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alpha-amyrin (120) 120
beta-amyrin (72) 72
α-amyrin (52) 52
pharmacology & pharmacy (51) 51
index medicus (45) 45
animals (39) 39
chemistry, medicinal (35) 35
plant sciences (30) 30
β-amyrin (29) 29
oleanolic acid - analogs & derivatives (27) 27
male (25) 25
mice (23) 23
rats (23) 23
biochemistry & molecular biology (21) 21
protium-heptaphyllum (21) 21
chemistry, multidisciplinary (20) 20
triterpenes (19) 19
inflammation (18) 18
integrative & complementary medicine (18) 18
lupeol (17) 17
extract (16) 16
pentacyclic triterpene (15) 15
plant extracts - pharmacology (15) 15
ursolic acid (15) 15
oleanolic acid - pharmacology (14) 14
analysis (13) 13
dose-response relationship, drug (13) 13
mixture (13) 13
saponins (13) 13
terpenes (13) 13
triterpenoids (13) 13
leaves (12) 12
pentacyclic triterpenes (12) 12
plant extracts - chemistry (12) 12
rats, wistar (12) 12
resin (12) 12
triterpenes - chemistry (12) 12
acid (11) 11
extracts (11) 11
chemical-composition (10) 10
constituents (10) 10
humans (10) 10
alpha-amyrin acetate (9) 9
cells (9) 9
chemistry, analytical (9) 9
derivatives (9) 9
essential oil (9) 9
oleanolic acid (9) 9
oleanolic acid - administration & dosage (9) 9
oleanolic acid - chemistry (9) 9
organic chemistry (9) 9
plants (9) 9
research article (9) 9
triterpene (9) 9
triterpenes - pharmacology (9) 9
alpha,beta-amyrin (8) 8
anti-inflammatory agents - pharmacology (8) 8
anti-inflammatory drugs (8) 8
antimicrobial activity (8) 8
antioxidant (8) 8
biosynthesis (8) 8
cytotoxicity (8) 8
essential oils (8) 8
functional expression (8) 8
medicinal-plants (8) 8
oleanolic acid - therapeutic use (8) 8
article subject (7) 7
beta-sitosterol (7) 7
care and treatment (7) 7
edema (7) 7
health aspects (7) 7
inhibition (7) 7
molecular-cloning (7) 7
pharmacology (7) 7
pharmacy (7) 7
plant leaves - chemistry (7) 7
triterpenes - metabolism (7) 7
α-amyrin acetate (7) 7
antioxidant activity (6) 6
beta-amyrin synthase (6) 6
biology (6) 6
biotechnology & applied microbiology (6) 6
burseraceae (6) 6
chromatography (6) 6
edema - drug therapy (6) 6
engineering, chemical (6) 6
fatty acids (6) 6
female (6) 6
hypoglycemic agents - pharmacology (6) 6
mass spectrometry (6) 6
medicine, research & experimental (6) 6
molecular structure (6) 6
oxidative stress (6) 6
oxidosqualene cyclase (6) 6
oxidosqualene cyclases (6) 6
pain (6) 6
phytosterols (6) 6
plant extracts - administration & dosage (6) 6
protium heptaphyllum (6) 6
research (6) 6
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1. Full Text The use of plants in the traditional management of diabetes in Nigeria: Pharmacological and toxicological considerations
by Ezuruike, Udoamaka F and Prieto, Jose M
Journal of Ethnopharmacology, ISSN 0378-8741, 09/2014, Volume 155, Issue 2, pp. 857 - 924
The prevalence of diabetes is on a steady increase worldwide and it is now identified as one of the main threats to human health in the 21st century. In... 
Herb–drug interactions | WHO Traditional Medicine Strategy | Ethnopharmacology | Diabetes | Nigeria | Herb-drug interactions | ZINGIBER-OFFICINALE ROSCOE | IMPROVES INSULIN SENSITIVITY | CHEMISTRY, MEDICINAL | HERBAL PREPARATION ADD-199 | LEAF AQUEOUS EXTRACT | DRUG-METABOLIZING-ENZYMES | RADICAL SCAVENGING ACTIVITY | PLANT SCIENCES | PERFORMANCE LIQUID-CHROMATOGRAPHY | ALDOSE REDUCTASE INHIBITORS | BLOOD-GLUCOSE LEVELS | INTEGRATIVE & COMPLEMENTARY MEDICINE | PHARMACOLOGY & PHARMACY | MASS-SPECTROMETRY ANALYSIS | Hypoglycemic Agents - therapeutic use | Plants, Medicinal - chemistry | Humans | Diabetes Mellitus - drug therapy | Hypoglycemic Agents - pharmacology | Phytotherapy - adverse effects | Animals | Herb-Drug Interactions | Plant Preparations - pharmacology | Plant Preparations - therapeutic use | Medicine, African Traditional | Phytotherapy - methods | Plant Preparations - adverse effects | Hypoglycemic Agents - adverse effects | Medicinal plants | Drugs | Prescribing | Usage | Analysis | Diabetes therapy | Index Medicus
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2. Full Text Triterpenoids from Hibiscus sabdariffa L.with PPAR delta/gamma Dual Agonist Action: In Vivo, In Vitro and In Silico Studies
by Giacoman-Martinez, A and Alarcon-Aguilar, FJ and Zamilpa, A and Hidalgo-Figueroa, S and Navarrete-Vazquez, G and Garcia-Macedo, R and Roman-Ramos, R and Almanza-Perez, JC
PLANTA MEDICA, ISSN 0032-0943, 03/2019, Volume 85, Issue 5, pp. 412 - 423
Hibiscus sabdariffa is a medicinal plant consumed as a diuretic and anti-obesity remedy. Several pharmacological studies have shown its beneficial effects in... 
Hibiscus sabdariffa | Malvaceae | HOMEOSTASIS | CHEMISTRY, MEDICINAL | DELTA | ALPHA | lupeol | DISCOVERY | PLANT SCIENCES | OBESITY | PPAR | ADIPONECTIN | INTEGRATIVE & COMPLEMENTARY MEDICINE | INSULIN-RESISTANCE | CARCINOGENICITY | PHARMACOLOGY & PHARMACY | alpha-amyrin | RECEPTORS | diabetes | GAMMA-AGONIST
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3. Full Text beta-Amyrin, the cannabinoid receptors agonist, abrogates mice brain microglial cells inflammationinduced by lipopolysaccharide/interferon-gamma and regulates M phi(1)/M phi(2) balances
by Askari, VR and Fereydouni, N and Rahimi, VB and Askari, N and Sahebkar, AH and Rahmanian-Devin, P and Samzadeh-Kermani, A
BIOMEDICINE & PHARMACOTHERAPY, ISSN 0753-3322, 05/2018, Volume 101, pp. 438 - 446
Background: Inflammation is a primary response to infection that can pathologically lead to various diseases including neurodegenerative diseases. The purpose... 
MEDICINE, RESEARCH & EXPERIMENTAL | ACTIVATION | ALPHA,BETA-AMYRIN | INTERLEUKIN-1-BETA | MACROPHAGES | LPS/IFN-gamma-induced cell | Inflammation | MTT | NEURODEGENERATIVE DISEASES | Microglia | ALPHA-AMYRIN | beta-Amyrin | INHIBITION | PENTACYCLIC TRITERPENE | PHARMACOLOGY & PHARMACY | CENTRAL-NERVOUS-SYSTEM | EXTRACT
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4. Full Text Supercritical CO2 extraction of α-/β-amyrin from uvaia (Eugenia pyriformis Cambess.): Effects of pressure and co-solvent addition
by Klein, Elissandro Jair and Náthia-Neves, Grazielle and Vardanega, Renata and Meireles, M. Angela A and da Silva, Edson Antônio and Vieira, Melissa Gurgel Adeodato
The Journal of Supercritical Fluids, ISSN 0896-8446, 11/2019, Volume 153, p. 104595
The obtaining of α-/β-amyrin from leaves is a subject with few studies that needs to be explored further in order to extend the understanding about processes... 
Eugenia pyriformis Cambess | α-Amyrin | Supercritical fluid extraction | Co-solvent | β-Amyrin | LIQUID | LEAVES | CHEMISTRY, PHYSICAL | TRITERPENE | ENGINEERING, CHEMICAL | beta-Amyrin | OIL | ANTIOXIDANT | ETHANOL | SEPARATION | alpha-Amyrin | FLUID EXTRACTION
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5. Full Text Identification of oxidosqualene cyclases from the medicinal legume tree Bauhinia forficata: a step toward discovering preponderant α‐amyrin‐producing activity
by Srisawat, Pisanee and Fukushima, Ery Odette and Yasumoto, Shuhei and Robertlee, Jekson and Suzuki, Hideyuki and Seki, Hikaru and Muranaka, Toshiya
New Phytologist, ISSN 0028-646X, 10/2019, Volume 224, Issue 1, pp. 352 - 366
Summary Triterpenoids are widely distributed among plants of the legume family. However, most studies have focused on triterpenoids and their biosynthetic... 
triterpenoid | oxidosqualene cyclase | α‐amyrin | Bauhinia forficata | non‐model legume | CELL-SUSPENSION CULTURES | CATALYTIC ACTION | CATION-PI | non-model legume | STERIC BULK | PLANT SCIENCES | EVOLUTION | TRITERPENE SYNTHASE | SAPONINS | PI INTERACTIONS | BIOSYNTHESIS | FUNCTIONAL-ANALYSIS | alpha-amyrin | Trees | Gas chromatography | Legumes | Metabolites | Triterpenoids | Cloning | Aglycones | Homology | Mass spectroscopy | Gene expression | Mass spectrometry
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6. Full Text Antinociceptive and anti-inflammatory activities of a triterpene-rich fraction from Himatanthus drasticus
by de-Almeida, SCX and da-Silva, ACF and Sousa, NRT and Amorim, IHF and Leite, BG and Neves, KRT and Costa, JGM and Felipe, CFB and Viana, GSD
BRAZILIAN JOURNAL OF MEDICAL AND BIOLOGICAL RESEARCH, ISSN 0100-879X, 2019, Volume 52, Issue 5, p. e7798
Himatanthus drasticus (Mart.) Plumel belongs to the Apocynaceae family and the latex from its trunk bark (Hd) is known as "janaguba milk". This latex is widely... 
MEDICINE, RESEARCH & EXPERIMENTAL | MASLINIC ACID | ALPHA | Inflammation | Himatanthus drasticus | Lupeol | Alpha-amyrin | PENTACYCLIC TRITERPENE | BIOLOGY | Beta-amyrin | HISTONE DEACETYLASE INHIBITORS | Pentacyclic triterpenes | NF-KAPPA-B | MEDICINAL-PLANTS | ATTENUATES ACUTE
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7. Full Text Positive effects of β-amyrin on pentobarbital-induced sleep in mice via GABAergic neurotransmitter system
by Jeon, Se Jin and Park, Ho Jae and Park, Se Jin and Gao, Qingtao and Lee, Hyung Eun and Hong, Eunyoung and Jang, Dae Sik and Shin, Chan Young and Cheong, Jae Hoon and Ryu, Jong Hoon
Behavioural Brain Research, ISSN 0166-4328, 09/2015, Volume 291, pp. 232 - 236
Sleep loss, insomnia, is considered a sign of imbalance of physiological rhythm, which can be used as pre-clinic diagnosis of various neuropsychiatric... 
Sleep | α-Amyrin | GABAA neurotransmitter | Pentobarbital model | β-Amyrin | GABA A neurotransmitter | TARGET | INSOMNIA | MEDICATIONS | MECHANISM | DISORDERS | PALMITATE | NEUROSCIENCES | GABA(A) RECEPTOR SUBTYPES | beta-Amyrin | DRUGS | GABA(A) neurotransmitter | BEHAVIORAL SCIENCES | alpha-Amyrin
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8. Full Text An unusual plant triterpene synthase with predominant alpha-amyrin-producing activity identified by characterizing oxidosqualene cyclases from Malus x domestica
by Brendolise, C and Yauk, YK and Eberhard, ED and Wang, M and Chagne, D and Andre, C and Greenwood, DR and Beuning, LL
FEBS JOURNAL, ISSN 1742-464X, 07/2011, Volume 278, Issue 14, pp. 2485 - 2499
The pentacyclic triterpenes, in particular ursolic acid and oleanolic acid and their derivatives, exist abundantly in the plant kingdom, where they are well... 
CELL-SUSPENSION CULTURES | ARABIDOPSIS-THALIANA | BIOCHEMISTRY & MOLECULAR BIOLOGY | LANOSTEROL SYNTHASE | LUPEOL SYNTHASE | triterpene synthase | OLEANOLIC ACID | ursolic acid | apple | beta-amyrin | FUNCTIONAL EXPRESSION | PENTACYCLIC TRITERPENES | MOLECULAR-CLONING | alpha-amyrin
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9. Full Text Use of supercritical CO2 and ultrasound-assisted extractions to obtain α/β-amyrin-rich extracts from uvaia leaves (Eugenia pyriformis Cambess.)
by Klein, Elissandro Jair and Santos, Kátia Andressa and Palú, Fernando and Vieira, Melissa Gurgel Adeodato and da Silva, Edson Antônio
The Journal of Supercritical Fluids, ISSN 0896-8446, 07/2018, Volume 137, pp. 1 - 8
Uvaia ( Cambess.) leaves were subjected to extraction with supercritical fluid extraction (SFE) and ultrasound-assisted extraction (UAE) under different... 
α-Amyrin | Supercritical fluid extraction | Ultrasound-assisted extraction | β-Amyrin | Eugenia pyriformis C | ALPHA,BETA-AMYRIN | ESSENTIAL OILS | CHEMISTRY, PHYSICAL | PROTIUM-HEPTAPHYLLUM | BY-PRODUCTS | ENGINEERING, CHEMICAL | beta-Amyrin | ANTIOXIDANT | CHEMICAL-COMPOSITION | OPTIMIZATION | alpha-Amyrin | FLUID EXTRACTION | FOOD
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10. Quantitation of alpha amyrin in Scoparia dulcis L. whole plant powder by high performance liquid chromatography
by Katari, Naresh Kumar and Venkatanarayana, M and Deodhar, Parag and Chandra Sekhar, C and Billurc, Ramya
Der Pharma Chemica, 2013, Volume 5, Issue 6, pp. 234 - 240
Alpha amyrin | Method validation | HPLC | Scoparia dulcis
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11. Full Text Selective fractionation and isolation of allelopathic compounds from Helianthus annuus L. leaves by means of high-pressure techniques
by Fuentes-Gandara, F and Torres, A and Fernández-Ponce, M.T and Casas, L and Mantell, C and Varela, R and Martínez de la Ossa-Fernández, E.J and Macías, F.A
The Journal of Supercritical Fluids, ISSN 0896-8446, 01/2019, Volume 143, pp. 32 - 41
The allelopathic potential of L. leaves was study based on bio-directed chemical fractionation approach. Aerial parts of were extracted by means of SFE using... 
Allelopathy | Helianthus annus | Fractionation | Supercritical fluids | Enhanced solvent extraction | BIOACTIVE COMPOUNDS | SUPERCRITICAL CARBON-DIOXIDE | CHEMISTRY, PHYSICAL | BETA-AMYRIN | PROTIUM-HEPTAPHYLLUM | EXTRACTION PROCESS | CO2-EXPANDED ETHANOL | ALPHA-AMYRIN | ENGINEERING, CHEMICAL | SUNFLOWER LEAVES | BLACK TEA | FLUID EXTRACTION | Fatty acids | Sesquiterpenes | Methods | Carbon dioxide | Isoflavones
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