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1996, Current topics in microbiology and immunology, ISBN 3540593446, Volume 205., x, 182
Book
Journal of Neuroimmunology, ISSN 0165-5728, 2015, Volume 283, pp. 50 - 57
Abstract Alzheimer's disease (EOAD, LOAD), mild cognitive impairment (MCI), Parkinson's disease (PD) and healthy controls were included to determine the serum... 
Neurology | Allergy and Immunology | Brain derived neurotrophic factor (BDNF) | Heat shock protein 90 (Hsp90) | Interleukin 1 beta (IL-1β) | Interleukin 6 (IL-6) | Biomarker | Interleukin 10 (IL-10) | Mild cognitive impairment (MCI) | Parkinson's disease (PD) | Tumor necrosis factor alpha (TNFα) | Interleukin 1 alpha (IL-1α) | Alpha-2 macroglobulin (α2-macroglobulin) | Alzheimer's disease | Tumor necrosis factor alpha (TNF alpha) | CYTOKINES | ALPHA-ANTICHYMOTRYPSIN | NECROSIS-FACTOR-ALPHA | IMMUNOLOGY | CEREBROSPINAL-FLUID | NEUROSCIENCES | INFLAMMATORY MARKERS | VASCULAR DEMENTIA | Interleukin 1 alpha (IL-1 alpha) | PLASMA-LEVELS | IL-1-BETA | TNF-ALPHA | Alpha-2 macroglobulin (alpha 2-macroglobulin) | Interleukin 1 beta (IL-1 beta) | BRAIN | Enzyme-Linked Immunosorbent Assay | Parkinson Disease - immunology | Humans | Middle Aged | Male | Brain-Derived Neurotrophic Factor - blood | Cognitive Dysfunction - blood | Inflammation | Biomarkers - blood | Interleukin-1alpha - blood | Interleukin-1beta - blood | Cognitive Dysfunction - immunology | Interleukin-6 - blood | Age of Onset | Aged, 80 and over | Alzheimer Disease - epidemiology | Female | Aged | Parkinson Disease - blood | Alzheimer Disease - immunology | alpha-Macroglobulins - analysis | Alzheimer Disease - blood | Care and treatment | Interleukins | Analysis | Index Medicus
Journal Article
2010, 1st ed., Progress in brain research, ISBN 9780444536136, Volume 187., 2 v.
Book
1992, ISBN 0824785541, Volume 56., xv, 600 p. : ill. ; 24 cm.
Book
1990, ISBN 0195054849, xv, 397
Book
Journal of Clinical Investigation, ISSN 0021-9738, 12/2010, Volume 120, Issue 12, pp. 4236 - 4250
Journal Article
Circulation Research, ISSN 0009-7330, 02/2014, Volume 114, Issue 4, pp. 677 - 688
RATIONALE:Evidence is increasing of a link between interferon (IFN) and pulmonary arterial hypertension (PAH). Conditions with chronically elevated endogenous... 
SURVIVAL | systemic | LUNG | CARDIAC & CARDIOVASCULAR SYSTEMS | chemokine CXCL10 | VIRUS | scleroderma | CHRONIC HEPATITIS-C | ALPHA | RECEPTOR | IFNAR1 subunit | SYSTEMIC-SCLEROSIS | interferon alpha-beta receptor | inflammation | interferon type I | ENDOTHELIAL-CELLS | DISEASE | PERIPHERAL VASCULAR DISEASE | SMOOTH-MUSCLE-CELLS | endothelin-1 | HEMATOLOGY | pulmonary arterial hypertension | Interferon-alpha - pharmacology | Interferon-beta - immunology | Humans | Male | Lung - cytology | Signal Transduction - immunology | Chemokine CXCL10 - immunology | Receptor, Interferon alpha-beta - genetics | Organ Culture Techniques | Disease Models, Animal | Receptor, Interferon alpha-beta - metabolism | Interferon-alpha - metabolism | Endothelin-1 - metabolism | Mice, Inbred C57BL | Scleroderma, Systemic - metabolism | Cells, Cultured | Familial Primary Pulmonary Hypertension | Hypertension, Pulmonary - immunology | Hypertension, Pulmonary - metabolism | Scleroderma, Systemic - immunology | Interferon-alpha - immunology | Mice, Knockout | Endothelial Cells - immunology | Endothelin-1 - immunology | Animals | Interferon-beta - metabolism | Interferon-beta - pharmacology | Receptor, Interferon alpha-beta - immunology | Endothelial Cells - cytology | Interferon-gamma - immunology | Mice | Chemokine CXCL10 - metabolism | Interferon-gamma - pharmacology | Index Medicus | scleroderma, systemic | IFNAR1 subunit, interferon alpha-beta receptor
Journal Article
FASEB Journal, ISSN 0892-6638, 02/2013, Volume 27, Issue 2, pp. 832 - 842
Pasteurella multocida is the causative agent of a number of epizootic and zoonotic diseases. Its major virulence factor associated with atrophic rhinitis in... 
Helical domain | GTPase domain | Deamidation | Oncogene | PMT | MITOGENIC TOXIN | ACTIVATION | G-ALPHA | CRYSTAL-STRUCTURE | BIOCHEMISTRY & MOLECULAR BIOLOGY | INVOLVEMENT | helical domain | oncogene | CANCER | RHOA | CELL BIOLOGY | deamidation | GROWTH | BIOLOGY | GTPASE | GTP-Binding Protein alpha Subunits, Gi-Go - genetics | GTP-Binding Protein alpha Subunits - chemistry | Humans | DNA, Complementary - genetics | Bacterial Toxins - toxicity | Molecular Sequence Data | Substrate Specificity | Recombinant Fusion Proteins - metabolism | GTP-Binding Protein alpha Subunits, Gi-Go - chemistry | Bacterial Proteins - toxicity | GTP-Binding Protein alpha Subunits, Gq-G11 - chemistry | Pasteurella multocida - metabolism | Base Sequence | HEK293 Cells | Bacterial Toxins - genetics | Glutamine - chemistry | GTP-Binding Protein alpha Subunits, Gq-G11 - metabolism | Binding Sites | Peptide Fragments - genetics | Amino Acid Sequence | GTP-Binding Protein alpha Subunits, Gq-G11 - genetics | Peptide Fragments - metabolism | GTP-Binding Protein alpha Subunits - metabolism | Mutagenesis, Site-Directed | Bacterial Proteins - genetics | Cells, Cultured | GTP-Binding Protein alpha Subunits - genetics | Pasteurella multocida - genetics | Recombinant Fusion Proteins - chemistry | Mice, Knockout | Sequence Homology, Amino Acid | Pasteurella multocida - pathogenicity | Bacterial Toxins - metabolism | Peptide Fragments - chemistry | Animals | Signal Transduction - drug effects | Recombinant Fusion Proteins - genetics | Bacterial Proteins - metabolism | GTP-Binding Protein alpha Subunits - deficiency | Mice | GTP-Binding Protein alpha Subunits, Gi-Go - metabolism | Amino Acid Substitution | Index Medicus | Research Communications
Journal Article
Clinical Cancer Research, ISSN 1078-0432, 12/2010, Volume 16, Issue 24, pp. 6139 - 6149
Purpose: A novel nanomedicine, CYT-6091, constructed by simultaneously binding recombinant human tumor necrosis factor alpha (rhTNF) and thiolyated... 
TRIAL | TUMOR-NECROSIS-FACTOR | INTERFERON-GAMMA | ONCOLOGY | RTNF-ALPHA | ADVANCED MALIGNANT DISEASE | TNF-ALPHA | ISOLATED LIMB PERFUSION | MELPHALAN | SOFT-TISSUE SARCOMA | FACTOR-ALPHA | Neoplasms - metabolism | Injections, Intravenous | Nanoparticles - chemistry | Gold Colloid - administration & dosage | Humans | Middle Aged | Polyethylene Glycols - adverse effects | Male | Polyethylene Glycols - chemistry | Recombinant Proteins - pharmacokinetics | Antineoplastic Agents - administration & dosage | Recombinant Proteins - adverse effects | Dose-Response Relationship, Drug | Young Adult | Gold Colloid - pharmacokinetics | Antineoplastic Agents - adverse effects | Aged, 80 and over | Adult | Female | Antineoplastic Agents - pharmacokinetics | Polyethylene Glycols - pharmacokinetics | Recombinant Proteins - chemistry | Gold Colloid - adverse effects | Gold Colloid - chemistry | Antineoplastic Agents - chemistry | Polyethylene Glycols - administration & dosage | Recombinant Proteins - administration & dosage | Neoplasms - drug therapy | Maximum Tolerated Dose | Tumor Necrosis Factor-alpha - adverse effects | Tumor Necrosis Factor-alpha - chemistry | Adolescent | Tumor Necrosis Factor-alpha - administration & dosage | Aged | Nanoparticles - administration & dosage | Tumor Necrosis Factor-alpha - pharmacokinetics | Neoplasms - pathology | Index Medicus
Journal Article
EMBO Molecular Medicine, ISSN 1757-4676, 03/2013, Volume 5, Issue 3, pp. 397 - 412
Alpha‐1‐anti‐trypsin deficiency is the most common genetic cause of liver disease in children and liver transplantation is currently the only available... 
TFEB | gene therapy | alpha‐1‐anti‐trypsin | autophagy | helper‐dependent adenoviral vector | Alpha-1-anti-trypsin | Helper-dependent adenoviral vector | Gene therapy | Autophagy | NONHUMAN-PRIMATES | MEDICINE, RESEARCH & EXPERIMENTAL | DEPENDENT ADENOVIRAL VECTORS | ALPHA-ANTITRYPSIN DEFICIENCY | LIVER-DISEASE | helper-dependent adenoviral vector | TRANSGENE EXPRESSION | alpha-1-anti-trypsin | HEMOPHILIA-B | ENDOPLASMIC-RETICULUM | ALPHA-1-ANTITRYPSIN DEFICIENCY | NF-KAPPA-B | MUTANT ALPHA-ANTITRYPSIN-Z | Liver - pathology | Liver - enzymology | Microtubule-Associated Proteins - genetics | Humans | NF-kappa B - metabolism | Mutation, Missense | Lysosomes - metabolism | Transfection | Time Factors | Liver Cirrhosis - metabolism | Autophagy - genetics | Microtubule-Associated Proteins - deficiency | Interleukin-6 - metabolism | Liver Cirrhosis - genetics | Disease Models, Animal | alpha 1-Antitrypsin Deficiency - genetics | Gene Transfer Techniques | Genetic Predisposition to Disease | alpha 1-Antitrypsin - genetics | alpha 1-Antitrypsin Deficiency - therapy | Mice, Inbred C57BL | Mice, Transgenic | Liver Cirrhosis - therapy | alpha 1-Antitrypsin Deficiency - metabolism | Mice, Knockout | Papio | Autophagy-Related Protein 7 | Phenotype | Animals | alpha 1-Antitrypsin Deficiency - complications | Basic Helix-Loop-Helix Leucine Zipper Transcription Factors - genetics | Liver Cirrhosis - pathology | Basic Helix-Loop-Helix Leucine Zipper Transcription Factors - metabolism | Mice | alpha 1-Antitrypsin - metabolism | HeLa Cells | Apoptosis | Genetic Therapy - methods | Proteins | Trypsin | Liver diseases | Genes | Genetic engineering | Genetic transcription | Health aspects | Gene expression | Index Medicus
Journal Article