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International Journal of Molecular Sciences, ISSN 1661-6596, 11/2016, Volume 17, Issue 11, pp. 1869 - 1869
Tumor necrosis factor receptor-associated factor 2 (TRAF2) is a critical mediator of tumor necrosis factor-alpha (TNF-alpha) signaling. However, the regulatory... 
TRAF2 | JNK | Tumor necrosis factor-α (TNF-α) | BIG1 | Apoptosis | APOPTOSIS | LOCALIZATION | ACTIVATION | PROTEIN | NECROPTOSIS | BIOCHEMISTRY & MOLECULAR BIOLOGY | tumor necrosis factor-alpha (TNF-alpha); apoptosis | CHEMISTRY, MULTIDISCIPLINARY | CELL-DEATH | ADP-RIBOSYLATION FACTORS | RECYCLING ENDOSOMES | ARF-FAMILY | NF-KAPPA-B | RNA, Small Interfering - genetics | Luciferases - metabolism | Apoptosis - drug effects | Humans | TNF Receptor-Associated Factor 2 - genetics | JNK Mitogen-Activated Protein Kinases - metabolism | NF-kappa B - metabolism | Receptors, Tumor Necrosis Factor, Type I - metabolism | Luciferases - genetics | Proteolysis - drug effects | Ubiquitination - drug effects | Guanine Nucleotide Exchange Factors - metabolism | JNK Mitogen-Activated Protein Kinases - genetics | Genes, Reporter | Guanine Nucleotide Exchange Factors - genetics | NF-kappa B - antagonists & inhibitors | JNK Mitogen-Activated Protein Kinases - antagonists & inhibitors | Gene Expression Regulation | TNF Receptor-Associated Factor 2 - metabolism | Signal Transduction - genetics | Receptors, Tumor Necrosis Factor, Type I - antagonists & inhibitors | Receptors, Tumor Necrosis Factor, Type I - genetics | Protein Transport | TNF Receptor-Associated Factor 2 - antagonists & inhibitors | Tumor Necrosis Factor-alpha - pharmacology | Guanine Nucleotide Exchange Factors - antagonists & inhibitors | NF-kappa B - genetics | Cell Line, Tumor | Protein Binding | HeLa Cells | RNA, Small Interfering - metabolism | Signal transduction | Tumor necrosis factor-TNF | Adenosine triphosphatase | apoptosis | tumor necrosis factor-α (TNF-α)
Journal Article
EMBO Molecular Medicine, ISSN 1757-4676, 01/2011, Volume 3, Issue 1, pp. 21 - 34
The forkhead box M1b (FoxM1b) transcription factor is over‐expressed in human cancers, and its expression often correlates with poor prognosis. Previously,... 
Arf | metastasis | FoxM1 | Metastasis | LYSYL OXIDASE | GLIOMA-CELLS | MEDICINE, RESEARCH & EXPERIMENTAL | CANCER | EPITHELIAL-MESENCHYMAL TRANSITION | HEPATOCELLULAR-CARCINOMA | PATHWAY | TRANSCRIPTION FACTOR | PROMOTES | EXPRESSION | PROGRESSION | Humans | Carcinoma, Hepatocellular - secondary | Neoplasm Metastasis | Forkhead Transcription Factors - metabolism | Epithelial-Mesenchymal Transition | Liver Cirrhosis - metabolism | Liver Neoplasms - pathology | ADP-Ribosylation Factors - metabolism | Forkhead Transcription Factors - antagonists & inhibitors | Proto-Oncogene Proteins c-akt - metabolism | ADP-Ribosylation Factors - genetics | Snail Family Transcription Factors | Signal Transduction | Mice, Transgenic | Forkhead Transcription Factors - genetics | Transcription Factors - metabolism | Animals | Carcinoma, Hepatocellular - pathology | Liver Neoplasms - metabolism | Protein-Lysine 6-Oxidase - metabolism | Liver Cirrhosis - pathology | Mice | Forkhead Box Protein M1 | Stathmin - metabolism | Carcinoma, Hepatocellular - metabolism | Transcription factors | Mesenchyme | Peptides | Hepatocellular carcinoma | AKT protein | Gene expression | Lysyl oxidase | Experiments | Cell adhesion & migration | Metastases | Stathmin | Liver cancer | Lungs | Plasmids | Collagen | Fibrosis | Cell cycle | Forkhead protein | Tumors
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 8/2014, Volume 111, Issue 34, pp. 12378 - 12383
Guanine nucleotide exchange factors (GEFs) of the exchange factor for Arf6 (EFA6), brefeldin A-resistant Arf guanine nucleotide exchange factor (BRAG), and... 
Negative feedback | Guanine nucleotide exchange factors | Control loops | Nuclear membrane | Lipids | Cell membranes | Liposomes | Nucleotides | Kinetics | Positive feedback | Membrane traffic | Endocytosis | Autoinhibition | PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE | POSITIVE FEEDBACK | MEMBRANE | MULTIDISCIPLINARY SCIENCES | G-PROTEINS | PH DOMAIN | autoinhibition | membrane traffic | FAMILY | STRUCTURAL BASIS | NUCLEOTIDE EXCHANGE FACTOR | endocytosis | kinetics | BINDING | CONFORMATIONAL SWITCH | Cell Adhesion Molecules - chemistry | Cell Adhesion Molecules - genetics | Membrane Glycoproteins - metabolism | Humans | Membrane Glycoproteins - chemistry | Guanosine Triphosphate - metabolism | Nerve Tissue Proteins - chemistry | Guanine Nucleotide Exchange Factors - metabolism | ADP-Ribosylation Factor 1 - metabolism | Sulfotransferases - metabolism | Protein Interaction Domains and Motifs | ADP-Ribosylation Factor 1 - genetics | ADP-Ribosylation Factors - metabolism | Guanosine Diphosphate - metabolism | ADP-Ribosylation Factors - genetics | Recombinant Proteins - metabolism | Sulfotransferases - genetics | Cell Line | Cricetinae | Guanine Nucleotide Exchange Factors - genetics | Mutagenesis, Site-Directed | Recombinant Proteins - chemistry | Recombinant Proteins - genetics | Cell Adhesion Molecules - metabolism | Nerve Tissue Proteins - genetics | Membrane Glycoproteins - genetics | Nerve Tissue Proteins - metabolism | ADP-Ribosylation Factors - chemistry | Feedback, Physiological | Animals | Models, Biological | Enzyme Activation | ADP-Ribosylation Factor 1 - chemistry | Sulfotransferases - chemistry | Amino Acid Substitution | Guanine Nucleotide Exchange Factors - chemistry | Physiological aspects | Protein research | Research | Guanosine triphosphatase | Protein-protein interactions | Membrane proteins | Biological Sciences
Journal Article
The Plant cell, ISSN 1040-4651, 10/2018, Volume 30, Issue 10, pp. 2553 - 2572
The trafficking of subcellular cargos in eukaryotic cells crucially depends on vesicle budding, a process mediated by ARFGEFs (ADP-ribosylation factor guanine... 
ARABIDOPSIS-THALIANA | GUANINE-NUCLEOTIDE-EXCHANGE | ROOT GRAVITROPISM | BIOCHEMISTRY & MOLECULAR BIOLOGY | ADP-RIBOSYLATION FACTOR-1 | AUXIN EFFLUX CARRIER | PLANT SCIENCES | CELL BIOLOGY | INDUCED HAPLOINSUFFICIENCY | TRANS-GOLGI NETWORK | ENDOPLASMIC-RETICULUM | BREFELDIN-A | YEAST GOLGI
Journal Article