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Bioorganic & Medicinal Chemistry, ISSN 0968-0896, 07/2018, Volume 26, Issue 12, pp. 3502 - 3513
(+)-Cyclazosin is one of most selective antagonists of the α -adrenoceptor subtype (selectivity ratios, α /α  = 13, α /α  = 38–39). To improve the selectivity,... 
(+)-Cyclazosin analogues | α1-Adrenoceptor subtypes | α1-Adrenoceptor antagonists | α1B-Adrenoceptor selective antagonists | Adrenoceptor selective antagonists | α | Adrenoceptor antagonists | Adrenoceptor subtypes | (+)-cyclazosin analogues | α1-adrenoceptor subtypes | α1-adrenoceptor antagonists | α1B-adrenoceptor selective antagonists
Journal Article
Journal Article
British Journal of Pharmacology, ISSN 0007-1188, 02/2006, Volume 147, Issue 2, pp. S88 - S119
Journal Article
British Journal of Pharmacology, ISSN 0007-1188, 05/2011, Volume 163, Issue 1, pp. 4 - 17
Journal Article
British Journal of Pharmacology, ISSN 0007-1188, 09/2002, Volume 137, Issue 1, pp. 9 - 18
Journal Article
Journal Article
CELL METABOLISM, ISSN 1550-4131, 01/2015, Volume 21, Issue 1, pp. 33 - 38
Increasing energy expenditure through activation of endogenous brown adipose tissue (BAT) is a potential approach to treat obesity and diabetes. The class of... 
SELECTIVE BETA-ADRENOCEPTOR AGONIST | THERMOGENESIS | ADRENOCEPTOR AGONIST | ENERGY-EXPENDITURE | COLD-EXPOSURE | METABOLISM | MIRABEGRON | ENDOCRINOLOGY & METABOLISM | DOUBLE-BLIND | FAT | ADULT HUMANS | CELL BIOLOGY
Journal Article
Journal of Pharmacological Sciences, ISSN 1347-8613, 08/2018, Volume 137, Issue 4, pp. 366 - 371
α -adrenoceptor antagonists can impact upon sexual function and have potential in the treatment of erectile dysfunction. Human erectile tissue contains... 
Prazosin | Tamsulosin | α1-adrenoceptor subtypes | α1L-adrenoceptor | Erectile tissue | adrenoceptor | adrenoceptor subtypes
Journal Article
European Journal of Pharmacology, ISSN 0014-2999, 11/2018, Volume 838, pp. 120 - 128
Cutaneous arteries show enhanced contraction in response to cooling, which is suggested to be mediated via α -adrenoceptors. We have previously shown that α... 
α1A-adrenoceptor | Cooling | Cutaneous artery | Voltage-dependent calcium channel | α1D-adrenoceptor | adrenoceptor
Journal Article
Naunyn-Schmiedeberg's Archives of Pharmacology, ISSN 0028-1298, 6/2008, Volume 377, Issue 4, pp. 473 - 481
Journal Article
British Journal of Pharmacology, ISSN 0007-1188, 02/2010, Volume 159, Issue 4, pp. 787 - 796
Background and purpose:  Pharmacological analysis of synergism or functional antagonism between different receptors commonly assumes that interacting receptors... 
fluorescent ligand binding | endothelium | adrenoceptor | vascular smooth muscle | adventitia | confocal microscopy | cannabinoid | angiotensin | α1B/D-adrenoceptor knockout | α1B/D‐adrenoceptor knockout | Adventitia | adrenoceptor knockout | Fluorescent ligand binding | Angiotensin | Confocal microscopy | Vascular smooth muscle | Cannabinoid | Adrenoceptor | Endothelium | MESENTERIC-ARTERIES | SUBTYPES | ANANDAMIDE | GPR55 | SURFACE EXPRESSION | ANGIOTENSIN-II | ALPHA(1D)-ADRENERGIC RECEPTORS | alpha(1B/D)-adrenoceptor knockout | PHARMACOLOGY | CARDIOVASCULAR-DISEASE | PHARMACOLOGY & PHARMACY | SMOOTH-MUSCLE-CELLS | Receptors, Adrenergic, alpha-1 - metabolism | Molecular Probe Techniques | Propanolamines - metabolism | Muscle, Smooth, Vascular - metabolism | Rats, Wistar | Fluorescent Dyes - metabolism | Prazosin - metabolism | Male | Molecular Imaging | Prazosin - analogs & derivatives | Receptors, Cannabinoid - metabolism | Receptors, Adrenergic - genetics | Tail - blood supply | Receptors, Adrenergic, beta - metabolism | Mesenteric Arteries - cytology | Boron Compounds - metabolism | Angiotensin II - metabolism | Receptors, Adrenergic - metabolism | Mice, Inbred C57BL | Rats | Pyrazoles - metabolism | Mesenteric Arteries - metabolism | Connective Tissue - metabolism | Mice, Knockout | Receptors, Adrenergic - deficiency | Microscopy, Confocal | Animals | Endothelium, Vascular - metabolism | Ligands | Mice | Localization | Rodents | Veins & arteries | Research Papers | Themed Section | D-adrenoceptor knockout | α1B
Journal Article
European Journal of Pharmacology, ISSN 0014-2999, 11/2018, Volume 839, pp. 82 - 88
Modulation of cardiac contractility by α-adrenoceptor is well known in several mammals. Mice are useful experimental animals, but α-adrenoceptor-mediated... 
α1B-adrenoceptor | Chronotropic action | α1-adrenoceptor | Mouse atrium | Inotropic action | adrenoceptor
Journal Article
CELLULAR AND MOLECULAR LIFE SCIENCES, ISSN 1420-682X, 02/2010, Volume 67, Issue 3, pp. 405 - 417
Journal Article
BEHAVIOURAL PHARMACOLOGY, ISSN 0955-8810, 02/2015, Volume 26, Issue 1-2, pp. 73 - 80
Intra-accumbal infusion of the alpha(1)-adrenergic agonist methoxamine, which has comparable affinity for alpha(1A)-, alpha(1B)- and alpha(1D)-adrenoceptor... 
rat | alpha(1A)-adrenoceptor | PRAZOSIN | ALPHA(1B)-ADRENOCEPTOR ANTAGONIST | ALPHA-ADRENOCEPTOR SUBTYPES | alpha(1B)-adrenoceptor | nucleus accumbens | alpha(1D)-adrenoceptor | AGONISTS | NEUROSCIENCES | RECEPTOR SUBTYPES | PROFILE | microdialysis | ADRENOCEPTORS | LOCUS-COERULEUS | NEURONS | BEHAVIORAL SCIENCES | PHARMACOLOGY & PHARMACY | dopamine
Journal Article
Journal Article