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An inhibition ELISA to determine alpha macroglobulin levels in mouse plasma, 12/1994
A sensitive method for quantifying mouse plasma alpha- macroglobulins (AM) using an inhibition ELISA is described. AM are important plasma proteinase... 
alpha-2-macroglobulin - A2M - ELISA - murinoglobulin
Journal
Archives of Biochemistry and Biophysics, ISSN 0003-9861, 10/2019, Volume 675, p. 108118
Methotrexate (MTX) is advised in the treatment of solid tumours, hematologic malignancies and autoimmune disorders. On reaching the circulation, 60% of MTX is... 
Alpha-2-macroglobulin | Anticancer drug | Reactive oxygen species | Methotrexate | Antiproteinase
Journal Article
11/2009
Surfactant protein D (SP-D) is an important innate immune collectin involved in uptake and clearance of microbes and allergens in the lungs. SP-D has been... 
Surfactant Protein D | 0982 | Innate Immunity | Alpha-2-Macroglobulin | 0307
Dissertation
Journal of Nutrition, ISSN 0022-3166, 2015, Volume 145, Issue 6, pp. 1256 - 1262
Journal Article
BMB Reports, ISSN 1976-6696, 2013, Volume 46, Issue 12, p. 582
Adipocyte differentiation is a complex developmental process forming adipocytes from various precursor cells. The murine 3T3-L1 preadipocyte cell line has been... 
Adipocyte | Alpha-2-macroglobulin | Serum | Paraoxonase | Differentiation
Journal Article
by Huangfu, C and Ma, Y and Jia, J and Lv, M and Zhu, F and Ma, X and Zhao, X and Zhang, J
TRANSFUSION MEDICINE, ISSN 0958-7578, 08/2017, Volume 27, Issue 4, pp. 309 - 311
Journal Article
JOURNAL OF NEUROSCIENCE, ISSN 0270-6474, 08/2016, Volume 36, Issue 34, pp. 8826 - 8841
In many diseases, expression and ligand-dependent activity of the p75(NTR) receptor can promote pericyte and vascular dysfunction, inflammation, glial... 
OPTICAL COHERENCE TOMOGRAPHY | neurodegeneration | DEATH | NEUROSCIENCES | NERVE GROWTH-FACTOR | DEGENERATION | RETINAL GANGLION-CELLS | receptor | retina | pathophysiology | IN-VIVO | NEURONS | neurotrophin | ALPHA-2-MACROGLOBULIN | GLAUCOMA | GLIA | diabetes
Journal Article
by Ning, JH and Li, Y and Cui, ZX
AQUACULTURE, ISSN 0044-8486, 08/2019, Volume 510, pp. 9 - 21
Thioester-containing proteins (TEPs) are an ancient superfamily of secreted effector proteins that perform essential roles in the innate immune response.... 
DEFENSE | Portunus trituberculatus | AMP | SPIDER | PROTEASES | FISHERIES | EVOLUTION | GENE | MARINE & FRESHWATER BIOLOGY | Expression profiles | MOLECULAR-CLONING | ALPHA-2-MACROGLOBULIN | COMPLEMENT-LIKE PROTEIN | TEP | Phagocytosis | CRUSTACEAN | Prophenoloxidase system
Journal Article
JOURNAL OF CLINICAL INVESTIGATION, ISSN 0021-9738, 12/2000, Volume 106, Issue 12, pp. 1489 - 1499
Elimination of amyloid-beta peptide (A beta) from the brain is poorly understood. After intracerebral microinjections in young mice,I-125-A beta (1.40) was... 
MEDICINE, RESEARCH & EXPERIMENTAL | CELL MONOLAYER | APOLIPOPROTEIN-J | HUMAN PLASMA | DOWNS-SYNDROME | AMYLOID-BETA-PEPTIDE | DISEASE | PRECURSOR PROTEIN | CEREBROSPINAL-FLUID | ALPHA-2-MACROGLOBULIN RECEPTOR | TRANSGENIC MICE
Journal Article
NEUROBIOLOGY OF AGING, ISSN 0197-4580, 02/2014, Volume 35, Issue 2, pp. 357 - 364
Low cerebrospinal fluid (CSF) A beta(42) levels correlate with increased brain Ab deposition in Alzheimer's disease (AD), which suggests a disruption in the... 
ARGYROPHILIC GRAIN DISEASE | BETA-SECRETASE ACTIVITY | AMYLOID FORMATION | ALZHEIMERS-DISEASE | CLINICAL-DIAGNOSIS | CANDIDATE GENES | Cerebrospinal fluid | NEUROSCIENCES | ALPHA-2-MACROGLOBULIN GENE | APOLIPOPROTEIN-E | GERIATRICS & GERONTOLOGY | PLASMA BIOMARKERS | A beta | alpha-2-Macroglobulin | APOE | A2M | Alzheimer's disease | GAMMA-SECRETASE
Journal Article
Journal Article
PLOS PATHOGENS, ISSN 1553-7366, 07/2015, Volume 11, Issue 7
Rosetting, the adhesion of Plasmodium falciparum-infected erythrocytes to uninfected erythrocytes, involves clonal variants of the parasite protein P.... 
HUMAN ALPHA-2-MACROGLOBULIN | ROSETTE FORMATION | MICROBIOLOGY | INFECTED ERYTHROCYTES | IN-VITRO | COMPLEX-FORMATION | VIROLOGY | AFRICAN CHILDREN | ENDOTHELIAL-CELLS | GROUP-G STREPTOCOCCI | MALARIA PARASITE | PARASITOLOGY | CEREBRAL MALARIA
Journal Article
Scientific Reports, ISSN 2045-2322, 12/2019, Volume 9, Issue 1, pp. 4340 - 13
Non-genetic MMP-2 insufficiency is a relatively unexplored condition which could be induced by pathological overexpression of endogenous MMP-2 inhibitors such... 
CLUSPRO | MATRIX METALLOPROTEINASES | GELATINASE-A | MECHANISM | MULTIDISCIPLINARY SCIENCES | MUTATION | EXTRACELLULAR-MATRIX | MULTICENTRIC OSTEOLYSIS | ALPHA-2-MACROGLOBULIN | PLATELET ACTIVATION | WEB SERVER | a2-Macroglobulin | Gelatin | Fluorescein | Fibrinogen | Arthritis | Gelatinase B | Gelatinase A
Journal Article
JOURNAL OF PROTEOME RESEARCH, ISSN 1535-3893, 12/2015, Volume 14, Issue 12, pp. 5131 - 5143
Initial triggers for diabetic retinopathy (DR) are hyperglycemia-induced oxidative stress and advanced glycation end-products. The most pathological structural... 
RENIN-ANGIOTENSIN | apolipoproteins | MANAGEMENT | PROTEIN | complement system | BIOCHEMICAL RESEARCH METHODS | ELEVATION | vitreous humor | diabetic retinopathy | LUMICAN | BIOMARKERS | coagulation cascade | MACULAR EDEMA | INFLAMMATION | label-free quantification | ALPHA-2-MACROGLOBULIN | INHIBITORS | quantitative proteomics
Journal Article
SCIENTIFIC REPORTS, ISSN 2045-2322, 09/2019, Volume 9
alpha(2)-Macroglobulin is a highly abundant serum protein involved in the development of atherosclerosis and cardiac hypertrophy. However, its circulating... 
MORTALITY | URINARY ALBUMIN EXCRETION | ENDOTHELIAL DYSFUNCTION | ALZHEIMERS-DISEASE | MULTIDISCIPLINARY SCIENCES | CARDIAC ISOFORM | CARDIOVASCULAR-DISEASE | FOLLOW-UP | CLINICAL CHARACTERISTICS | ALPHA-2-MACROGLOBULIN LEVELS | VASCULAR-DISEASE
Journal Article
THROMBOSIS AND HAEMOSTASIS, ISSN 0340-6245, 09/2018, Volume 118, Issue 9, pp. 1535 - 1544
Increasing number of patients are treated with direct oral anticoagulants (DOAC). An antidote for dabigatran inhibiting thrombin (idarucizumab) is available... 
ANDEXANET ALPHA | ACTIVATION | COAGULATION-FACTOR-XA | oral anticoagulant | HUMAN ALPHA-MACROGLOBULIN | ALPHA-MACROGLOBULIN COMPLEXES | rivaroxaban | apixaban | REVERSAL | 3-DIMENSIONAL STRUCTURE | DABIGATRAN | antidote | PERIPHERAL VASCULAR DISEASE | ALPHA-2-MACROGLOBULIN | HEMATOLOGY
Journal Article
MOLECULAR AND CELLULAR BIOLOGY, ISSN 0270-7306, 05/2008, Volume 28, Issue 10, pp. 3344 - 3358
Jump-starting and subsequently maintaining epidermal and dermal cell migration are essential processes for skin wound healing. These events are often disrupted... 
SIGNAL-TRANSDUCTION | HEAT-SHOCK PROTEINS | HSP90 | COMPLEX | CALRETICULIN | BIOCHEMISTRY & MOLECULAR BIOLOGY | IN-VIVO | EXOSOMES | SURFACE | ALPHA-2-MACROGLOBULIN RECEPTOR | MOTILITY | CELL BIOLOGY
Journal Article
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