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Journal Article
Research in microbiology, 08/2019
Journal Article
Cell Calcium, ISSN 0143-4160, 12/2018, Volume 76, pp. 10 - 22
Prokaryotic and eukaryotic Na /Ca exchangers (NCX) control Ca homeostasis. NCX orthologs exhibit up to 10 -fold differences in their turnover rates ( ),... 
ALLOSTERIC REGULATION | TRANSPORT | NCX | MECHANISM | SODIUM-CALCIUM EXCHANGER | STRUCTURAL BASIS | CA2 | CRYSTAL-STRUCTURE | ALTERNATING ACCESS | NA+-CA2+ EXCHANGER | CELL BIOLOGY
Journal Article
Nature, ISSN 0028-0836, 05/2015, Volume 521, Issue 7552, pp. 322 - 327
Na+/Cl--coupled biogenic amine transporters are the primary targets of therapeutic and abused drugs, ranging from antidepressants to the psychostimulants... 
BIOGENIC-AMINE TRANSPORTERS | COCAINE BINDING | SEROTONIN TRANSPORTER | SUBSTRATE TRANSPORT | BACTERIAL HOMOLOG | MULTIDISCIPLINARY SCIENCES | RAT-BRAIN SYNAPTOSOMES | CONFORMATIONAL DYNAMICS | ALTERNATING-ACCESS | TRANSMITTER UPTAKE | MAMMALIAN-CELLS | Dopamine - chemistry | Dopamine Plasma Membrane Transport Proteins - metabolism | Cocaine - metabolism | Molecular Conformation | Crystallography, X-Ray | Dopamine Plasma Membrane Transport Proteins - chemistry | Methamphetamine - chemistry | Sodium - metabolism | Antidepressive Agents - metabolism | Antidepressive Agents - chemistry | Chlorides - metabolism | Central Nervous System Stimulants - metabolism | Dextroamphetamine - chemistry | Protein Stability | Binding Sites | Dopamine - metabolism | Cocaine - chemistry | Dextroamphetamine - metabolism | Neurotransmitter Agents - metabolism | Models, Molecular | Phenethylamines - metabolism | Cocaine - analogs & derivatives | Methamphetamine - metabolism | Neurotransmitter Agents - chemistry | Animals | Dopamine - analogs & derivatives | Drosophila melanogaster - chemistry | Central Nervous System Stimulants - chemistry | Ligands | Physiological aspects | Neurotransmitters | Dopamine | Research | Neurological research | Biological transport | Methamphetamines | Mutagenesis | Antidepressants | Nervous system | Cocaine | Binding sites | Index Medicus
Journal Article
Cell, ISSN 0092-8674, 01/2019, Volume 176, Issue 3, pp. 435 - 447.e15
Mitochondrial ADP/ATP carriers transport ADP into the mitochondrial matrix for ATP synthesis, and ATP out to fuel the cell, by cycling between cytoplasmic-open... 
adenine nucleotide translocase | bioenergetics | alternating access mechanism | bongkrekate | mitochondria | induced fit | transport mechanism | cardiolipin | adenine nucleotide translocator | NUCLEOTIDE | SYSTEM | BONGKREKIC ACID | SITE | SUBSTRATE | BIOCHEMISTRY & MOLECULAR BIOLOGY | MONOMER | STATE | INHIBITOR | BINDING | ADP | CELL BIOLOGY | Membrane lipids | Cardiolipin | Adenylic acid | Glycine
Journal Article
Cell, ISSN 0092-8674, 01/2018, Volume 172, Issue 1-2, pp. 81 - 89.e10
The multidrug resistance protein MRP1 is an ATP-driven pump that confers resistance to chemotherapy. Previously, we have shown that intracellular substrates... 
outward facing | multidrug resistance | MRP1 | ABCC1 | ABC transporter | cryo-EM | ABC TRANSPORTER | MALTOSE TRANSPORTER | CRYSTAL-STRUCTURE | BIOCHEMISTRY & MOLECULAR BIOLOGY | ALTERNATING ACCESS | EM STRUCTURE DETERMINATION | CRYO-EM | ELECTRON-MICROSCOPY | P-GLYCOPROTEIN | CATALYTIC CYCLE | CELL BIOLOGY | Hydrolysis | Drug resistance in microorganisms | Chemotherapy | Cancer | Index Medicus
Journal Article
Nature Communications, ISSN 2041-1723, 12/2016, Volume 7, Issue 1, pp. 13864 - 13864
ATP-binding cassette (ABC) transporters, a superfamily of integral membrane proteins, catalyse the translocation of substrates across the cellular membrane by... 
ESCHERICHIA-COLI MSBA | CONDUCTANCE REGULATOR CFTR | EXPORTER MSBA | SOLID-STATE NMR | CRYSTAL-STRUCTURE | MULTIDISCIPLINARY SCIENCES | MAS-NMR | ALTERNATING ACCESS | NUCLEOTIDE-BINDING | CONFORMATIONAL CYCLE | P-GLYCOPROTEIN | Index Medicus
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 3/2014, Volume 111, Issue 11, pp. 4049 - 4054
Journal Article