X
Search Filters
Format Format
Format Format
X
Sort by Item Count (A-Z)
Filter by Count
Journal Article (75476) 75476
Dissertation (603) 603
Book Chapter (377) 377
Book / eBook (98) 98
Publication (54) 54
Magazine Article (49) 49
Conference Proceeding (41) 41
Government Document (38) 38
Newspaper Article (34) 34
Art (24) 24
Paper (12) 12
Web Resource (6) 6
Newsletter (1) 1
Streaming Video (1) 1
more...
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
humans (35642) 35642
animals (33013) 33013
proto-oncogene proteins c-akt - metabolism (29260) 29260
phosphorylation (21641) 21641
apoptosis (21346) 21346
akt (21229) 21229
signal transduction (20208) 20208
mice (19041) 19041
akt protein (16957) 16957
oncology (14952) 14952
activation (14770) 14770
male (14553) 14553
expression (14426) 14426
cell biology (13868) 13868
cell line, tumor (13526) 13526
phosphatidylinositol 3-kinases - metabolism (13443) 13443
biochemistry & molecular biology (12267) 12267
female (12010) 12010
cancer (11994) 11994
proteins (11828) 11828
signal transduction - drug effects (11822) 11822
kinases (11428) 11428
rats (9573) 9573
cell proliferation (8442) 8442
apoptosis - drug effects (8370) 8370
gene expression (7592) 7592
1-phosphatidylinositol 3-kinase (7466) 7466
cells, cultured (7433) 7433
inhibition (7170) 7170
growth (6530) 6530
proto-oncogene proteins c-akt - genetics (6254) 6254
pathway (6182) 6182
proliferation (6120) 6120
cell proliferation - drug effects (6063) 6063
proto-oncogene proteins c-akt (6062) 6062
research (5741) 5741
cell line (5557) 5557
analysis (5539) 5539
pharmacology & pharmacy (5530) 5530
cells (5394) 5394
tumors (5210) 5210
oxidative stress (5179) 5179
survival (5177) 5177
phosphorylation - drug effects (5172) 5172
metastasis (5064) 5064
insulin (4989) 4989
cell cycle (4893) 4893
medicine, research & experimental (4841) 4841
proto-oncogene proteins - metabolism (4782) 4782
blotting, western (4757) 4757
signal transduction - physiology (4672) 4672
multidisciplinary sciences (4555) 4555
signaling (4483) 4483
research article (4481) 4481
inflammation (4440) 4440
pi3k (4423) 4423
cell growth (4403) 4403
rodents (4344) 4344
medicine (4241) 4241
health aspects (4177) 4177
mice, inbred c57bl (4068) 4068
cell survival - drug effects (4025) 4025
tor serine-threonine kinases - metabolism (3971) 3971
physiology (3951) 3951
neurosciences (3919) 3919
antineoplastic agents - pharmacology (3827) 3827
cell survival (3803) 3803
mutation (3795) 3795
in-vitro (3783) 3783
breast cancer (3775) 3775
rats, sprague-dawley (3728) 3728
physiological aspects (3684) 3684
genetic aspects (3659) 3659
angiogenesis (3610) 3610
kinase (3601) 3601
proto-oncogene proteins c-akt - antagonists & inhibitors (3595) 3595
middle aged (3573) 3573
biology (3555) 3555
extracellular signal-regulated kinase (3547) 3547
phosphatidylinositol 3-kinases - antagonists & inhibitors (3522) 3522
phosphatidylinositol 3-kinase (3485) 3485
protein-serine-threonine kinases - metabolism (3471) 3471
disease models, animal (3436) 3436
down-regulation (3435) 3435
nf-kappa-b (3396) 3396
mtor (3393) 3393
protein (3380) 3380
metabolism (3378) 3378
enzyme activation (3363) 3363
gene-expression (3362) 3362
up-regulation (3336) 3336
science (3315) 3315
enzyme inhibitors - pharmacology (3235) 3235
endocrinology & metabolism (3192) 3192
autophagy (3186) 3186
gene expression regulation, neoplastic (3164) 3164
signaling pathway (3159) 3159
transfection (3153) 3153
immunohistochemistry (3140) 3140
dose-response relationship, drug (3123) 3123
more...
Library Location Library Location
Library Location Library Location
X
Sort by Item Count (A-Z)
Filter by Count
Robarts - Stacks (48) 48
UTL at Downsview - May be requested (15) 15
Collection Dvlpm't (Acquisitions) - Vendor file (14) 14
UofT at Mississauga - Stacks (7) 7
UofT at Scarborough - Stacks (6) 6
Robarts - Protected Material (4) 4
Robarts - Petro Jacyk (3) 3
Victoria University E.J. Pratt - Stacks (3) 3
Art - Library use only (2) 2
Collection Dvlpm't (Acquisitions) - Closed Orders (2) 2
Online Resources - Online (2) 2
St. Michael's College (John M. Kelly) - 3rd Floor (2) 2
Trinity College (John W Graham) - Stacks (2) 2
Architecture Landscape (Shore + Moffat) - Stacks (1) 1
Collection Dvlpm't (Acquisitions) - Cancelled Order (1) 1
Engineering & Comp. Sci. - Stacks (1) 1
Innis College - Stacks (1) 1
Institute for Christian Studies - Stacks (1) 1
Knox College (Caven) - Stacks (1) 1
Law (Bora Laskin) - Reserve desk (1) 1
Law (Bora Laskin) - Stacks (1) 1
Map & Data - Map Collection (1) 1
New College (Ivey) - Stacks (1) 1
Robarts - In process for Downsview (1) 1
Robarts - Library use only (1) 1
Royal Ontario Museum - Stacks (1) 1
Stacks (1) 1
more...
Language Language
Language Language
X
Sort by Item Count (A-Z)
Filter by Count
English (73938) 73938
Chinese (2334) 2334
Japanese (421) 421
German (265) 265
Swedish (205) 205
French (139) 139
Korean (118) 118
Portuguese (80) 80
Spanish (52) 52
Polish (48) 48
Russian (38) 38
Czech (31) 31
Croatian (19) 19
Italian (11) 11
Belarusian (9) 9
Norwegian (9) 9
Turkish (8) 8
Dutch (7) 7
Hungarian (7) 7
Danish (1) 1
Latin (1) 1
Romanian (1) 1
Serbian (1) 1
Slovak (1) 1
Welsh (1) 1
more...
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


British journal of clinical pharmacology, ISSN 0306-5251, 2016, Volume 82, Issue 4, pp. 943 - 956
Journal Article
World journal of gastroenterology : WJG, ISSN 1007-9327, 2015, Volume 21, Issue 43, pp. 12261 - 12273
Frequent activation of phosphatidylinositol-3 kinases(PI3K)/Akt/m TOR signaling pathway in gastric cancer(GC) is gaining immense popularity with identification... 
Epidemiology;Gastric | pathwa | cancer;PI3K/Akt | TOR | Targeted therapy | Epidemiology | Gastric cancer | Predictive biomarkers | PI3K/AKT/ MTOR pathway | CANCER-CELLS | MAMMALIAN TARGET | ADVANCED SOLID TUMORS | CELL-CYCLE PROGRESSION | ANTITUMOR-ACTIVITY | PI3K/Akt/mTOR pathway | AKT/PROTEIN KINASE-B | PHOSPHATIDYLINOSITOL 3-KINASE INHIBITOR | PHOSPHOINOSITIDE 3-KINASES | GASTROENTEROLOGY & HEPATOLOGY | NF-KAPPA-B | PHASE-I | TOR Serine-Threonine Kinases - metabolism | Phosphatidylinositol 3-Kinase - antagonists & inhibitors | Humans | Drug Discovery - methods | Stomach Neoplasms - pathology | Antineoplastic Agents - therapeutic use | Molecular Targeted Therapy | Proto-Oncogene Proteins c-akt - genetics | TOR Serine-Threonine Kinases - antagonists & inhibitors | Carcinoma - enzymology | Biomarkers, Tumor - metabolism | Biomarkers, Tumor - antagonists & inhibitors | Carcinoma - pathology | Proto-Oncogene Proteins c-akt - metabolism | Phosphatidylinositol 3-Kinase - metabolism | Precision Medicine | Carcinoma - drug therapy | Stomach Neoplasms - enzymology | Stomach Neoplasms - genetics | Treatment Outcome | Stomach Neoplasms - drug therapy | Animals | Phosphatidylinositol 3-Kinase - genetics | Signal Transduction - drug effects | Protein Kinase Inhibitors - therapeutic use | Carcinoma - genetics | Biomarkers, Tumor - genetics | Proto-Oncogene Proteins c-akt - antagonists & inhibitors | PI3K | mTOR pathway | Akt | Topic Highlight
Journal Article
Biochemical journal, ISSN 1470-8728, 2007, Volume 407, Issue 2, pp. 231 - 241
AS160 (Akt substrate of 160 kDa) mediates insulin-stimulated GLUT4 (glucose transporter 4) translocation, but is widely expressed in insulin-insensitive... 
14-3-3 | Akt/protein kinase B (PKB) | GTPase-activating protein (GAP) | p90 ribosomal S6 kinase (RSK) | Akt substrate of 160 kDa (AS160) | Serum- and glucocorticoid-induced protein kinase (SGK) | MAMMALIAN TARGET | BIOCHEMISTRY & MOLECULAR BIOLOGY | Akt substrate of 160kDa (AS160) | AKT SUBSTRATE | CELL-GROWTH | GTPASE-ACTIVATING PROTEIN | SKELETAL-MUSCLE | INSULIN-STIMULATED PHOSPHORYLATION | GLUT4 TRANSLOCATION | S6 KINASE | PROTEOMIC ANALYSIS | RAB-GAP | serum- and glucocorticoid-induced protein kinase (SGK) | Cell Line | Insulin-Like Growth Factor I - pharmacology | Phosphorylation | Humans | GTPase-Activating Proteins - metabolism | Insulin | Amino Acids | Aminoimidazole Carboxamide - pharmacology | Hypoglycemic Agents - pharmacology | 14-3-3 Proteins - metabolism | Ribonucleotides - pharmacology | Aminoimidazole Carboxamide - analogs & derivatives | Protein Binding | Epidermal Growth Factor - pharmacology | Binding Sites | ACC, acetyl-CoA carboxylase | AGC kinase, protein kinase A | AICAR, 5-amino-4-imidazolecarboxamide1-β-D-ribofuranoside | PI3K, phosphoinositide 3-kinase | EGF, epidermal growth factor | TOS motif, mTOR signalling motif | PAS, phospho-Akt substrate | pSer, phosphorylated serine | TSC, tuberous sclerosis complex | AS160, Akt substrate of 160 kDa | PKB, protein kinase B (also known as Akt) | AMPK, AMP-activated protein kinase | RSK, p90 ribosomal S6 kinase | DSP, dithiobis(succinimidyl propionate) | protein kinase C-family | ERK, extracellular-signal-regulated kinase | PDK1, phosphoinositide-dependent kinase 1 | protein kinase B (PKB) | IGF-1, insulin-like growth factor-1 | Akt substrate of 160 kDa (AS160) | GLUT4, glucose transporter 4 | protein kinase G | mTOR, mammalian target of rapamycin | TORC1, mTOR–raptor (regulatory associated protien of mTOR) complex | 4E-BP1, eukaryotic initiation factor 4E-binding protein 1 | GST, glutathione S-transferase | PKC, protein kinase C | PP2A, protein phosphatase 2A | Akt | SGK, serum- and glucocorticoid-induced protein kinase | HA, haemagglutinin | GSV, GLUT4 storage vesicle | p70S6K, p70 S6 kinase | PTB, phosphotyrosine binding domain | pThr, phosphorylated threonine | GAP, GTPase-activating protein | HEK-293, human embryonic kidney-293 | IRAP, insulin-responsive aminopeptidase | Rheb, Ras enriched in brain | MAPK, mitogen-activated protein kinase
Journal Article
PLoS biology, ISSN 1545-7885, 2009, Volume 7, Issue 6, p. e1000121
Journal Article
Nature (London), ISSN 1476-4687, 2014, Volume 508, Issue 7497, pp. 541 - 545
Journal Article
Oncotarget, ISSN 1949-2553, 2014, Volume 5, Issue 14, pp. 5295 - 5303
ARID1A mutations are observed in various tumors, including ovarian clear cell (OCCC) and endometrioid carcinomas, endometrial, and breast carcinomas. They... 
BAF250a | Endometriosis associated ovarian carcinomas | Endometrial cancer | Perifosine | AKT-inhibitor | Buparlisib (BKM120) | Breast cancer | ARID1A | PI3K/AKT pathway | PIK3CA | SWI/SNF | MK-2206 | PI3K-inhibitor | AKT phosphorylation | Ovarian clear cell carcinomas | Apoptosis | RNA, Small Interfering - genetics | Phosphorylation | Apoptosis - drug effects | Heterocyclic Compounds, 3-Ring - pharmacology | Humans | Transcription Factors - deficiency | Phosphatidylinositol 3-Kinases - metabolism | Phosphorylcholine - analogs & derivatives | Phosphatidylinositol 3-Kinases - antagonists & inhibitors | Proto-Oncogene Proteins c-akt - genetics | Breast Neoplasms - metabolism | Gene Knockdown Techniques | Breast Neoplasms - therapy | Breast Neoplasms - enzymology | Transfection | MCF-7 Cells | Nuclear Proteins - biosynthesis | Nuclear Proteins - deficiency | Phosphorylcholine - pharmacology | Female | Nuclear Proteins - genetics | Proto-Oncogene Proteins c-akt - metabolism | Ribosomal Protein S6 Kinases, 70-kDa - metabolism | Signal Transduction | Morpholines - pharmacology | Nuclear Proteins - metabolism | Transcription Factors - biosynthesis | Transcription Factors - genetics | Transcription Factors - metabolism | Breast Neoplasms - pathology | Aminopyridines - pharmacology | Protein Kinase Inhibitors - pharmacology | Apoptosis - physiology | RNA, Small Interfering - administration & dosage | Proto-Oncogene Proteins c-akt - antagonists & inhibitors
Journal Article
Journal Article