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Journal Article
Biochemical and Biophysical Research Communications, ISSN 0006-291X, 03/2019, Volume 511, Issue 1, pp. 129 - 134
The ovarian steroid hormones, estrogen (E2) and progesterone (P4), are essential regulators of uterine biology. The imbalance of these ovarian steroid hormones... 
cPLA2 | Endometrial hyperplasia | MIG-6 | Uterus | PROTEIN | ACID | PROGESTERONE | BIOCHEMISTRY & MOLECULAR BIOLOGY | CANCER | FAILURE | UTERINE | WOMEN | BIOPHYSICS | ALTERED EXPRESSION | RECEPTORS | Immunohistochemistry | Endometrial cancer | Analysis | Estrogen | Phospholipases | Progesterone | Tumors
Journal Article
Journal Article
The Journal of Clinical Endocrinology & Metabolism, ISSN 0021-972X, 06/2007, Volume 92, Issue 6, pp. 2292 - 2299
Aim/Hypothesis: Obesity is associated with increased triacylglycerol (TAG) storage in adipose tissue and insulin resistance. The mobilization of stored TAG is... 
3T3-L1 ADIPOCYTES | SUBCUTANEOUS FAT-CELLS | BETA-ADRENERGIC STIMULATION | WEIGHT-REDUCTION | TISSUE | ENDOCRINOLOGY & METABOLISM | UPPER-BODY OBESITY | PPAR-GAMMA | SKELETAL-MUSCLE METABOLISM | TNF-ALPHA | LIPOPROTEIN-LIPASE | Hyperinsulinism - metabolism | Obesity - diet therapy | Humans | Middle Aged | Sterol Esterase - metabolism | Adipose Tissue - pathology | Male | Lipase - metabolism | RNA, Messenger - metabolism | Diet, Reducing | Obesity - metabolism | Obesity - pathology | Gene Expression Regulation, Enzymologic | Hyperinsulinism - pathology | Regression Analysis | Sterol Esterase - genetics | Biopsy | Insulin Resistance - physiology | Weight Loss - physiology | Adult | Female | Adipose Tissue - enzymology | Hyperinsulinism - diet therapy | Lipase - genetics | Index Medicus | Abridged Index Medicus | Obesity | Sterol Esterase | Biochemistry, Molecular Biology | Insulin Resistance | Lipase | Life Sciences | Weight Loss | Adipose Tissue | RNA, Messenger | Hyperinsulinism | Obesity is associated with increased triacylglycerol (TAG) storage in adipose tissue and insulin resistance. The mobilization of stored TAG is mediated by hormone-sensitive lipase (HSL) and the recently discovered adipose triglyceride lipase (ATGL). The aim of the present study was to examine whether ATGL and HSL mRNA and protein expression are altered in insulin-resistant conditions. In addition | gender | indicating a tight coregulation and transcriptional control. CONCLUSIONS: In obese subjects | Medical and Health Sciences | Medicin och hälsovetenskap | before and just after a 10-wk hypocaloric diet. ATGL and HSL protein and mRNA expression was determined by Western blot and quantitative RT-PCR | and body composition. Both mRNA and protein levels of ATGL and HSL were reduced in insulin-resistant compared with insulin-sensitive subjects (P < 0.05). Weight reduction significantly decreased ATGL and HSL mRNA and protein expression. A positive correlation between the decrease in leptin and the decrease in ATGL protein level after weight reduction was observed. Finally | we investigated whether a possible impaired expression could be reversed by a period of weight reduction. METHODS: Adipose tissue biopsies were taken from obese subjects (n = 44) with a wide range of insulin resistance | respectively. RESULTS: Fasting insulin levels and the degree of insulin resistance (using the homeostasis model assessment index for insulin resistance) were negatively correlated with ATGL and HSL protein expression | Klinisk medicin | independent of fat mass. Data on weight reduction indicated that also other factors (e.g. leptin) relate to ATGL and HSL protein expression | Clinical Medicine | Endokrinologi och diabetes | ATGL and HSL mRNA and protein levels seem to be highly correlated | independent of age | insulin resistance and hyperinsulinemia are strongly associated with ATGL and HSL mRNA and protein expression | fat cell size | Endocrinology and Diabetes
Journal Article
NEUROSCIENCE, ISSN 0306-4522, 04/2013, Volume 236, pp. 345 - 372
The GABA(A) receptor is the main inhibitory receptor in the brain and its subunits originate from different genes or gene families (alpha 1-alpha 6, beta... 
TEMPORAL-LOBE EPILEPSY | mouse brain | KNOCKOUT MICE | NEUROSCIENCES | CEREBELLAR GRANULE CELLS | ADULT-RAT BRAIN | HIPPOCAMPUS | DELTA-SUBUNIT | OLFACTORY-BULB | immunohistochemistry | ALTERED EXPRESSION | TONIC INHIBITION | IMMUNOCYTOCHEMICAL DISTRIBUTION | GABA(A) receptor subunits | in situ hybridization
Journal Article
Annals of Human Genetics, ISSN 0003-4800, 07/2018, Volume 82, Issue 4, pp. 206 - 215
Journal Article
Journal Article
PloS one, ISSN 1932-6203, 10/2018, Volume 13, Issue 10, pp. e0205077 - e0205077
Purpose Human papillomavirus (HPV) infected oropharyngeal squamous cell carcinoma (OPSCC) patients have a better prognosis compared to HPV(-) counterparts.... 
SURVIVAL | GROWTH-FACTOR RECEPTOR | BLADDER-CANCER | LUNG-CANCER | HEAD | P16 IMMUNOHISTOCHEMISTRY | PROGNOSIS | MULTIDISCIPLINARY SCIENCES