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PloS one, ISSN 1932-6203, 04/2017, Volume 12, Issue 4, p. e0173676
.... Chronic administration of the PPARa agonist FB substantially reduced the levels of multiple autophagy proteins in the liver... 
INSULIN SIGNALING TRANSDUCTION | GLUCOSE-HOMEOSTASIS | FIBROBLAST-GROWTH-FACTOR-21 | DEACETYLATION | METABOLISM | PATHWAY | STEATOSIS | MULTIDISCIPLINARY SCIENCES | RESISTANCE | RECEPTORS | FOXO1 | TOR Serine-Threonine Kinases - metabolism | Autophagy-Related Protein 7 - metabolism | Fibroblast Growth Factors - genetics | Autophagy-Related Protein 5 - genetics | fas Receptor - metabolism | Autophagy - drug effects | Fibroblast Growth Factors - metabolism | TOR Serine-Threonine Kinases - genetics | Liver - drug effects | fas Receptor - genetics | Autophagy - genetics | Proto-Oncogene Proteins c-akt - metabolism | Forkhead Box Protein O1 - metabolism | Signal Transduction | Liver - metabolism | PPAR alpha - genetics | Ubiquitin-Conjugating Enzymes - genetics | Stearoyl-CoA Desaturase - genetics | Mice, Knockout | Triglycerides - metabolism | Sequestosome-1 Protein - genetics | Ubiquitin-Conjugating Enzymes - metabolism | Cysteine Endopeptidases - genetics | Autophagy-Related Protein 5 - metabolism | Beclin-1 - genetics | Stearoyl-CoA Desaturase - metabolism | Mice | PPAR alpha - metabolism | Autophagy-Related Proteins - antagonists & inhibitors | Blood Glucose - metabolism | Autophagy-Related Proteins - metabolism | Forkhead Box Protein O1 - genetics | Autophagy-Related Protein 5 - antagonists & inhibitors | Microtubule-Associated Proteins - genetics | Microtubule-Associated Proteins - metabolism | Proto-Oncogene Proteins c-akt - genetics | Fenofibrate - pharmacology | Cysteine Endopeptidases - metabolism | Autophagy-Related Proteins - genetics | Sequestosome-1 Protein - metabolism | Sterol Regulatory Element Binding Protein 1 - metabolism | Autophagy-Related Protein 7 - antagonists & inhibitors | Mice, Inbred C57BL | Autophagy-Related Protein 7 - genetics | Gene Expression Regulation - drug effects | Animals | Sterol Regulatory Element Binding Protein 1 - genetics | PPAR alpha - agonists | Ubiquitin-Conjugating Enzymes - antagonists & inhibitors | Beclin-1 - metabolism | Transcription factors | Adipose tissue | Liver | Body weight | AKT protein | Biochemistry | Glucose | Assaying | Proteins | Signal transduction | Temperature effects | Fibroblasts | Physiology | Acetylation | Inhibition | Growth factors | Hepatotoxicity | Activation analysis | Methanol | Starvation | Ethanol | AMP | Metabolism | Insulin | Fatty acids | Studies | Acetaminophen | Food intake | Weight reduction | Animal welfare | Circulation | Drugs | Biotechnology | Drug abuse | Laboratories | Centrifugation | Glass | Homeostasis | Activation | Biology | Kinases | AMP-activated protein kinase | Autophagy | Nutrient status | Rodents | Nutrients | Oxidation | Heart diseases | Age | Epinephrine | AKT1 protein | Fasting | Chloroform | Diabetes mellitus | Cardiomyocytes | Acclimatization | Triglycerides | Pharmacology | Nitrogen | Calories | Medicine | Nuclear fuels | Protein kinase | Insulin resistance | Diabetes
Journal Article
The Plant cell, ISSN 1532-298X, 2017, Volume 29, Issue 2, pp. 409 - 422
Journal Article
PloS one, ISSN 1932-6203, 2007, Volume 2, Issue 10, p. e1058
Journal Article
Journal Article
PloS one, ISSN 1932-6203, 04/2016, Volume 11, Issue 4, p. e0153882
...) infection and hepatocellular carcinoma (HCC). An increasing number of studies show that protein-protein interactions (PPIs... 
PATHWAYS | APOPTOSIS | COMPLEX | REPLICATION | NS5A | LANDSCAPE | MULTIDISCIPLINARY SCIENCES | EXPRESSION | P53 | NS3 | Hepatitis C, Chronic - metabolism | Cell Proliferation | Signal Transduction | Humans | Hepacivirus - pathogenicity | Hepatitis C, Chronic - complications | Neoplasm Proteins - metabolism | Glycogen Synthase Kinase 3 beta - metabolism | Viral Proteins - metabolism | beta Catenin - metabolism | Hepacivirus - metabolism | Protein Interaction Maps | Liver Neoplasms - etiology | Algorithms | Carcinoma, Hepatocellular - pathology | Liver Neoplasms - metabolism | Cell Line, Tumor | Liver Neoplasms - pathology | Viral Nonstructural Proteins - metabolism | Carcinoma, Hepatocellular - etiology | Proto-Oncogene Proteins c-akt - metabolism | Carcinoma, Hepatocellular - metabolism | Cell Movement | Viral proteins | Physiological aspects | Development and progression | Genetic aspects | Research | Hepatoma | Hepatitis C virus | Protein-protein interactions | Cell proliferation | Wnt protein | Aviation | Pathogenesis | p53 Protein | Viruses | Hepatocellular carcinoma | AKT protein | Infections | Kinases | Epidemiology | Metastases | Proteins | Hepatitis | Liver cancer | β-catenin | Network analysis | HCc protein | Cell cycle | AKT1 protein | Liver diseases | Aerospace medicine | Random walk | MAP kinase | Gene expression | Disease control | Virology | Tumor necrosis factor | Plasmids | Hepatitis C | Protein interaction | Apoptosis
Journal Article
Scientific reports, ISSN 2045-2322, 2017, Volume 7, Issue 1, p. 42700
The survival kinase Akt has clinical relevance to radioresistance. However, its contributions to the DNA damage response, DNA double strand break (DSB) repair... 
COMET ASSAY | PATHWAY | PHOSPHORYLATION | MULTIDISCIPLINARY SCIENCES | PROSTATE-CANCER | PLECKSTRIN HOMOLOGY DOMAIN | DEPENDENT PROTEIN-KINASE | CHRONIC LYMPHOCYTIC-LEUKEMIA | IONIZING-RADIATION | INHIBITOR | HUMAN TUMOR-CELLS | DNA-Activated Protein Kinase - antagonists & inhibitors | T-Lymphocytes, Regulatory - metabolism | Epithelial Cells - metabolism | Apoptosis - drug effects | Heterocyclic Compounds, 3-Ring - pharmacology | Epithelial Cells - drug effects | Humans | Male | DNA Breaks, Double-Stranded | Prostate - metabolism | Proto-Oncogene Proteins c-akt - genetics | T-Lymphocytes, Regulatory - pathology | DNA-Binding Proteins - metabolism | Prostate - pathology | DNA End-Joining Repair | DNA-Activated Protein Kinase - genetics | DNA-Activated Protein Kinase - metabolism | Prostate - drug effects | Phosphorylation - drug effects | Chromones - pharmacology | Nuclear Proteins - genetics | Proto-Oncogene Proteins c-akt - metabolism | Fibroblasts - metabolism | DNA-Binding Proteins - antagonists & inhibitors | Morpholines - pharmacology | Epithelial Cells - pathology | Nuclear Proteins - metabolism | DNA - metabolism | Pyrimidines - pharmacology | DNA-Binding Proteins - genetics | Piperazines - pharmacology | DNA - genetics | Radiation Tolerance - drug effects | T-Lymphocytes, Regulatory - drug effects | Animals | Fibroblasts - drug effects | Nuclear Proteins - antagonists & inhibitors | Cell Line, Tumor | Fibroblasts - cytology | Mice | Protein Kinase Inhibitors - pharmacology | Mutation | Protein kinase C | AKT1 protein | Radiosensitivity | Cell survival | DNA damage | Irradiated | Radioresistance | AKT protein | Embryo fibroblasts | Double-strand break repair | Kinases | DNA repair | Survival | Mimicry | DNA-dependent protein kinase | Localization | Prostate | Prostate cancer | Deoxyribonucleic acid--DNA | Apoptosis | Tumors
Journal Article
PloS one, ISSN 1932-6203, 12/2016, Volume 11, Issue 12, p. e0167094
AS1411 binds nucleolin (NCL) and is the first oligodeoxynucleotide aptamer to reach phase I and II clinical trials for the treatment of several cancers.... 
GLIOBLASTOMA | PROTEIN | MESSENGER-RNA | AS1411 | DNA | MULTIDISCIPLINARY SCIENCES | APTAMER | TUMOR-GROWTH | CANCER | EXPRESSION | ADJUVANT TEMOZOLOMIDE | RNA-Binding Proteins - genetics | Apoptosis - drug effects | Humans | Middle Aged | Brain Neoplasms - pathology | Gene Expression Regulation, Neoplastic | Male | NF-kappa B - metabolism | Phosphoproteins - antagonists & inhibitors | Phosphoproteins - metabolism | Proto-Oncogene Proteins c-akt - genetics | Tumor Suppressor Protein p53 - genetics | Glioma - genetics | Proto-Oncogene Proteins c-bcl-2 - metabolism | G2 Phase Cell Cycle Checkpoints - drug effects | Glioma - pathology | Tumor Suppressor Protein p53 - agonists | Female | Antineoplastic Agents - pharmacology | Brain Neoplasms - mortality | Proto-Oncogene Proteins c-akt - metabolism | RNA-Binding Proteins - antagonists & inhibitors | Aptamers, Nucleotide - pharmacology | NF-kappa B - antagonists & inhibitors | Glioma - mortality | Signal Transduction | Tumor Suppressor Protein p53 - metabolism | Brain Neoplasms - genetics | Phosphoproteins - genetics | Brain Neoplasms - drug therapy | Mice, SCID | Xenograft Model Antitumor Assays | Animals | NF-kappa B - genetics | Survival Analysis | Cell Line, Tumor | Proto-Oncogene Proteins c-bcl-2 - antagonists & inhibitors | Cell Proliferation - drug effects | Mice | Oligodeoxyribonucleotides - pharmacology | Proto-Oncogene Proteins c-bcl-2 - genetics | Glioma - drug therapy | Proto-Oncogene Proteins c-akt - antagonists & inhibitors | RNA-Binding Proteins - metabolism | Gliomas | Physiological aspects | Development and progression | Genetic aspects | Research | Gene expression | Apoptosis | Cell proliferation | Regulations | Bcl-2 protein | p53 Protein | Brain cancer | Clinical trials | Neurosurgery | Cancer therapies | Nuclei | Proteins | Cell growth | Glioma cells | Animal tissues | Cell cycle | Xenografts | Inhibition | Deoxyribonucleic acid--DNA | nucleolin | Medical research | AKT1 protein | Astrocytes | Breast cancer | Hospitals | Medical prognosis | Aptamers | Nuclei (cytology) | Cell migration | Cytoplasm | Deoxyribonucleic acid
Journal Article
Angewandte Chemie International Edition, ISSN 1433-7851, 02/2016, Volume 55, Issue 6, pp. 2262 - 2266
Journal Article