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Nature Cell Biology, ISSN 1465-7392, 03/2007, Volume 9, Issue 3, pp. 316 - 323
Journal Article
Journal Article
Journal Article
Cell, ISSN 0092-8674, 2006, Volume 127, Issue 1, pp. 125 - 137
Mammalian target of rapamycin (mTOR) controls cell growth and proliferation via the raptor-mTOR (TORC1) and rictor-mTOR (TORC2) protein complexes. Recent... 
ACTIVATION | PROTEIN-KINASE-B | SIGNALING PATHWAY | TOR | BIOCHEMISTRY & MOLECULAR BIOLOGY | HYDROPHOBIC MOTIF PHOSPHORYLATION | TUBEROUS SCLEROSIS | CELL-GROWTH | FOXO TRANSCRIPTION FACTORS | SACCHAROMYCES-CEREVISIAE | BINDING-PROTEINS | CELL BIOLOGY | Protein Kinases - metabolism | Phosphorylation | Protein Kinases - genetics | Humans | Multiprotein Complexes | Substrate Specificity | Phosphoproteins - metabolism | Threonine - metabolism | Proto-Oncogene Proteins c-akt - genetics | Forkhead Transcription Factors - metabolism | Regulatory-Associated Protein of mTOR | Proto-Oncogene Proteins c-akt - metabolism | Fibroblasts - metabolism | Rapamycin-Insensitive Companion of mTOR Protein | Mice, Inbred C57BL | Cells, Cultured | Gene Silencing | Phosphoproteins - genetics | Transcription Factors - genetics | Forkhead Transcription Factors - genetics | Mice, Knockout | Proteins - genetics | Transcription Factors - metabolism | Carrier Proteins - genetics | Animals | Carrier Proteins - metabolism | Proteins - metabolism | Adaptor Proteins, Signal Transducing - genetics | Signal Transduction - physiology | Fibroblasts - cytology | Forkhead Box Protein O1 | Mice | TOR Serine-Threonine Kinases | Adaptor Proteins, Signal Transducing - metabolism | Forkhead Box Protein O3 | Rapamycin | Research | Physiological aspects | Mars (Planet)
Journal Article
Nature Cell Biology, ISSN 1465-7392, 05/2008, Volume 10, Issue 5, pp. 513 - 526
Journal Article
Bioorganic & Medicinal Chemistry Letters, ISSN 0960-894X, 2007, Volume 17, Issue 7, pp. 2068 - 2073
The progression of GSK3β substrate-mimetic inhibitors towards the development of a potent, small molecule substrate-mimetic inhibitor of Akt is reported.... 
Substrate-mimetic | Protein kinase B | Akt | Peptidomimetics | Cancer | CANCER-CELLS | substratemimetic | ACTIVATION | CHEMISTRY, MEDICINAL | PROTEIN-KINASE-B | PKB INHIBITORS | PHOSPHORYLATION | CHEMISTRY, ORGANIC | DISCOVERY | ONCOGENE | AMPLIFICATION | cancer | peptidomimetics | MOLECULAR-CLONING | DERIVATIVES | protein kinase B
Journal Article
European Journal of Immunology, ISSN 0014-2980, 06/2015, Volume 45, Issue 6, pp. 1621 - 1634
Journal Article