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Journal Article
Nature, ISSN 0028-0836, 05/2016, Volume 533, Issue 7601, pp. 120 - 124
Journal Article
Molecular Cell, ISSN 1097-2765, 12/2016, Volume 64, Issue 6, pp. 1109 - 1116
The discovery and study of toxin-antitoxin (TA) systems helps us advance our understanding of the strategies prokaryotes employ to regulate cellular processes... 
NAD | toxin | DarTG | DUF | antitoxin | DNA damage | macrodomain | persistence | PARP | ADP-ribosylation | CELLS | BACTERIA | PERSISTENCE | BIOCHEMISTRY & MOLECULAR BIOLOGY | GENES | BIOFILM | STRESS | CELL BIOLOGY | Substrate Specificity | Crystallography, X-Ray | Antitoxins - chemistry | Bacterial Toxins - antagonists & inhibitors | DNA, Single-Stranded - genetics | Mycobacterium tuberculosis - pathogenicity | Cloning, Molecular | Escherichia coli - metabolism | Bacterial Toxins - genetics | Protein Interaction Domains and Motifs | ADP Ribose Transferases - antagonists & inhibitors | Antitoxins - metabolism | Binding Sites | Mycobacterium tuberculosis - metabolism | Antitoxins - genetics | ADP Ribose Transferases - chemistry | ADP Ribose Transferases - metabolism | Thymidine - metabolism | Recombinant Proteins - metabolism | Gene Expression | Protein Structure, Secondary | DNA, Single-Stranded - metabolism | Models, Molecular | Recombinant Proteins - chemistry | Recombinant Proteins - genetics | Bacterial Toxins - chemistry | DNA, Single-Stranded - chemistry | Amino Acid Motifs | ADP Ribose Transferases - genetics | Bacterial Toxins - metabolism | Escherichia coli - genetics | Protein Binding | Adenosine Diphosphate - metabolism | Mycobacterium tuberculosis - genetics | Enzymes | Biological products | Tuberculosis | Cell death | DNA | Genetic research | Bacteria | Index Medicus | Short
Journal Article
Science, ISSN 0036-8075, 11/2009, Volume 326, Issue 5957, pp. 1231 - 1235
Loss-of-function genetic screens in model organisms have elucidated numerous biological processes, but the diploid genome of mammalian cells has precluded... 
Haploidy | B lymphocytes | Genes | Cell lines | Medical genetics | Cell cycle | HeLa cells | Toxins | Genetic screening | Human genetics | Research Article | TARGET | PROTEIN | ADP-RIBOSYLATING TOXINS | DIPHTHAMIDE | BIOSYNTHESIS | MULTIDISCIPLINARY SCIENCES | INFLUENZA | RECEPTOR | IDENTIFICATION | SACCHAROMYCES-CEREVISIAE | DIPHTHERIA-TOXIN | ADP Ribose Transferases - toxicity | Histidine - analogs & derivatives | Genetic Testing | Humans | N-Acylneuraminate Cytidylyltransferase - genetics | Adenosine Diphosphate Ribose - metabolism | Bacterial Toxins - toxicity | Molecular Sequence Data | Diphtheria Toxin - toxicity | N-Acylneuraminate Cytidylyltransferase - metabolism | Exotoxins - metabolism | Antigens, Bacterial - toxicity | Monosaccharide Transport Proteins - metabolism | ADP Ribose Transferases - metabolism | Monosaccharide Transport Proteins - genetics | Virulence Factors - toxicity | Amino Acid Sequence | Histidine - biosynthesis | Influenza A Virus, H1N1 Subtype - pathogenicity | Biosynthetic Pathways | Diphtheria Toxin - metabolism | Host-Pathogen Interactions | Proteins - genetics | Bacterial Toxins - metabolism | Proteins - metabolism | Cell Line, Tumor | Exotoxins - toxicity | Virulence Factors - metabolism | Mutagenesis, Insertional | Proteins - chemistry | Antigens, Bacterial - metabolism | Peptide Elongation Factor 2 - metabolism | Research | Mutagenesis | Methods | Testing | Models | Cellular biology | Medical screening | Genomics | Influenza | Index Medicus
Journal Article
The FEBS Journal, ISSN 1742-464X, 09/2016, Volume 283, Issue 18, pp. 3371 - 3388
ADP ‐ribosylation is a conserved post‐translational protein modification that plays a role in all major cellular processes, particularly DNA repair,... 
PAR | protein | ribosylation | poly | ribose | ENPP | mass spectrometry | PARP | phosphodiesterase | ADP | post‐translational modification | Post-translational modification | Protein ADP-ribosylation | PARP1 | Poly(ADP-ribose) | ENPP1 | Mass spectrometry | Phosphodiesterase | protein ADP-ribosylation | poly(ADP-ribose) | post-translational modification | CELLS | BIOCHEMISTRY & MOLECULAR BIOLOGY | NUDIX HYDROLASES | RIBOSE | BONE MINERALIZATION | SPINDLE STRUCTURE | NUCLEOTIDE PYROPHOSPHATASES/PHOSPHODIESTERASES | POLY(ADP-RIBOSE) GLYCOHYDROLASE | CELLULAR FUNCTIONS | PURIFICATION | EXPRESSION | Humans | Adenosine Diphosphate Ribose - metabolism | Pyrophosphatases - genetics | Proto-Oncogene Proteins - chemistry | Tandem Mass Spectrometry | Protein Domains | Poly(ADP-ribose) Polymerases - chemistry | Binding Sites | ADP Ribose Transferases - metabolism | Proto-Oncogene Proteins - metabolism | Recombinant Proteins - metabolism | Amino Acid Sequence | Phosphoric Diester Hydrolases - metabolism | Recombinant Proteins - chemistry | Poly (ADP-Ribose) Polymerase-1 - metabolism | Proto-Oncogene Proteins - genetics | Phosphoric Diester Hydrolases - genetics | Pyrophosphatases - chemistry | Recombinant Proteins - genetics | Phosphoric Diester Hydrolases - chemistry | Pyrophosphatases - metabolism | Sequence Homology, Amino Acid | Poly(ADP-ribose) Polymerases - metabolism | Animals | Poly(ADP-ribose) Polymerases - genetics | Poly (ADP-Ribose) Polymerase-1 - chemistry | Mice | Protein Processing, Post-Translational | In Vitro Techniques | Poly (ADP-Ribose) Polymerase-1 - genetics | Phosphates | Enzymes | Nervous system diseases | Physiological aspects | Sugars | Protein binding | Monosaccharides | Proteins | Molecular biology | Index Medicus | poly(ADP‐ribose) | protein ADP‐ribosylation | Original
Journal Article
Journal Article
Journal of the American Chemical Society, ISSN 0002-7863, 04/2014, Volume 136, Issue 14, pp. 5201 - 5204
Adenosine diphosphate ribosyltransferases (ARTDs; ARTD1-17 in humans) are emerging as critical regulators of cell function in both normal physiology and... 
NAD | GENOTOXIC STRESS | POLY(ADP-RIBOSE) POLYMERASE-1 | MICE | BINDING | CHEMISTRY, MULTIDISCIPLINARY | PARP INHIBITOR | Models, Molecular | Substrate Specificity | Humans | Protein Engineering | ADP Ribose Transferases - chemistry | ADP Ribose Transferases - metabolism | Adenosine diphosphate | Protein engineering | Usage | Research | Mass spectrometry | Index Medicus
Journal Article
PLoS Pathogens, ISSN 1553-7366, 10/2009, Volume 5, Issue 10, pp. e1000626 - e1000626
Journal Article
Journal Article
Journal Article