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Journal Article
Journal Article
Journal of Bone and Mineral Research, ISSN 0884-0431, 11/2005, Volume 20, Issue 11, pp. 2053 - 2060
By immunoprecipitation assay, we showed that mouse RANK was self‐assembled through its cytoplasmic domain located at position 534–539, whose domain was... 
TNF receptor‐associated factor | RANK | TNF receptor | receptor oligomerization | osteoclast | Osteoclast | Receptor oligomerization | TNF receptor-associated factor | HUMAN TRAF2 | ALPHA-INDUCED OSTEOCLASTOGENESIS | CD40 | FACTOR RECEPTOR FAMILY | C-FOS | TERMINAL KINASE | STRUCTURAL BASIS | ENDOCRINOLOGY & METABOLISM | DEFECTIVE INTERLEUKIN-1 | NF-KAPPA-B | Recombinant Fusion Proteins - immunology | NIH 3T3 Cells | Immunoprecipitation | Receptor Activator of Nuclear Factor-kappa B | Membrane Glycoproteins - metabolism | Oligopeptides | Gene Expression - genetics | Humans | Peptides - genetics | Tartrate-Resistant Acid Phosphatase | Male | NF-kappa B - metabolism | RANK Ligand | TNF Receptor-Associated Factor 6 - antagonists & inhibitors | Osteoclasts - cytology | Recombinant Fusion Proteins - metabolism | Hemagglutinins - immunology | Acid Phosphatase - metabolism | Transfection | Bone Resorption - genetics | Isoenzymes - metabolism | Bone Marrow Cells - drug effects | Cell Differentiation - physiology | Amino Acid Sequence | Cell Line | Bone Marrow Cells - cytology | Dentin - metabolism | Peptides - immunology | Binding Sites - genetics | Mutation - genetics | Osteoclasts - metabolism | Membrane Glycoproteins - genetics | Peptides - pharmacology | Hemagglutinins - genetics | Carrier Proteins - genetics | Animals | Carrier Proteins - metabolism | TNF Receptor-Associated Factor 6 - metabolism | Protein Binding | Recombinant Fusion Proteins - genetics | Mice | Bone Marrow Cells - metabolism
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 02/2006, Volume 281, Issue 8, pp. 4678 - 4690
Receptor activator of NF-kappa B (RANK) ligand (RANKL) and its receptor RANK play an essential role in osteoclastogenesis and osteoclast function by activating... 
LYMPH-NODE ORGANOGENESIS | TUMOR-NECROSIS-FACTOR | ALPHA-INDUCED OSTEOCLASTOGENESIS | DENDRITIC-CELL | OSTEOPROTEGERIN-LIGAND | KEY REGULATOR | BIOCHEMISTRY & MOLECULAR BIOLOGY | TNF FAMILY-MEMBER | DIFFERENTIATION FACTOR | TERMINAL KINASE | BONE-RESORPTION
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 10/2009, Volume 119, Issue 10, pp. 3024 - 3034
TNF and RANKL mediate bone destruction in common bone diseases, including osteoarthritis and RA. They activate NF-kappa B canonical signaling directly in... 
MEDICINE, RESEARCH & EXPERIMENTAL | TUMOR-NECROSIS-FACTOR | ALPHA-INDUCED OSTEOCLASTOGENESIS | EARLY POSTMENOPAUSAL WOMEN | C-FOS | REGULATE OSTEOCLASTOGENESIS | RECEPTOR ACTIVATOR | DEFECTIVE INTERLEUKIN-1 | DIFFERENTIATION | AUTOCRINE MECHANISM | LIGAND RANKL
Journal Article
Journal Article