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1. Full Text From old alkylating agents to new minor groove binders
by Puyo, Stéphane and Montaudon, Danièle and Pourquier, Philippe
Critical reviews in oncology/hematology, ISSN 1040-8428, 2013, Volume 89, Issue 1, pp. 43 - 61
Hematology, Oncology and Palliative Medicine | O6-methylguanine | DNA adducts | DNA crosslinks | DNA repair | Alkylating agents | Oncology | Life Sciences & Biomedicine | Hematology | Science & Technology | Neoplasms - metabolism | Alkylating Agents - pharmacology | Humans | Antineoplastic Agents, Alkylating - pharmacology | Drug Resistance, Neoplasm | DNA - metabolism | Alkylation | Alkylating Agents - chemistry | Alkylating Agents - therapeutic use | Neoplasms - drug therapy | Antineoplastic Agents, Alkylating - therapeutic use | Alkylating Agents - metabolism | DNA - chemistry | Animals | Signal Transduction - drug effects | Antineoplastic Agents, Alkylating - chemistry | Antineoplastic Agents, Alkylating - metabolism | Drug approval | Index Medicus | Life Sciences
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2. Full Text Design, synthesis, nuclear localization, and biological activity of a fluorescent duocarmycin analog, HxTfA
by Kiakos, Konstantinos and Englinger, Bernhard and Yanow, Stephanie K and Wernitznig, Debora and Jakupec, Michael A and Berger, Walter and Keppler, Bernhard K and Hartley, John A and Lee, Moses and Patil, Pravin C
Bioorganic & medicinal chemistry letters, ISSN 0960-894X, 05/2018, Volume 28, Issue 8, pp. 1342 - 1347
Adenine-N3 | Antimalarial | Alkylating agent | Minor groove | Duocarmycins | Vaccine | Cytotoxic | Tafuramycin A | Benzimidazoles - toxicity | Fluorescent Dyes - chemical synthesis | Apoptosis - drug effects | Alkylating Agents - pharmacology | Humans | Fluorescent Dyes - metabolism | Indoles - chemical synthesis | Plasmodium falciparum - drug effects | Alkylating Agents - metabolism | Indoles - metabolism | Cell Nucleus - metabolism | Alkylating Agents - toxicity | Base Sequence | Drug Design | Fluorescent Dyes - pharmacology | Indoles - pharmacology | Antimalarials - chemical synthesis | A549 Cells | Antimalarials - metabolism | Benzimidazoles - chemical synthesis | Indoles - toxicity | Antimalarials - pharmacology | DNA - chemistry | Fluorescent Dyes - toxicity | Benzimidazoles - metabolism | Benzimidazoles - pharmacology | Antimalarials - toxicity | Alkylating Agents - chemical synthesis | Antimalarials | Research institutes | Malaria | DNA repair | Lung cancer | Index Medicus
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3. Full Text Pharmacokinetics of metronomic chemotherapy: A neglected but crucial aspect
by Bocci, Guido and Kerbel, Robert S
Nature reviews. Clinical oncology, ISSN 1759-4774, 11/2016, Volume 13, Issue 11, pp. 659 - 673
Life Sciences & Biomedicine | Oncology | Science & Technology | Angiogenesis Inhibitors - immunology | Pyrimidines - immunology | Antineoplastic Combined Chemotherapy Protocols - administration & dosage | Administration, Metronomic | Breast Neoplasms - immunology | Alkylating Agents - immunology | Humans | Antineoplastic Combined Chemotherapy Protocols - pharmacokinetics | Angiogenesis Inhibitors - administration & dosage | Clinical Trials, Phase III as Topic | Colorectal Neoplasms - drug therapy | Tubulin Modulators - administration & dosage | Alkylating Agents - pharmacokinetics | Camptothecin - administration & dosage | Female | Camptothecin - immunology | Camptothecin - pharmacokinetics | Pyrimidines - administration & dosage | Tubulin Modulators - pharmacokinetics | Alkylating Agents - administration & dosage | Antineoplastic Combined Chemotherapy Protocols - immunology | Breast Neoplasms - drug therapy | Forecasting | Randomized Controlled Trials as Topic | Immunity, Cellular - immunology | Colorectal Neoplasms - immunology | Tubulin Modulators - immunology | Pyrimidines - pharmacokinetics | Chemotherapy | Care and treatment | Patient outcomes | Forecasts and trends | Pharmacokinetics | Observations | Methods | Cancer | Index Medicus
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4. Full Text Balancing repair and tolerance of DNA damage caused by alkylating agents
by Fu, Dragony and Calvo, Jennifer A and Samson, Leona D
Nature reviews. Cancer, ISSN 1474-175X, 02/2012, Volume 12, Issue 2, pp. 104 - 120
Life Sciences & Biomedicine | Oncology | Science & Technology | Base Pair Mismatch | DNA Damage | Alkylating Agents - toxicity | DNA Repair | Humans | Care and treatment | Cell death | Alkylating agents | Patient outcomes | DNA damage | Dosage and administration | Genetic aspects | DNA mismatch repair | Cancer | Toxicity | Cytotoxicity | mismatch repair | Mutation | Base excision repair | Alkylation | epigenetics | Index Medicus
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5. Anticancer active illudins: Recent developments of a potent alkylating compound class
by Schobert, R and Knauer, S and Seibt, S and Biersack, B
Current medicinal chemistry, ISSN 0929-8673, 02/2011, Volume 18, Issue 6, pp. 790 - 807
Fungal agents | Anticancer drugs | Alkylating agents | Illudins | Irofulven | Pharmacology & Pharmacy | Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Chemistry, Medicinal | Science & Technology | Alkylating Agents - pharmacology | Antineoplastic Agents - chemical synthesis | Humans | Drug Discovery - methods | Alkylating Agents - isolation & purification | Antineoplastic Agents - chemistry | Spiro Compounds - isolation & purification | Alkylating Agents - chemistry | Animals | Antineoplastic Agents - isolation & purification | Spiro Compounds - chemical synthesis | Cell Line, Tumor | Antineoplastic Agents - pharmacology | Alkylating Agents - chemical synthesis | Spiro Compounds - chemistry | Spiro Compounds - pharmacology | Metabolism | Reviews | Cancer
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6. Nitrogen Mustards as Alkylating Agents: A Review on Chemistry, Mechanism of Action and Current USFDA Status of Drugs
by More, Ghansham S and Thomas, Asha B and Chitlange, Sohan S and Nanda, Rabindra K and Gajbhiye, Rahul L
Anti-cancer agents in medicinal chemistry, ISSN 1871-5206, 01/2019, Volume 19, Issue 9, pp. 1080 - 1102
Pharmacology & Pharmacy | Oncology | Life Sciences & Biomedicine | Chemistry, Medicinal | Science & Technology | Antineoplastic Agents, Alkylating - chemical synthesis | Nitrogen Mustard Compounds - chemical synthesis | Nitrogen Mustard Compounds - pharmacology | United States | Alkylating Agents - pharmacology | Humans | Antineoplastic Agents, Alkylating - pharmacology | Nitrogen Mustard Compounds - chemistry | Alkylating Agents - chemistry | Neoplasms - drug therapy | Cell Proliferation - drug effects | Antineoplastic Agents, Alkylating - chemistry | Neoplasms - pathology | Alkylating Agents - chemical synthesis | United States Food and Drug Administration
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7. Recent advances in targeted therapy for glioma
by Lin, Lin and Cai, Jinquan and Jiang, Chuanlu
Current medicinal chemistry, ISSN 0929-8673, 2017, Volume 24, Issue 13, pp. 1365 - 1381
Clinical trials | Glioma stem cell | Glioma | Targeted therapy | Cell signal transduction pathway | Immunotherapy | Pharmacology & Pharmacy | Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Chemistry, Medicinal | Science & Technology | Humans | Brain Neoplasms - pathology | Antibodies, Monoclonal - therapeutic use | Phosphatidylinositol 3-Kinases - metabolism | Stem Cells - cytology | Phosphatidylinositol 3-Kinases - antagonists & inhibitors | Stem Cells - metabolism | Brain Neoplasms - metabolism | Alkylating Agents - therapeutic use | Glioma - metabolism | Stem Cell Transplantation | Protein Kinase Inhibitors - chemistry | Alkylating Agents - toxicity | Glioma - pathology | Glioma - therapy | Angiogenesis Inhibitors - therapeutic use | Receptor Protein-Tyrosine Kinases - antagonists & inhibitors | Antibodies, Monoclonal - immunology | Receptor Protein-Tyrosine Kinases - metabolism | Alkylating Agents - chemistry | Angiogenesis Inhibitors - toxicity | Signal Transduction - drug effects | Protein Kinase Inhibitors - therapeutic use | Brain Neoplasms - therapy | Protein Kinase Inhibitors - toxicity | Angiogenesis Inhibitors - chemistry | Tyrosine | Brain | Epidermal growth factor receptors | Brain tumors | Brain cancer | MAP kinase | Raf protein | AKT protein | Radiation therapy | Patients | 1-Phosphatidylinositol 3-kinase | Receptors | Chemotherapy | Surgery | Stem cells | Protein-tyrosine kinase
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