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magnetic resonance spectroscopy (34) 34
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hydrogen-bond distances (33) 33
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research (29) 29
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aib (25) 25
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nmr (18) 18
physiology (18) 18
nuclear magnetic resonance, biomolecular (17) 17
preferred conformation (17) 17
sodium (17) 17
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Clinical Cancer Research, ISSN 1078-0432, 12/2010, Volume 16, Issue 23, pp. 5664 - 5678
Journal Article
Chemical Communications, ISSN 1359-7345, 3/2016, Volume 52, Issue 27, pp. 4852 - 4863
Journal Article
Bioorganic & Medicinal Chemistry Letters, ISSN 0960-894X, 08/2019, Volume 29, Issue 15, pp. 1934 - 1937
The cRGD-conjugated Aib-containing amphipathic helical peptide, MAP(Aib) derivative ( ), has been reported to be a useful carrier for siRNA delivery into... 
α-Aminoisobutyric acid (Aib) | Cell-penetrating peptide (CPP) | Cell selectivity | microRNA | Amphipathic helical peptide | siRNA | RGD | CHEMISTRY, MEDICINAL | alpha-Aminoisobutyric acid (Aib) | INTEGRIN | CHEMISTRY, ORGANIC | AIB | MicroRNA | Peptides | Lysine | Cancer cells | Cancer
Journal Article
JOURNAL OF PHYSICAL CHEMISTRY B, ISSN 1520-6106, 10/2009, Volume 113, Issue 40, pp. 13393 - 13397
Vibrational energy transport in a short 3(10)-helical peptide is Studied by time-resolved femtosecond infrared spectroscopy. The C-D vibrations of... 
ALPHA-AMINOISOBUTYRIC-ACID | MOLECULAR-DYNAMICS | EXCITED-STATE | SPECTROSCOPY | CHEMISTRY, PHYSICAL | RELAXATION | CHAINS | HEME-PROTEINS | BACTERIORHODOPSIN | CARBONMONOXY MYOGLOBIN | FLOW
Journal Article
Chemical Science, ISSN 2041-6520, 2017, Volume 8, Issue 4, pp. 3007 - 3018
Helical oligomers of achiral monomers adopt domains of uniform screw sense, which are occasionally interrupted by screw-sense reversals. These rare, elusive,... 
L-AMINO-ACID | ALPHA-AMINOISOBUTYRIC-ACID | MOLECULAR-DYNAMICS | LINEAR OLIGOPEPTIDES | EXPLICIT SOLVENT | CIRCULAR-DICHROISM | END CONFORMATIONAL COMMUNICATION | ACHIRAL PEPTIDE-CHAIN | SECONDARY STRUCTURE | AMBER FORCE-FIELDS | CHEMISTRY, MULTIDISCIPLINARY | Oligomers | Trapping | Computation | Screws | Inversions | Amino acids | Nuclear magnetic resonance | Habits
Journal Article
Chemical Science, ISSN 2041-6520, 04/2015, Volume 6, Issue 4, pp. 2313 - 2322
Although foldamers, by definition, are extended molecular structures with a well-defined conformation, minor conformers must be populated at least to some... 
ALPHA-AMINOISOBUTYRIC-ACID | LINEAR OLIGOPEPTIDES | SCREW-SENSE PREFERENCE | MACROMOLECULAR HELICITY | CHIRAL PEPTIDES | CHAIN-LENGTH DEPENDENCE | DMSO/MEOD SOLVENT SYSTEM | DYNAMIC NMR-SPECTROSCOPY | HYDROGEN/DEUTERIUM EXCHANGE | AMINO-ACID RESIDUES | CHEMISTRY, MULTIDISCIPLINARY | Oligomers | Residues | Solvents | Molecular structure | Peptides | Decay | Helical | Constants
Journal Article
TETRAHEDRON LETTERS, ISSN 0040-4039, 06/2014, Volume 55, Issue 23, pp. 3418 - 3421
Bending at the valence angle N-C-alpha-C' (tau) is a known control feature for attenuating the stability of the rare intramolecular hydrogen bonded pseudo... 
CATALYSIS | 2.0 Helix | alpha-Aminoisobutyric acid | AMIDE ISOMERIZATION | Isodesmic reaction | AMINO-ACIDS | CHEMISTRY, ORGANIC | Hydrogen bond | Oxazine | MOLECULES
Journal Article
Bioorganic & Medicinal Chemistry Letters, ISSN 0960-894X, 12/2017, Volume 27, Issue 24, pp. 5378 - 5381
Carriers for siRNA: : acetyl-KLULKLULKULKAULKLUG -NH ; : acetyl- KLULKLULKULKAULKLUG-NH ; : acetyl- KLULKLULKULKAULKLUG -NH . The conjugation of Aib-containing... 
α-Aminoisobutyric acid (Aib) | Cell-penetrating peptide (CPP) | Amphipathic helical peptide | siRNA | RGD | SMALL INTERFERING RNA | CELLS | DESIGN | CHEMISTRY, MEDICINAL | alpha-Aminoisobutyric acid (Aib) | AMINO-ACIDS | CHEMISTRY, ORGANIC | TARGETED DELIVERY | Index Medicus
Journal Article
ORGANIC LETTERS, ISSN 1523-7060, 03/2014, Volume 16, Issue 6, pp. 1656 - 1659
Unconstrained gamma(4) amino acid residues derived by homologation of proteinogenic amino acids facilitate helical folding in hybrid (alpha gamma)(n)... 
POLYPEPTIDE HELICES | ALPHA-AMINOISOBUTYRIC-ACID | AMINO-ACIDS | SECONDARY STRUCTURES | FOLDAMERS | CHEMISTRY, ORGANIC | STRUCTURAL-CHARACTERIZATION | BETA-PEPTIDE | HETEROGENEOUS BACKBONES | HYDROGEN-BONDED CONFORMATIONS | CRYSTAL CONFORMATIONS
Journal Article
Angewandte Chemie International Edition, ISSN 1433-7851, 02/2016, Volume 55, Issue 6, pp. 2132 - 2136
Small changes in the structure of a foldamer may lead to gross changes in conformational preference. We show that the simple insertion or deletion of a single... 
photoswitches | peptides | conformation | biocatalysis | foldamers | PEPTIDE MOLECULES | REMOTE STEREOCONTROL | L-AMINO-ACID | LINEAR OLIGOPEPTIDES | INFORMATION | CHEMISTRY, MULTIDISCIPLINARY | CHAIN | ACHIRAL PEPTIDES | ALPHA-AMINOISOBUTYRIC-ACID | HELICAL SCREW-SENSE | PREFERENCE | Hydrogen | Hydrogen bonding | Catalysis | Hydrogen bonds | Asymmetry | Clonal deletion | Insertion | Deletion | Switching | Communications | Communication
Journal Article
JOURNAL OF INHERITED METABOLIC DISEASE, ISSN 0141-8955, 05/2013, Volume 36, Issue 3, pp. 513 - 523
Transport of large neutral amino acids (LNAA) across the blood brain barrier (BBB) is facilitated by the L-type amino acid transporter, LAT1. Peripheral... 
SYSTEM | ALPHA-AMINOISOBUTYRIC-ACID | TRANSPORT | RAT | PHENYLKETONURIA | BARRIER | ENDOCRINOLOGY & METABOLISM | GENETICS & HEREDITY | BRANCHED-CHAIN | PKU | IDENTIFICATION | NORLEUCINE
Journal Article
Molecular Pharmaceutics, ISSN 1543-8384, 06/2019, Volume 16, Issue 6, pp. 2278 - 2295
Journal Article
Chemical Communications, ISSN 1359-7345, 07/2015, Volume 51, Issue 59, pp. 11802 - 11805
Journal Article
Chemical Reviews, ISSN 0009-2665, 1997, Volume 97, Issue 6, pp. 2243 - 2266
  The common problems encountered with the incorporation of three types of amino acids into peptides is discussed along with the specialized synthetic methods... 
TERT-BUTYLOXYCARBONYL | ALPHA-AMINOISOBUTYRIC-ACID | ABSOLUTE-CONFIGURATION | N-METHYLAMINO ACIDS | SOLID-PHASE SYNTHESIS | CHEMISTRY | K DY CHEMISTRY | BIOLOGICALLY-ACTIVE CYCLOPEPTIDES | ENANTIOSPECIFIC TOTAL SYNTHESIS | CYCLOTHEONAMIDE-B | CYCLIC-PEPTIDES | CHLORIDE BOP-CL | Chemical reactions | Amino acids | Chemistry | Peptides
Journal Article