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Journal Article
Molecular Cell, ISSN 1097-2765, 12/2016, Volume 64, Issue 6, pp. 1109 - 1116
The discovery and study of toxin-antitoxin (TA) systems helps us advance our understanding of the strategies prokaryotes employ to regulate cellular processes... 
NAD | toxin | DarTG | DUF | antitoxin | DNA damage | macrodomain | persistence | PARP | ADP-ribosylation | CELLS | BACTERIA | PERSISTENCE | BIOCHEMISTRY & MOLECULAR BIOLOGY | GENES | BIOFILM | STRESS | CELL BIOLOGY | Substrate Specificity | Crystallography, X-Ray | Antitoxins - chemistry | Bacterial Toxins - antagonists & inhibitors | DNA, Single-Stranded - genetics | Mycobacterium tuberculosis - pathogenicity | Cloning, Molecular | Escherichia coli - metabolism | Bacterial Toxins - genetics | Protein Interaction Domains and Motifs | ADP Ribose Transferases - antagonists & inhibitors | Antitoxins - metabolism | Binding Sites | Mycobacterium tuberculosis - metabolism | Antitoxins - genetics | ADP Ribose Transferases - chemistry | ADP Ribose Transferases - metabolism | Thymidine - metabolism | Recombinant Proteins - metabolism | Gene Expression | Protein Structure, Secondary | DNA, Single-Stranded - metabolism | Models, Molecular | Recombinant Proteins - chemistry | Recombinant Proteins - genetics | Bacterial Toxins - chemistry | DNA, Single-Stranded - chemistry | Amino Acid Motifs | ADP Ribose Transferases - genetics | Bacterial Toxins - metabolism | Escherichia coli - genetics | Protein Binding | Adenosine Diphosphate - metabolism | Mycobacterium tuberculosis - genetics | Enzymes | Biological products | Tuberculosis | Cell death | DNA | Genetic research | Bacteria | Index Medicus | Short
Journal Article
Journal Article
Journal Article
Journal Article
Biochemical Journal, ISSN 0264-6021, 04/2016, Volume 473, Issue 7, pp. 899 - 910
Journal Article
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 6/2014, Volume 111, Issue 23, pp. 8577 - 8582
Immune responses can make protein therapeutics ineffective or even dangerous. We describe a general computational protein design method for reducing... 
T lymphocytes | Immune response | Immunodominant epitopes | Exotoxins | Medical treatment | Alleles | T lymphocyte epitopes | Epitopes | Genetic mutation | Epics | Biotherapeutics | Immunotoxin | Deimmunization | Machine learning | Rosetta | biotherapeutics | MULTIDISCIPLINARY SCIENCES | ANTIBODY | deimmunization | ALGORITHMS | machine learning | IDENTIFICATION | GREEN FLUORESCENT PROTEIN | REDUCED IMMUNOGENICITY | THERAPEUTIC PROTEINS | immunotoxin | OPTIMIZATION | PHASE-I | Virulence Factors - genetics | Protein Engineering - methods | Humans | Molecular Sequence Data | Epitopes, T-Lymphocyte - genetics | Green Fluorescent Proteins - genetics | Virulence Factors - immunology | HLA Antigens - genetics | Support Vector Machine | Flow Cytometry | Bacterial Toxins - genetics | Immunotoxins - chemistry | Epitopes, T-Lymphocyte - immunology | Green Fluorescent Proteins - chemistry | ADP Ribose Transferases - chemistry | Protein Structure, Tertiary | ADP Ribose Transferases - immunology | Immunization | Immunotoxins - immunology | Exotoxins - chemistry | Bacterial Toxins - immunology | Exotoxins - immunology | Mice, Inbred C57BL | HLA Antigens - immunology | Models, Molecular | Spectrometry, Fluorescence | Virulence Factors - chemistry | Bacterial Toxins - chemistry | Proteins - immunology | Proteins - genetics | Sequence Homology, Amino Acid | ADP Ribose Transferases - genetics | Immunotoxins - genetics | Animals | Green Fluorescent Proteins - immunology | Exotoxins - genetics | Cell Line, Tumor | Mice | Computer-Aided Design | Proteins - chemistry | Microbiological research | Protein research | Peptides | Research | Pseudomonas | T cells | Health aspects | Proteins | Bacteria | T cell receptors | Index Medicus | Biological Sciences | Physical Sciences
Journal Article
Structure, ISSN 0969-2126, 03/2013, Volume 21, Issue 3, pp. 462 - 475
Journal Article
Journal Article