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Hypertension (Dallas, Tex. : 1979), ISSN 0194-911X, 9/2016, Volume 68, Issue 3, pp. 785 - 795
Aldosterone, which plays a key role in maintaining water and electrolyte balance, is produced by zona glomerulosa cells of the adrenal cortex. Autonomous... 
SK channels | Primary hyperaldosteronism | aldosterone secretion | apamin | adrenocortical cells
Journal Article
Journal Article
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, ISSN 0021-972X, 01/2012, Volume 97, Issue 1, pp. 100 - 109
Context: Identification of unilateral aldosterone-producing (Conn's) adenomas has traditionally required lateralization by the invasive and technically... 
HUMAN ADRENOCORTICAL-CELLS | PRIMARY HYPERALDOSTERONISM | DIAGNOSIS | DEXAMETHASONE-SUPPRESSION | RESPONSE PATHWAY | 11-BETA-HYDROXYLASE TRACER C-11-METOMIDATE | CLINICAL DECISION-MAKING | ENDOCRINOLOGY & METABOLISM | BIOCHEMICAL SUCCESS | ADRENAL INCIDENTALOMAS | HYPERTENSIVE PATIENTS
Journal Article
Science, ISSN 0036-8075, 2/2011, Volume 331, Issue 6018, pp. 768 - 772
Endocrine tumors such as aldosterone-producing adrenal adenomas (APAs), a cause of severe hypertension, feature constitutive hormone production and... 
Depolarization | Hypertension | Somatic mutation | Cell growth | Hyperaldosteronism | REPORTS | Loss of heterozygosity | Adenoma | Genetic mutation | Sequencing | Tumors | REMEDIABLE ALDOSTERONISM | HUMAN BREAST | COLORECTAL CANCERS | ADRENOCORTICAL-CELLS | MULTIDISCIPLINARY SCIENCES | CONDUCTION | GLOMERULOSA CELLS | IDENTIFICATION | MOLECULAR-BASIS | SELECTIVITY | POTASSIUM CHANNEL | Adrenal Glands - pathology | Potassium - metabolism | Cell Proliferation | Humans | Hyperaldosteronism - pathology | Hyperplasia | Protein Multimerization | Zona Glomerulosa - pathology | Male | Hyperaldosteronism - metabolism | Sodium - metabolism | Aldosterone - metabolism | Adrenocortical Adenoma - genetics | G Protein-Coupled Inwardly-Rectifying Potassium Channels - metabolism | Female | Hypertension - genetics | Adrenal Cortex Neoplasms - metabolism | Cell Line | G Protein-Coupled Inwardly-Rectifying Potassium Channels - chemistry | Hyperaldosteronism - genetics | Mutant Proteins - genetics | Mutant Proteins - metabolism | Zona Glomerulosa - metabolism | Adrenal Cortex Neoplasms - pathology | G Protein-Coupled Inwardly-Rectifying Potassium Channels - genetics | Adrenocortical Adenoma - pathology | Adrenocortical Adenoma - metabolism | Hypertension - metabolism | Adrenal Cortex Neoplasms - genetics | Mutant Proteins - chemistry | Mutation | Medical and Health Sciences | MEDICINE | Medicin och hälsovetenskap | MEDICIN
Journal Article
The Journal of Clinical Endocrinology & Metabolism, ISSN 0021-972X, 10/2018, Volume 103, Issue 10, pp. 3737 - 3747
Context: The aberrant expression or alternation of miRNA in the pathogenesis of aldosterone-producing adenomas (APAs) is still largely unknown. Objective: We... 
STEROIDOGENESIS | CANCER CELLS | GENE | CHANNELOPATHY | ADRENOCORTICAL-CELLS | SIGNALING PATHWAY | GROWTH | ENDOCRINOLOGY & METABOLISM | MICRORNAS | WNT-5A | EXPRESSION
Journal Article