFICACY | MORPHINE | TOLERANCE | receptor reserve | action potential | NEUROSCIENCES | DEPENDENCE | RESERVE | electrophysiology | GIRK | POTASSIUM CONDUCTANCE | calcium imaging | HYPOTHALAMIC NEURONS | ADENYLATE-CYCLASE | EXPRESSION | hypothalamus
Journal Article
PLoS ONE, ISSN 1932-6203, 01/2016, Volume 11, Issue 1, p. e0146981
Journal Article
Journal of Molecular and Cellular Cardiology, ISSN 0022-2828, 2012, Volume 56, Issue 1, pp. 129 - 138
Journal Article
Biochemical and Biophysical Research Communications, ISSN 0006-291X, 04/2017, Volume 485, Issue 4, pp. 720 - 724
Proteolytic degradation of the ∼100-kDa isolated RTX (Repeat-in-ToXin) subdomain (CyaA-RTX) of the CyaA-hemolysin (CyaA-Hly) was evidently detected upon... 
Zn2+-metalloproteases | Hydrophobic pore-forming region | Bordetella pertussis | Autocatalysis | Proteolytic degradation | CyaA-RTX | metalloproteases | CELLS | MECHANISM | ACYLATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | ADENYLATE-CYCLASE TOXIN | VIRULENCE | CLOSTRIDIUM-DIFFICILE | BIOPHYSICS | IN-VIVO | BINDING
Journal Article
Neuropharmacology, ISSN 0028-3908, 09/2016, Volume 108, pp. 440 - 450
Journal Article
Journal Article