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Indian journal of clinical biochemistry, ISSN 0974-0422, 2013, Volume 29, Issue 3, pp. 269 - 278
Alkaline phosphatase (ALP; E.C.3.I.3.1.) is an ubiquitous membrane-bound glycoprotein that catalyzes the hydrolysis of phosphate monoesters at basic pH values.... 
Life Sciences | Biochemistry, general | Pathology | Enzymes | Alkaline phosphatase | Placental alkaline phosphatase | Microbiology | Chemistry/Food Science, general | Isoenzymes | Intestinal alkaline phosphatase | L/B/K alkaline phosphatase | Liver alkaline phosphatase | Phosphates | Hydrolysis | Phosphatases | Glycoproteins | Biochemistry | Biocatalysts | Review | K alkaline phosphatase
Journal Article
The New England journal of medicine, ISSN 1533-4406, 2012, Volume 366, Issue 10, pp. 904 - 913
In this study of perinatal and infantile hypophosphatasia, patients received ENB-0040, a bone-targeted, recombinant, human tissue-nonspecific isozyme of... 
MEDICINE, GENERAL & INTERNAL | INFANTILE HYPOPHOSPHATASIA | GENE | NONSPECIFIC ALKALINE-PHOSPHATASE | DISEASE | MINERALIZATION | PYRIDOXAL-5'-PHOSPHATE | MURINE HYPOPHOSPHATASIA | BONE | INTRAVENOUS-INFUSION | TRANSPLANTATION | Recombinant Fusion Proteins - pharmacology | Rickets - diagnostic imaging | Humans | Recombinant Fusion Proteins - therapeutic use | Child, Preschool | Biological Availability | Infant | Male | Injections, Subcutaneous - adverse effects | Bone and Bones - drug effects | Enzyme Replacement Therapy - adverse effects | Bone and Bones - diagnostic imaging | Immunoglobulin G - pharmacology | Female | Infant, Newborn | Recombinant Fusion Proteins - administration & dosage | Alkaline Phosphatase - pharmacology | Immunoglobulin G - therapeutic use | Treatment Outcome | Immunoglobulin G - administration & dosage | Alkaline Phosphatase - therapeutic use | Hypophosphatasia - complications | Radiography | Rickets - drug therapy | Alkaline Phosphatase - administration & dosage | Hypophosphatasia - drug therapy | Infusions, Intravenous | Rickets - etiology | Enzymes | Care and treatment | Usage | Patient outcomes | Hypophosphatasia | Health aspects | Risk factors | Calcification (ectopic) | Alkaline phosphatase | Respiratory function | Cognitive ability | Infants | Bone diseases | Phosphatase | Rickets | Mineralization | Supplementation | Children | Osteomalacia | Parathyroid | Hypocalcemia | Age | Calcium (dietary) | Pharmacodynamics | Statistical analysis | Dietary supplements | Metabolism | Patients | Studies | Parathyroid hormone | Collaboration | Calcification | Plasma levels | Pharmacokinetics
Journal Article
Journal of bone and mineral research, ISSN 0884-0431, 2013, Volume 28, Issue 2, pp. 271 - 282
Tissue‐nonspecific alkaline phosphatase (TNAP) is expressed in mineralizing tissues and functions to reduce pyrophosphate (PPi), a potent inhibitor of... 
TISSUE‐NONSPECIFIC ALKALINE PHOSPHATASE (TNAP) | OSTEOPONTIN | MATRIX VESICLES | DENTIN | PYROPHOSPHATE | pyrophosphate | dentin | Tissue-nonspecific alkaline phosphatase (TNAP) | osteopontin | matrix vesicles | APPOSITIONAL MINERALIZATION | PERIODONTAL-LIGAMENT | TISSUE-NONSPECIFIC ALKALINE PHOSPHATASE (TNAP) | EXTRINSIC FIBER CEMENTUM | ALKALINE-PHOSPHATASE ACTIVITY | EXTRACELLULAR-MATRIX PROTEINS | ENZYME-REPLACEMENT THERAPY | CIRCUMPULPAL DENTIN | HYDROXYAPATITE FORMATION | INFANTILE HYPOPHOSPHATASIA | ENDOCRINOLOGY & METABOLISM | SKELETAL MINERALIZATION | Humans | Alkaline Phosphatase - metabolism | Osteopontin - metabolism | Dentin - pathology | Tooth Root - enzymology | Disease Models, Animal | Hypophosphatasia - pathology | Hypophosphatasia - genetics | Dentin - physiopathology | Enzyme Replacement Therapy | Odontoblasts - metabolism | Dentin - metabolism | Mice, Inbred C57BL | Gene Expression Regulation | Tooth Calcification | Dentin - ultrastructure | Hypophosphatasia - physiopathology | Tooth Root - pathology | Tooth Root - physiopathology | Phenotype | Animals | Organogenesis - genetics | Mice | Alkaline Phosphatase - deficiency | Odontoblasts - pathology | Immunohistochemistry | Phosphates | Phosphatases | Genes | Skin diseases | Arthritis | Skin | Universities and colleges | Dentin | Alkaline phosphatase | Animal models | Osteocalcin | Matrix vesicles | Dental roots | Teeth | Dspp protein | Molars | Hypophosphatasia | Pulp | Odontoblasts | Rickets | Mineralization | Dentinogenesis | Incisors | Differentiation | Osteomalacia | Cementum | Tissue-nonspecific alkaline phosphatase | TNAP
Journal Article
Proceedings of the National Academy of Sciences - PNAS, ISSN 1091-6490, 2013, Volume 110, Issue 17, pp. 7003 - 7008
Journal Article
Journal of neurochemistry, ISSN 0022-3042, 03/2017, Volume 140, Issue 6, pp. 919 - 940
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Journal Article
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