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CELL, ISSN 0092-8674, 02/2005, Volume 120, Issue 4, pp. 449 - 460
Mutations in genes affecting endocrine signaling, stress responses, metabolism, and telomeres can all increase the life spans of model organisms. These... 
LIFE-SPAN EXTENSION | FORKHEAD TRANSCRIPTION FACTOR | FACTOR-I LEVELS | HEAT-SHOCK FACTOR | SIGNALING PATHWAY | BIOCHEMISTRY & MOLECULAR BIOLOGY | INSULIN-RECEPTOR SUBSTRATE | C-ELEGANS | NEMATODE CAENORHABDITIS-ELEGANS | ADULT DROSOPHILA-MELANOGASTER | AGE-1 PI3 KINASE | CELL BIOLOGY
Journal Article
PLOS GENETICS, ISSN 1553-7404, 05/2017, Volume 13, Issue 5
Activation of the FOXO transcription factor DAF-16 by reduced insulin/IGF signaling (IIS) is considered to be beneficial in C. elegans due to its ability to... 
INSULIN | LIFE-SPAN | LONGEVITY | CAENORHABDITIS-ELEGANS | BODY-SIZE | STRESS-RESPONSE | GENETICS & HEREDITY | LARVAL DEVELOPMENT | MYELOID-LEUKEMIA | TRANSCRIPTION FACTOR | AGE-1 PI3 KINASE
Journal Article
Genes and Development, ISSN 0890-9369, 07/2005, Volume 19, Issue 13, pp. 1544 - 1555
Journal Article
Genes and Development, ISSN 0890-9369, 02/2009, Volume 23, Issue 4, pp. 496 - 511
Rictor is a component of the target of rapamycin complex 2 (TORC2). While TORC2 has been implicated in insulin and other growth factor signaling pathways, the... 
AKT | Fat metabolism | C. Elegans | Life span | Insulin/IGF | NERVOUS-SYSTEM | C. elegans | AKT/PKB | life span | DEVELOPMENTAL BIOLOGY | AGE-1 PI3 KINASE | CELL BIOLOGY | INSULIN | RAPTOR | MTOR COMPLEX-2 | LONGEVITY | SIGNALING PATHWAY | insulin/IGF | GENETICS & HEREDITY | C-ELEGANS | fat metabolism | TRANSCRIPTION FACTOR | Caenorhabditis elegans Proteins - metabolism | Reproduction - physiology | Fixatives - metabolism | Intestines - metabolism | Adipose Tissue - metabolism | Caenorhabditis elegans - physiology | Immediate-Early Proteins - metabolism | Oxazines - metabolism | Oncogene Protein v-akt - metabolism | Protein-Serine-Threonine Kinases - metabolism | Somatomedins - metabolism | Rapamycin-Insensitive Companion of mTOR Protein | Boron Compounds - metabolism | Caenorhabditis elegans - metabolism | Caenorhabditis elegans - growth & development | Signal Transduction | Caenorhabditis elegans - genetics | Mutation - genetics | Feeding Behavior - physiology | Carrier Proteins - genetics | Adaptor Proteins, Signal Transducing | Insulin - metabolism | Animals | Carrier Proteins - metabolism | Diet | Caenorhabditis elegans Proteins - genetics | Longevity - physiology | Lipid Metabolism - physiology | Life spans (Biology) | Caenorhabditis elegans | Immune response | Physiological aspects | Genetic aspects | Rapamycin | Research | insulin | IGF | Research Paper
Journal Article
Journal Article
Journal Article
Cell Death and Differentiation, ISSN 1350-9047, 07/2016, Volume 23, Issue 7, pp. 1110 - 1118
Journal Article