X
Search Filters
Format Format
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
akr1c3 (128) 128
humans (105) 105
index medicus (104) 104
aldo-keto reductase family 1 member c3 (59) 59
male (47) 47
3-hydroxysteroid dehydrogenases - metabolism (42) 42
hydroxyprostaglandin dehydrogenases - metabolism (42) 42
prostate cancer (41) 41
biochemistry & molecular biology (39) 39
cancer (38) 38
oncology (38) 38
endocrinology & metabolism (33) 33
expression (33) 33
cell line, tumor (32) 32
testosterone (31) 31
female (30) 30
androgen receptor (29) 29
pharmacology & pharmacy (29) 29
enzymes (28) 28
animals (26) 26
hydroxyprostaglandin dehydrogenases - antagonists & inhibitors (25) 25
3-hydroxysteroid dehydrogenases - antagonists & inhibitors (24) 24
3-hydroxysteroid dehydrogenases - genetics (24) 24
5 17-beta-hydroxysteroid-dehydrogenase akr1c3 (24) 24
article (24) 24
prostate-cancer (24) 24
chemistry, medicinal (23) 23
hydroxyprostaglandin dehydrogenases - genetics (23) 23
physiological aspects (21) 21
metabolism (20) 20
middle aged (20) 20
aldo-keto reductase (18) 18
analysis (18) 18
aldo-keto reductases (17) 17
androgens (17) 17
enzyme inhibitors - pharmacology (17) 17
resistance (17) 17
aged (16) 16
immunohistochemistry (16) 16
toxicology (16) 16
enzyme inhibitors - chemistry (15) 15
inhibitors (15) 15
nonsteroidal antiinflammatory drugs (15) 15
adult (14) 14
cell biology (14) 14
gene expression (14) 14
keto reductase superfamily (14) 14
mice (14) 14
selective inhibitors (14) 14
urologic and male genital diseases (14) 14
3-alpha-hydroxysteroid dehydrogenase (13) 13
dose-response relationship, drug (13) 13
structure-activity relationship (13) 13
17-beta-hydroxysteroid-dehydrogenase akr1c3 (12) 12
androgen (12) 12
breast-cancer (12) 12
castration-resistant prostate cancer (12) 12
cell survival - drug effects (12) 12
cells (12) 12
inhibition (12) 12
keto reductase akr1c3 (12) 12
molecular structure (12) 12
prostatic neoplasms - metabolism (12) 12
risk (12) 12
target (12) 12
abiraterone acetate (11) 11
indomethacin (11) 11
potent (11) 11
17-beta-hydroxysteroid-dehydrogenase (10) 10
aldo-keto reductase 1c3 (10) 10
care and treatment (10) 10
dihydrotestosterone (10) 10
health aspects (10) 10
increased expression (10) 10
oxidative stress (10) 10
prostate (10) 10
prostatic neoplasms - pathology (10) 10
receptor (10) 10
receptors, androgen - metabolism (10) 10
research (10) 10
resistant prostate-cancer (10) 10
steroidogenesis (10) 10
steroids (10) 10
activation (9) 9
carcinoma (9) 9
cell proliferation - drug effects (9) 9
crystal-structures (9) 9
enzyme inhibitors - chemical synthesis (9) 9
f synthase (9) 9
increased survival (9) 9
metastasis (9) 9
prostaglandin-f synthase (9) 9
prostaglandins (9) 9
prostatic neoplasms, castration-resistant - metabolism (9) 9
reveals roles (9) 9
tissue distribution (9) 9
abiraterone (8) 8
akr1c3 inhibitors (8) 8
aldo-keto reductase family 1 member c3 - metabolism (8) 8
androgens - biosynthesis (8) 8
more...
Language Language
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Journal of Biochemistry (Tokyo), ISSN 0021-924X, 11/1998, Volume 124, Issue 5, pp. 940 - 946
Human 3 alpha -hydroxysteroid dehydrogenase exists in four isoforms, which belong to the aldo-keto reductase (AKR) superfamily and are named AKR1C1-AKR1C4. The... 
AKR1C4 gene | AKR1C1 gene | prostaglandin D2 | androstanes | AKR1C3 gene | AKR1C2 gene
Journal Article
Journal of Steroid Biochemistry and Molecular Biology, ISSN 0960-0760, 11/1999, Volume 71, Issue 1-2, pp. 29 - 39
Journal Article
Journal Article
Mut.Res.-Genetic Toxicology and Environmental Mutagenesis, ISSN 1383-5718, 2005, Volume 582, Issue 1, pp. 53 - 60
Journal Article
Journal Article
Journal Article
Gene, ISSN 0378-1119, 2006, Volume 380, Issue 2, pp. 137 - 143
Journal Article
Endocrine-Related Cancer, ISSN 1351-0088, 03/2006, Volume 13, Issue 1, pp. 169 - 180
Type 2 3α-hydroxysteroid dehydrogenase (3α-HSD) is a multi-functional enzyme that possesses 3α-, 17β- and 20α-HSD, as well as prostaglandin (PG) F synthase... 
KETO REDUCTASE AKR1C3 | HYDROXYSTEROID DEHYDROGENASE | LOCALIZATION | LNCAP CELL-PROLIFERATION | WALLABY POUCH YOUNG | 3-BETA-HYDROXYSTEROID DEHYDROGENASE | ONCOLOGY | PPAR-GAMMA LIGANDS | GROWTH | ENDOCRINOLOGY & METABOLISM | DIFFERENTIATION | CANCER
Journal Article
Molecular and Cellular Endocrinology, ISSN 0303-7207, 2006, Volume 248, Issue 1, pp. 233 - 235
17β-Hydroxysteroid dehydrogenase type 5 (AKR1C3) that is involved in the pre-receptor regulation of androgen and estrogen action in the human is an emerging... 
AKR1C3 | Inhibitors | Aldo–keto reductase | Cinnamic acid | Cancer | Aldo-keto reductase
Journal Article
Molecular and Cellular Endocrinology, ISSN 0303-7207, 2006, Volume 253, Issue 1, pp. 44 - 55
Paracrine interactions between adipose fibroblasts and malignant epithelial cells are essential for structural and hormonal support of breast tumors. Factors... 
Epithelial–stromal interaction | AKR1C3 | Breast adipose fibroblast | Breast cancer | Aromatase | Estrogen | Epithelial-stromal interaction | KETO REDUCTASE AKR1C3 | estrogen | breast adipose fibroblast | REGULATES EXPRESSION | aromatase | ADIPOSE STROMAL CELLS | breast cancer | ALTERNATIVE PROMOTERS | RAT MAMMARY-GLAND | CELL BIOLOGY | EPITHELIAL-CELLS | epithelial-stromal interaction | ENDOCRINOLOGY & METABOLISM | ESTROGEN BIOSYNTHESIS | 5 17-BETA-HYDROXYSTEROID-DEHYDROGENASE | POLYMERASE CHAIN-REACTION | AROMATASE EXPRESSION | Immunohistochemistry | Humans | Middle Aged | Adipose Tissue - cytology | Aromatase - metabolism | Culture Media, Conditioned - pharmacology | Gene Expression Profiling | Hydroxyprostaglandin Dehydrogenases - metabolism | Breast Neoplasms - metabolism | RNA, Messenger - biosynthesis | Aromatase - genetics | Polymerase Chain Reaction | 3-Hydroxysteroid Dehydrogenases - metabolism | Adult | Female | Fibroblasts - metabolism | Estradiol - metabolism | Cells, Cultured | Paracrine Communication - genetics | Hydroxyprostaglandin Dehydrogenases - genetics | Aldo-Keto Reductase Family 1 Member C3 | Fibroblasts - drug effects | Adolescent | Cell Line, Tumor | 3-Hydroxysteroid Dehydrogenases - genetics | Enzymes | Testosterone | Messenger RNA | Analysis | Genetic research | Phenols | Cytoskeletal proteins | Gene expression | Medicine, Preventive | Estradiol | Preventive health services
Journal Article
MOLECULAR AND CELLULAR ENDOCRINOLOGY, ISSN 0303-7207, 03/2006, Volume 248, Issue 1-2, pp. 233 - 235
17 beta-Hydroxysteroid dehydrogenase type 5 (AKR1C3) that is involved in the pre-receptor regulation of androgen and estrogen action in the human is an... 
inhibitors | ISOFORMS | 17-BETA-HYDROXYSTEROID-DEHYDROGENASE | KETO REDUCTASE SUPERFAMILY | DRUGS | ENDOCRINOLOGY & METABOLISM | AKR1C3 | cinnamic acid | cancer | aldo-keto reductase | 3-ALPHA-HYDROXYSTEROID DEHYDROGENASE | CELL BIOLOGY
Journal Article
Experimental Dermatology, ISSN 0906-6705, 09/2007, Volume 16, Issue 9, pp. 762 - 769
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 03/2007, Volume 282, Issue 11, pp. 8368 - 8379
Human type 5 17 beta-hydroxysteroid dehydrogenase plays a crucial role in local androgen formation in prostate tissue. Several chemicals were synthesized and... 
LHRH AGONIST | 3-BETA-HYDROXYSTEROID DEHYDROGENASE | NONSTEROIDAL ANTIINFLAMMATORY DRUGS | KETO REDUCTASE SUPERFAMILY | BIOCHEMISTRY & MOLECULAR BIOLOGY | PROSTATE-CANCER | HUMAN ESTROGENIC 17-BETA-HYDROXYSTEROID-DEHYDROGENASE | IN-SITU HYBRIDIZATION | ANDROGEN | AKR1C3 | CRYSTAL-STRUCTURES
Journal Article