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Cancer, ISSN 0008-543X, 12/2016, Volume 122, Issue 23, pp. 3641 - 3649
Journal Article
The Oncologist, ISSN 1083-7159, 02/2019, Volume 24, Issue 2, pp. 161 - e70
Lessons Learned Patients with hepatocellular carcinoma (HCC) often have limited therapeutic responses to the vascular endothelial growth factor (VEGF) tyrosine... 
ONCOLOGY | RECURRENT | ALK1 | Clinical Trial Results
Journal Article
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, ISSN 0027-8424, 07/2019, Volume 116, Issue 31, pp. 15570 - 15579
The type I TGF beta receptor TGF beta RI (encoded by Tgfbr1) was ablated in cartilage. The resulting Tgfbr1(Col2) mice exhibited lethal chondrodysplasia.... 
ACTIVATION | PROTEIN | BMP | CHONDROCYTES | MULTIDISCIPLINARY SCIENCES | cartilage | COMPONENTS | ALK5 | ALK1 | GROWTH-FACTOR-BETA | ARTICULAR-CARTILAGE | KINASE 1 ALK1 | DIFFERENTIATION | TGF beta | EXPRESSION | CHONDROGENESIS | Cartilage | Signaling | Growth plate | Intracellular signalling | Mice | Bone morphogenetic protein 9 | Ablation | Chondrodystrophy | Biological Sciences | PNAS Plus | TGFβ
Journal Article
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, ISSN 0027-8424, 09/2019, Volume 116, Issue 36, pp. 17800 - 17808
Journal Article
European Respiratory Journal, ISSN 0903-1936, 03/2019, Volume 53, Issue 3
Background: Heritable forms of pulmonary arterial hypertension (PAH) and pulmonary veno-occlusive disease/pulmonary capillary haemangiomatosis (PVOD/PCH)... 
EIF2AK4 MUTATIONS | GENE | RESPIRATORY SYSTEM | ARTERIAL-HYPERTENSION | GUIDELINES | RECEPTOR | COHORT | BMP9 | OUTCOMES | ALK1
Journal Article
Arteriosclerosis, Thrombosis, and Vascular Biology, ISSN 1079-5642, 10/2014, Volume 34, Issue 10, pp. 2232 - 2236
Journal Article
Blood, ISSN 0006-4971, 01/2008, Volume 111, Issue 2, pp. 478 - 478
TGFβ has been considered the most likely ALK1 ligand related to hemorrhagic telangiectasia (HHT). New research reports that TGFβR2 and ALK5 are not required... 
HEMATOLOGY | RECEPTOR | ALK1
Journal Article
Journal of Cell Biology, ISSN 0021-9525, 05/2018, Volume 217, Issue 5, pp. 1651 - 1665
Blood flow shapes vascular networks by orchestrating endothelial cell behavior and function. How endothelial cells read and interpret flow-derived signals is... 
ACTIVATION | EMBRYONIC-DEVELOPMENT | ZEBRAFISH | PROTEIN | FLUID | ANGIOGENESIS | FORCE | LAMINAR SHEAR-STRESS | BLOOD-FLOW | ALK1 | CELL BIOLOGY
Journal Article
Nature Communications, ISSN 2041-1723, 11/2016, Volume 7, Issue 1, p. 13247
Functional blood vessel growth depends on generation of distinct but coordinated responses from endothelial cells. Bone morphogenetic proteins (BMP), part of... 
PATHWAYS | PLATFORM | ZEBRAFISH | ANGIOGENESIS | RNA | BONE MORPHOGENETIC PROTEIN | MULTIDISCIPLINARY SCIENCES | ENDOTHELIAL-CELLS | GENE-EXPRESSION | KINASE 1 ALK1 | GROWTH-FACTOR
Journal Article
Biochemical Society Transactions, ISSN 0300-5127, 08/2016, Volume 44, Issue 4, pp. 1142 - 1149
Journal Article
Journal Article
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, ISSN 1079-5642, 12/2015, Volume 35, Issue 12, pp. 2626 - 2637
Objective Bone morphogenetic protein-9 (BMP9)/activin-like kinase-1 and delta-like 4 (DLL4)/Notch promote endothelial quiescence, and we aim to understand... 
ARTERIOVENOUS-MALFORMATIONS | ANGIOGENESIS | cell cycle | PHOSPHORYLATION | endothelial cell | Notch | NOTCH PATHWAY | BMP9 | ALK1 | DLL4 | CROSS-TALK | GROWTH | quiescence | PERIPHERAL VASCULAR DISEASE | LIGAND | HEMATOLOGY | UP-REGULATION
Journal Article
Journal Article
American Journal of Respiratory and Critical Care Medicine, ISSN 1073-449X, 04/2019, Volume 199, Issue 7, pp. 819 - 821
BMP9 (bone morphogenetic protein 9), a ligand of the TGF-ß (transforming growth factor-ß) superfamily that has a selective binding affinity to the BMPR2 (bone... 
PULMONARY | RESPIRATORY SYSTEM | BONE MORPHOGENETIC PROTEIN-9 | ALK1 | CRITICAL CARE MEDICINE | Proteins | Liver diseases | Homeostasis | Ligands | Mutation | Growth factors | Pulmonary hypertension
Journal Article
Archives of Pathology and Laboratory Medicine, ISSN 0003-9985, 01/2019, Volume 143, Issue 1, pp. 122 - 129
Context.-Inflammatory myofibroblastic tumor is a mesenchymal neoplasm of low malignant potential. It was first described in lung, but is known to occur in many... 
MEDICINE, RESEARCH & EXPERIMENTAL | PROTEIN | UTERUS | PLACENTA | PSEUDOTUMOR | MEDICAL LABORATORY TECHNOLOGY | PATHOLOGY | EXPRESSION | ALK1 | Endometrial cancer | Diagnosis | Research
Journal Article