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akt3 (163) 163
index medicus (118) 118
humans (104) 104
proto-oncogene proteins c-akt - genetics (57) 57
apoptosis (51) 51
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female (49) 49
proto-oncogene proteins c-akt - metabolism (49) 49
animals (42) 42
expression (41) 41
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akt1 (14) 14
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phosphatidylinositol 3-kinases - metabolism (14) 14
progression (14) 14
akt protein (13) 13
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akt (12) 12
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chromosomes, human, pair 1 (9) 9
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mirna (9) 9
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ACS Medicinal Chemistry Letters, ISSN 1948-5875, 10/2011, Volume 2, Issue 10, pp. 774 - 779
Phosphoinositide-3-kinases (PI3Ks) are important oncology targets due to the deregulation of this signaling pathway in a wide variety of human cancers. Herein... 
NVP-BKM120 | phosphoinositide-3-kinase | PI3K/AKT3 pathway | TARGET | RAPAMYCIN | 3-KINASES | CHEMISTRY, MEDICINAL | PATHWAY
Journal Article
Biochemical and Biophysical Research Communications, ISSN 0006-291X, 09/2019, Volume 517, Issue 3, pp. 532 - 537
MicroRNAs (miRNA) are reported to be a vital regulator of neuropathic pain. Even so, the molecular mechanisms of miRNA function on neuropathic pain development... 
microRNA-150 | AKT3 | Neuropathic pain
Journal Article
NATURE GENETICS, ISSN 1061-4036, 05/2014, Volume 46, Issue 5, pp. 510 - 515
Activating mutations in genes encoding phosphatidylinositol 3-kinase (PI3K)-AKT pathway components cause... 
NEOCORTEX | PIK3CA | AKT3 | GENETICS & HEREDITY | MICE | INTERMEDIATE PROGENITOR CELLS | CEREBRAL-CORTEX
Journal Article
Journal of Cellular Physiology, ISSN 0021-9541, 11/2019, Volume 234, Issue 11, pp. 21342 - 21351
Our findings revealed that dysregulation of miR‐15a and miR‐205 synergically contribute to the development of hemangioma by elevating AKT1/AKT3, and the miRNAs... 
hemangioma | proliferation | endothelial | miR‐205 | AKT1 | apoptosis | AKT3 miR‐15a | AKT3 miR-15a | miR-205 | PROPRANOLOL | PHYSIOLOGY | ANGIOGENESIS | MECHANISM | CELL BIOLOGY | BREAST-CANCER | MIR-16 | EXPRESSION | Hemangioma | MicroRNA | Analysis | Endothelium | Cell proliferation | AKT1 protein | Pathogenesis | Therapeutic applications | MiRNA | siRNA | Endothelial cells | Polymerase chain reaction | Transfection | MicroRNAs | Viability | PTEN protein | Apoptosis | Index Medicus
Journal Article
European Review for Medical and Pharmacological Sciences, ISSN 1128-3602, 09/2018, Volume 22, Issue 18, pp. 5972 - 5979
OBJECTIVE: To explore the role of microRNA-217 in non-small cell lung cancer (NSCLC) and its underlying mechanism. PATIENTS AND METHODS: MicroRNA-217... 
PI3K pathway | NSCLC | MicroRNA-217 | AKT3 | APOPTOSIS | METASTASIS | PROGNOSIS | PROLIFERATION | BREAST-CANCER | MIRNA EXPRESSION | MIR-145 | GASTRIC-CANCER | COLORECTAL-CANCER | PHARMACOLOGY & PHARMACY | TARGETING AKT3
Journal Article
by Jin, Y and Tao, LP and Yao, SC and Huang, QK and Chen, ZF and Sun, YJ and Jin, SQ
EUROPEAN REVIEW FOR MEDICAL AND PHARMACOLOGICAL SCIENCES, ISSN 1128-3602, 11/2017, Volume 21, Issue 22, pp. 5112 - 5120
OBJECTIVE: To dissect the functioning mode of miR-582-5p on gastric cancer cell growth and provide therapeutic targets for gastric cancer. PATIENTS AND... 
microRNAs | AKT3 | PHARMACOLOGY & PHARMACY | Proliferation | Gastric cancer | PROGRESSION
Journal Article
OncoTargets and Therapy, ISSN 1178-6930, 09/2019, Volume 12, pp. 7865 - 7875
Jianghong Hu,1,* Guohua Ni,2,* Ling Mao,2 Xianglong Xue,1 Jijie Zhang,2 Weixia Wu,2 Shaoru Zhang,3 Hong Zhao,3 Lifang Ding,2 Lihui Wang3 1Department of... 
MicroRNA-665 | Proliferation | CeRNA | LINC00565 | AKT3 | Apoptosis
Journal Article
Molecular Medicine Reports, ISSN 1791-2997, 02/2015, Volume 11, Issue 2, pp. 1378 - 1383
Journal Article
BRAIN, ISSN 0006-8950, 10/2017, Volume 140, pp. 2610 - 2622
Mutations of genes within the phosphatidylinositol-3-kinase (PI3K)-AKT-MTOR pathway are well known causes of brain overgrowth (megalencephaly) as well as... 
epilepsy | polymicrogyria | MCAP | SUDDEN-DEATH | megalencephaly | CORTICAL DEVELOPMENT | NEUROSCIENCES | BRAIN MALFORMATIONS | SOMATIC MUTATIONS | CLINICAL NEUROLOGY | HYPOINSULINEMIC HYPOKETOTIC HYPOGLYCEMIA | ACTIVATING MUTATION | hemimegalencephaly | AKT3 | PROTEUS-SYNDROME | DE-NOVO GERMLINE
Journal Article
Nature Genetics, ISSN 1061-4036, 08/2012, Volume 44, Issue 8, pp. 941 - 945
Journal Article
Nature Medicine, ISSN 1078-8956, 04/2015, Volume 21, Issue 4, pp. 395 - 400
Journal Article
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 08/2014, Volume 371, Issue 8, pp. 733 - 743
Journal Article
JOURNAL OF THROMBOSIS AND HAEMOSTASIS, ISSN 1538-7933, 07/2015, Volume 13, Issue 7, pp. 1335 - 1344
BackgroundHistone deacetylases (HDACs) play a key role in signaling in many cell types. However, little is known about the participation of HDACs, particularly... 
acetylation | CYTOSKELETAL | blood platelet | ACTIVATION | signal transduction | sirtuins | Akt3 protein kinase | PERIPHERAL VASCULAR DISEASE | HEMATOLOGY | SIRT1
Journal Article
Biochemical and Biophysical Research Communications, ISSN 0006-291X, 03/2019, Volume 510, Issue 3, pp. 479 - 486
Osteosarcoma (OS) has emerged as the most common primary musculoskeletal malignant tumor which affects children and adolescents. A growing number of relevant... 
MicroRNA-1258 | Proliferation | Osteosarcoma | AKT3 | Cell cycle | METASTASIS | BIOCHEMISTRY & MOLECULAR BIOLOGY | CANCER | HEPARANASE | INVASION | BIOPHYSICS | BIOGENESIS | PATHWAY | BIOLOGY | EXPRESSION | Medical colleges | Development and progression
Journal Article