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1998, Current topics in microbiology and immunology, ISBN 9783540633921, Volume 226., xiii, 198
Book
Nature, ISSN 0028-0836, 05/2011, Volume 473, Issue 7348, pp. 523 - 527
The acquired immunodeficiency syndrome (AIDS)-causing lentiviruses human immunodeficiency virus (HIV) and simian immunodeficiency virus (SIV) effectively evade... 
CHALLENGE | MACAQUE MODEL | REPLICATION | PROTECTION | RHESUS-MONKEYS | PRIMARY HIV-1 INFECTION | IMMUNE-RESPONSES | MULTIDISCIPLINARY SCIENCES | ACTIVE ANTIRETROVIRAL THERAPY | AIDS | IMMUNODEFICIENCY VIRUS SIVMAC239 | Immunity, Mucosal - immunology | Vaccines, DNA - genetics | Macaca mulatta - blood | AIDS Vaccines - immunology | Macaca mulatta - immunology | Vaccines, DNA - immunology | Simian Immunodeficiency Virus - growth & development | DNA, Viral - analysis | Male | Viral Load | CD4-Positive T-Lymphocytes - immunology | Simian Immunodeficiency Virus - isolation & purification | Macaca mulatta - virology | Simian Acquired Immunodeficiency Syndrome - virology | Time Factors | Immunologic Memory - immunology | Simian Immunodeficiency Virus - immunology | Cytomegalovirus - genetics | Simian Immunodeficiency Virus - pathogenicity | RNA, Viral - analysis | Simian Acquired Immunodeficiency Syndrome - blood | Genetic Vectors - genetics | Simian Acquired Immunodeficiency Syndrome - prevention & control | SAIDS Vaccines - genetics | Animals | SAIDS Vaccines - immunology | Simian Acquired Immunodeficiency Syndrome - immunology | Virus Replication | T-Lymphocytes - immunology | CD8-Positive T-Lymphocytes - immunology | Plasma | Immunization | Acquired immune deficiency syndrome--AIDS | Pathogenesis | Human immunodeficiency virus--HIV | Deoxyribonucleic acid--DNA | Index Medicus
Journal Article
Vaccine, ISSN 0264-410X, 2011, Volume 29, Issue 46, pp. 8417 - 8428
Highlights ► A phase I/II HIV vaccine trial has been conducted in Tanzania employing priming with HIV-1 DNA and boosting HIV-1 MVA. ► It has demonstrated... 
Allergy and Immunology | MVA boost | DNA prime | HIV vaccine | MEDICINE, RESEARCH & EXPERIMENTAL | VACCINIA VIRUS ANKARA | PHASE-1 SAFETY | IMMUNOGENICITY EVALUATION | CLADE-C | IMMUNOLOGY | DAR-ES-SALAAM | T-CELL RESPONSES | DOUBLE-BLIND | SMALLPOX VACCINATION | CANDIDATE VACCINE | MONOCLONAL-ANTIBODIES | Vaccines, DNA - genetics | Cell Proliferation | Humans | Viral Vaccines - genetics | AIDS Vaccines - immunology | Vaccines, DNA - immunology | Male | Neutralization Tests | Vaccines, Synthetic - immunology | Human Experimentation | Vaccines, DNA - administration & dosage | Vaccinia virus - genetics | Drug Carriers | Young Adult | Acquired Immunodeficiency Syndrome - immunology | Vaccination - methods | Leukocytes, Mononuclear - immunology | Adult | Female | Acquired Immunodeficiency Syndrome - virology | Placebos - administration & dosage | Injections, Intradermal | Interferon-gamma - secretion | Vaccines, Synthetic - genetics | Tanzania | Acquired Immunodeficiency Syndrome - prevention & control | Viral Proteins - genetics | Immunization, Secondary - methods | Enzyme-Linked Immunospot Assay | HIV-1 - genetics | Viral Vaccines - administration & dosage | HIV-1 - immunology | Plasmids | Adolescent | AIDS Vaccines - genetics | Vaccines, Synthetic - administration & dosage | AIDS Vaccines - administration & dosage | Genetic Vectors | Viral Vaccines - immunology | Interferon-gamma - biosynthesis | Viral antibodies | AIDS vaccines | Immune response | DNA | Vaccination | Antibodies | Universities and colleges | HIV (Viruses) | Biometry | Vaccines | Acquired immune deficiency syndrome--AIDS | Human immunodeficiency virus--HIV | Index Medicus | Immunization | CD8 antigen | Immune response (cell-mediated) | DNA vaccines | Lymphocytes T | Corticotropin-releasing hormone | CD4 antigen | glycoprotein gp160 | Gag protein | Immunogenicity | Interleukin 2 | Lymphocytes | Peripheral blood mononuclear cells | Serological tests | Enzyme-linked immunosorbent assay
Journal Article
PLoS One, ISSN 1932-6203, 2013, Volume 8, Issue 2, pp. e55571 - e55571
BACKGROUND: Gene-based vaccination using prime/boost regimens protects animals and humans against malaria, inducing cell-mediated responses that in animal... 
APICAL MEMBRANE ANTIGEN-1 | SPOROZOITE INOCULATION | VIRUS ANKARA | IMMUNIZATION | NEUTRALIZING ANTIBODIES | MULTIDISCIPLINARY SCIENCES | CIRCUMSPOROZOITE PROTEIN | DOUBLE-BLIND | NAIVE ADULTS | CYTOTOXIC T-LYMPHOCYTES | PHASE 2A TRIAL | Vaccines, DNA - genetics | Malaria, Falciparum - prevention & control | Antigens, Protozoan - immunology | Humans | Middle Aged | Vaccines, DNA - immunology | Male | Plasmodium falciparum - immunology | Protozoan Proteins - genetics | Young Adult | Malaria Vaccines - adverse effects | Plasmodium falciparum - genetics | Malaria Vaccines - immunology | Adult | Female | Antigens, Protozoan - genetics | Malaria Vaccines - therapeutic use | Membrane Proteins - genetics | Adenoviruses, Human - immunology | Membrane Proteins - immunology | Vaccines, DNA - therapeutic use | Malaria, Falciparum - parasitology | Interferon-gamma - immunology | Vaccines, DNA - adverse effects | Adolescent | Malaria, Falciparum - immunology | Adenoviruses, Human - genetics | CD8-Positive T-Lymphocytes - immunology | Immunity, Cellular | Protozoan Proteins - immunology | Malaria Vaccines - genetics | Antigens | Wildlife conservation | Malaria | Liver | Vaccination | Malaria vaccine | Vaccines | T cells | Plasmodium falciparum | Advertising executives | Mosquitoes | Control | Analysis | Adenoviruses | DNA | Bites and stings | Genetic aspects | Health aspects | Enzyme-linked immunosorbent assay | Flow cytometry | Animal models | Goats | CD8 antigen | Antibodies | Leukocytes (mononuclear) | Lymphocytes T | Parasites | Aquatic insects | Immunity | Immunity (cell-mediated) | Replicating | Acquired immune deficiency syndrome--AIDS | Sporozoites | Peripheral blood mononuclear cells | Deoxyribonucleic acid--DNA | Circumsporozoite protein | Expression vectors | Vector-borne diseases | Medical research | Immunization | Statistical analysis | Diarrhea | Vectors | Membrane proteins | Cytometry | Plasmids | γ-Interferon | Interferon | Index Medicus | Acquired immune deficiency syndrome | Deoxyribonucleic acid | AIDS
Journal Article
Nature, ISSN 0028-0836, 01/2012, Volume 481, Issue 7379, pp. 81 - 86
Journal Article
Journal of Infectious Diseases, ISSN 0022-1899, 07/2014, Volume 210, Issue 1, pp. 99 - 110
Journal Article
Nature, ISSN 0028-0836, 12/2016, Volume 540, Issue 7632, pp. 284 - 287
The development of immunologic interventions that can target the viral reservoir in HIV-1-infected individuals is a major goal of HIV-1 research(1,2). However,... 
INDIVIDUALS | VIREMIA | PERSISTENCE | MULTIDISCIPLINARY SCIENCES | ACTIVE ANTIRETROVIRAL THERAPY | MACAQUES | LATENT RESERVOIR | T-CELLS | CHALLENGES | VIRAL RESERVOIR | HIV-1 REMISSION | AIDS Vaccines - immunology | Simian Immunodeficiency Virus - growth & development | DNA, Viral - analysis | Male | RNA, Viral - blood | Macaca mulatta | Vaccinia virus - genetics | Simian Immunodeficiency Virus - isolation & purification | HIV Infections - immunology | Simian Acquired Immunodeficiency Syndrome - virology | Simian Immunodeficiency Virus - genetics | Time Factors | Toll-Like Receptor 7 - immunology | Adenoviridae - genetics | Female | Simian Acquired Immunodeficiency Syndrome - therapy | Simian Immunodeficiency Virus - immunology | Toll-Like Receptor 7 - genetics | RNA, Viral - analysis | Immunity, Innate | Viral Load - immunology | Genetic Vectors - genetics | DNA, Viral - blood | SAIDS Vaccines - genetics | Animals | SAIDS Vaccines - immunology | Simian Acquired Immunodeficiency Syndrome - immunology | Anti-Retroviral Agents - administration & dosage | HIV Infections - therapy | AIDS Vaccines - genetics | Immunity, Cellular | Prevention | TLR7 | Dosage and administration | Viral vaccines | Health aspects | HIV infection | Immunization | Adenoviruses | Human immunodeficiency virus--HIV | Viruses | Vaccines | Monkeys & apes | Viral infections | Index Medicus
Journal Article
PLoS ONE, ISSN 1932-6203, 11/2018, Volume 13, Issue 11, pp. e0206838 - e0206838
Background We evaluated the safety and immunogenicity of (i) an intradermal HIV-DNA regimen given with/without intradermal electroporation (EP) as prime and... 
HUMORAL IMMUNE-RESPONSES | ELECTROPORATION | DNA VACCINE | SAFETY | MULTIDISCIPLINARY SCIENCES | BROAD | TYPE-1 | HIV Antibodies - blood | Immunogenicity, Vaccine | HIV Infections - prevention & control | Vaccines, DNA - genetics | env Gene Products, Human Immunodeficiency Virus - immunology | Humans | Viral Vaccines - genetics | AIDS Vaccines - immunology | Vaccines, DNA - immunology | Glucosides - immunology | Male | Administration, Cutaneous | Healthy Volunteers | Viral Vaccines - adverse effects | Vaccines, DNA - administration & dosage | AIDS Vaccines - adverse effects | Vaccinia virus - immunology | Young Adult | Antibodies, Neutralizing - immunology | env Gene Products, Human Immunodeficiency Virus - genetics | Lipid A - immunology | Mozambique | Vaccination - methods | HIV Antibodies - immunology | Adult | Female | Tanzania | Electroporation | Immunization, Secondary - methods | Viral Vaccines - administration & dosage | HIV-1 - immunology | Vaccines, DNA - adverse effects | AIDS Vaccines - genetics | AIDS Vaccines - administration & dosage | Viral Vaccines - immunology | Antibodies, Neutralizing - blood | Antigens | AIDS vaccines | Vaccination | DNA | Genetic research | Clinical trials | Lipids | Product development | HIV (Viruses) | Laboratories | Viruses | Infections | DNA vaccines | Vaccines | Lipid A | Proteins | Randomization | Immunology | Gag protein | Acquired immune deficiency syndrome--AIDS | Audio frequencies | Safety engineering | Human immunodeficiency virus--HIV | Safety | Public health | Deoxyribonucleic acid--DNA | Enzyme-linked immunosorbent assay | Medical research | Immunization | Immunoglobulins | Internal medicine | Envelope protein | Priming | Medicine | Glycoprotein gp160 | Hospitals | Infectious diseases | Immunogenicity | γ-Interferon | Adults | Glycoprotein gp120 | Index Medicus | Acquired immune deficiency syndrome | Deoxyribonucleic acid | AIDS | HIV | Human immunodeficiency virus
Journal Article