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Nature Genetics, ISSN 1061-4036, 01/2002, Volume 30, Issue 1, pp. 41 - 47
Acute lymphoblastic leukemias carrying a chromosomal translocation involving the mixed-lineage leukemia gene (MLL, ALL1, HRX) have a particularly poor... 
HEMATOPOIETIC-CELLS | CHROMOSOME-TRANSLOCATION | FUSION | DROSOPHILA-TRITHORAX | ACUTE LYMPHOBLASTIC-LEUKEMIA | GENETICS & HEREDITY | CLINICAL CHARACTERISTICS | T(4-11)(Q21-Q23) | T(7-11)(P15-P15) | ACUTE MYELOID-LEUKEMIA | REARRANGEMENTS | Translocation, Genetic | Oligonucleotide Array Sequence Analysis | Humans | Oncogene Proteins, Fusion - biosynthesis | Hematopoietic Stem Cells - pathology | Gene Expression Profiling | Proto-Oncogenes | Gene Expression Regulation, Leukemic - genetics | Leukemia, Myeloid - classification | RNA, Messenger - biosynthesis | Neoplastic Stem Cells - metabolism | Neoplastic Stem Cells - pathology | Neoplasm Proteins - genetics | Precursor Cell Lymphoblastic Leukemia-Lymphoma - pathology | Genes, Homeobox | Acute Disease | Homeodomain Proteins - biosynthesis | Histone-Lysine N-Methyltransferase | Neoplasm Proteins - biosynthesis | RNA, Messenger - genetics | Immunophenotyping | Hematopoietic Stem Cells - metabolism | DNA-Binding Proteins - genetics | Homeodomain Proteins - genetics | Precursor Cell Lymphoblastic Leukemia-Lymphoma - genetics | Cell Lineage | RNA, Neoplasm - biosynthesis | Oncogene Proteins, Fusion - genetics | RNA, Neoplasm - genetics | Myeloid-Lymphoid Leukemia Protein | Transcription Factors | Precursor Cell Lymphoblastic Leukemia-Lymphoma - classification | Control | Translocation (Genetics) | Physiological aspects | Genetic aspects | Acute lymphocytic leukemia | Research | Gene expression | Risk factors | HOX gene | ALL1 gene | HRX gene | MLL gene
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 4/2000, Volume 97, Issue 9, pp. 4790 - 4795
Journal Article
Journal Article
Proceedings of the National Academy of Sciences, USA, ISSN 0027-8424, 05/2011, Volume 108, Issue 19, pp. 7956 - 7961
Rearrangements of the MLL (ALL1) gene are very common in acute infant and therapy-associated leukemias. The rearrangements underlie the generation of MLL... 
Cell proliferation | Cell culture | ALL1 gene | Leukemia | Infants | SDF-1 protein | CXCR4 protein | Homeobox | MLL protein | Lymphocytes B | Bone marrow | gene rearrangement | Fusion protein | Cell migration | Colonization | Oncogenes
Journal Article
Journal Article
Journal Article
Journal Article
Blood, ISSN 0006-4971, 2000, Volume 96, Issue 13, pp. 4360 - 4362
The partner gene of MLL was identified in a patient with treatment-related acute myeloid leukemia in which the karyotype suggested t(3;11)(q25;q23). Prior... 
AML1 GENE | ALL1 GENE | DOMAIN | THERAPY | FUSION | BIOCHEMICAL-CHARACTERIZATION | HEMATOLOGY | EXPRESSION | SECONDARY LEUKEMIAS | CHILDREN | Cyclophosphamide - administration & dosage | Humans | DNA, Complementary - genetics | Antineoplastic Combined Chemotherapy Protocols - adverse effects | Child, Preschool | Molecular Sequence Data | Male | Transplantation, Autologous | Neuroblastoma - therapy | Cyclophosphamide - adverse effects | Whole-Body Irradiation - adverse effects | Teniposide - adverse effects | Chromosomes, Human, Pair 3 - ultrastructure | Bone Marrow Transplantation | Fatal Outcome | Polymerase Chain Reaction | Vincristine - administration & dosage | Leukemia, Radiation-Induced - genetics | Transplantation Conditioning - adverse effects | Neoplasms, Second Primary - genetics | Leukemia, Myelomonocytic, Acute - etiology | Doxorubicin - administration & dosage | Leukemia, Myelomonocytic, Acute - genetics | Chromosomes, Human, Pair 11 - ultrastructure | Leukemia, Radiation-Induced - etiology | Neoplasm Recurrence, Local | Chromosomes, Human, Pair 11 - genetics | Combined Modality Therapy | Teniposide - administration & dosage | Neoplasms, Second Primary - etiology | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Oncogene Proteins, Fusion - genetics | Neuroblastoma - drug therapy | Neuroblastoma - radiotherapy | Vincristine - adverse effects | Myeloid-Lymphoid Leukemia Protein | DNA, Neoplasm - genetics | Chromosomes, Human, Pair 3 - genetics | Doxorubicin - adverse effects | Translocation, Genetic - genetics
Journal Article
Genes, Chromosomes and Cancer, ISSN 1045-2257, 10/2000, Volume 29, Issue 2, pp. 180 - 185
Journal Article
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