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Microbial Pathogenesis, ISSN 0882-4010, 12/2019, Volume 137, p. 103779
Antiviral susceptibility screening of avian influenza (AI) H9N2 viruses is crucial considering their role at the animal-human interface and potential to cause... 
Avian influenza | H9N2 | M2 mutations | Amantadine resistance | India
Journal Article
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, ISSN 0002-7863, 07/2019, Volume 141, Issue 29, pp. 11481 - 11488
The amantadine-resistant S31N mutant of the influenza A M2 proton channel has become prevalent in currently circulating viruses. Here, we have solved an X-ray... 
DRUG-BINDING | VIRUS | PROTEIN | MECHANISM | ADAMANTANE RESISTANCE | TRANSMEMBRANE DOMAIN | AMANTADINE RESISTANCE | CHEMISTRY, MULTIDISCIPLINARY | M ION-CHANNEL | HYDROGEN-BONDS | Index Medicus
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 1/2013, Volume 110, Issue 4, pp. 1315 - 1320
The influenza A virus M2 proton channel (A/M2) is the target of the antiviral drugs amantadine and rimantadine, whose use has been discontinued due to... 
Protons | Molecules | Quaternary ammonium compounds | Amines | Influenza A virus | Molecular structure | Drug interactions | Antivirals | Viruses | Ion channels | MOLECULAR-DYNAMICS | PROTEIN | MECHANISM | MULTIDISCIPLINARY SCIENCES | ADAMANTANE RESISTANCE | M2-S31N inhibitor | membrane protein structure | PROTON CHANNEL | NMR | TRANSPORT | A(H3N2) | M2-S31N mutant structure | MUTATIONS | AMANTADINE RESISTANCE | Influenza A virus - chemistry | Viral Matrix Proteins - genetics | Humans | Influenza A virus - genetics | Structure-Activity Relationship | Amantadine - chemistry | Antiviral Agents - chemistry | Drug Design | Nuclear Magnetic Resonance, Biomolecular | Genes, Fungal | Binding Sites | Antiviral Agents - pharmacology | Recombinant Proteins - antagonists & inhibitors | Amantadine - chemical synthesis | Models, Molecular | Recombinant Proteins - chemistry | Recombinant Proteins - genetics | Amantadine - analogs & derivatives | Drug Resistance, Viral - genetics | Viral Matrix Proteins - chemistry | Viral Matrix Proteins - antagonists & inhibitors | Antiviral Agents - chemical synthesis | Mutation | Influenza A virus - drug effects | Amantadine - pharmacology | Influenza viruses | Drug resistance in microorganisms | Physiological aspects | Microbiological chemistry | Research | Health aspects | Biological Sciences | Physical Sciences
Journal Article
Antiviral Therapy, ISSN 1359-6535, 2010, Volume 15, Issue 8, pp. 1151 - 1159
Background: Antiviral drugs are an important option for managing infections caused by influenza viruses. This study assessed the drug susceptibility of 2009... 
INFECTIOUS DISEASES | PERAMIVIR | A(H1N1) VIRUSES | ZANAMIVIR | ADAMANTANE RESISTANCE | AMANTADINE-RESISTANCE | OSELTAMIVIR | H5N1 AVIAN INFLUENZA | NEURAMINIDASE INHIBITOR | VIROLOGY | SURVEILLANCE | PHARMACOLOGY & PHARMACY | ISOLATED WORLDWIDE
Journal Article
Journal Article
JOURNAL OF VIROLOGY, ISSN 0022-538X, 02/2002, Volume 76, Issue 3, pp. 1391 - 1399
The amantadine-sensitive ion channel activity of influenza A virus M-2 protein was discovered through understanding the two steps in the virus life cycle that... 
A VIRUS | INFECTED-CELL SURFACE | M2 PROTEIN | VIROLOGY | NUCLEAR TRANSPORT | FOWL PLAGUE VIRUS | TRANSMEMBRANE DOMAIN | M PROTEIN | AMANTADINE-RESISTANCE | MOUSE PERITONEAL-MACROPHAGES | INTEGRAL MEMBRANE-PROTEIN
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 8/2008, Volume 105, Issue 31, pp. 10967 - 10972
Journal Article
Frontiers in Microbiology, ISSN 1664-302X, 04/2017, Volume 8, p. 741
Recently, novel variants of H5 highly pathogenic avian influenza viruses (AIVs) have been frequently isolated from poultry and wild birds in Asia, Europe and... 
Avian influenza viruses | Eastern China | Subtype H5N2 | Poultry | Reassortant | HUMAN INFECTIONS | poultry | AVIAN INFLUENZA | MALLARD DUCKS | avian influenza viruses | MICROBIOLOGY | GENETIC-CHARACTERIZATION | AMANTADINE-RESISTANCE | subtype H5N2 | eastern China | GENOME SEQUENCE | ZHEJIANG PROVINCE | MIGRATORY BIRDS | reassortant | WILD BIRDS | DOMESTIC DUCKS
Journal Article