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Angiogenesis, ISSN 0969-6970, 06/2009, Volume 12, Issue 2, pp. 177 - 185
Journal Article
Journal of Medicinal Chemistry, ISSN 0022-2623, 09/2018, Volume 61, Issue 17, pp. 7471 - 7473
Integrins are the main cell adhesion mediators on the cell surface. Especially integrin alpha(v)beta(3) has gained a lot of attention as a target in cancer... 
LYMPHANGIOGENESIS | CHEMISTRY, MEDICINAL | ANGIOGENESIS | ALPHA(V)BETA
Journal Article
NATURE CELL BIOLOGY, ISSN 1465-7392, 06/2013, Volume 15, Issue 6, pp. 625 - 625
How different integrins that bind to the same type of extracellular matrix protein mediate specific functions is unclear. We report the functional analysis of... 
ORGANIZATION | INTERACTION DATABASE | ACTIN | ALPHA(V)BETA | ANGIOGENESIS | ALPHABETA | ALPHA-V-BETA-3 | KINASE | CELL-MATRIX ADHESIONS | DYNAMICS | CELL BIOLOGY
Journal Article
NATURE CELL BIOLOGY, ISSN 1465-7392, 05/2014, Volume 16, Issue 5, pp. 457 - U172
Tumour cells, with stem-like properties, are highly aggressive and often show drug resistance. Here, we reveal that integrin alpha(v)beta(3) serves as a marker... 
TARGETED THERAPY | OVEREXPRESSION | METASTASIS | ANGIOGENESIS | ALPHA-V-BETA-3 | ENDOTHELIAL-CELLS | GROWTH | ACQUIRED-RESISTANCE | HUMAN BREAST-CANCER | EXPRESSION | CELL BIOLOGY
Journal Article
NATURE CELL BIOLOGY, ISSN 1465-7392, 06/2012, Volume 14, Issue 6, pp. 584 - 584
Integrin functions are controlled by regulating their affinity for ligand, and by the efficient recycling of intact integrins through endosomes. Here we... 
ACTIVATION | DOMAIN | MEMBRANE | ALPHA-V-BETA-3 | P-SELECTIN | TRAFFICKING | RECEPTOR | EARLY ENDOSOMES | TALIN | EXPRESSION | CELL BIOLOGY
Journal Article
CANCER RESEARCH, ISSN 0008-5472, 10/2008, Volume 68, Issue 19, pp. 7711 - 7717
The cells of origin and mechanisms that underpin tumor heterogeneity in breast cancer are poorly understood. Here, we have examined three mouse models of... 
BREAST-CANCER | ALPHA(V)BETA | EPITHELIUM | ONCOLOGY | INDUCE | RESISTANCE | LEUKEMIA | TUMORS | EXPRESSION | GLAND | TRANSGENIC MICE
Journal Article
SCIENCE, ISSN 0036-8075, 01/2009, Volume 323, Issue 5914, pp. 642 - 644
The cytoskeleton, integrin- mediated adhesion, and substrate stiffness control a common set of cell functions required for development and homeostasis that are... 
SIGNAL-TRANSDUCTION | MEDIATED ADHESION | FORCE | CRYSTAL-STRUCTURE | ALPHA-V-BETA-3 | MULTIDISCIPLINARY SCIENCES | FIBRONECTIN | EXTRACELLULAR-MATRIX | CELL-ADHESION | CATCH BONDS | LIVING CELLS
Journal Article
CLINICAL CANCER RESEARCH, ISSN 1078-0432, 07/2006, Volume 12, Issue 13, pp. 3942 - 3949
Purpose: The integrin alpha(v)beta(3) plays a key role in angiogenesis and tumor cell metastasis and is therefore an important target for new therapeutic and... 
BREAST-CANCER | F-18-GALACTO-RGD | MELANOMA | METASTASIS | ANGIOGENESIS | ONCOLOGY | ALPHA-V-BETA-3 | TUMOR | CELL-ADHESION | ANTAGONISTS | PET
Journal Article
Cancer and Metastasis Reviews, ISSN 0167-7659, 12/2008, Volume 27, Issue 4, pp. 631 - 644
The integrin αvβ3 plays an important role in angiogenesis and tumor metastasis. It is expressed on activated endothelial cells as well as some tumor cells.... 
Molecular imaging | Angiogenesis | Biomedicine | Alpha v beta 3 | Oncology | Cancer Research | Biomedicine general | RGD | Integrins
Journal Article
NATURE COMMUNICATIONS, ISSN 2041-1723, 05/2017, Volume 8
Foot-and-mouth disease virus (FMDV) mediates cell entry by attachment to an integrin receptor, generally alpha v beta 6, via a conserved... 
SYSTEM | SUITE | ALPHA(V)BETA | SPECIFICITY | MULTIDISCIPLINARY SCIENCES | RESOLUTION | CRYSTALLOGRAPHY | OLIGOSACCHARIDE RECEPTOR | GLYCOSYLATION | BINDING
Journal Article
JOURNAL OF CELL BIOLOGY, ISSN 0021-9525, 10/2013, Volume 203, Issue 2, pp. 327 - 343
Keratinocyte mobilization is a critical aspect of wound re-epithelialization, but the mechanisms that control its precise regulation remain poorly understood.... 
CUTANEOUS WOUNDS | REEPITHILIALIZATION | REPAIR | HOMEOSTASIS | ALPHA-V-BETA-6 | CELL-MIGRATION | EPIDERMAL-GROWTH-FACTOR | BETA-1 | EXPRESSION | FORKHEAD TRANSCRIPTION FACTORS | CELL BIOLOGY
Journal Article
JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE, ISSN 0027-8874, 08/2014, Volume 106, Issue 8
Background Integrin alpha v beta 6 promotes migration, invasion, and survival of cancer cells; however, the relevance and role of alpha v beta 6 has yet to be... 
ADJUVANT CHEMOTHERAPY | ACTIVATION | TRASTUZUMAB | ONCOLOGY | GROWTH | INTEGRIN-ALPHA(V)BETA | RESISTANCE | MONOCLONAL-ANTIBODY | HER2 | EXPRESSION | PROGRESSION
Journal Article
NATURE COMMUNICATIONS, ISSN 2041-1723, 01/2015, Volume 6
Angiopoietins regulate vascular homeostasis via the endothelial Tie receptor tyrosine kinases. Angiopoietin-1 (Ang1) supports endothelial stabilization via... 
SELECTIVE-INHIBITION | CELL-JUNCTIONS | ANGIOGENESIS | ALPHA-V-BETA-3 | MULTIDISCIPLINARY SCIENCES | VASCULAR LEAK | VE-CADHERIN | LUNG INJURY | TUMOR-GROWTH | RECEPTOR TYROSINE KINASE | TIE2 RECEPTOR
Journal Article
Chemical Society Reviews, ISSN 0306-0012, 12/2013, Volume 43, Issue 1, pp. 26 - 29
Journal Article
JOURNAL OF CLINICAL MICROBIOLOGY, ISSN 0095-1137, 06/2013, Volume 51, Issue 6, pp. 1714 - 1720
Foot-and-mouth disease (FMD) is a worldwide problem limiting the trade of animals and their products from affected countries. The rapid isolation, serotyping,... 
ALPHA-V-BETA-6 | 3A PROTEIN | SWINE | HOST-RANGE | CATTLE | SENSITIVITY | RECEPTOR | MICROBIOLOGY | INFECTION | CULTURES | NONSTRUCTURAL PROTEINS
Journal Article
Science Translational Medicine, ISSN 1946-6234, 10/2014, Volume 6, Issue 260, pp. 260ra149 - 260ra149
Journal Article
Nature Immunology, ISSN 1529-2908, 08/2015, Volume 16, Issue 9, pp. 907 - 917
Journal Article