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plectin (40) 40
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by Cao, L and Xu, J
HUMAN PATHOLOGY, ISSN 0046-8177, 03/2017, Volume 61, pp. 222 - 223
Journal Article
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, ISSN 0027-8424, 03/2017, Volume 114, Issue 12, pp. E2337 - E2346
Neoplastic cells within individual carcinomas often exhibit considerable phenotypic heterogeneity in their epithelial versus mesenchymal-like cell states.... 
SURVIVAL | PREDICTOR | ITGB4 | MARKER | MULTIDISCIPLINARY SCIENCES | PHENOTYPE | HUMAN BREAST-CANCER | EMT | TUMORS | SLUG | heterogeneity | TRANSITION | mesenchymal | ALPHA-6-BETA-4 | cancer | EXPRESSION
Journal Article
HEPATOLOGY, ISSN 0270-9139, 12/2016, Volume 64, Issue 6, pp. 2103 - 2117
In patients with hepatocellular carcinoma (HCC) receiving sorafenib, drug resistance is common. HCC develops in a microenvironment enriched with extracellular... 
MIGRATION | INVASION | LAMININ GAMMA-2 | PROGNOSIS | ALPHA-3-BETA-1 INTEGRIN | ALPHA-6-BETA-4 | STROMA | CHEMORESISTANCE | GASTROENTEROLOGY & HEPATOLOGY | CANCER | EXPRESSION
Journal Article
NATURE COMMUNICATIONS, ISSN 2041-1723, 08/2016, Volume 7
Matrix stiffening is a prominent feature of pulmonary fibrosis. In this study, we demonstrate that matrix stiffness regulates the ability of fibrotic lung... 
MATRIX METALLOPROTEINASES | ALPHA-6-BETA-4 INTEGRIN | ACTIVATION | MULTIDISCIPLINARY SCIENCES | RHO-KINASE | P38 MAPK | EXTRACELLULAR-MATRIX | CELL MIGRATION | DIFFERENTIATION | EXPRESSION | PULMONARY-FIBROSIS
Journal Article
HUMAN PATHOLOGY, ISSN 0046-8177, 03/2017, Volume 61, pp. 223 - 224
Journal Article
Journal of Investigative Dermatology, ISSN 0022-202X, 09/2019, Volume 139, Issue 9, pp. 1876 - 1888.e4
Hemidesmosomes anchor the epidermal keratin filament cytoskeleton to the extracellular matrix. They are crucial for the mechanical integrity of skin. Their... 
ORGANIZATION | ALPHA-6-BETA-4 INTEGRIN | PROTEIN | ACTIN | CELL-MIGRATION | LAMININ-5 | MOLECULAR ARCHITECTURE | DYNAMICS | ALPHA-3-BETA-1 | SUBUNIT | DERMATOLOGY | Index Medicus
Journal Article
AMERICAN JOURNAL OF PATHOLOGY, ISSN 0002-9440, 12/2010, Volume 177, Issue 6, pp. 2791 - 2803
Adipose tissue secretes adipocytokines for energy homeostasis but recent evidence indicates that some adipocytokines also have a profound local impact on wound... 
ALPHA-6-BETA-4 INTEGRIN | REPAIR | PROTEIN | METASTASIS | INHIBITION | CELL-MIGRATION | IN-VIVO | KINASE | INDUCED ADIPOSE FACTOR | PATHOLOGY | EXPRESSION
Journal Article
JOURNAL OF MEDICINAL CHEMISTRY, ISSN 0022-2623, 07/2017, Volume 60, Issue 13, pp. 5826 - 5833
alpha 3 beta 4 nAChRs have been implicated in various pathophysiological conditions. However, the expression profile of alpha 3 beta 4 nAChRs and alpha 6/alpha... 
CHEMISTRY, MEDICINAL | CONUS-TEXTILE | ANTAGONIST | REGIIA | ALPHA-6-BETA-4 | TARGETS | DIVERSITY | MICE | NOREPINEPHRINE RELEASE | DISCOVERY | DEPENDENCE
Journal Article
Molecular Cancer Research, ISSN 1541-7786, 08/2018, Volume 16, Issue 8, pp. 1319 - 1331
Journal Article
MOLECULAR & CELLULAR PROTEOMICS, ISSN 1535-9476, 02/2019, Volume 18, Issue 2, pp. 277 - 293
Integrin-mediated laminin adhesions mediate epithelial cell anchorage to basement membranes and are critical regulators of epithelial cell polarity. Integrins... 
CYTOPLASMIC DOMAIN | ADHESION | CELLS | COMPLEX | BETA-4 | POLARITY | INTEGRIN ALPHA-6-BETA-4 | HEMIDESMOSOMES | BIOCHEMICAL RESEARCH METHODS | ARCHITECTURE | PROTEINS
Journal Article
Nature Materials, ISSN 1476-1122, 06/2014, Volume 13, Issue 10, pp. 970 - 978
Journal Article
Nature, ISSN 0028-0836, 02/2003, Volume 421, Issue 6923, pp. 639 - 643
The nuclear factor NF-κB and oncogenic Ras can alter proliferation in epidermis, the most common site of human cancer. These proteins are implicated in... 
APOPTOSIS | ACTIVATION | CARCINOGENESIS | LAMININ-5 | MULTIDISCIPLINARY SCIENCES | ALPHA-6-BETA-4 | SUBUNITS | SKIN | SQUAMOUS-CELL CARCINOMAS | HUMAN BREAST-CANCER | EXPRESSION
Journal Article
PLOS ONE, ISSN 1932-6203, 05/2015, Volume 10, Issue 5
Curcumin has been shown to mitigate cancer phenotypes such as invasive migration, proliferation, and survival by disrupting numerous signaling pathways. Our... 
INVASION | MECHANISM | PHOSPHORYLATION | MOBILIZATION | HEMIDESMOSOMES | MULTIDISCIPLINARY SCIENCES | ALPHA-6-BETA-4 | PROTEIN PALMITOYLATION | S-ACYLTRANSFERASES | TETRAHYDROCURCUMIN | PROGRESSION
Journal Article
JOURNAL OF INVESTIGATIVE DERMATOLOGY, ISSN 0022-202X, 06/2015, Volume 135, Issue 6, pp. 1609 - 1620
Epidermal integrity and wound healing depend on remodeling of cell-matrix contacts including hemidesmosomes. Mutations in beta 4-integrin and plectin lead to... 
PYLORIC ATRESIA | BETA-4 INTEGRIN | PLECTIN | ADHESION | LOCALIZATION | EPIDERMOLYSIS-BULLOSA SIMPLEX | ALPHA-6-BETA-4 INTEGRIN | PHOSPHORYLATION | CELL-MIGRATION | SUBUNIT | DERMATOLOGY
Journal Article
SCIENTIFIC REPORTS, ISSN 2045-2322, 08/2017, Volume 7
The epigenetic writer lysine-specific demethylase 1 (LSD1) is aberrantly upregulated in many cancer types and its overexpression correlates with poor survival... 
MORPHOGENESIS | POPULATION | RENEWAL | STEM-CELLS | EXPRESSION ANALYSIS | PROGENITOR | ADENOCARCINOMA | MULTIDISCIPLINARY SCIENCES | ALPHA-6-BETA-4 | CANCER | PROGRESSION
Journal Article
Gut, ISSN 0017-5749, 10/2017, Volume 66, Issue 10, pp. 1748 - 1760
ObjectiveEpidemiological and clinical data indicate that patients suffering from IBD with long-standing colitis display a higher risk to develop colorectal... 
COLORECTAL CANCER | IBD | CELL MATRIX INTERACTION | INTEGRINS | INTESTINAL BARRIER FUNCTION | CELLS | ALPHA-6-BETA-4 INTEGRIN | INFLAMMATION | ABSENCE | EPIDERMOLYSIS-BULLOSA | INTESTINAL BARRIER | GASTROENTEROLOGY & HEPATOLOGY | TUMOR-GROWTH | EXPRESSION | PROMOTES | BETA | Intestinal Mucosa - metabolism | Intestinal Mucosa - physiopathology | Epithelial Cells - metabolism | Colitis - genetics | Colorectal Neoplasms - genetics | B-Lymphocytes | Hemidesmosomes - physiology | Caspase 1 - metabolism | Colitis - pathology | Hemidesmosomes - genetics | Adenocarcinoma - metabolism | Adenocarcinoma - physiopathology | Mucus - metabolism | Adenocarcinoma - genetics | Integrin alpha6beta4 - metabolism | Cytokines - genetics | Colorectal Neoplasms - metabolism | Adaptive Immunity | Severity of Illness Index | Cytokines - metabolism | Signal Transduction | T-Lymphocytes | Lymphocyte Activation | Myeloid Differentiation Factor 88 - genetics | Integrin alpha6 - genetics | Permeability | Colorectal Neoplasms - physiopathology | Basement Membrane - physiopathology | Animals | Colitis - physiopathology | Keratin-8 - metabolism | Keratin-18 - metabolism | Colitis - metabolism | Mice | Homeostasis - genetics | Intestinal Mucosa - pathology | Complications and side effects | Inflammatory bowel diseases | Antibiotics | Colorectal cancer | Dosage and administration | Research | Epidemiology | Risk factors | Adenocarcinoma | Transformation | Animal models | Epithelial cells | Hyperplasia | Colorectal carcinoma | Helper cells | Homeostasis | Genomes | Lymphocytes T | Small intestine | Defects | Metastases | Keratin | Cell activation | Laminin | Intestine | Hemidesmosomes | Tumorigenesis | Colon | Immune system | Dysplasia | Cytokines | Secretion | Inflammation | Patients | Interleukin 18 | Inflammatory bowel disease | Studies | Lymphocytes B | Colitis | Tumors | Index Medicus | Abridged Index Medicus | Life Sciences | Development Biology | Inflammatory Bowel Disease | 1506
Journal Article
MOLECULAR CANCER RESEARCH, ISSN 1541-7786, 06/2018, Volume 16, Issue 6, pp. 1024 - 1034
Malignant transformation is associated with aberrant N-glycosylation, but the role of protein N-glycosylation in cancer progression remains poorly defined.... 
BISECTING GLCNAC | ALPHA-6-BETA-4 INTEGRIN | METASTASIS | ONCOLOGY | CELL-MIGRATION | LAMININ-332 | N-ACETYLGLUCOSAMINYLTRANSFERASE-V | GLYCOSYLATION | UP-REGULATION | EXPRESSION | CARCINOMA | CELL BIOLOGY
Journal Article
LABORATORY INVESTIGATION, ISSN 0023-6837, 03/2015, Volume 95, Issue 3, pp. 308 - 319
Pancreatic ductal adenocarcinoma (PDA) is a highly aggressive and often lethal malignant tumor. Several studies have shown that epithelial-mesenchymal... 
MEDICINE, RESEARCH & EXPERIMENTAL | ALPHA-6-BETA-4 INTEGRIN | METASTASIS | POOR-PROGNOSIS | GROWTH | TUMOR-CELLS | CELL MIGRATION | PATHOLOGY | CANCER | EXPRESSION | CARCINOMA | MOTILITY
Journal Article
by Yang, ZY and Jiang, H and Qu, Y and Wei, M and Yan, M and Zhu, ZG and Liu, BY and Chen, GQ and Wu, YL and Gu, QL
CARCINOGENESIS, ISSN 0143-3334, 12/2013, Volume 34, Issue 12, pp. 2851 - 2860
MPS-1 (metallopanstimulin-1), also known as ribosomal protein S27, was overexpressed in gastric cancer cells. However, how MPS-1 contributes to gastric... 
BREAST-CANCER | CYTOPLASMIC DOMAIN | SURVIVAL | ALPHA-6-BETA-4 INTEGRIN | METASTASIS | INDUCIBLE FACTOR-I | GENE | ONCOLOGY | COLORECTAL-CANCER | EXPRESSION | CARCINOMA
Journal Article
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