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Cold Spring Harbor protocols, ISSN 1940-3402, 06/2019, Volume 2019, Issue 6, p. pdb.prot097808
In vitro oligonucleotide and polymerase chain reaction (PCR)-based mutagenesis is generally used for altering the nucleotide sequence of genes to study their... 
Alanine | RNA-directed DNA polymerase | Scanning | Nucleotide sequence | Scanning mutagenesis | Amino acid sequence | Amino acids | Viruses | Nucleotides | Proteins | Polymerase chain reaction | Mutagenesis | Human immunodeficiency virus--HIV
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 01/2018, Volume 115, Issue 2, p. E253
FoxP3+ regulatory T cells (Tregs) are a central element of immunological tolerance. FoxP3 is the key determining transcription factor of the Treg lineage,... 
Populations | Activation | Genomes | Lymphocytes T | Cofactors | Human populations | Immunology | Missense mutation | Lymphocytes | Transcription activation | Foxp3 protein | Deoxyribonucleic acid--DNA | CRISPR | Alanine | Immunoregulation | Scanning mutagenesis | T cell receptors | Immunological tolerance | Gene silencing | Immunosuppression | Variegation | Mutagenesis | Mice | Mutation | Colitis | Autoimmune diseases | Tumors
Journal Article
Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2016, Volume 140, Issue 1, pp. 232 - 241
Journal Article
Journal of Molecular Biology, ISSN 0022-2836, 2006, Volume 357, Issue 4, pp. 1283 - 1294
We describe here an alanine scanning mutational analysis of the Aβ(1-40) amyloid fibril monitored by fibril elongation thermodynamics derived from critical... 
proline | thermodynamics | hydrophobicity | alanine | amyloid | Proline | Thermodynamics | Alanine | Amyloid | Hydrophobicity | PROTEIN | SOLID-STATE NMR | ALZHEIMERS-DISEASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | PROLINE REPLACEMENT | BETA-SHEET | AMINO-ACIDS | SECONDARY STRUCTURE | PROTOFIBRILS | HYDROGEN-EXCHANGE | PARALLEL
Journal Article
The Journal of allergy and clinical immunology, ISSN 0091-6749, 7/2017, Volume 140, Issue 1, pp. 232 - 241
Reference database based on the alanine-scanning assay is a useful tool for evaluating unknown variations in STAT1. Gain-of-function alanine mutants occurred... 
alanine-scanning | mendelian susceptibility to mycobacterial disease | STAT1 | chronic mucocutaneous candidiasis | reference database
Journal Article
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 05/1997, Volume 272, Issue 20, pp. 12978 - 12983
Alanine scanning mutagenesis has been used to identify specific side chains of insulin which strongly influence binding to the insulin receptor. A total of 21... 
NEGATIVE COOPERATIVITY | SITE | AFFINITY | SIDE-CHAIN | K CQ BIOCHEMISTRY & MOLECULAR BIOLOGY | BIOCHEMISTRY & MOLECULAR BIOLOGY | BIOLOGICAL-ACTIVITY | AMINO-ACID-RESIDUES | RECEPTOR INTERACTIONS | BINDING | Amino Acid Sequence | Animals | Mutagenesis, Site-Directed | Alanine - genetics | Humans | Molecular Sequence Data | Mutation | Insulin - genetics
Journal Article
Molecular Medicine Reports, ISSN 1791-2997, 01/2018, Volume 17, Issue 1, pp. 1006 - 1014
The enterovirus 71 (EV71) SP70 epitope, derived from amino acids 208-222 of VP1, is a neutralizing epitope. The present study aimed to assess the inter-species... 
Alanine scanning | Enterovirus 71 | Foot and mouth disease | Sp71 epitope | Hand | Antibody affinity | MEDICINE, RESEARCH & EXPERIMENTAL | alanine scanning | TAIWAN | foot and mouth disease | antibody affinity | MONOCLONAL-ANTIBODY | SP71 epitope | FOOT | ONCOLOGY | MOUTH-DISEASE | enterovirus 71 | INFECTION | EPIDEMIC | hand | Index Medicus
Journal Article