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Vaccine, ISSN 0264-410X, 2009, Volume 27, Issue 52, pp. 7292 - 7298
Journal Article
The Journal of Infectious Diseases, ISSN 0022-1899, 2/2013, Volume 207, Issue 3, pp. 511 - 519
Journal Article
Vaccine, ISSN 0264-410X, 2009, Volume 27, Issue 31, pp. 4104 - 4109
Abstract A Phase 1 study was conducted in 24 malaria naïve adults to assess the safety and immunogenicity of the recombinant protein vaccine apical membrane... 
Allergy and Immunology | Malaria | Falciparum | Apical membrane antigen 1 | APICAL MEMBRANE ANTIGEN-1 | MEDICINE, RESEARCH & EXPERIMENTAL | CONTROLLED-TRIAL | EFFICACY | PROTECTION | NORMAL VOLUNTEERS | AMA1 VACCINE | IMMUNOLOGY | PLASMODIUM-FALCIPARUM MALARIA | CHILDREN | IN-VITRO | ANTIBODY-PRODUCTION | Oligodeoxyribonucleotides - administration & dosage | Adjuvants, Immunologic - administration & dosage | Adjuvants, Immunologic - pharmacology | Antigens, Protozoan - immunology | Humans | Middle Aged | Male | Aluminum Hydroxide - administration & dosage | Plasmodium falciparum - immunology | Vaccines, Synthetic - immunology | Young Adult | Antibodies, Protozoan - blood | Vaccines, Synthetic - adverse effects | Malaria Vaccines - adverse effects | Malaria Vaccines - immunology | Adult | Female | Immunization Schedule | Vaccines, Subunit - adverse effects | Aluminum Hydroxide - pharmacology | Membrane Proteins - immunology | Vaccines, Subunit - immunology | Chemistry, Pharmaceutical | Malaria - prevention & control | Animals | Malaria Vaccines - administration & dosage | Vaccines, Subunit - administration & dosage | Adolescent | Vaccines, Synthetic - administration & dosage | Oligodeoxyribonucleotides - pharmacology | Protozoan Proteins - immunology | Proteins | Hepatitis | Headaches | Nausea | Vaccines | Family medical history | Drug dosages | Blood | Fever
Journal Article
Malaria Journal, ISSN 1475-2875, 08/2016, Volume 15, Issue 1, p. 442
Background: The safety and immunogenicity of PfAMA1, adjuvanted with Alhydrogel (R) was assessed in malaria-experienced Malian adults. The malaria vaccine,... 
Plasmodium falciparum antigen | Immunogenicity | Malaria | Vaccine | Safety | PfAMA1 | Blood-stage | SITE | INFECTIOUS DISEASES | AMA1 | EFFICACY | TROPICAL MEDICINE | IMMUNIZATION | RESPONSES | IMPACT | DIVERSITY | STAGE MALARIA VACCINE | PARASITOLOGY | Adjuvants, Immunologic - administration & dosage | Antigens, Protozoan - immunology | Immunoglobulin G - blood | Vaccines, Subunit - genetics | Humans | Middle Aged | Male | Aluminum Hydroxide - administration & dosage | Plasmodium falciparum - immunology | Vaccines, Synthetic - immunology | Healthy Volunteers | Protozoan Proteins - genetics | Drug-Related Side Effects and Adverse Reactions - pathology | Young Adult | Antibodies, Protozoan - blood | Vaccines, Synthetic - adverse effects | Mali | Malaria Vaccines - adverse effects | Plasmodium falciparum - genetics | Malaria Vaccines - immunology | Adult | Female | Vaccines, Subunit - adverse effects | Antigens, Protozoan - genetics | Gene Expression | Double-Blind Method | Enzyme-Linked Immunosorbent Assay | Membrane Proteins - genetics | Vaccines, Synthetic - genetics | Membrane Proteins - immunology | Recombinant Proteins - genetics | Vaccines, Subunit - immunology | Drug-Related Side Effects and Adverse Reactions - epidemiology | Malaria Vaccines - administration & dosage | Recombinant Proteins - immunology | Vaccines, Subunit - administration & dosage | Adolescent | Pichia - genetics | Plasmodium falciparum - growth & development | Vaccines, Synthetic - administration & dosage | Genetic Vectors | Protozoan Proteins - immunology | Malaria Vaccines - genetics
Journal Article
PLoS One, ISSN 1932-6203, 2012, Volume 7, Issue 6, pp. e38898 - e38898
PLASMODIUM FALCIPARUM: apical membrane antigen 1 (AMA1) is a candidate malaria vaccine antigen expressed on merozoites and sporozoites. The polymorphic nature... 
APICAL MEMBRANE ANTIGEN-1 | TRIAL | IMMUNIZATION | AMA1 | IMMUNOGENICITY | POLYMORPHISMS | CLINICAL MALARIA | BIOLOGY | CANDIDATE | PLASMODIUM-FALCIPARUM MALARIA | BLOOD-STAGE VACCINE | Malaria, Falciparum - prevention & control | Antigens, Protozoan - immunology | Immunity, Humoral - immunology | Humans | Vaccination | Molecular Sequence Data | Antibody Affinity - immunology | Male | Immunoglobulin G - classification | Plasmodium falciparum - immunology | Protozoan Proteins - genetics | Young Adult | Malaria, Falciparum - blood | Immunoglobulin G - immunology | Plasmodium falciparum - genetics | Malaria Vaccines - immunology | Adult | Antigens, Protozoan - blood | Protozoan Proteins - chemistry | Antigens, Protozoan - genetics | Membrane Proteins - blood | Protein Structure, Tertiary | Amino Acid Sequence | Antigens, Protozoan - chemistry | Protozoan Proteins - blood | Enzyme-Linked Immunosorbent Assay | Health | Membrane Proteins - genetics | Membrane Proteins - immunology | Sequence Alignment | Membrane Proteins - chemistry | Alleles | Malaria, Falciparum - immunology | Titrimetry | Plasmodium falciparum - growth & development | Protozoan Proteins - immunology | Health care | Immunoglobulin G | Antibodies | Amino acids | Vaccines | Apical membrane antigen 1 | Blood | Antibody response | Proteins | Sporozoites | Inhibition | Enzyme-linked immunosorbent assay | Vector-borne diseases | Antigens | Immunization | Malaria | Merozoites | Immune response (humoral) | Studies | Adenoviruses | Avidity | Adults | Laboratory animals | Polymorphism
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 7/2007, Volume 104, Issue 30, pp. 12488 - 12493
Antibodies against the malaria vaccine candidate apical membrane antigen-1 (AMA-1) can inhibit invasion of merozoites into RBC, but antigenic diversity can... 
Proteins | Antigens | Reactivity | Enzyme linked immunosorbent assay | Vaccination | Malaria vaccine | Antibodies | Chimeras | Parasites | Parasitemia | Apical membrane antigen-1 | Plasmodium | Invasion | AMA1 | PROTECTION | MULTIDISCIPLINARY SCIENCES | ANTIBODY | apical membrane antigen-1 | RESPONSES | IN-VITRO | IMMUNOGENICITY | POLYMORPHISMS | invasion | PLASMODIUM-FALCIPARUM | BLOOD-STAGE MALARIA | Antigens, Protozoan - immunology | Plasmodium falciparum - immunology | Protozoan Proteins - genetics | Malaria Vaccines - chemistry | Epitopes - immunology | Antigens, Protozoan - metabolism | Protozoan Proteins - metabolism | Plasmodium falciparum - genetics | Malaria Vaccines - immunology | Antibodies - immunology | Plasmodium falciparum - metabolism | Protozoan Proteins - chemistry | Antigens, Protozoan - genetics | Membrane Proteins - metabolism | Plasmodium falciparum - chemistry | Recombinant Proteins - metabolism | Antigens, Protozoan - chemistry | Membrane Proteins - genetics | Models, Molecular | Recombinant Proteins - chemistry | Membrane Proteins - immunology | Recombinant Proteins - genetics | Animals | Membrane Proteins - chemistry | Polymorphism, Genetic - genetics | Epitopes - chemistry | Malaria Vaccines - metabolism | Protozoan Proteins - immunology | Malaria Vaccines - genetics | Antigen-antibody reactions | Viral antibodies | Evaluation | Physiological aspects | Biological Sciences
Journal Article
Journal of Infectious Diseases, ISSN 0022-1899, 06/2016, Volume 213, Issue 11, pp. 1743 - 1751
Journal Article
Journal Article
Human Vaccines & Immunotherapeutics, ISSN 2164-5515, 11/2015, Volume 11, Issue 11, pp. 2705 - 2715
Journal Article
Vaccine, ISSN 0264-410X, 2009, Volume 27, Issue 23, pp. 3090 - 3098
Journal Article
TUBERCULOSIS, ISSN 1472-9792, 09/2016, Volume 100, pp. 118 - 127
Previous studies have shown that the M72/AS01(E) candidate tuberculosis vaccine is immunogenic with a clinically acceptable safety profile in healthy and... 
MYCOBACTERIUM-TUBERCULOSIS | M72/AS01(E) vaccine | CONTROLLED-TRIAL | IMMUNITY | T-cell | EFFICACY | BCG | AMA1 MALARIA VACCINE | MICROBIOLOGY | IMMUNOLOGY | HEALTHY-ADULTS | Tuberculosis | T-CELL RESPONSES | Immunogenicity | RESPIRATORY SYSTEM | PPD-POSITIVE ADULTS | DOUBLE-BLIND | Safety
Journal Article
Journal Article