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Molecular Biology of the Cell, ISSN 1059-1524, 07/2013, Volume 24, Issue 13, pp. 2134 - 2145
Journal Article
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, ISSN 0027-8424, 03/2017, Volume 114, Issue 12, pp. E2337 - E2346
Neoplastic cells within individual carcinomas often exhibit considerable phenotypic heterogeneity in their epithelial versus mesenchymal-like cell states.... 
SURVIVAL | PREDICTOR | ITGB4 | MARKER | MULTIDISCIPLINARY SCIENCES | PHENOTYPE | HUMAN BREAST-CANCER | EMT | TUMORS | SLUG | heterogeneity | TRANSITION | mesenchymal | ALPHA-6-BETA-4 | cancer | EXPRESSION
Journal Article
CANCER CELL, ISSN 1535-6108, 11/2004, Volume 6, Issue 5, pp. 471 - 483
Mice carrying a targeted deletion of the signaling portion of the integrin beta4 subunit display drastically reduced angiogenesis in response to bFGF in the... 
CYTOPLASMIC DOMAIN | ALPHA-6-BETA-4 INTEGRIN | ALPHABETA INTEGRIN | TYROSINE PHOSPHORYLATION | ONCOLOGY | ENDOTHELIAL-CELLS | KINASE | BRANCHING MORPHOGENESIS | FIBROBLAST GROWTH-FACTOR | HEMIDESMOSOME FORMATION | TRANSGENIC MICE
Journal Article
JOURNAL OF CLINICAL INVESTIGATION, ISSN 0021-9738, 02/2013, Volume 123, Issue 2, pp. 682 - 699
The contextual signals that regulate the expansion of prostate tumor progenitor cells are poorly defined. We found that a significant fraction of advanced... 
CARCINOMA INVASION | MEDICINE, RESEARCH & EXPERIMENTAL | GROWTH-FACTOR RECEPTOR | ALPHA-6-BETA-4 INTEGRIN | TRANSGENIC ADENOCARCINOMA | EPITHELIAL-CELLS | TYROSINE KINASE | MAMMARY TUMORIGENESIS | FOCAL ADHESION KINASE | GENE-EXPRESSION ANALYSIS | CANCER STEM-CELLS
Journal Article
HEPATOLOGY, ISSN 0270-9139, 12/2016, Volume 64, Issue 6, pp. 2103 - 2117
In patients with hepatocellular carcinoma (HCC) receiving sorafenib, drug resistance is common. HCC develops in a microenvironment enriched with extracellular... 
MIGRATION | INVASION | LAMININ GAMMA-2 | PROGNOSIS | ALPHA-3-BETA-1 INTEGRIN | ALPHA-6-BETA-4 | STROMA | CHEMORESISTANCE | GASTROENTEROLOGY & HEPATOLOGY | CANCER | EXPRESSION
Journal Article
NATURE COMMUNICATIONS, ISSN 2041-1723, 08/2016, Volume 7
Matrix stiffening is a prominent feature of pulmonary fibrosis. In this study, we demonstrate that matrix stiffness regulates the ability of fibrotic lung... 
MATRIX METALLOPROTEINASES | ALPHA-6-BETA-4 INTEGRIN | ACTIVATION | MULTIDISCIPLINARY SCIENCES | RHO-KINASE | P38 MAPK | EXTRACELLULAR-MATRIX | CELL MIGRATION | DIFFERENTIATION | EXPRESSION | PULMONARY-FIBROSIS
Journal Article
Journal Article
by Cao, L and Xu, J
HUMAN PATHOLOGY, ISSN 0046-8177, 03/2017, Volume 61, pp. 222 - 223
Journal Article
PLoS ONE, ISSN 1932-6203, 11/2014, Volume 9, Issue 11, pp. e109026 - e109026
Journal Article
TRENDS IN PHARMACOLOGICAL SCIENCES, ISSN 0165-6147, 10/2007, Volume 28, Issue 10, pp. 506 - 511
The integrins play key roles in the signaling networks that drive pathological angiogenesis and tumor progression. Integrin beta 4 is a laminin receptor... 
CYTOPLASMIC DOMAIN | SIGNAL-TRANSDUCTION | CARCINOMA INVASION | ALPHA-6-BETA-4 INTEGRIN | PHOSPHOINOSITIDE 3-OH KINASE | ALPHABETA INTEGRIN | BETA-4 | BREAST CARCINOMAS | PHARMACOLOGY & PHARMACY | NF-KAPPA-B | EXPRESSION
Journal Article
PLoS ONE, ISSN 1932-6203, 02/2014, Volume 9, Issue 2, pp. e87263 - e87263
The hemidesmosomal transmembrane component collagen XVII (ColXVII) plays an important role in the anchorage of the epidermis to the underlying basement... 
BETA-4 INTEGRIN | ALPHA-6-BETA-4 INTEGRIN | FOCAL ADHESION | PHOSPHOINOSITIDE 3-OH KINASE | ALPHABETA INTEGRIN | ACTIN | PHOSPHORYLATION | HEMIDESMOSOMES | MULTIDISCIPLINARY SCIENCES | PROTEIN EXPRESSION | SQUAMOUS-CELL CARCINOMA | Focal Adhesion Kinase 1 - genetics | Cell Adhesion Molecules - genetics | Autoantigens - metabolism | Carcinoma, Squamous Cell - genetics | Carcinoma, Squamous Cell - metabolism | Carcinoma, Squamous Cell - pathology | Phosphatidylinositol 3-Kinases - metabolism | Autoantigens - genetics | Integrin beta4 - metabolism | Cell Movement - physiology | Neuropeptides - genetics | Focal Adhesion Kinase 1 - metabolism | Skin Neoplasms - pathology | Neoplasm Invasiveness | Non-Fibrillar Collagens - genetics | Neuropeptides - metabolism | Keratinocytes - cytology | Integrin beta4 - genetics | Cell Adhesion Molecules - metabolism | Mice, Knockout | Skin Neoplasms - metabolism | Integrin beta1 - metabolism | Non-Fibrillar Collagens - metabolism | Phosphatidylinositol 3-Kinases - genetics | Animals | Pseudopodia - metabolism | Cell Adhesion - physiology | Keratinocytes - metabolism | Skin Neoplasms - genetics | Pseudopodia - genetics | Signal Transduction - physiology | Mice | Wound Healing - physiology | Integrin beta1 - genetics | rac1 GTP-Binding Protein - metabolism | rac1 GTP-Binding Protein - genetics | Squamous cell carcinoma | Laminin | Collagen | Integrins | Phosphorylation | Motility | Downstream effects | Kinases | Experiments | Cell adhesion & migration | Proteins | Signal transduction | Cell adhesion | Extracellular matrix | Antigens | Dermatology | Invasiveness | Wounds | Keratinocytes | Epidermis | Rac1 protein | Pseudopodia | Adhesion | 1-Phosphatidylinositol 3-kinase | Membrane proteins | Studies | Signaling | Stem cells | Mutation | Focal adhesion kinase | Cell migration | Index Medicus
Journal Article
AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY, ISSN 1044-1549, 04/2017, Volume 56, Issue 4, pp. 413 - 414
Journal Article
CANCER RESEARCH, ISSN 0008-5472, 05/2008, Volume 68, Issue 9, pp. 3204 - 3213
CD151, a master regulator of laminin-binding integrins (alpha(6)beta(4), alpha(6)beta(1), and alpha(3)beta(1)), assembles these integrins into complexes called... 
CARCINOMA INVASION | ALPHA-6-BETA-4 INTEGRIN | ONCOLOGY | TRANSMEMBRANE 4 SUPERFAMILY | CELL-MIGRATION | GENE-EXPRESSION | FOCAL ADHESION KINASE | MICE LACKING | TETRASPANIN CD151 | MEMBER CD151 | MOTILITY
Journal Article