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1. Full Text Multisensory decision-making in rats and humans
by Raposo, David and Sheppard, John P and Schrater, Paul R and Churchland, Anne K
Journal of Neuroscience, ISSN 0270-6474, 03/2012, Volume 32, Issue 11, pp. 3726 - 3735
We report a novel multisensory decision task designed to encourage subjects to combine information across both time and sensory modalities. We presented... 
SUPERIOR COLLICULUS | PERCEPTUAL DECISION | TEXTURE | INTEGRATION | INTRAPARIETAL AREA | AUDITORY-CORTEX | PARIETAL CORTEX | CUE COMBINATION | MOTION CUES | NEUROSCIENCES | MACAQUE MONKEY | Visual Perception - physiology | Humans | Middle Aged | Rats, Long-Evans | Rats | Male | Auditory Perception - physiology | Psychomotor Performance - physiology | Acoustic Stimulation - methods | Young Adult | Animals | Photic Stimulation - methods | Time Factors | Adult | Female | Decision Making - physiology | Index Medicus
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2. Full Text The protective effect of dietary eicosapentaenoic acid against impairment of spatial cognition learning ability in rats infused with amyloid β (1–40)
by Hashimoto, Michio and Hossain, Shahdat and Tanabe, Yoko and Kawashima, Akiko and Harada, Tsuyoshi and Yano, Takashi and Mizuguchi, Kiyoshi and Shido, Osamu
The Journal of Nutritional Biochemistry, ISSN 0955-2863, 2009, Volume 20, Issue 12, pp. 965 - 973
Amyloid β (Aβ) peptide (1–40) can cause cognitive impairment. We investigated whether dietary preadministration of eicosapentaenoic acid (EPA) is conducive to... 
Rat | Alzheimer's disease | Fatty acid | Amyloid β | Hippocampus | Spatial memory | ALZHEIMERS-DISEASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | N-3 FATTY-ACIDS | RELEASE | BETA | IN-VITRO | NUTRITION & DIETETICS | Amyloid beta | DOCOSAHEXAENOIC ACID | MOUSE MODEL | CAUDAL ARTERY | AGED RATS | BRAIN | Memory - drug effects | Amyloid beta-Peptides - antagonists & inhibitors | Animals | Rats, Wistar | Peptide Fragments - antagonists & inhibitors | Space Perception - drug effects | Amyloid beta-Peptides - pharmacology | Rats | Male | Peptide Fragments - pharmacology | Eicosapentaenoic Acid - therapeutic use | Maze Learning - drug effects | Index Medicus
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3. Full Text MicroRNA profiles in hippocampal granule cells and plasma of rats with pilocarpine-induced epilepsy - Comparison with human epileptic samples
by Roncon, Paolo and Soukupovà, Marie and Binaschi, Anna and Falcicchia, Chiara and Zucchini, Silvia and Ferracin, Manuela and Langley, Sarah R and Petretto, Enrico and Johnson, Michael R and Marucci, Gianluca and Michelucci, Roberto and Rubboli, Guido and Simonato, Michele
Scientific Reports, ISSN 2045-2322, 09/2015, Volume 5, Issue 1, pp. 14143 - 14143
The identification of biomarkers of the transformation of normal to epileptic tissue would help to stratify patients at risk of epilepsy following brain... 
CIRCULATING MICRORNAS | BIOMARKERS | ISSUES | TEMPORAL-LOBE EPILEPSY | 1ST SPONTANEOUS SEIZURE | MULTIDISCIPLINARY SCIENCES | EXPRESSION PROFILE | GENE-EXPRESSION | MIRNAS | MODEL | LASER MICRODISSECTION | Pyramidal Cells - metabolism | Humans | Middle Aged | Gene Expression Regulation | Transcriptome | Rats | Male | Gene Expression Profiling | Gene Regulatory Networks | Hippocampus - cytology | Case-Control Studies | Hippocampus - metabolism | Animals | Epilepsy - chemically induced | Pilocarpine - adverse effects | Biomarkers | Adult | Epilepsy - genetics | Female | MicroRNAs - blood | MicroRNAs - genetics | Cluster Analysis | Epilepsy - blood | Transformation | Epilepsy | Rodents | Granule cells | MiRNA | Pilocarpine | Hippocampus | Brain injury | Latency | Index Medicus
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4. Full Text Assessment of psychotropic-like properties of a probiotic formulation (Lactobacillus helveticus R0052 and Bifidobacterium longum R0175) in rats and human subjects
by Messaoudi, Michaël and Lalonde, Robert and Violle, Nicolas and Javelot, Hervé and Desor, Didier and Nejdi, Amine and Bisson, Jean-François and Rougeot, Catherine and Pichelin, Matthieu and Cazaubiel, Murielle and Cazaubiel, Jean-Marc
British Journal of Nutrition, ISSN 0007-1145, 3/2011, Volume 105, Issue 5, pp. 755 - 764
In a previous clinical study, a probiotic formulation (PF) consisting of Lactobacillus helveticus R0052 and Bifidobacterium longum R0175 (PF) decreased... 
Coping strategies | Probiotics | Depression | Anxiety | Stress | HOSPITAL ANXIETY | INTESTINAL EPITHELIAL-CELLS | MATERNAL SEPARATION | INTERFERON-ALPHA | NUTRITION & DIETETICS | LIFE STRESS | DISEASE | ANIMAL-MODEL | MAJOR DEPRESSIVE DISORDER | DYSFUNCTION | IRRITABLE-BOWEL-SYNDROME | Anger - drug effects | Rats, Wistar | Humans | Middle Aged | Male | Anxiety - drug therapy | Psychotropic Drugs - therapeutic use | Depression - drug therapy | Psychotropic Drugs - pharmacology | Adult | Female | Hostility | Somatoform Disorders - drug therapy | Anti-Anxiety Agents - therapeutic use | Severity of Illness Index | Bifidobacterium | Lactobacillus helveticus | Double-Blind Method | Stress, Psychological - drug therapy | Adaptation, Psychological - drug effects | Anti-Anxiety Agents - pharmacology | Rats | Probiotics - pharmacology | Animals | Probiotics - therapeutic use | Psychological aspects | Human subjects | Rodents | Index Medicus
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5. Full Text Memory Loss in Old Rats is Associated with Brain Mitochondrial Decay and RNA/DNA Oxidation: Partial Reversal by Feeding Acetyl-L-Carnitine and/or R-α-Lipoic Acid
by Jiankang Liu and Elizabeth Head and Afshin M. Gharib and Wenjun Yuan and Russell T. Ingersoll and Tory M. Hagen and Carl W. Cotman and Bruce N. Ames
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 2/2002, Volume 99, Issue 4, pp. 2356 - 2361
Accumulation of oxidative damage to mitochondria, protein, and nucleic acid in the brain may lead to neuronal and cognitive dysfunction. The effects on... 
Biological Sciences | Mitochondria | RNA | Memory decay | Memory | Rats | Brain damage | Nucleic acids | Behavioral neuroscience | Hippocampus | Flood damage | LONG-TERM-MEMORY | COGNITIVE PERFORMANCE | PROTEIN OXIDATION | ALZHEIMERS-DISEASE | MULTIDISCIPLINARY SCIENCES | MORRIS WATER MAZE | SPATIAL MEMORY | LEVOCARNITINE ACETYL | AGED RATS | METABOLIC ANTIOXIDANT | RNA OXIDATION | Immunohistochemistry | Acetylcarnitine - pharmacology | Age Factors | Oxidative Stress | Rats, Inbred F344 | Male | Thioctic Acid - pharmacology | Mitochondria - metabolism | Antioxidants - pharmacology | DNA - metabolism | Microscopy, Electron | Oxygen - metabolism | Brain - metabolism | Animals | Maze Learning | Time Factors | Brain - pathology | Hippocampus - ultrastructure | Nootropic Agents - pharmacology | Animal Feed | RNA - metabolism | Neurology | Brain | Biochemistry | Rodents | acetylcarnitine | 8-Hydroxy-2'-deoxyguanosine | acetyl-L-carnitine | 8-Hydroxyguanosine | a-Lipoic acid | Index Medicus
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6. Full Text Pharmacokinetics, distribution, and metabolism of [ 14C]sunitinib in rats, monkeys, and humans
by Speed, Bill and Bu, Hai-Zhi and Pool, William F and Peng, Geoffrey W and Wu, Ellen Y and Patyna, Shem and Bello, Carlo and Kang, Ping
Drug Metabolism and Disposition, ISSN 0090-9556, 03/2012, Volume 40, Issue 3, pp. 539 - 555
Sunitinib is an oral multitargeted tyrosine kinase inhibitor approved for the treatment of advanced renal cell carcinoma, imatinib-refractory gastrointestinal... 
CELL LUNG-CANCER | PHASE-II TRIAL | IN-VIVO | TYROSINE KINASE INHIBITOR | SUNITINIB MALATE | PHARMACOLOGY & PHARMACY | GROWTH-FACTOR | SU11248 | Absorption - physiology | Pyrroles - pharmacokinetics | Pyrroles - urine | Humans | Middle Aged | Half-Life | Macaca fascicularis | Biological Availability | Male | Indoles - administration & dosage | Tissue Distribution | Young Adult | Indoles - metabolism | Pyrroles - administration & dosage | Adult | Female | Carbon Isotopes - urine | Pyrroles - metabolism | Administration, Oral | Rats | Carbon Isotopes - metabolism | Rats, Sprague-Dawley | Animals | Feces - chemistry | Indoles - pharmacokinetics | Injections, Intravenous - methods | Carbon Isotopes - administration & dosage | Carbon Radioisotopes | Indoles - urine | Index Medicus
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7. Full Text Direct effects of transcranial electric stimulation on brain circuits in rats and humans
by Vöröslakos, Mihály and Takeuchi, Yuichi and Brinyiczki, Kitti and Zombori, Tamás and Oliva, Azahara and Fernández-Ruiz, Antonio and Kozák, Gábor and Kincses, Zsigmond Tamás and Iványi, Béla and Buzsáki, György and Berényi, Antal
Nature Communications, ISSN 2041-1723, 12/2018, Volume 9, Issue 1, pp. 483 - 17
Transcranial electric stimulation is a non-invasive tool that can influence brain activity; however, the parameters necessary to affect local circuits in vivo... 
FIELDS | EXCITABILITY | SAFETY | MULTIDISCIPLINARY SCIENCES | MOTOR EVOKED-POTENTIALS | IN-VIVO | TDCS | NEURONS | OSCILLATIONS | ALTERNATING-CURRENT STIMULATION | MODULATION | Brain | Neurons | Humans | Middle Aged | Rats, Long-Evans | Rats | Male | Electroencephalography | Healthy Volunteers | Neural Pathways | Young Adult | Patch-Clamp Techniques | Transcranial Direct Current Stimulation | Animals | Adult | Female | Skull | Aged | Cadaver | Charge density | Firing pattern | Circuits | Rodents | EEG | Stimulation | Index Medicus
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8. Full Text Insulin Resistance-Related Proteins Are Overexpressed in Patients and Rats Treated with Olanzapine and Are Reverted by Pueraria in the Rat Model
by Yang, Ni and Li, Shihong and Liu, Shouqing and Lv, Yifan and Yu, Liangyu and Deng, Yahui and Li, Huqun and Fang, Maosheng and Huo, Yunxiang and Li, Weiyong and Peng, Shiyong
Journal of Clinical Psychopharmacology, ISSN 0271-0749, 05/2019, Volume 39, Issue 3, pp. 214 - 219
Background: Olanzapine, a commonly used second-generation antipsychotic, causes severe metabolic adverse effects, such as elevated blood glucose and insulin... 
olanzapine | insulin resistance-related proteins (IRRPs) | schizophrenia | insulin resistance | Pueraria | HOMEOSTASIS | LIPID-METABOLISM | PSYCHIATRY | OBESITY | GRK2 | TYROSINE-PHOSPHATASE 1B | GLUCOSE | PHARMACOLOGY & PHARMACY | CD36 | DYSFUNCTION | EXPRESSION | LOBATA WILLD | Plant Extracts - pharmacology | Antipsychotic Agents - adverse effects | Humans | Middle Aged | Insulin Resistance | Body Weight - drug effects | Rats | Male | Antipsychotic Agents - administration & dosage | Blood Glucose - drug effects | Animals | Time Factors | Adult | Female | Olanzapine - adverse effects | Pueraria - chemistry | Schizophrenia - drug therapy | Olanzapine - administration & dosage | Disease Models, Animal | Usage | Care and treatment | Rats as laboratory animals | Olanzapine | Schizophrenia | Research | Gene expression | Patient compliance | Insulin | Analysis | Dosage and administration | Drug therapy | Health aspects
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9. Full Text Asymmetric dimethylarginine (ADMA) elevation and arginase up‐regulation contribute to endothelial dysfunction related to insulin resistance in rats and morbidly obese humans
by El Assar, Mariam and Angulo, Javier and Santos‐Ruiz, Marta and Ruiz de Adana, Juan Carlos and Pindado, María Luz and Sánchez‐Ferrer, Alberto and Hernández, Alberto and Rodríguez‐Mañas, Leocadio
The Journal of Physiology, ISSN 0022-3751, 06/2016, Volume 594, Issue 11, pp. 3045 - 3060
The presence of insulin resistance (IR) is determinant for endothelial dysfunction associated with obesity. Although recent studies have implicated the... 
SYNTHASE | METFORMIN | OXIDATIVE STRESS | PHYSIOLOGY | DEPENDENT RELAXATION | NITRIC-OXIDE SYNTHESIS | L-ARGININE | CARDIOVASCULAR-DISEASE | SENSITIVITY | NEUROSCIENCES | ENDOGENOUS INHIBITOR | IMPAIRMENT | Humans | Middle Aged | Arginase - metabolism | Endothelium, Vascular - drug effects | Male | Arginine - analogs & derivatives | Dose-Response Relationship, Drug | Adipose Tissue - metabolism | Insulin Resistance - physiology | Up-Regulation - physiology | Adult | Female | Arginase - antagonists & inhibitors | Vasodilation - physiology | Obesity, Morbid - metabolism | Organ Culture Techniques | Enzyme Inhibitors - pharmacology | Rats | Rats, Sprague-Dawley | Up-Regulation - drug effects | Animals | Endothelium, Vascular - metabolism | Arginine - pharmacology | Aged | Vasodilation - drug effects | Adipose Tissue - drug effects | Arginine - metabolism | Insulin resistance | Superoxide | Arginine | Nitric oxide | Fructose | Endothelium | Obesity | Rodents | Index Medicus | Adipose Tissue and Obesity | Research Paper | Endocrine and Metabolic Conditons, Disorders and Treatments | Cardiovascular | Vasculature
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10. Full Text Engraftment and Migration of Human Bone Marrow Stromal Cells Implanted in the Brains of Albino Rats--Similarities to Astrocyte Grafts
by S. Ausim Azizi and David Stokes and Brian J. Augelli and Carla DiGirolamo and Darwin J. Prockop
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 3/1998, Volume 95, Issue 7, pp. 3908 - 3913
Neurotransplantation has been used to explore the development of the central nervous system and for repair of diseased tissue in conditions such as Parkinson's... 
Brain | Astrocytes | Neurons | Stromal cells | Chondrocytes | Collagens | Stem cells | Antibodies | Bone marrow | Adipocytes | Neurotransplantation | Parkinson's disease | SURVIVAL | stem cells | ADULT-MOUSE BRAIN | STEM-CELLS | MULTIDISCIPLINARY SCIENCES | neurotransplantation | FIBROBLASTS | TRANSPLANTATION | FETAL MESENCEPHALIC TISSUE | MICE | PRECURSOR CELLS | PARKINSONS-DISEASE | Stromal Cells - transplantation | Stromal Cells - pathology | Humans | Middle Aged | Astrocytes - pathology | Bone Marrow Cells - pathology | Rats | Graft Survival | Male | Transplantation, Heterologous | Parkinson Disease - surgery | Animals | Brain - pathology | Adult | Brain - surgery | Female | Astrocytes - transplantation | Cell Movement | Transplants & implants | Rodents | Cells | Index Medicus | Biological Sciences | Parkinson’s disease
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11. Full Text Chronic administration of docosahexaenoic acid ameliorates the impairment of spatial cognition learning ability in amyloid β-infused rats
by Hashimoto, Michio and Tanabe, Yoko and Fujii, Yoshimi and Kikuta, Toshihiko and Shibata, Hitoshi and Shido, Osamu
Journal of Nutrition, ISSN 0022-3166, 03/2005, Volume 135, Issue 3, pp. 549 - 555
We investigated whether administration of docosahexaenoic acid (DHA), a major (n-3) fatty acid of the brain, ameliorates the impairment of learning ability in... 
Spatial working memory | Docosahexaenoic acid | Alzheimer's disease | Antioxidative defense | Therapeutic agent | VITAMIN-E | ALZHEIMERS-DISEASE | antioxidative defense | BRAIN PHOSPHOLIPIDS | PLASMA-MEMBRANE | HIPPOCAMPUS | SUPPLEMENTATION | therapeutic agent | NUTRITION & DIETETICS | docosahexaenoic acid | GENE-EXPRESSION | POLYUNSATURATED FATTY-ACIDS | IMPROVES | AGED RATS | spatial working memory | Docosahexaenoic Acids - therapeutic use | Reactive Oxygen Species | Rats, Wistar | Amyloid beta-Peptides - toxicity | Learning - drug effects | Alzheimer Disease - drug therapy | Rats | Cognition - drug effects | Docosahexaenoic Acids - pharmacology | Animals | Space Perception - drug effects | Alzheimer Disease - psychology | Disease Models, Animal | Index Medicus
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